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Longeveron Achieves Milestone in Groundbreaking Stem Cell Trial for Alzheimer’s Disease – PR Newswire (press release)

Posted: Published on March 15th, 2017

"The impact of Alzheimer's disease is vast, far exceeding the medical community's current ability to treat it," said Joshua M. Hare, M.D., Longeveron's Co-Founder and Chief Science Officer. "Regenerative medicine and cell-based therapies offer a promising new approach to close this gap and address the urgent need for effective therapies to combat the condition." An important component in the progression of Alzheimer's disease is neuroinflammation. Longeveron was recently awarded a $1 million Part the Cloud Challenge on Neuroinflammation grant from the Alzheimer's Association to help support this research. "Adult stem cells are very potent anti-inflammatories. The characteristic amyloid plaques found in the brains of Alzheimer's disease patients produce inflammation, and stem cells can reduce inflammation," explained Bernard S. Baumel, M.D., Principal Investigator for the trial. "Alzheimer's also impairs the brain's ability to adequately produce new brain cells in the memory area known as the hippocampus. Stem cells can stimulate the brain to produce these new cells needed to form memory. We believe that an infusion of LMSCs may improve the condition or at least halt the progression of the disease." Prior research shows that adult MSCs target and reduce inflammation, promote tissue repair and improve brain function in mouse models … Continue reading

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From skin to brain: Stem cells without genetic modification – Phys.Org

Posted: Published on March 15th, 2017

March 15, 2017 by Grove Potter The four images, from left to right, show Keratinocyte-derive neural crest stem cells turning into neurons as shown by typical neuronal morphology. Credit: University at Buffalo. A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain. The practical implications could be very significant, from studying genetic diseases in a dish to generating possible regenerative cures from the patient's own cells. "It's actually quite remarkable that it happens," says Stelios T. Andreadis, PhD, professor and chair of UB's Department of Chemical and Biological Engineering, who recently published a paper on the results in the journal Stem Cells. The identity of the cells was further confirmed by lineage tracing experiments, where the reprogrammed cells were implanted in chicken embryos and acted just as neural crest cells do. Stem cells have been derived from adult cells before, but not without adding genes to alter the cells. The new process yields neural crest … Continue reading

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Stem Cell Expert Opens California Office – PR Newswire (press release)

Posted: Published on March 15th, 2017

Dr. Lox has a keen interest in the management of not only arthritis in aging athletes, but helping patients keep higher levels of function and quality of life later in life. Dr. Lox has also helped patients in need and less fortunate from other countries where stem cells are not available. Often patients are unaware of the availability of stem cells in the United States. Contrary to popular notions, the Vatican supports stem cell research just not embryonic. Patients from Canada and the United Kingdom do not have access to stem cells in their countries, in part due to their national health care, many of these patients have treated with Dr. Lox. Every week Dr. Lox receives inquiries from around the world in reference to stem cells for knees, hips, shoulders, wrist, ankles, and a variety of other sports and arthritic problems. Dr. Lox may be reached at Drlox.com, at (310) 975-7033 and (727) 462-5582, or at info@drlox.com. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/stem-cell-expert-opens-california-office-300424186.html SOURCE Sports and Regenerative Medicine Centers Follow this link: Stem Cell Expert Opens California Office - PR Newswire (press release) … Continue reading

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Stem Cell Therapy – Runner’s World

Posted: Published on March 15th, 2017

Runner's World Stem Cell Therapy Runner's World While PRP therapy stimulates the healing process of tissue that is already there, stem cells may create new tissue. This is why researchers and physicians think this therapy may help joint injuries caused by worn-out cartilage; in cell cultures, stem ... Overview of Stem Cell Therapies Market Research Report Global Trends in the Competitive, Technological and R&D ...Medgadget (blog) all 19 news articles » See more here: Stem Cell Therapy - Runner's World … Continue reading

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Antibody Therapy Targets Cancer Stem Cells: Study – The Scientist

Posted: Published on March 15th, 2017

The Scientist Antibody Therapy Targets Cancer Stem Cells: Study The Scientist Carla Kim, an expert in stem cells, cancer, and lung biology at Harvard Medical School who was not involved in the study, acknowledged the importance of the research. One nice thing about this is that they're studying EGFR-mutant tumors, she said ... Cancer Cells Slayed by Vitamin CAnti Aging News Vitamin C can target cancer stem cellsThe Nation all 4 news articles » Original post: Antibody Therapy Targets Cancer Stem Cells: Study - The Scientist … Continue reading

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Seven Bridges Announces Scientific Advisory Board – Broadway World

Posted: Published on March 15th, 2017

Seven Bridges, the biomedical data analysis company, today announced its Scientific Advisory Board, which formalizes relationships with leading global experts in genomic medicine, bioinformatics and cancer research. Members of the Seven Bridges Scientific Advisory Board will advise on the companys product designs and strategies for cloud-based biomedical data analysis, as well as share their knowledge about key challenges and opportunities in the field of genomic research. The inaugural members of the Seven Bridges Scientific Advisory Board include: As we continue to build on Seven Bridges vision to connect the worlds biomedical data for better research and health, input from leaders in the fields of genetics, bioinformatics and cancer research will prove invaluable to our efforts, said Brandi Davis-Dusenbery, CEO of Seven Bridges. We are honored that these respected experts have agreed to participate in our SAB and look forward to working with them to constantly advance the state of the art in data analysis for our large-scale pharmaceutical and government clients. About Seven Bridges Seven Bridges is the biomedical data analysis company accelerating breakthroughs in genomics research for cancer, drug development and precision medicine. The scalable, cloud-based Seven Bridges Platform empowers rapid, collaborative analysis of millions of genomes in concert … Continue reading

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Pain in the neck: Engineers use CRISPR technology to prevent … – Science Daily

Posted: Published on March 15th, 2017

For millions of sufferers, there is nothing more debilitating than chronic back or joint pain. It can feel like a lifetime of misery. But researchers led by University of Utah bioengineering assistant professor Robby Bowles have discovered a way to curb chronic pain by modulating genes that reduce tissue- and cell-damaging inflammation. "This has applications for many inflammatory-driven diseases," Bowles says. "It could be applied for arthritis or to therapeutic cells that are being delivered to inflammatory environments that need to be protected from inflammation." The team's discovery was published in a new paper this month, "CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments," in a special issue of Tissue Engineering. University of Utah bioengineering doctoral student, Niloofar Farhang, co-authored the study, which is a collaborative project between the University of Utah, Duke University and Washington University in St. Louis. In chronic back pain, for example, slipped or herniated discs are a result of damaged tissue when inflammation causes cells to create molecules that break down tissue. Typically, inflammation is nature's way of alerting the immune system to repair tissue or tackle infection. But chronic inflammation can instead lead to … Continue reading

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U. scientists develop cell therapy for chronic disc pain – Deseret News

Posted: Published on March 15th, 2017

SALT LAKE CITY Relief for chronic back and neck pain may be on the horizon, thanks to emerging science technology under development at the University of Utah. Bioengineering researchers have discovered a technique to control chronic pain by regulating genes that reduce tissue- and cell-damaging inflammation. This has applications for many inflammatory-driven diseases, said assistant professor Robby Bowles, who led the research. It could be applied for arthritis or to therapeutic cells that are being delivered to inflammatory environments that need to be protected from inflammation. In laymens terms, the therapy has the potential to treat chronic pain by relieving swelling in affected areas and healing the tissue, he said. For instance, chronic pain in slipped or herniated discs result from damaged tissue when swelling causes cells to create molecules that break down tissue, he explained. Inflammation is natures way of alerting the immune system to repair tissue or fight infection, but chronic inflammation can lead to tissue degeneration and pain, he said. Bowles team uses the Clustered Regularly Interspaced Short Palindromic Repeat system known as CRISPR a new technology that modifies human genetics to halt cell death and keep cells from producing molecules that damage tissue and result in … Continue reading

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Graduate Programs on the Rise, US News Rankings Show – UC Merced University News

Posted: Published on March 15th, 2017

At just 12 years old, the graduate programs at the University of California, Merced, are already among the best in the nation, according to the U.S. News & World Reports 2018 Best Graduate Schoolsrankings. UC Merceds School of Engineering made its second appearance in the graduate school rankings, released today (March 14), rising to No. 127 in the nation after debuting at No. 140 in 2015. The school made an impressive debut in the environmental engineering rankings, placing No. 70 in the nation in that discipline. UC Merced also made a major jump in the psychology rankings, appearing at No. 90 in the nation after debuting at No. 158 in2015. In addition to the environmental engineering ranking, the campus was also ranked No. 135 in electrical engineering and was recognized for bioengineering and mechanical engineering. Only the top 75 in bioengineering and top 115 in mechanical engineering received numericalrankings. Dean Mark Matsumoto said the School of Engineerings ranking reflects the perception of a university that is quickly coming into itsown. This ranking is an indication of a maturing School of Engineering with an improving reputation, Matsumoto said. This milestone is due to the quality of the faculty and students we … Continue reading

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Anatomy – Tips and Advice for Studying

Posted: Published on March 15th, 2017

What Is Anatomy? Anatomy is the study of the structure of living organisms. This subdiscipline of biology can be further categorized into the study of large scale anatomical structures (gross anatomy) and the study of microscopic anatomical structures (microscopic anatomy). Human anatomy deals with anatomical structures of the human body, including cells, tissues, organs, and organ systems. Anatomy is always linked to physiology, the study of how biological processes function in living organisms. Therefore it is not enough to be able to identify a structure, its function must also be understood. The study of human anatomy gives us a better understanding of the structures of the body and how they work. When taking a basic anatomy course, your goal should be to learn and understand the structures and functions of the major body systems. It is important to remember that organ systems don't just exist as individual units. Each system depends on the others, either directly or indirectly, to keep the body functioning normally. It is also important to be able to identify the major cells, tissues, and organs being studied and to know how they function. Studying anatomy involves lots of memorization. For instance, the human body contains 206 … Continue reading

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