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8 facts an endocrinologist wants you to know – TheHealthSite

Posted: Published on April 14th, 2017

Dr Sanjay Kalra enlightens us on 8 facts that you should know While hormones are the sneaky monsters which can be blamed for anything and everything; right from weight gain to crazy hunger, acne and hair loss, it is only a specialized endocrinologist who can help you diagnose a hormonal condition. Three most common diseases you can have in case of hormonal imbalance is diabetes, thyroid problems and osteoporosis. But an endocrinologist is the one who also specializes in infertility, menopause and hypertension. Dr Sanjay Kalra, Consultant Endocrinologist Bharti Hospital Karnal, Vice President South Asian Federation of Endocrine Societies, enlightens us on 8 facts that you should know: 1.Theres a risk in taking Human growth hormone without a doctors prescription: The pituitary gland is a structure in our brain that produces different types of specialized hormones, including growth hormone (also referred to as human growth hormone or HGH). In case of a deficiency, doctors may prescribe a synthetic growth hormone to help children reach their full height. This type of therapy is administered before a childs bone growth plates have fused or joined. Once the growth plates have fused, growth hormone should not be given as that might be harmful … Continue reading →

Posted in Hormone Replacement Therapy | Comments Off on 8 facts an endocrinologist wants you to know – TheHealthSite

Brain tissue from a petri dish: Stem cell research — ScienceDaily – Science Daily

Posted: Published on April 14th, 2017

The most complex organ in humans is the brain. Due to its complexity and, of course, for ethical reasons, it is extremely difficult to do scientific experiments on it -- ones that could help us to understand neurodegenerative diseases like Parkinson's, for example. Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have now succeeded in turning human stem cells derived from skin samples into tiny, three-dimensional, brain-like cultures that behave very similarly to cells in the human midbrain. In the researchers' petri dishes, different cell types develop, connect into a network, exchange signals and produce metabolic products typical of the active brain. "Our cell cultures open new doors to brain research," says Prof. Dr. Jens Schwamborn, in whose LCSB research group Developmental & Cellular Biology the research work was done. "We can now use them to study the causes of Parkinson's disease and how it could possibly be effectively treated." The team publishes its results today in the scientific journal Stem Cell Reports. The human midbrain is of particular interest to Parkinson's researchers: it is the seat of the tissue structure known medically as the substantia nigra. Here, nerve cells -- specifically dopaminergic neurons … Continue reading →

Posted in Stem Cell Research | Comments Off on Brain tissue from a petri dish: Stem cell research — ScienceDaily – Science Daily

How Medical Research Is Boosting Connecticut’s Economy – Yale News

Posted: Published on April 14th, 2017

by Kathleen Raven April 13, 2017 Jason Thomson, a core lab manager at the Yale Stem Cell Center, rebounded after large pharmaceutical companies retrenched in Connecticut. Photo credit: Robert Lisak Six years ago, Jason Thomson learned that his 13-year position in research at Pfizer would come to an end. He was among 1,100 employees laid off at the companys drug development laboratory in Groton. He feared that his career was in jeopardy. He didnt want to move his family and worried he wouldnt be able to land a comparable job in Connecticut. But things worked out much better than he expected. I was fortunate, says Thomson, a resident of Colchester. I was out of work for just over six months. Today, hes a lab manager at the Yale Stem Cell Center in New Haven. He plays a key role at the center, overseeing the preparation of stem cells that other researchers use to pursue their studies. Thomsons personal journey illustrates an economic shift in Connecticut. Over the past decade, several large pharmaceutical companies have either closed their doors here or cut hundreds of jobs from their local payrolls. These moves pose a threat to the state economy. For Connecticut to … Continue reading →

Posted in Stem Cell Research | Comments Off on How Medical Research Is Boosting Connecticut’s Economy – Yale News

Van, wheelchair stolen while teen gets treatment – KARE

Posted: Published on April 12th, 2017

KARE 9:00 PM. CDT April 12, 2017 James Bostic was getting treatment for cerebral palsy symptoms in Minnesota when his van and wheelchair were stolen back in Boston. (Photo: Courtesy GoFundMe.com) BOSTON - Police in Boston are investigating after a 17-year-old's van and wheelchair were stolen while he was getting treatment in Minnesota. James Bostichas cerebral palsy. In November, he and his mother traveled to Gillette Children's Hospital in Minnesota for what they thought would be a short trip to get some treatment for his symptoms. Their visit turned into a five-month stay, and they're now ready to return home - but they've discovered that they've been victims of a theft while they were away. James' mother, Beth, called Franciscan Children's Hospital in Boston to check on the van, with a wheelchair inside, that they left parked there. That's when she found out it was missing. Insurance will cover the rest of the vehicle loan on the van, but the Bosticscan't afford to replace the van or the wheelchair. The total cost could reach $60,000. The community has set up a GoFundMe page to help the Bostics. 2017 KARE-TV Read the rest here: Van, wheelchair stolen while teen gets treatment … Continue reading →

Posted in Cerebral Palsy Treatment | Comments Off on Van, wheelchair stolen while teen gets treatment – KARE

Will Mieville-Hawkins’ thanks Ilminster for raising 10,000 for brain … – Chard & Ilminster News

Posted: Published on April 12th, 2017

AN ILMINSTER man who suffered a life-changing brain injury after a tragic car crash has thanked the public after they raised more than 10,000 to help him get treatment. Will Mieville-Hawkins NHS treatment was stopped in March and members of the public have since rallied round to raise thousands of pounds to help, including a stranger who ran in the Taunton Marathon for him. Will, 26, of Station Road, was involved in a car crash on A303 in April 2016 in which he sustained a life-changing brain injury. He said: I suffered a big brain injury but I am not sure of the actual details. It left me unable to walk and unable to use one of my arms. Will was in a coma for a month and also lost his memory from the crash until July. The latest fundraiser to support Will is Bonnie Bow-Thompson of Bradford on Tone, who ran the Taunton Half-Marathon on April 2, raising more than 500 to help Will pay for his latest treatment. I didnt know her at all and I had never met her before, Will said. I felt incredibly overwhelmed when I found out. I met her for the first time … Continue reading →

Posted in Brain Injury Treatment | Comments Off on Will Mieville-Hawkins’ thanks Ilminster for raising 10,000 for brain … – Chard & Ilminster News

Nasal spray may limit brain damage from seizures – Futurity: Research News

Posted: Published on April 12th, 2017

A nasal spray can limit damage to the brain from a seizure disorder called status epilepticus, a study in animals shows. The disorder can present itself as a single seizure that lasts longer than 30 minutes or a series of seizures between which the person doesnt regain consciousness. If it doesnt stop quickly, even one episode can cause brain damage, loss of cognitive function, and memory loss. Saving the brain from injury and disease is certainly one of the holy grails of medicine. Saving the brain from injury and disease is certainly one of the holy grails of medicine, says Darwin J. Prockop, chair in genomic medicine and professor at the Texas A&M College of Medicine and co-senior author of the paper in the Proceedings of the National Academy of Sciences. Our paper suggests one way that this might be done, and not by a procedure that requires brain surgery or even injection into a vein: All that would be required is a nasal spray that a patient might receive in a doctors office. The compound in the nasal spray is anti-inflammatory exosomes, or extracellular vesicles, which Prockop and his team isolated from cultures of mesenchymal stem cells, a type … Continue reading →

Posted in Brain Injury Treatment | Comments Off on Nasal spray may limit brain damage from seizures – Futurity: Research News

New FDA Approved Treatment For MS Is Being Called A ‘Game Changer’ – CBS Philly

Posted: Published on April 12th, 2017

April 12, 2017 5:59 PM By Stephanie Stahl PHILADELPHIA (CBS) Multiple sclerosis affects about 400,000 people in the U.S. causing numbness, vision problems, pain and mobility issues. This new MS treatment comes with a hefty price $65,000 a year. It will be on the market in the next two weeks. Mike Miller was diagnosed with multiple sclerosis almost 10 years ago. It started with changes in his vision. It took a few years, and I went numb from the waist down, said Miller. He is one of the first patients in the country to receive the new FDA approved drug called Ocrevus. The drug treats relapsing MS, which is the most common form and also primary progressive MS, a severe form of the disease. This is first drug ever approved for that. We use words like, game changer,' said Dr. Aaron Boster with Ohio health Riverside Hospital. Mulitiple sclerosis happens when the immune system attacks and damages the central nervous system. The new drug targets an immune cell involved in the disease. It ends up massively decreasing how often people have MS attacks, massively decreasing the new spots that form on the brain, and slowing down the progression of their … Continue reading →

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Caligor to Support Puma Biotechnology’s Expanded Access … – Yahoo Finance

Posted: Published on April 12th, 2017

SECAUCUS, N.J.--(BUSINESS WIRE)-- Caligor Opco LLC, which specializes in early access to medicines and drug life-cycle management, today announced that it will provide regulatory and logistical management for Puma Biotechnologys (PBYI) expanded access program (EAP) for its investigational breast cancer therapy, PB272 (neratinib), in the United States. The U.S. Food and Drug Administration (FDA) permits expanded access to investigational drugs for treatment use for patients with serious or immediately life-threatening diseases or conditions who do not otherwise qualify for participation in a clinical trial and lack satisfactory therapeutic alternatives. The EAP will provide access to neratinib for the treatment of early stage HER2-positive breast cancer (extended adjuvant setting), HER2-positive metastatic breast cancer and HER2-mutated solid tumors. Patients must not be able to participate in any ongoing neratinib clinical trial to qualify for the EAP. Caligor also is providing regulatory, logistical, and supply chain support for Pumas Managed Access Program for neratinib outside the United States. We are gratified by the trust and confidence Puma has placed in us, said Tammy Bishop, Caligors Chief Commercial Officer. Within the past year, the FDA has introduced a streamlined application process and new guidance designed to improve its expanded access programs, and those initiatives … Continue reading →

Posted in Biotechnology | Comments Off on Caligor to Support Puma Biotechnology’s Expanded Access … – Yahoo Finance

Nature Biotechnology Features ReadCoor as a 2016 Leading Spinout – PR Newswire (press release)

Posted: Published on April 12th, 2017

CAMBRIDGE, Mass., April 12, 2017 /PRNewswire/ --ReadCoor, Inc. today announced that an article appearing in the April 2017 issue of Nature Biotechnology named the company among the 10 leading academic spinouts for 2016. Each year the journal identifies and features companies originating from academic institutions who have generated significant initial funding and who in the editors' assessment have demonstrated novel, potentially disruptive technology. In the words of the journal, "We believe these [ventures] represent some of the best science coming out of academia in 2016." "It is a tremendous honor to be included in this group of amazing technologies and companies," said Shawn Marcell, ReadCoor co-founder and CEO. "The team at ReadCoor is excited to deliver on the promise this revolutionary platform holds." The ReadCoor platform, called FISSEQ Fluorescent In-Situ Sequencing is the first application of in-situ spatial sequencing. ReadCoor was founded in 2014 by Richard Terry and George Church at the Harvard Wyss Institute, to bring Fluorescent In-Situ Sequencing into mainstream research use. Several key applications are being advanced including pathogen detection under a grant provided by the Bill & Melinda Gates Foundation, brain mapping or neural connectomics funded by IARPA, and drug development in areas such as central … Continue reading →

Posted in Biotechnology | Comments Off on Nature Biotechnology Features ReadCoor as a 2016 Leading Spinout – PR Newswire (press release)

How to color a lizard: From biology to mathematics – Science Daily

Posted: Published on April 12th, 2017

From the clown fish to leopards, skin colour patterns in animals arise from microscopic interactions among coloured cells that obey equations discovered by the mathematician Alan Turing. Today, researchers at the University of Geneva (UNIGE), Switzerland, and SIB Swiss Institute of Bioinformatics report in the journal Nature that a southwestern European lizard slowly acquires its intricate adult skin colour by changing the colour of individual skin scales using an esoteric computational system invented in 1948 by another mathematician: John von Neumann. The Swiss team shows that the 3D geometry of the lizard's skin scales causes the Turing mechanism to transform into the von Neumann computing system, allowing biology-driven research to link, for the first time, the work of these two mathematical giants. A multidisciplinary team of biologists, physicists and computer scientists lead by Michel Milinkovitch, professor at the Department of Genetics and Evolution of the UNIGE Faculty of Science, Switzerland and Group Leader at the SIB Swiss Institute of Bioinformatics, realised that the brown juvenile ocellated lizard (Timon lepidus) gradually transforms its skin colour as it ages to reach an intricate adult labyrinthine pattern where each scale is either green or black. This observation is at odd with the mechanism, … Continue reading →

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