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Muscle growth finding may assist with cancer treatment – Medical Xpress

Posted: Published on June 14th, 2017

June 13, 2017 Dr Craig Harrison and Dr Kelly Walton from the Monash BDI. Credit: Monash University Monash University's Biomedicine Discovery Institute (BDI) researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer. The approach, jointly developed with Baker Heart and Diabetes Institute scientists, combines - for the first time - molecules that inhibit three proteins which in turn repress muscle growth. Published this week in the journal Proceedings of the National Academy of Sciences, the scientists found that inhibiting activin A, activin B and myostatin resulted in skeletal muscle mass increase by as much as 150 per cent in preclinical models. Myostatin has long been recognised as the body's major negative regulator of skeletal muscle mass, helping to maintain muscle homeostasis in the body, but creating molecules to target all three related proteins together was a novel approach. "As a result of the study we can now more precisely regulate - and increase - muscle mass in the setting of disease," co-lead author from Monash BDI, Dr Craig Harrison, said. Dr Harrison said the study, the culmination of many years of … Continue reading →

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Girl overcomes weakness causedby Cerebral Palsy – MyDaytonDailyNews

Posted: Published on June 14th, 2017

More than 200,000 cases of cerebral palsy (CP), a condition caused by brain damage before or during birth, are diagnosed each year, usually in small children. Most people with CP will eventually lose the use of their limbs and become wheelchair bound since the part of the brain that has been damaged affects movement, posture and balance. Kelsey Applegate of Lebanon was diagnosed with CP when she was 2 years old. Since that time, Applegate has tried a variety of leg braces and even Botox treatments, none of which helped her long term. After a physical therapist told her to get a wheelchair a few years ago, Applegate refused to give in and lose all her independence. Today, she has defied the odds and, through hard work and effort, has managed to build up strength in her legs and body. My therapist and my doctor urged me to get a wheelchair, Applegate said. I also had braces and crutches. Applegate and her mom did some research and felt encouraged when they learned that a personal fitness trainer might be able to help. My mom went into Anytime Fitness to see if anyone there could help me, Applegate said. She met … Continue reading →

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The SFA have killed our World Cup dreams says heartbroken cerebral palsy captain – Scottish Daily Record

Posted: Published on June 14th, 2017

THE skipper of Scotlands cerebral palsy footballers has accused the SFA of killing their sporting dreams. Hard-hearted Hampden bosses have withdrawn the Scotland team from the World Championships in Argentina to protect its independence with FIFA . But Jonny Paterson has accused the SFA of treating him and his team-mates as second-class citizens and fears disabled players have just lost their international side ranked ninth in the world forever. The SFA moved after the governing body of cerebral palsy football, the IFCPF, changed its rules to allow any player with a British passport to represent a home nation of their choice. A statement said: The SFA believes that continued participation in IFCPF competitions may potentially jeopardise Scotlands status as an independent football nation. But midfielder Paterson said: Im devastated for myself and my team-mates, who have given up so much to reach this level in the game. Theres nothing for us any more even our next training get-together on June 24 has been scrapped. Ive overcome disability and bullying as a kid as I fought to play football before finally finding acceptance with Blackburn Boys Club in Motherwell. This is harder to take than all of that. If the SFA … Continue reading →

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Maharashtra Class 10 results: Teen with cerebral palsy scores 88%, completes tough ‘yatra’ after exams – Hindustan Times

Posted: Published on June 14th, 2017

Gritty Mumbai teen diagnosed with cerebral palsy, a neurological condition that restricts movement, bagged 88% in the Maharashtra Boards (MSBSHSE) Secondary School Certificate (SSC) Class 10 results, announced on Tuesday. Whats more, she recently climbed 3, 500 steps (one way) 99 times in 40 days - a rare feat - during a festival celebrated by the Jain community. Drashti Dhruv, 16, has been living with cerebral palsy since birth. She cannot hold a pen or write straight as her hand trembles violently. Her condition, however, has never stopped her from pushing harder to achieve goals - and clearing the SSC or Class 10 exam was a major one. I am happy with my marks, it was more than I expected, said Dhruv, a student of Swami Vivekananda International School, Kandivli. The board allowed me to take help from a writer during exams. I feel good to have challenged myself. Shes very disciplined with studies, and for the Class 10 boards she recorded her lessons on a mobile phone and revised them at leisure. In the last two months before the exam, Drashti burnt the midnight oil, said her father. She was confident that her hard work will pay off and … Continue reading →

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University of Alberta research brings hope for spinal cord injury victims – Lexology (registration)

Posted: Published on June 14th, 2017

Neuroscientists at the University of Alberta recently made significant discoveries about spinal injuries which could lead to new treatment options. Specifically, the research focused on the role blood flow and oxygen play in motor function post-injury. Healthcare workers and spinal cord injury lawyers are understandably excited about the potential of this new information. The biggest finding is really that we found that blood vessels, these capillaries, are controlled by cells that nobody really knew anything about, Karim Fouad, Canada Research Chair in spinal cord injury and a co-author of the study told the Edmonton Journal. Just that knowledge opens so many windows, so many opportunities for treatments of various diseases and injuries of the brain and spinal cord. Previous research suggested that limited post-injury blood flow to the spinal cord was a temporary problem; the University of Alberta team believes they have evidence to the contrary and have identified pericytes, tiny cells that wrap around blood vessels, as the source of this issue. It turns out the blood flow below a spinal cord injury the whole length of the spinal cord below an injury is permanently impaired because of these pericytes excessively contracting, explained the studys co-senior author, David Bennett. … Continue reading →

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Brain Cells From Pigs Implanted Into Human Brains to Treat Parkinson’s – Futurism

Posted: Published on June 14th, 2017

In Brief Researchers have used transplanted choroid plexus brain cells from pigs to treat people with Parkinson's disease with promising results. Placebo-controlled trials have now begun in what may be the a step toward a treatment for millions of people. Neurochemical Reboot New Zealand biotech company Living Cell Technologies has developed a treatment for Parkinsons disease using choroid plexus cells from pigs. These cells are found in the area of the brain that manufactures a mix of signaling molecules and growth factors that maintain nerve health, so the researchers transplanted the healthy cells from pig donors into four human subjects. 18 months post surgery, the results are still promising, so researchers began a placebo-controlled trial in 18 additional patients in May. Parkinsons disease is characterized by the progressive loss of dopamine-making brain cells. Dopamine itself helps the brain control movement in the body. The aim of this treatment is to nourish existing healthy brain cells in recipients to slow or prevent further loss. Thus far, the technique has proven successful in the treatment of rats with a species-specific corollary of Parkinsons disease. Its putting in a little neurochemical factory to promote new nerve cell growth and repair, Ken Taylor of … Continue reading →

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Hong Kong biotech start-up claims world first in stem cell treatment of Alzheimer’s and Parkinson’s diseases – South China Morning Post

Posted: Published on June 14th, 2017

Oper Technology, a Hong Kong biotechnology start-up, has pioneered what it claims is a world first in stem cell treatment that it says could potentially help millions of patients suffering from Alzheimers and Parkinsons diseases. The business was co-founded by Hong Kong Baptist Universitys Professor Ken Yung, who specialises in neurobiology and neurological diseases in the universitys biology department. He and his team has now developed a method of harvesting neural stem cells from the brains of live subjects using specially developed nanoparticles. The exploration of using stem cells to repair damaged neural cells is not a new concept. Scientists in the US and elsewhere have experimented using stem cells from fat and skin, developing them into neural cells. But Yung claims his team is the first to successfully harvest stem cells directly from the brain and re-inject the developed neural cells back into a live subject, thereby artificially regenerating any cells which have died off, due to neurological diseases from neural stem cells themselves. Stem cells have the potential to develop into different types of cells with specialised functions. The nanoparticles which are made of a type of iron oxide work like magnets to attract the stem cells within … Continue reading →

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18000 now use medical marijuana in CT – The CT Mirror

Posted: Published on June 14th, 2017

Arielle Levin Becker / CTMirror.org Medical marijuana products available for sale at Prime Wellness, a dispensary in South Windsor. The recreational marijuana debate is tabled for now, but 18,000 Connecticut residents are using the drug to help with specific debilitating medical conditions. Medical marijuana was legalized in May of 2012 and put into practice in September of 2014. In the five years since its legalization, the number of dispensaries grew from six to nine. The number of patients in Connecticut now stands over 18,000. Regulations expanded to allow minors with certain serious illnesses to use medical marijuana. St. Francis Hospital and Medical Center began testing the drug as an alternative to opioids. Connecticut Drug Control Division director Rod Marriott said the program is well-received by patients. Its always great to hear about a patient thats using a product from medical marijuana in Connecticut thats helping them to have a better quality of life, Marriott said. Among the 22 qualifying conditions are cancer, glaucoma, HIV/AIDS, Parkinsons, multiple sclerosis, epilepsy, post-traumatic stress disorder, cerebral palsy and cystic fibrosis. Marriott estimates about 7,000 new patients are added each year. Its difficult to determine how the number of patients in Connecticut stacks up against … Continue reading →

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TBI: Initial Treatment of Traumatic Brain Injury

Posted: Published on June 14th, 2017

Initial treatment of a Traumatic Brain Injury (TBI) begins upon arrival to a hospital. At the hospital, a team of medical professionals, generally led by the trauma surgeon, will meet the patient. The trauma surgeon, acting as the leader, will direct the team. The trauma staff will initiate resuscitation procedures, monitor the bodys vital functions, respond to potential life-threatening changes and coordinate care with other hospital personnel. The patient may need surgery for injuries. In addition to the trauma surgeon, the surgical staff could include the neurosurgeon, a physician who performs brain and spinal cord surgery; an orthopedic surgeon, a physician who works with broken bones such as fractures of the arms and legs or the spinal column; or a general surgeon. While the physicians are assessing the patient and the response to treatment, the trauma nurse is caring for the patient: providing resuscitation, stabilization and supportive care. The nurses have the responsibility to coordinate and provide communication within the hospital and with the family. Once stabilized, the patient will be transferred to a specialized trauma care unit. Care will be provided by the critical care nursing staff. The nursing staffs responsibility is to assess, monitor and interpret vital physiologic … Continue reading →

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Can Emergency Rooms Fail to Diagnose Traumatic Brain Injuries? – LongIsland.com

Posted: Published on June 14th, 2017

Nearly two million traumatic brain injuries occur every year in the US. Reports have shown that emergency rooms can fail to diagnose or even document certain types of head trauma. Whereas something as noticeable as a cracked skull will generally be immediately diagnosed, subtler types of head injuries may not be caught by the first doctors to examine them. If a patient then follows up with other medical providers after the first ER trip, the lack of documentation and diagnoses on TBIs can lead to further delays in treatment. Complicating the issue further, some physicians are not experienced in mild traumatic brain injuries, preventing them from recognizing the signs of a TBI in the weeks after an accident. If the patient is relying on his insurance company to choose a doctor for treatment, the insurance company may select one that does not have experience in traumatic brain injuries as well. Dangers of Delayed Diagnosis with Traumatic Brain Injuries Of course, a delay in diagnosis means a delay in treatment for the traumatic brain injury. This is especially troubling in matters concerning the brain, as failure to treat the injury in quickly can cause more severe, long term problems to arise … Continue reading →

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