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First Drug To Treat Aggressive MS Hits The Market | WLRN – WLRN

Posted: Published on April 18th, 2017

The first drug to treat an aggressive form of multiple sclerosis has hit the market. Click here to listen to an excerpt from the conversation. The FDA approved the drug, sold as Ocrevus, two weeks ago. The approval comes after a series of clinical trials across the nation, including at the University of South Floridas Multiple Sclerosis Center in Tampa. Health News Floridas Stephanie Colombini talked with Dr. Janice Maldonado, Assistant Professor of Neurology at the center to learn more about Ocrevus and its development. Heres some highlights from their conversation: MALDONADO: Multiple sclerosis has two different presentations in which [Ocrevus] was tested. The relapsing form of MS is the form in which patients will have events that take away neurologic function, meaning transient times where they lose function in a limb, their vision, etc. The drug was tested in patients with the relapsing form of MS; and in the other form of MS, which is less common, it occurs in 10-15% of the MS population, and thats the primary-progressive form of MS. In primary-progressive MS, a patient will start to have a neurologic problem, and it does not get better ever; it accumulates overtime, it progresses. COLOMBINI: What were … Continue reading →

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Vietnam’s trans community relies on the black market for hormones – Gay Star News

Posted: Published on April 18th, 2017

Facebook An estimated 270,000 transgender people can now change their gender marker in Vietnam. Many of Vietnams trans communityare turning to the black market to buy hormone medication. Hormone replacement therapy and gender reassignment surgery are not legal in Vietnam. Many trans people have resorted to buying bootlegged drugs from neighbouring Thailand. Huynh Nha An, 21, self-prescribes and injects hormones to stop her facial hair growing back. Every month she must decide whether she will spend her minimum wage on hormones or food. She relies on advice from her friends about how much medication she should take and how often. When I dont use hormones regularly I turn back into a boy, Im no longer smooth like a girl, she told the AFP. In 2015, Vietnam updated its laws to recognise the true gender of peoplewho had undergone gender reassignment surgery. But the surgery is still banned in the country, so many travel abroad to have it. For 10 years twins, Truc Lam and Truc Linh have taken multiple morning-after pills everyday in the hope theyll grow breasts. The right hormones for their transition are easier to come by now. But they hope the law will soon change in Vietnam. … Continue reading →

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Science vs all-natural: Which is better for hot flushes? | Starts at 60 – Starts at 60

Posted: Published on April 18th, 2017

If you see a female friend or colleague sitting in front of a desk fan in winter while everyone else is shivering in sweaters, chances are she is having a hot flush, courtesy of the menopause. Hot flushes and night sweats are the most common symptoms of the female reproductive milestone. The menopause is often blamed for a host of other symptoms such as insomnia, joint pains, depression and mood swings, vaginal dryness and difficulty concentrating. Hot flushes can last for years and be debilitating, and conventional treatments such as hormone replacement therapy (HRT) and antidepressants come with risks. HRT increases the chance of developing potentially deadly clots in the leg veins; a small increase in breast cancer risk has also been reported. Because of these risks, women may turn to herbal products that are purportedly safer and have fewer side effects. A native American root called black cohosh (Actaea racemosa) is included in many such treatments used for hot flushes. The root has a long history of use in Europe and became popular around the world after receiving German approval as a non-prescription drug for hot flushes in 2000. In Australia, it is sold in various formulations and promoted … Continue reading →

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Cincinnati native hurt in pool party accident accepted into stem cell research study – WLWT Cincinnati

Posted: Published on April 18th, 2017

CINCINNATI An Elder High School grad who was critically injured has been accepted into a stem cell research study at Rush University in Chicago, his family reported. Ryan Custer, a Wright State University freshman, was injured during a pool party near Miami University earlier this month. He suffered a traumatic head injury, fracturing his vertebrae and sending him to the intensive care unit at the University of Cincinnati Medical Center. Family and friends said he's undergone multiple surgeries on his spine, was put on a breathing tube and has had a tracheotomy performed. As of Tuesday, he was talking and breathing on his own for a few hours at a time, and feeling had returned to his feet. Custer will leave for Chicago to participate in the study as soon as he is able, his family said. A GoFundMe page has been set up to help Ryan Custer and his family during this difficult time. Read more from the original source: Cincinnati native hurt in pool party accident accepted into stem cell research study - WLWT Cincinnati … Continue reading →

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Protein primes mouse stem cells to quickly repair injury, study finds – Medical Xpress

Posted: Published on April 18th, 2017

April 18, 2017 Credit: martha sexton/public domain Like drag car racers revving their engines at the starting line, stem cells respond more quickly to injury when they've been previously primed with one dose of a single protein, according to a study from the Stanford University School of Medicine. Mice given the priming protein recover muscle function more quickly after damage, their skin heals more rapidly and even the shaved area around the injury regrows hair more quickly, the study found. Harnessing the power of this protein may one day help people recover more quickly from surgery or restore youthful vigor to aging stem cells. "We're trying to better understand wound healing in response to trauma and aging," said Thomas Rando, MD, PhD, professor of neurology and neurological sciences. "We've shown that muscle and bone marrow stem cells enter a stage of alertness in response to distant injury that allows them to spring into action more quickly. Now we've pinpointed the protein responsible for priming them to do what they do better and faster." Rando, who also directs Stanford's Glenn Center for the Biology of Aging, is the senior author of the study, which will be published April 18 in Cell … Continue reading →

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'Grey's Anatomy,' 'Scandal' Producer Doubles Down on Progressivism – NewsBusters (blog)

Posted: Published on April 18th, 2017

'Grey's Anatomy,' 'Scandal' Producer Doubles Down on Progressivism NewsBusters (blog) As most readers may know by now, one of the biggest Trump-haters in Hollywood is television producer Shonda Rhimes, a fanatical progressive who has ... Scoop: GREY'S ANATOMY on ABC - Thursday, May 4, 2017Broadway World The Tulane Hullabaloo : Queue: Bingeing blessings The Tulane ...Tulane Hullabaloo all 4 news articles » Follow this link: 'Grey's Anatomy,' 'Scandal' Producer Doubles Down on Progressivism - NewsBusters (blog) … Continue reading →

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Anatomy of a Lynching – The New York Times – New York Times

Posted: Published on April 18th, 2017

New York Times Anatomy of a Lynching - The New York Times New York Times NEW DELHI A lynching is much more than just a murder. A murder may occur in private. A lynching is a public spectacle; it demands an audience. and more » Here is the original post: Anatomy of a Lynching - The New York Times - New York Times … Continue reading →

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Anatomy of a Goal: Ola Kamara's Equalizer – Massive Report – Massive Report

Posted: Published on April 18th, 2017

Welcome to the Anatomy of a Goal, where each week we dissect one goal (or near goal) from the previous weeks Columbus Crew SC match. For Week 7 on the 2017 MLS Season, we take a look at Ola Kamaras 37th minute tap-in goal that put Crew SC level with Toronto FC at 1-1, as part of the 2-1 win on Saturday. Heres a look at the finish from the Columbus striker. In the 20th minute, Jozy Altidore put Toronto in the lead with a headed goal off a Victor Vazquez corner kick. Toronto controlled much of the first 37 minutes, but Columbus begun to settle down and get back into this match. Kamaras equalizing goal begins with a TFC throw in. Toronto left center-back Justin Morrow had three options in the above photo: center midfielder Michael Bradley, left midfielder Raheem Edwards, and center midfielder Armando Cooper. An unmarked Bradley was probably the best option, but Morrow instead opted to make a short throw to Cooper. Morrows throw barely reached Cooper, who was easily dispossessed by Crew SC winger Niko Hansen. Above, notice that Crew SC attacking midfielder Federico Higuain is moving ahead of Morrow even before Hansen receives the … Continue reading →

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Anatomy of a Disney musical: Composer reveals process of creating iconic songs – ABC Online

Posted: Published on April 18th, 2017

Posted April 17, 2017 14:25:39 You probably don't know Alan Menken's name, but you do know his songs. The acclaimed composer and songwriter is the hidden face behind some of Disney's most iconic musicals, including Beauty and the Beast, The Little Mermaid and Aladdin. His body of work has earned him eight Oscars and 16 Golden Globes, and he's not done yet. Mr Menken is currently in Australia for the premiere of the stage musical of Aladdin and will head home soon to work on the upcoming live action film version of the story. So how does he create a Disney song? And what is the process for bringing a fledgling idea all the way to the big screen? The first thing to know is that for most Disney animations the musical dramatists aka the songwriters are brought in by the studio first. "That's something people don't know," Mr Menken told ABC News Breakfast. "Disney will say, 'We want to tell this story' and then we say, 'OK, how do we do it?'. "Generally you go from the basic story, to the basic structure of telling the story, to what musical style you're going to use to tell the story … Continue reading →

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Puma Biotechnology Announces FDA Advisory Committee to Review Neratinib for the Extended Adjuvant Treatment of … – Business Wire (press release)

Posted: Published on April 17th, 2017

LOS ANGELES, Calif.--(BUSINESS WIRE)--Puma Biotechnology, Inc. (Nasdaq: PBYI), a biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has scheduled the New Drug Application (NDA) for neratinib for discussion by the Oncologic Drugs Advisory Committee (ODAC) on May 24, 2017. Neratinib is an investigational therapy for the extended adjuvant treatment of early stage HER2-positive breast cancer that has previously been treated with a trastuzumab containing regimen. ODAC is an independent panel of experts that evaluates data concerning the efficacy and safety of marketed and investigational products for use in the treatment of cancer and makes appropriate recommendations to the FDA. Although the FDA will consider the recommendation of the panel, the final decision regarding the approval of the product is made by the FDA solely, and the recommendations by the panel are non-binding. Puma Biotechnology announced on September 20, 2016 that the FDA had accepted for filing the NDA for neratinib. The NDA for neratinib is based on results from both the Phase III ExteNET trial in extended adjuvant early stage HER2-positive breast cancer and the Phase II CONTROL trial in extended adjuvant early stage HER2-positive breast cancer. About Puma Biotechnology Puma Biotechnology, Inc. is a biopharmaceutical … Continue reading →

Posted in Biotechnology | Comments Off on Puma Biotechnology Announces FDA Advisory Committee to Review Neratinib for the Extended Adjuvant Treatment of … – Business Wire (press release)

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