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'Grey's Anatomy' Star Ellen Pompeo Takes Fans Behind the Scenes of the Popular Show – Closer Weekly

Posted: Published on March 4th, 2017

Closer Weekly 'Grey's Anatomy' Star Ellen Pompeo Takes Fans Behind the Scenes of the Popular Show Closer Weekly Grey's Anatomy fans were stoked when the show's star Ellen Pompeo gave them a sneak-peek at her life on set. In the series of Instagram clips on Thursday, March 2, the 47-year-old actress gave a detailed behind-the-scenes look at the popular medical ... Continued here: 'Grey's Anatomy' Star Ellen Pompeo Takes Fans Behind the Scenes of the Popular Show - Closer Weekly … Continue reading →

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'Grey's Anatomy' Season 13 Sneak Peek: Jackson Threatens His Mother – Wetpaint

Posted: Published on March 4th, 2017

Credit: Richard Cartwright/ABC 2016 Disney | ABC Television Group. All rights reserved. Greys Anatomy Season 13s next new episode, airing Thursday, March 9, is Civil War an apt title, considering how harshly divided Eliza Minnick has made the hospital staff. As you might imagine, however, no one is being civil not even family members, as youll see in a new sneak peek featuring Jackson Avery and mom Catherine. To whet your appetite for the episode, heres ABCs synopsis: Richard, Jackson, April and Catherine tackle a grueling trauma case intensified by hospital politics. Amelia finally faces her feelings about Owen, and Meredith gets caught between Nathan and Alex over a patient. As the sneak peek starts, Jackson finds his mother as she heads to the pit, perhaps en route to that trauma case. I need to talk to you about this Minnick situation, he tells his mom. What situation? Catherine says. Shes doing great. (Shes playing coy, clearly!) Dont pretend you dont know what you did, Mom, Jackson says. People have been fighting this since the minute you brought her here. Bailey brought her here, Catherine contends. Shes certainly not saying shes the one who inspired the hire, but Jackson cuts … Continue reading →

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Scott Foley Has Been Hiding on 'Grey's Anatomy' For Five Years Now – Wetpaint

Posted: Published on March 4th, 2017

}rHo)te O]I,uP[4IHC=3con>svrn`}Y;;` p^au?~RakNQn?EQv&aO|c/ik4l]mMUR;kCnhhKEOEsp[mt J#N;6q,C98Gd;jN@"T0t5T;GQmtf^}*d=zlE0Hj? & }k}(j(xJhQ"x1crzA$ YxA}ISu[/ e-y/Pv`34?^vIeH?+Hq`Kld>|fV&fMGcOomM< F-Z-Nj`x 0YV@VzdVb^7 jw'qEAhVQK^6ZC-1:`g ,eAQ[2kZh8jNhXU}z s K=R/a[BRkqlHf4Z izMNFr HN n*jy$RIHID(Hb4 gG'~fl"583_&BIR#PW3lyd(Vh(Ty}K*3b/k:rF^T72%uX*v"aXGUYg#Xt:VX*,>Y7O%UfH,oi K+u{*~1%IlDLNZqpaHU0^,f.#`!Tr$uxzb>nZ;UE((1~c[lldRRbM @3Ic%!fL$[c%a>PJxfS&{+iRur*:+w(r|c5v2#H8OJ'FQEF%W${6Z7u?ZY?;{[8mw[,+,%/C6j *GT`6U|I`$fB hD!>N>umjbSH;J'nPq h%MTh(GP YFdjLPOE p*MKAQ B6$/kCS"}?TN!rmAq;11 6_)oO?m&Ma!k5R5g],6k9!ph6t%T=NOHNQ^d.@G@SUnBU'cK$/RU _w,CTN!kC#$Rk@q!j@7AM(b/CFVGY1iR./)$[_XOq:2HC-{|Ve!BPtyI(a@DK07wOs='SY ~h:0)w>SS)hFR!HdUjC.r_u:7'ChK(}8zi,PQ[z0ZXDV(J:# _SSknTEXFob&Yl5;6jQ(ZPd LzlWmUv]_eA6nK5F[+Q@xG9.i>g8r"u=[=3F~jg`/?_+{Wz}CkLx{/}Y{]s7?w5z=J_>//ANWGu{p? /GC,;8:6{@&)"&VP1aAtSku,{a,^n8m| 3e 6.U2=((K&~]oXpk*BAnl+5,K8Kf{DK}#kmhthLQ-H=C_84wptO4EUi_1bt7P.z=MLy7M`Q+@"G^t#S5D)NWDJ:C,!g$XU3#z#}pWM=vGCIMWmvt#],mXWK2m9a@"ead&gm !KlFls }f_8_Fgb4mg73l+' tN7FDo/p}`h``|DIEscwPBc 1E^):HtP~!| X~$ j$6$No$2Cm%T_"9F,-_L(k9 P>@s$pY9LmRMH;414Zu;D/E*V8DcJQPv*6Xbg$}uQnIDz)g&BO~q`_)rkA(A_I_r2X#c^ 0]G'mS%/`?2^;naUJF }=|](dG5B?ea4>{L,1z … Continue reading →

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The Anatomy of Black Money – The Indian Express

Posted: Published on March 4th, 2017

The Indian Express The Anatomy of Black Money The Indian Express Following Prime Minister Narendra Modi's demonetisation of Rs 500 and Rs 1,000 notes on November 8 last year, there has been a heightened interest in the phenomenon of black money, an issue with which we in India seem to be obsessively concerned. and more » Excerpt from: The Anatomy of Black Money - The Indian Express … Continue reading →

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New Eczema Drug Promising in Early Trial – WebMD

Posted: Published on March 3rd, 2017

Nemolizumab significantly reduced the itch and improved appearance of skin WebMD News from HealthDay By Steven Reinberg HealthDay Reporter THURSDAY, March 2, 2017 (HealthDay News) -- An experimental drug may significantly reduce the itching and improve the appearance of moderate to severe eczema, a new, preliminary trial finds. Nemolizumab is a man-made, injectable antibody that acts against the protein that has been identified as playing a part in eczema, the international team of researchers said. "The treatments for atopic dermatitis [eczema] have been disappointing because of their lack of efficacy and the long-term side effects," said Dr. Doris Day, a dermatologist at Lenox Hill Hospital in New York City. She had no role in the study. "There are also issues with compliance, since the products often need to be applied to broad areas multiple times a day," she added. Since this is a chronic condition, continued treatment is usually needed to maintain results, Day explained. "The goal is to find a non-steroid treatment that is easy to follow, and with reliable results and minimal adverse effects," she said. While the hope is always for a cure, the results of this trial "are encouraging and give hope to those suffering from … Continue reading →

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Stress During Pregnancy Linked To Eczema In Children – Huffington Post Canada

Posted: Published on March 3rd, 2017

New U.K. research suggests that stress before conception can increase the risk of eczema in children. Carried out by the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, the study is the first to link maternal stress before conception with the risk of atopic eczema in future children. For the research the study assessed the stress levels of women recruited to the Southampton Women's Survey before they were pregnant. Participants were asked to report how stressed they were in their daily lives with a sub-group also asked about their psychological wellbeing. Around 3,000 babies were born to women taking part in the survey, who were then assessed for eczema at the ages of six months and 12 months. The results showed that more than one in six women reported that stress affected their health 'quite a lot' or 'extremely' before falling pregnant, with the analysis showing that the infants of these mothers had a 20 per cent higher likelihood of developing atopic eczema at age 12 months when compared with the children of other participants. The results also suggested that stress and low mood experienced closer to the time of conception may have an even greater impact on eczema … Continue reading →

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EpiCast Report: Ulcerative Colitis – Epidemiology Forecast to 2025 – PR Newswire (press release)

Posted: Published on March 3rd, 2017

LONDON, March 2, 2017 /PRNewswire/ -- Summary Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by long-lasting inflammation and ulcers (sores) in the lining of the digestive tract. In UC, because of an abnormal response of the body's immune system, the lining of the colon becomes inflamed and develops tiny open sores, or ulcers, that produce pus and mucous. This causes abdominal discomfort and frequent emptying of the colon. There is no cure for UC except surgical removal of the colon, but medications can help curb the inflammatory response and symptoms. UC commonly affects teenagers and young adults, and can result in poor development and growth; nonetheless, the disease can also occur in children and older individuals. In the 7MM, GlobalData epidemiologists forecast that the diagnosed incident cases of UC will increase from 86,509 cases in 2015 to 95,864 cases in 2025, at an annual growth rate (AGR) of 1.08%. The US will have the highest number of diagnosed incident cases of UC over the forecast period, while Spain will have the lowest. In the 7MM, GlobalData epidemiologists forecast that the diagnosed prevalent cases of UC will increase from 1,628,113 cases in 2015 to 1,711,603 cases in 2025, … Continue reading →

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Often the villain, fructose may play hero’s role in muscular dystrophy treatment – Medical Xpress

Posted: Published on March 3rd, 2017

March 3, 2017 A substance widely known as a villain for its role in causing obesity-related health problems has emerged as a possible hero in the fight against a debilitating genetic disorder. Research suggests that fructose, a sugar found in honey, fruits and vegetables, makes a type of molecular treatment for Duchenne muscular dystrophy more effective. Progressive muscle degeneration and weakness characterize Duchenne muscular dystrophy, which is caused by the absence of a protein, dystrophin, that helps keep muscles intact. Symptoms usually appear around age 4, first affecting the shoulders, upper arms, hips and thighs. Patients have a hard time rising from the floor, climbing stairs, keeping their balance and raising their arms. Ultimately, they require use of a wheelchair, and most die in their 30s when their cardiac and respiratory systems fail. Duchenne primarily affects males, and about one boy in 3,500 will be born with it. Hong Moulton of the Oregon State University College of Veterinary Medicine was part of an international collaboration that looked at fructose's ability to enhance the uptake and activity of antisense oligonucleotides, or AOs. Therapy with those molecules has been shown to restore some production of dystrophin, but efficiently delivering the molecules to … Continue reading →

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aTyr Pharma Receives EMA Orphan Drug Designation for the Treatment of Limb Girdle Muscular Dystrophy with … – PR Newswire (press release)

Posted: Published on March 3rd, 2017

EMA orphan designation is intended to encourage development of medicines for the diagnosis, treatment, or prevention of life-threatening or chronically debilitating conditions that affect no more than 5 in 10,000 people in the EU. Medicines that receive orphan designation are eligible for a number of incentives, including assistance with development of the medicine; reduced fees for marketing-authorization applications; and extended market exclusivity once the medicine is authorized. Orphan designation is conferred following a positive opinion by the EMA's Committee for Orphan Medicinal Products (COMP). About Resolaris aTyr Pharma is developing Resolaris as a potential first-in-class intravenous protein therapeutic for the treatment of rare myopathies with an immune component. Resolaris is derived from a naturally occurring protein released by human skeletal muscle cells. aTyr believes Resolaris has the potential to provide therapeutic benefit to patients with rare myopathies with an immune component characterized by excessive immune cell involvement. About LGMD2B Limb girdle muscular dystrophy (LGMD) refers to a group of rare genetic myopathies, of which there are more than 20 different subtypes, none with approved therapies. LGMD affects an estimated 16,000 patients in the U.S., approximately 3,000 of whom have LGMD2B. LGMD2B is a recessive genetic disease caused by a toxic … Continue reading →

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Nerve growth factor delivery by ultrasound-mediated nanobubble destruction as a treatment for acute spinal cord … – Dove Medical Press

Posted: Published on March 3rd, 2017

Back to Browse Journals International Journal of Nanomedicine Volume 12 Zhaojun Song,1 Zhigang Wang,2 Jieliang Shen,1 Shengxi Xu,1 Zhenming Hu1 1Department of Orthopedics, The First Affiliated Hospital, 2Institution of Ultrasound Imaging, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, Peoples Republic of China Background: Spinal cord injuries (SCIs) can cause severe disability or death. Treatment options include surgical intervention, drug therapy, and stem cell transplantation. However, the efficacy of these methods for functional recovery remains unsatisfactory. Purpose: This study was conducted to explore the effect of ultrasound (US)-mediated destruction of poly(lactic-co-glycolic acid) (PLGA) nanobubbles (NBs) expressing nerve growth factor (NGF) (NGF/PLGA NBs) on nerve regeneration in rats following SCI. Materials and methods: Adult male Sprague Dawley rats were randomly divided into four treatment groups after Allen hit models of SCI were established. The groups were normal saline (NS) group, NGF and NBs group, NGF and US group, and NGF/PLGA NBs and US group. Histological changes after SCI were observed by hematoxylin and eosin staining. Neuron viability was determined by Nissl staining. Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling staining was used to examine cell apoptosis. NGF gene and protein expressions were detected by quantitative reverse transcription polymerase chain reaction and … Continue reading →

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