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A new tool to decipher evolutionary biology — ScienceDaily – Science Daily

Posted: Published on May 11th, 2017

Understanding evolution is one of the cornerstones of biology -- evolution is, in fact, the sole explanation for life's diversity on our planet. Based on the evolution of proteins, researchers may explain the emergence of new species and functions through genetic changes, how enzymes with novel functions might be engineered, or, for example, how humans are related to their closest relatives such as gorillas or bonobos. One popular approach to the study of evolution is to compare genome data using bioinformatics (computer-aided) tools. Scientists using these approaches may compare specific proteins, which consist of combinations of 20 universal building blocks, called amino acids. So far, the bioinformatics tools used to study the evolution of single proteins have assumed that the speed at which different regions of proteins evolve can be modeled with a statistical distribution whose shape is determined by a single variable. "That assumption, however, does not reflect reality, and it might have led to a large proportion of biased phylogenetic results being published over the last two decades or so," explains Minh Quang Bui, from the Center for Integrative Bioinformatics (CIBIV) and co-author of the study. A new algorithm allows insights into protein evolution Arndt von Haeseler, group … Continue reading

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Virginia Western joins international project to provide biology students with hands-on research – Roanoke Times

Posted: Published on May 11th, 2017

Virginia Western Community College is one of 15 institutions in the United States to become part of the 10th cohort to participate in the Howard Hughes Medical Institutes (HHMI) Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science project (SEA-PHAGES). The project is intended to spark an interest in science among students by teaching them to creatively and critically use the scientific method to address real-world issues. Thus far, 142 colleges and universities, including Carnegie Mellon, James Madison University, Virginia Tech and Johns Hopkins University, have participated in SEA-PHAGES. Virginia Western is the only community college in Virginia that has been selected to participate. Training for Virginia Western faculty begins this summer and the project will be available to students as part of a two-semester course of study starting Fall Semester 2017. This is an exciting opportunity for students at Virginia Western to be introduced to the scientific method while significantly contributing and connecting to the larger scientific community, says Amy White, Dean of STEM. Our aim, along with HHMIs mission, is to contribute to the scientific body of knowledge and inspire future scientists. Open enrollment for Virginia Westerns Fall Semester will begin on June 21; returning students may … Continue reading

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NIMR holds 2017 Molecular Biology Workshop – Vanguard

Posted: Published on May 11th, 2017

By Oluwatobi Alabi OLECULAR Biology and Biotechnology Department of Nigeria Institute of Medical Research (NIMR) will be holding its seventh Annual Molecular Biology Hands-on-Training workshop. The 2017 Molecular Biology Hand-on-training workshop with the theme: Protein Expression is schedule to hold from August 7-11, 2017 at NIMR conference room, Yaba, Lagos. Areas which the conference will focus on during the five-day Hands-on-Training workshop include: Current Methods in Molecular Biology,Ethical issues of challenges in Genetic Research, Molecular Evolution of viruses of Public Health Importance: from Genomics to Proteomics, Introduction and Principles of SDS-PAGE and Basic Protein Interaction Techniques. Also, there will be practical sessions on PCR, SDS-PAGE and Western Blotting. The Molecular Biology hands-on-Training workshop started in 2009 with the theme Molecular Biology and Biotechnology: Roadmap to Specific Diagnosis. The themes for the previous years are: Molecular Biology: The Backbone of Evidence-based Medicine (2010); Role of Molecular Biology and Biotechnology in Research and Development (2011); Emerging Infectious Diseases: Combating multi-drug resistance using molecular biology approach (2012); The Importance of Molecular Biology Typing Techniques in Disease Mapping (2013); Practical Applications of Genetic Markers (2014). The idea of MBBT hands-on-training workshop was first muted informally in 2007/2008. In 2009, a total of 48 participants … Continue reading

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Finding family beyond biology – The Panther

Posted: Published on May 11th, 2017

Guest column by Nishaa Sharma, sophomore strategic and corporate communications and peace studies major Nishaa Sharma, sophomore strategic and corporate communications and peace studies major I remember the exact moment I realized that the word family means something different for everybody. I was a freshman, getting ready to go to my first high school dance which was our winter formal. My parents had been divorced for five years, and I was living with my sister, my mom and her boyfriend of three years. My father had just started dating his third girlfriend, but I only saw them every other weekend and on special occasions. He wasnt exactly a hands-on parent, and after they split up, he became even less involved in our lives. I was going with a guy friend to winter formal, and was trying on my heels when my moms boyfriend came in and jokingly reminded me that I didnt know how to dance. He patiently led me step-by-step through a waltz as I stumbled around in my heels. Thats when it hit me that somebody doesnt have to be your father to be your dad, and that you dont have to be directly related to someone for … Continue reading

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Indiana University launches $300 million precision health initiative – Healthcare IT News

Posted: Published on May 11th, 2017

Indiana Universitys first Grand Challenge initiative, Precision Health, has recruited Kun Huang to serve as director of data sciences and informatics for the $300 million, five-year research project, which was first announced in June 2016. Huang is a professor of biomedical informatics at the Ohio State University, where he also serves as associate dean for genome informatics in the College of Medicine and director of the Division of Computational Biology and Bioinformatics. He will join IU on July 17. [Also:The dawn of precision medicine has begun, ONC says] Huang is recognized internationally for his work in bioinformatics and computing He has focused his research on translational bioinformatics and integrative genomics tools for precision health, algorithms and software employed to visualize large and complex biomedical data, computer vision, machine learning, medical imaging and computational biology. In addition to his role as director of data sciences and informatics for the Precision Health Initiative. At IU, Huang will lead the development of innovative informatics solutions as part of the universitys Precision Health Initiative, which is focused on patient-centered precision medicine therapies. He also will serve as chair in genomic data sciences for the Precision Health Initiative and as assistant dean for data sciences, … Continue reading

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This Grey's Anatomy Teaser Hints at [SPOILER]'s Exit – TV Guide (blog)

Posted: Published on May 11th, 2017

Now Playing 9 Things You Didn't Know About Grey's Anatomy It's been rumored for months that actress Jerrika Hinton might be taking leave of Grey Sloan Memorial Hospital sometime this season, and the newest teaser for Grey's Anatomy's upcoming episode certainly paints a grim picture for her very near future on the show. Hinton, who's played Dr. Stephanie Edwards since the series' ninth season, is the focus of this clip from TVLine, which shows the halls of the hospital swarming with police as Chief Bailey (Chandra Wilson) frantically searches for Edwards while Jackson Avery (Jesse Williams) laments his decision to leave Edwards with the apparently dangerous patient she's shown wheeling around. When it was first reported that Hinton might be leaving Grey's, the news was that she wouldn't return as a series regular, leaving open the possibility of her still coming in as a guest star. However, if this teaser is any indication, her departure might just be more final than anyone expected ... which wouldn't be too much of a surprise, given how murder-happy the Grey's writers have been with their medical staff over the years. Hinton is expected to star in Wes Ball's new HBO dramedy series, Here, … Continue reading

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Two companies work to demystify surgical procedures and anatomy … – MobiHealthNews

Posted: Published on May 11th, 2017

Even the tiniest view of a surgical procedure can be too much for non-medical professionals, but for actual surgeons, more visibility is a real asset. But there is only so much to be seen with the naked eye, so medical navigation technology and mixed reality company Scopis has launched a new tool to give surgeons enhanced visibility when performing spinal surgery. By merging the capabilities of Microsoft HoloLens with their surgical navigation platform, Berlin, Germany and Cambridge, Massachusetts-based Scopis has developed the Holographic Navigation Platform. By donning a pair of the HoloLens glasses, surgeons can see a 3D overlay of the pre-planned positioning of screws, allowing the surgeon to interactively align their instruments with the holographic visualization and find the proper location more quickly. Additionally, surgeons can keep their eye on the operative field, and they can also used gestures to place virtual monitors onto their visual field. Scopis Holographic Navigation Platform is a universal solution that offers specific advantages for spinal surgeries and can also be applied in the many other areas where the highest levels of precision and speed are critical. In neurosurgery, for example, brain tumors could be located faster and with higher accuracy, Scopis CEO and … Continue reading

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'Grey's Anatomy' Finale Has 'Amazing Cliffhanger' Before 'Spectacular' Season 14 – Moviefone

Posted: Published on May 11th, 2017

The "Grey's Anatomy" Season 13 finale will be "very on fire." Literally? We'll see. Episode 24, "Ring of Fire" (hint, hint?) airs Thursday, May 18 with this synopsis: "The doctors' lives are at risk after a dangerous patient escapes the hospital room. Alex must make a hard choice in his relationship with Jo while Meredith has some big news for Nathan that brings things to a turning point." Executive producer Debbie Allen (Catherine Avery) directed the finale, and she told Entertainment Weekly, "There's actually two events going on at the same time that are pretty big that affect the entire hospital community. You should be worried. There's cause for worry. There's an amazing cliffhanger that will have everybody thinking, 'Wow, where is this going?!'" She added that they'll "plant more seeds that fuel the fire for what is going to happen next season." Allen added, in a separate EW interview, "I think Season 14 is going to be spectacular. We're planting some seeds that you won't see coming, but you will be waiting to see how it's all going to play out." Show creator Shonda Rhimes is the one who teased, to EW, "Debbie Allen and I like to say … Continue reading

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Cerebral palsy SDR surgery call for Wales – BBC News

Posted: Published on May 10th, 2017

BBC News Cerebral palsy SDR surgery call for Wales BBC News Dr Sue Hurrell, who set up the charity Support 4 SDR Wales after her daughter had the treatment, said the surgery was not suitable for everyone. "A lot of people have complex cerebral palsy with different types of movement problems and it will only ... and more » See the rest here: Cerebral palsy SDR surgery call for Wales - BBC News … Continue reading

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Bipolar Drug May Treat Traumatic Brain Injuries – Drug Discovery & Development

Posted: Published on May 10th, 2017

A drug used to treat bipolar disorder and other forms of depression may help to preserve brain function and prevent nerve cells from dying in people with a traumatic brain injury, according to a new Rutgers University study. In research published inScientific Reports, Rutgers scientists discovered that lithium - used as a mood stabilizer and to treat depression and bipolar disorder - and rapamycin, a treatment for some forms of cancer, protected nerve cells in the brain and stopped the chemical glutamate from sending signals to other cells and creating further brain cell damage. "Many medications now used for those suffering with traumatic brain injury focus on treating the symptoms and stopping the pain instead of protecting any further damage from occurring," said lead author Bonnie Firestein, professor in the Department of Cell Biology and Neuroscience in the School of Arts and Sciences at Rutgers University-New Brunswick. "We wanted to find a drug that could protect the cells and keep them from dying." According to the Centers for Disease Control and Prevention, traumatic brain injury (TBI) is a major cause of death and disability in the United States with an estimated 1.7 million people sustaining a TBI annually. About 30 … Continue reading

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