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Diagnostic approach for veterans suffering hearing impairment and … – Medical Xpress

Posted: Published on March 17th, 2017

March 17, 2017 by Emil Venere This graphic details the effects of a blast shock wave. Credit: ProPublica, Al Granberg New research findings suggest mild blast trauma suffered by military personnel affects portions of the auditory system that have not been extensively studied after injuries occur, and this impairment might be diagnosed using well-established testing methods. "Advances in military protective equipment have increased the survival rate of personnel exposed to blasts, permitting exposure to higher intensity shock waves," said Riyi Shi (pronounced Ree Shee), a professor of neuroscience and biomedical engineering in Purdue University's Department of Basic Medical Sciences, College of Veterinary Medicine and Weldon School of Biomedical Engineering. "Due to increased blast survivability, new organ systems have emerged as vulnerable to blast trauma, particularly the brain and auditory system. The vast majority of victims suffer what we refer to as mild blast injury, which is asymptomatic and difficult to detect, yet can produce lasting hearing impairment and may be associated with additional damage to the brain." For U.S. military veterans with service-connected disabilities, the two most prevalent conditions are tinnitus, or ringing in the ear, and hearing loss. Researchers are using various tests based on the electrophysiology of the … Continue reading

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One stem cell treatment stabilizes macular degeneration, another blinds 3 patients – CNN

Posted: Published on March 17th, 2017

The macula is the spot in the center of your eye's retina. When that tissue begins to thin and break down, this is referred to as macular degeneration, a blurring of the sharp central vision necessary for driving, reading and other close-up work. Most people develop this disease as they age. For the latest study, researchers led by Dr. Michiko Mandai of the laboratory for retinal regeneration at RIKEN Center for Developmental Biology in Japan tested an experimental stem cell treatment on a 77-year-old woman diagnosed with "wet," or neovascular age-related, macular degeneration. The "wet" form of the disease involves blood vessels positioned underneath the pigment epithelium (a layer of retinal cells) growing through the epithelium and harming the eye's photoreceptor cells. In Japan, wet age-related macular degeneration is the most common form, but in Caucasian populations, only about 10% of people with age-related macular degeneration gets that form. The "dry" form involves the macula breaking down without growth of blood vessels where they're not supposed to be. To stop the progress of wet macular degeneration, the researchers performed surgery to transplant a sheet of retinal pigment epithelial cells under the retina in one of the patient's eye. The transplanted … Continue reading

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Strategy shift: Stem cell research uses donor cells to cut tumor risks – Genetic Literacy Project

Posted: Published on March 17th, 2017

Scientists can create [induced pluripotent stem (iPS) cells] from any cell in the body. [But while they]can be reprogrammed to become any type of cell, from skin to liver to nerve cells,[iPS cells] can also give rise to potentially dangerous mutations, possibly including ones that lead to cancerous tumors. Thus, iPS cells are a double-edged swordBut now Japanese researchers are trying a different approach. When Kyoto University researcher Shinya Yamanaka announced in 2006 that his lab had created iPS cells from mouse skin cells for the first time, biologists were stunnedA decade after the Yamanaka teams groundbreaking discoveries, however, iPS cells have retreated from the headlines. All eyes, however, are back on Kobe City Medical Center General Hospital, which is resuming its retina trialthis time with iPS cells from donors instead of cells from patients themselves.Using the Cell Research and Application (CiRA)s bank of iPS cells, there are significant time and cost savingsit could be one fifth the cost of cell preparation and patient transplant or less. Regenerative medicine and drug discovery are the two key applications for iPS cells, Yamanaka says. With the use of iPS cell stock, we are now able to work quicker and cheaper, so thats … Continue reading

Posted in Stem Cell Research | Comments Off on Strategy shift: Stem cell research uses donor cells to cut tumor risks – Genetic Literacy Project

Transform 815: Xue Jun-Li’s stem cell research in Rockford sheds light on motor neuron diseases – Rockford Register Star

Posted: Published on March 17th, 2017

By Isaac GuererroStaff writer Xue-Jun Li spends her days studying motor neurons, the cells that send signals from the brain to the body's voluntary muscles. Motor neuron diseases are degenerative, which means that the muscles don't stop working all at once. When the motor neurons begin to fail, one slowly loses control of the arms and legs, the ability to swallow and, eventually, to breathe. Scientists know very little about the human nervous system and what causes the motor neurons to stop functioning. Li has published more than 37 peer-reviewed manuscripts and has developed human stem cell models for spastic paraplegias and spinal muscular atrophy, which is the leading genetic cause of death for infants. Li joined the University of Illinois College of Medicine at Rockford as an associate professor in the Biomedical Sciences Department last May. Her research is supported by the National Institute of Health and ALS Association, among others. I love the satisfaction of new discoveries, new ideas you get from working in the lab, the interaction with students, she said. But any breakthrough you make is a collaboration. Her stem cell research is concerned with, among other things, an attempt to better understand microtubule defects that … Continue reading

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Two more retractions for stem cell researcher appealing her dismissal – Retraction Watch (blog)

Posted: Published on March 17th, 2017

Susana Gonzalez Susana Gonzalez, a rising star in stem cell research, has had a rough year. In addition to being fired from her former research institute (which she is now appealing), one of her grants (totaling nearly 2 million Euros) was suspended. Most recently, she has received two new retractions in Nature Communications over figure duplications and missing raw data. By our count, she has a total of three retractions. Both of the new noticessay the papers contained figures duplicated in other papers by Gonzalez, and neither includes Gonzalez among the list of co-authors who agreed to the retraction. Gonzalez was dismissed from her position at the National Center for Cardiovascular Research (CNIC) in Spain last February over allegations of misconduct. According to the head of basic research at CNIC, Gonzalez is still embroiled in a legal battle with the Centerover her dismissal. Vicente Andrscould not go into detail because of the ongoinglitigation, but he told us: I can only confirm that the court has decided in favor of CNIC and upheld the sacking of Dr. Gonzalez, but the decision is not final and is being appealed. The legal proceedings appear to have prompted Gonzalezs first retractionof a 2012 paper, … Continue reading

Posted in Stem Cell Research | Comments Off on Two more retractions for stem cell researcher appealing her dismissal – Retraction Watch (blog)

Ceramics artist inspired by nature, biotechnology – Jewish News of Greater Phoenix

Posted: Published on March 17th, 2017

Ceramist Susan Beiners work has been exhibited in China, France, the Netherlands and across the nation, but it took some persuading to get her to exhibit her creations at Temple Solels latest Art Showcase. After some cajoling, Beiner relented and now her earlier work is on display at Temple Solel through May 31. A reception and talk featuring Beiner are scheduled for 10:30 a.m. Sunday, April 2, at Temple Solel, 6805 E. McDonald Drive, Paradise Valley. Your current subscription does not provide access to this content. Please click the button below to manage your account. kAmp %6>A=6 $@=6= >6>36C D:?46 a_`b[ q6:?6C 😀 2? 2DD@4:2E6 AC@76DD@C 2E pC:K@?2 $E2E6 &?:G6CD:EJD[ w6C36C86C r@==686 @7 u:?6 pCE] w6C 96D:E2?4J E@ D9@H 96C H@C< 2E $@=6= 42>6 7C@> E96 724ED E92E D96 925 ?6G6C 4@?D:56C65 5:DA=2J:?8 96C 2CE 😕 2 DJ?28@8F6 367@C6[ 2D H6== 2D E96 =2C86 D:K6 @7 96C =2E6DE 4C62E:@?D]k^Am kAm(6 E@=5 $FD2? D96 H2D 2 EC6>6?5@FD C6D@FC46 2?5 2 A2CE @7 E96 E6>A=6 2?5 H6 H2?E65 E@ D66 96C H@C2D[ 2 >6>36C @7 E96 pCE o $@=6= 4@>>:EE66] %9:D 😀 E96 7:CDE E:>6 H6G6 925 2 46C2>:4:DE]k^Am kAmx?DA:C65 3J E96 4C27ED >@G6>6?E[ q6:?6C 3682? 4C62E:?8 9:89=J 56E2:=65[ 2?5 2E E:>6D … Continue reading

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College hires leader for Biotechnology Center of Excellence – Triad Business Journal

Posted: Published on March 17th, 2017

Triad Business Journal College hires leader for Biotechnology Center of Excellence Triad Business Journal Our Biotechnology Center of Excellence will be key to Alamance County's economic development and we are excited to have an administrator with the depth and breadth of experience as Yonnie Butler, said President Algie Gatewood. His range of ... Original post: College hires leader for Biotechnology Center of Excellence - Triad Business Journal … Continue reading

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Why Should Investors Consider An Allocation In Speculative Biotechnology: A Sector Analysis – Seeking Alpha

Posted: Published on March 17th, 2017

Many intriguing articles have been written about investing in biotechnology. Biotechnology investment has been referenced by many knowledgeable and respectable authors as controversial, out of favor, and even sexy (this article by Stephen Simpson, CFA, is must read). Surviving current trends in biotechnology stock price manipulation can be both stressful and disappointing. This leaves us all to wonder is it even worth it to try speculative biotechnology as an investment option? StrongBio believes it is worth it, even if it results in losses that are hard to endure. In the end, contributions to healthcare from growing sources of capital are extremely important for improved patient care (termed supply-side capital). As these contributions have grown, however, so too has waste. With proper selection, timing, and diversification (three pillars of biotechnology investment), the common retail investor can eventually be financially rewarded as philanthropic goals of the population are met. Simply put, biotechnology companies focus on drug development aiming to treat an unmet or under-met disease or medical condition. Companies that have succeeded have net sales in the tens of billions and total market values in the hundreds of billions of dollars. Speculative biotechnology companies, in contrast, differ from proven top biotechnology companies … Continue reading

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Nasdaq Composite Index Approaches Record High as … – Economic Calendar

Posted: Published on March 17th, 2017

The Nasdaq Composite Index rose Wednesday, buoyed by broad advances at biotechnology and IT companies, after the Federal Reserve decided to raise interest rates for the second time in three meetings. The technology-heavy index rose 0.7% to 5,900.05, its fifth advance in the last six sessions. The benchmark index settled just below all-time highs. With the gain, the Nasdaq has returned nearly 10% for the year, outpacing the S&P 500 Index and Dow Jones Industrial Average. A total of 2,009 companies listed on the Nasdaq reported gains, versus 888 that finished lower and 229 that went unchanged. A total of 166 companies reported new highs, versus 47 that set new lows. Health stocks listed on the S&P 500 rose more than 1%, with pharmaceuticals, biotechnology and life sciences leading the rally. Information technology also advanced 0.6% as a sector. Advertising The Nasdaq Biotechnology Index rose 1.5% to 3,162.82. The Federal Reserve raised its benchmark interest rate by a quarter point to 1% in a move that was widely anticipated by the markets. Policymakers continue to expect three rate increases this year, putting the central bank on course for two additional adjustments in 2017. In terms of upcoming releases, the U.S. … Continue reading

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National Academies Report Finds Future Biotechnology Products … – The National Law Review

Posted: Published on March 17th, 2017

On March 9, 2017, the National Academies of Sciences, Engineering, and Medicine (National Academies) published a report entitled Preparing for Future Products of Biotechnology, prepared by the Committee on Future Biotechnology Products and Opportunities to Enhance Capabilities of the Biotechnology Regulatory System (Committee). The Committee was asked to describe the possible future products of biotechnology that will arise over the next five to ten years, as well as provide some insights that can help shape the capabilities within the U.S. Environmental Protection Agency (EPA), the U.S. Food and Drug Administration (FDA), and the U.S. Department of Agriculture (USDA) as they move forward. According to the Committee, agencies may be overwhelmed by the number and diversity of new biotechnology products. The Committee states that the agencies should increase their scientific capabilities, tools, and expertise in key areas of expected growth. The report reflects the Committees deliberations regarding the future products of biotechnology that are likely to appear on the horizon, the challenges that the regulatory agencies might face, and the opportunities for enhancing the regulatory system to prepare for what might be coming. The Committee reached consensus on conclusions and recommendations that are based on extensive information gathering, Committee discussions, and … Continue reading

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