The quest to cure multiple sclerosis, or even to discover its cause, has remained elusive. But in March, the U.S. Food and Drug Administration approved a new drug to treat the most severe form of the disabling neurologic condition, which causes the bodys immune system to malfunction, attacking the cells of the spinal cord and brain.MS affects more than 450,000 people more often women in the United States. The new drug, Ocrevus, has been hailed by researchers and physicians as a game-changer, with the potential to lead to new avenues of treatment for other diseases, as well. One of those involved in the research and development of the drug is neurologist and scientist Amit Bar-Or, recently named chief of the multiple sclerosis division in the University of Pennsylvanias Department of Neurology, and director of the new Center for Neuroinflammation and Experimental Neurotherapeutics. He spoke to us recently about the new MS treatment, and why even those of us who weren't science majors will find this tale of T cells, B cells and a molecule called CD20 fascinating. Let's start with a brief overview of Ocrevus and how it works. Ocrevus is an example of an anti-CD20 monoclonal antibody. Basically, it … Continue reading
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