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Breakthrough in MS treatment – HealthCanal.com (press release) (blog)

Posted: Published on February 13th, 2017

In separate clinical trials, a drug called ocrelizumab has been shown to reduce new attacks in patients with relapsing remitting multiple sclerosis (MS), and new symptom progression in primary progressive MS. Three studies conducted by an international team of researchers, which included Amit Bar-Or and Douglas Arnold from the Montreal Neurological Institute and Hospital of McGill University, have discovered that ocrelizumab can significantly reduce new attacks in patients with relapsing MS, as well as slow the progression of symptoms caused by primary progressive MS. In one study, 732 patients with primary progressive MS were randomized on a 2:1 ratio to receive either ocrelizumab, a humanized monoclonal antibody that depletes CD20+ B cells, or a placebo. The proportion of patients with 12-week confirmed disability progression was 39.3 per cent with the placebo versus 32.9 per cent with ocrelizumab. After 24 weeks, the proportion with confirmed disability progression was 35.7 per cent with placebo versus 29.6 per cent with ocrelizumab. By week 120, timed 25-foot walk worsened by 55.1 per cent for placebo versus 38.9 per cent for ocrelizumab. Patients given ocrelizumab were also found to have fewer new brain lesions and less brain volume loss than those given the placebo. Researchers … Continue reading

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Red Deer woman said MS treatment in Mexico helped her – Red Deer Advocate (subscription)

Posted: Published on February 13th, 2017

Heather Leblanc when she was being treated in Mexico for multiple sclerosis. She underwent chemotherapy before her stem cells were taken and then put back into her body. She posted a video diary of her experience online while she was there. A Red Deer woman who went to Mexico for treatment to try and stop the progression of multiple sclerosis said the experience was worth it. I feel a million times better, Heather Leblanc said on Monday. Leblanc, 37, had previously undergone different out-of-Canada treatments twice before, but she said the latest treatment known as HSCT (Hematopoietic stem cell transplantation). Her family covered most of the US $54,500 cost of the treatment in Monterrey, Mexico. Medical staff harvested some of her stem cells and then she had chemotherapy to break down her immune system. Then the healthy stem cells were re-introduced into her body to rebuild that immune system. She was there for a month late last year, returning home to her husband and two young children in early December. Her mother went with her to Mexico. MS people experience a brain fog where they dont think clearly, and I would say that has lifted, she said. Her energy has … Continue reading

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Ovarian hormones awaken newly discovered breast stem cells – Science Daily

Posted: Published on February 13th, 2017

Science Daily Ovarian hormones awaken newly discovered breast stem cells Science Daily The discovery was made by Dr Nai Yang Fu, Dr Anne Rios, Professor Jane Visvader and Professor Geoff Lindeman as part of a 20-year research program into how the breast develops from stem cells, and how breast cancers can arise from stem cells and ... Stem cell linked to breast cancer foundTVNZ Melbourne scientists' breast cell study offers cancer treatment hopeHerald Sun all 5 news articles » Read more: Ovarian hormones awaken newly discovered breast stem cells - Science Daily … Continue reading

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Study implicates neural stem cell defects in smooth brain syndrome – Medical Xpress

Posted: Published on February 13th, 2017

February 13, 2017 by Nicholas Weiler Research led by scientists at UC San Francisco and Case Western Reserve University School of Medicine has used brain "organoids"tiny 3-D models of human organs that scientists grow in a dish to study diseaseto identify root causes of Miller-Dieker Syndrome (MDS), a rare genetic disorder that causes fatal brain malformations. MDS is caused by a deletion of a section of human chromosome 17 containing genes important for neural development. The result is a brain whose outer layer, the neocortex, which is normally folded and furrowed to fit more brain into a limited skull, instead has a smooth appearance (lissencephaly) and is often smaller than normal (microcephaly). The disease is accompanied by severe seizures and intellectual disabilities, and few infants born with MDS survive beyond childhood. In the new studypublished online January 19, 2017 in Cell Stem Cellthe research team transformed skin cells from MDS patients and normal adults into induced pluripotent stem cells (IPSCs) and then into neural stem cells, which they placed in a 3 dimensional culture system to grow organoid models of the human neocortex with and without the genetic defect that causes MDS. Closely observing the development of these MDS organoids … Continue reading

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The New ABCs of Medical School: Anatomy, Biochemistry, and Cooking – Food Tank (blog)

Posted: Published on February 12th, 2017

As Hippocrates, the founder of modern medicine, spoke, Let food be thy medicine. However, most medical schools in the United States do not adequately teach nutrition. Several programs, including at Tulane University, are addressing this shortcoming by including cooking classes in their curriculum. The hope is that by teaching future doctors how to cook delicious and healthy meals, they will pass that knowledge on to their patients, improving long-term health. The rates of obesity and obesity-related diseases are increasing throughout the world according to Prediabetes: A Worldwide Epidemic. The Center for Disease Control reports that nearly half of all deaths in the United States are due to heart attacks, strokes, and diabetes. Entire scientific journals, such as Nutrition and Health, Diabetes, and the Journal of Nutrition, are devoted to examining the relationships between nutrition and health. Research has shown that nutrition is one of the leading causes of and significantly affects the management of diabetes, cardiovascular disease, and aging-related diseases. There is no clear correlation between policy recommendations and nutrition choices. For example, a study that provided nutrition information to adults at fast-food chains found that simply providing information did not alter consumer choices. Coaching has consistently proven effective at … Continue reading

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Style anatomy with Pinky Durrani – The Express Tribune

Posted: Published on February 12th, 2017

The artist, graphic designer, and now creative head of the clothing line Pinx, talks to us about her style evolution The artist, graphic designer, and now the creative head of the clothing line Pinx, talks to us about her style evolution. Having developed a passion for fashion from a very young age, she breaks down her signature look and her beloved fusion style statements Understanding your body is the key to looking good and a trait found amongst all impeccably dressed fashionistas. While people shy away from talking about their bodies, these brave souls explain how they work their anatomies to their advantage How would you describe your body type? I would say Im curvy and sporty. Has your body type changed over the last five years? Absolutely, and for the better! I feel a more positive and healthier change in my body. How has your style changed over the years? Its more fusion now, and a lot more versatile. I tend to wear tunics, which can easily blend with both Eastern and Western ensembles. I prefer that to wearing a typical shalwar kameez. In your opinion what is your most troublesome area? Definitely my arms they have always been … Continue reading

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This Breakthrough In Biotech Has Enormous Investment Potential – Forbes

Posted: Published on February 12th, 2017

Forbes This Breakthrough In Biotech Has Enormous Investment Potential Forbes Asterias Biotherapeutics (AST) continues to generate excitement and buzz around its stem cell treatment for catastrophic spinal cord injury (SCI). I wrote about this historic event back in September. That's when the company first released results about ... Visit link: This Breakthrough In Biotech Has Enormous Investment Potential - Forbes … Continue reading

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Treatments for Parkinson’s Disease | University of …

Posted: Published on February 12th, 2017

To make an appointment with a Parkinson's disease specialist, call 410-328-4323. Only in the last 30 years have dramatic breakthroughs been made in the management of Parkinson's disease. Current treatment can significantly relieve people's symptoms and markedly improve their quality of life. Treatment for Parkinson's disease may include any or all of the following: Meet our Parkinson's Disease Team The first stage of treatment for Parkinson's is an accurate diagnosis. This is tricky, as we have noted, particularly early in the disorder when distinguishing Parkinson's disease from other diseases with similar symptoms is particularly difficult. It may be helpful to see a neurologist who is experienced with what are called movement disorders. A movement disorder specialist has expertise in diagnosing and treating Parkinson's disease and related disorders. A visit to a movement disorder center may also be useful. Most such centers are connected with a department of neurology at a medical school, although some are freestanding clinics. The centers have access to appropriate rehabilitation facilities and are usually involved in research studies. The Maryland Parkinson's Disease and Movement Disorders Center is such a center. For more information about the University Physicians Consultation and Referral Service, please call 1-800-492-5538 (patients) or … Continue reading

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Cruel thieves steal charity box for nine-year-old girl raising money for operation so she can walk again – Mirror.co.uk

Posted: Published on February 12th, 2017

Callous thieves stole a charity box being used to raise money to pay for a nine-year-old to have an operation so she can walk again. The family of little Kareena Hayes need 10,000 to fund private treatment for the youngster, who suffers from cerebral palsy . Doctors have told the schoolgirl it is unlikely she will ever walk unaided again unless she has the surgery . The Marmalade and Tea cafe in Derbyshire has been raising money for the disabled youngster in a charity box on its counter. But cruel thieves smashed their way into the cafe and stole money from the till as well as the charity box - and even took a photo of Kareena that was attached to it. Now Kareena has launched an appeal for the money to be returned. She said: "I'm very angry and upset. I'm poorly and cannot walk well and they would have known that money was for me. How could they? "I'm really nervous for the treatment and we really need the money. For someone to take it is terrible. "I try and get on with my life as best I can. This is just terrible. I don't understand why anybody … Continue reading

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Newborn rats get mature hearts by serving as stem cell laboratory … – RT

Posted: Published on February 12th, 2017

When it comes to treating heart disease, researchers are hoping that stem cells could prove to be a breakthrough. When immature heart muscle cells were implanted into newborn rats, mature adult cells developed, a new study has found. Researchers at the Johns Hopkins University School of Medicine successfully injected about 200,000 immature heart muscle cells developed from mouse embryonic stem cells into the lower heart chamber of newborn rats that were engineered without an immune system for their bodies to accept the introduced foreign cells. Within a month, the cells began to appear as adult heart muscle cells, according to the study, which was recently published in Cell Reports. Chulan Kwon, leader of the study and member of the Johns Hopkins University School of Medicines Institute for Cell Engineering, said his team's research could represent a key advancement in the study and treatment of heart disease. "Our concept of using a live animal host to enable maturation of cardiomyocytes can be expanded to other areas of stem cell research and really opens up a new avenue to getting stem cells to mature,"said Kwon. Read more Kwon and his research group turned to newborn rats after realizing that cells grown in … Continue reading

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