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Human Germline Genome Editing – Genetics bodies weigh in on debate with position paper – Lexology (registration)

Posted: Published on August 15th, 2017

In an article published in American Journal of Human Genetics on 3 August 2017, an international group of 11 organisations with genetics expertise has issued a joint position statement, setting out 3 key positions on the question of human germline genome editing: (1) At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human pregnancy. (2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing. There should be no prohibition on making public funds available to support this research. (3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input. This serendipitously timed statement comes on the heels of Shoukhrat Mitalipov and colleagues at Oregon Health and Science Universitys publication of an article in Nature reporting the successful use of … Continue reading

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Poet With Cerebral Palsy Speaks To Early Eugenics Movement – NPR – NPR

Posted: Published on August 15th, 2017

In her book The Virginia State Colony For Epileptics And Feebleminded, poet Molly McCully Brown explores themes of disability, eugenics and faith. Kristin Teston/Persea hide caption In her book The Virginia State Colony For Epileptics And Feebleminded, poet Molly McCully Brown explores themes of disability, eugenics and faith. Growing up in southwestern Virginia in recent decades, poet Molly McCully Brown often passed by a state institution in Amherst County that was once known as the "Virginia State Colony for Epileptics and Feebleminded." Since 1983 the facility, which was founded in 1910, has been called the Central Virginia Training Center, and it is now a residential home for people with various intellectual disabilities. But in the early 20th century, the place Brown now refers to as "the colony" was part of the eugenics movement taking hold in the U.S., and a variety of treatments now considered inhumane were practiced there including forced sterilization. Brown, who has cerebral palsy, notes that had she been born in an earlier era, she might have been sent to live at the institution herself. "It is impossible to know that for sure," she says. "I can look at my life and look at my family and … Continue reading

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Young girl with cerebral palsy has mode of transportation stolen … – BarrieToday

Posted: Published on August 15th, 2017

NEWS RELEASE BARRIE POLICE SERVICE *************************UpdateTuesday, August 15, 2017 The Barrie Police Service has received numerous e-mails, direct messages and telephone calls from the residents of Barrie and the Greater Toronto Area, all wishing to purchase the victim a new ride-on toy car. With the assistance of social media and our media partners Toys R Us has offered to purchase a new ride-on toy for the little girl. The family is overwhelmed by the generosity and would like to thank everyone. The investigation is ongoing. Original release The Barrie Police Service is seeking the publics assistance to find and return a ride-on toy car that belongs to a 10-year-old girl with cerebral palsy. The toy car was stolen from outside a home on Bourbon Circle, Sunday night at 11:30 p.m. A witness reported seeing a male and a young boy drag the toy car away from the side of the home and onto the sidewalk. The child was then observed getting into the toy car and driving it away as the male followed. Any theft is unacceptable, and in this particular incident this theft leaves a 10-year-old girl with limited mobility. The car is not just a toy, it has … Continue reading

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Tim Tebow joins fan with cerebral palsy as she sings ‘God Bless America’ – Fox News

Posted: Published on August 15th, 2017

Tim Tebow had another heartwarming moment Saturday, joining a fan with cerebral palsy as she sang "God Bless America." Tebow, who plays for the St. Lucie Mets, a minor league baseball team affiliated with the New York Mets, joined the fan during a game against the Tampa Yankees. "Moment of the night: fan w/ cerebral palsy sings God Bless America and asked Tebow to join her. This is what it's all about," Jason Woodell tweeted. While Tebow didn't join her in her rendition, his presence beside her was apparently all she needed. Tebow's latest act of kindness comesafter a video went viralshowing the ex-NFL quarterback forsaking practice swings prior to an at-bat to shake an autistic boys hand -- and followed it up with a monster three-run home run. Tebows three-run homer on July 29 lifted the St. Lucie Mets to a 10-3 victory over the Charlotte Stone Crabs. Tebow is hitting .238 with a .305 on-base percentage and five home runs for St. Lucie. He's hit eight home runs with two teams this season. Continued here: Tim Tebow joins fan with cerebral palsy as she sings 'God Bless America' - Fox News … Continue reading

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Tips for Being an Excellent Teacher to Students With Disabilities – Cerebral Palsy News Today

Posted: Published on August 15th, 2017

As the summer closes, our attention turns toward school. School bags, pencils, crayons and other school supplies are at the forefront of parents and students minds. When the student has a disability, however, there are many other aspects to think through and be prepared to handle. If you are a teacher with a student who has a disability, there are many suggestions that you can use not only to make you a successful teacher, but also help your student be more comfortable and ready to learn. The first step on your to-do list is to research the disability of the student. I sat through an entire individualized education plan (IEP) meeting once, and the mainstream teacher continued to say that the student had multiple sclerosis instead of cerebral palsy. Please avoid this embarrassment and do research. As you research, keep in mind that each student is an individual. So, you might know the facts about the disability, but each disability affects the person in unique ways. If your student uses a wheelchair or mobility device, it might be tempting to have him or her sit in the very front of class. Now its your time to be creative. Students who … Continue reading

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Eight-year-old Elvis Presley fan with cerebral palsy enjoys ‘absolutely fantastic’ holiday to home of his hero – Lancashire Telegraph

Posted: Published on August 15th, 2017

AN eight-year-old avid Elvis Presley fan with cerebral palsy was 'all shook up' after having a holiday at the home of his hero. Blackburn's Samuel Hosker has been on an 'absolutely fantastic' weeklong trip to Graceland, the former home of Elvis Presley in Memphis, Tennessee. An anonymous businessman paid for the child and his parents to enjoy the trip, who heard about Samuel's love of Elvis after his parents set up a now completed campaign to raise 30,000 for surgery not available on the NHS. The family even got to enjoy an extra day in America after a flight mix up meant they had an extra days stay paid for. Mother Michelle Hosker, 39, said their stay at the Guest House Hotel, which was located on the Graceland Estate, was 'amazing' for all of them. She said: "It was absolutely fantastic. "Samuel absolutely loved every minute of it. "He was singing along to all the songs. "Memphis is just Elvis mad, there is Elvis everywhere. "It was just perfect for Samuel, it was a dream come true." More than 60,000 has been raised in total for Samuel, who will now undergo an operation in September which will prevent him being … Continue reading

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Researchers Develop Newborn Screening Tool for Duchenne – Muscular Dystrophy News

Posted: Published on August 15th, 2017

Cardiff Universityscientists, partneringwith the biotech company PerkinElmer, have developed a diagnostic kit to screen for Duchenne muscular dystrophy (DMD) in newborns using dried blood spots, according to researchers. The study, Characterization of a Blood Spot Creatine Kinase Skeletal Muscle Isoform Immunoassay for High-Throughput Newborn Screening of Duchenne Muscular Dystrophy, was published in the journal Clinical Chemistry. This new diagnostic method works by detecting the presence of the enzyme CK-MM, which is elevated in patients with DMD due to muscle damage. The test was created by Dr. Ian Weeks, a professor at Cardiff Universitys School of Medicinein Wales and the lead author of the study. The test was then adapted into an existing assay developed by PerkinElmer. The successful outcome of this study is an example of the impact that can be achieved through collaboration between academic, clinical and industry colleagues in developing improvements in human healthcare, Weeks said in a press release. Previous attempts at developing a diagnostic kit using blood spot CK (creatinine kinase) enzyme assays were met with little success because the tests were nonspecific and the results were unreliable. This is due to the fact that prior tests could not distinguish between the three different forms of … Continue reading

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SHEBOYGAN Fire Fighters Support MDA with Annual Fill the Boot Drive – WHBL Sheboygan

Posted: Published on August 15th, 2017

Tuesday, August 15, 2017 8:13 a.m. CDT by Jon DeMaster SHEBOYGAN, Wis. (WHBL) - The Sheboygan Fire Department Local 483 is showing its support for the Muscular Dystrophy Association as its members kick off the annual Fill the Boot fundraising campaign to help kids and adults with muscular dystrophy, ALS and related muscle-debilitating diseases live longer and grow stronger. It will take place August 17th and 18th. Continuing a more than 60 year tradition, twenty dedicated fire fighters from Sheboygan Fire Department Local 483 will hit the streets with boots in hand asking pedestrians, motorists, customers and other passersby to make a donation to MDA, they will be at the intersection of 25th and Superior and 8th Street and Erie between 11am 5:00pm both days. We are thrilled to be working with the Sheboygan Fire Department Local 483 for another year of Fill the Boot to help provide the funds needed to find treatments and cures for muscular dystrophy, ALS and related diseases that severely limit strength and mobility, said Fundraising Coordinator Murphy Maes. The dedication of these fire fighters to MDAs mission is unwavering, spending countless hours both with Fill the Boot and MDA Summer Camp to care for … Continue reading

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Cardiac stem cells rejuvenate rats’ aging hearts, study says – CNN – CNN

Posted: Published on August 15th, 2017

The old rats appeared newly invigorated after receiving their injections. As hoped, the cardiac stem cells improved heart function yet also provided additional benefits. The rats' fur fur, shaved for surgery, grew back more quickly than expected, and their chromosomal telomeres, which commonly shrink with age, lengthened. The old rats receiving the cardiac stem cells also had increased stamina overall, exercising more than before the infusion. "It's extremely exciting," said Dr. Eduardo Marbn, primary investigator on the research and director of the Cedars-Sinai Heart Institute. Witnessing "the systemic rejuvenating effects," he said, "it's kind of like an unexpected fountain of youth." "We've been studying new forms of cell therapy for the heart for some 12 years now," Marbn said. Some of this research has focused on cardiosphere-derived cells. "They're progenitor cells from the heart itself," Marbn said. Progenitor cells are generated from stem cells and share some, but not all, of the same properties. For instance, they can differentiate into more than one kind of cell like stem cells, but unlike stem cells, progenitor cells cannot divide and reproduce indefinitely. Since heart failure with preserved ejection fraction is similar to aging, Marbn decided to experiment on old rats, ones that … Continue reading

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UCLA scientists identify a new way to activate stem cells to make hair grow – UCLA Newsroom

Posted: Published on August 15th, 2017

UCLA researchers have discovered a new way to activate the stem cells in the hair follicle to make hair grow. The research, led by scientists Heather Christofk and William Lowry, may lead to new drugs that could promote hair growth for people with baldness or alopecia, which is hair loss associated with such factors as hormonal imbalance, stress, aging or chemotherapy treatment. The research was published in the journal Nature Cell Biology. Hair follicle stem cells are long-lived cells in the hair follicle; they are present in the skin and produce hair throughout a persons lifetime. They are quiescent, meaning they are normally inactive, but they quickly activate during a new hair cycle, which is when new hair growth occurs. The quiescence of hair follicle stem cells is regulated by many factors. In certain cases they fail to activate, which is what causes hair loss. In this study, Christofk and Lowry, of Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, found that hair follicle stem cell metabolism is different from other cells of the skin. Cellular metabolism involves the breakdown of the nutrients needed for cells to divide, make energy and respond to their … Continue reading

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