InVivo Therapeutics (NASDAQ:NVIV) perks up13%premarket on modest volume in response to its announcement that two spinal cord injury patients in the INSPIRE study who received its Neuro-Spinal Scaffold have improved from sensory incomplete AIS B status to motor incomplete AIS C, the second and third patients to reach this level. CEO and ChairmanMark Perrin says, We are excited that these two patients have continued to progress beyond the period of early improvement. Three of the five patients with an AIS conversion in INSPIRE have demonstrated motor recovery and are now classified as AIS C conversions. Having assessments of motor improvements occurring one or two years post-implantation is uncommon and may be indicative of prolonged neural repair. TheNeuro-Spinal Scaffoldis a bioresorbable polymer scaffold that is designed to treat acute spinal cord injury. It is implanted at the injury site within a spinal cord contusion where it provides structural support to spinal tissue and a supportive matrix that facilitates endogenous tissue repair. It degrades over a period of several weeks. Previously: InVivo to amend INSPIRE protocol, up to 40 new patients to participate; shares slump 6% on efficacy implications (April 13) Read the rest here: Two spinal cord injury patients show improvement … Continue reading →

CAMBRIDGE, Mass.--(BUSINESS WIRE)--InVivo Therapeutics Holdings Corp. (NVIV)today announced that the UCHealth Memorial Hospital in Colorado Springs, CO has been added as a clinical site for The INSPIRE Study: InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury. Thomas Schroeppel, M.D., has been named Principal Investigator at the site. I am thrilled to bring The INSPIRE Study and this innovative technology to the UCHealth Memorial Hospital, especially to help those who suffer from the devastating condition of spinal cord injury, Dr. Schroeppel said. Mark Perrin, InVivos CEO and Chairman, said, We are pleased to have Dr. Schroeppel and his team as part of the INSPIRE study. The UCHealth Memorial Hospitals experience with spinal cord injury will be a valuable asset to the INSPIRE study as we look to completing enrollment. There are now 32 clinical sites participating in the clinical study: For more information, please visit the companys ClinicalTrials.gov registration site: http://clinicaltrials.gov/ct2/show/study/NCT02138110 About the Neuro-Spinal Scaffold Implant Following acute spinal cord injury, surgical implantation of the biodegradable Neuro-Spinal Scaffold within the decompressed and debrided injury epicenter is intended to support appositional healing, thereby reducing post-traumatic cavity … Continue reading →

By Jesse Pound, Staff Writer Photo: Photos By John Davenport /San Antonio Express-News Manuel A. Riquelme works in a lab Friday at UT Health San Antonio. UT Healths licensing deal with gAlaMab Therapeutics is based on the work of researcher Jean Jiang. Manuel A. Riquelme works in a lab Friday at UT Health San Antonio. UT Healths licensing deal with gAlaMab Therapeutics is based on the work of researcher Jean Jiang. UT Health San Antonio signs potential $114M deal with Chinese pharma firm UT Health San Antonio announced Friday a landmark licensing deal worth up to $114 million with a Chinese pharmaceutical company to develop new treatments for spinal cord injuries and breast cancer. AlaMab Therapeutics, a subsidiary of CSPC Pharmaceutical Group in China, will make an upfront payment of $4.5 million to UT Health San Antonio and UTHealth in Houston to license two antibodies found by local researcher Jean Jiang. The first antibody inhibits neural inflammatory reactions after spinal cord injury, while the other helps treat breast cancer after it invades the bone. Jiang has partnered with Zhiqiang An of UTHealth in Houston to humanize the antibodies for more trials. Dr. William Henrich, president of UT Health San Antonio, … Continue reading →

This form of alternative care typically treats mechanical disorders of the musculoskeletal system with an emphasis on the spine, although I have had chiropractors adjust my hips, feet and shoulders. Chiropractic care is somewhat controversial with mainstream practitioners, including some who believe it is sustained by pseudo-scientific ideas such as subluxation and "innate intelligence" that are not based on sound research. In my own reviews of studies on chiropractic manipulation, I have not found evidence that it is effective long term for chronic pain, except for treatment of back pain. However, chiropractic care is well established in the U.S. and Canada as a form of alternative treatment. It is often combined with other manual-therapy professions, including massage therapy, osteopathy and physical therapy. Craniosacral Therapy Craniosacral therapy (CST) takes a whole-person approach to healing, and the inter-connections of the mind, body and spirit. Practitioners say it is an effective form of treatment for a wide range of illnesses, and encourages vitality and a sense of well-being. Because it is non-invasive, it is suitable for people of all ages, including babies, children and the elderly. The intent of CST treatment is to enhance the body's own self-healing and self-regulating capabilities. This is … Continue reading →