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Experimental Stem Cell Therapy Stops Multiple Sclerosis In Its … – Vocativ

Posted: Published on February 6th, 2017

The prognosis for people affected by multiple sclerosis (MS), a degenerative autoimmune disorder that decimates the central nervous system, is a bleak one. The disease oftenbegins with a sudden burst of neurological symptoms like muscle spasms, vision problems, and trouble walking, then progresses differently, depending on which form of MS someone has. But eventually, nearly everyone with the disease comesto the point of being unable to move, breathe, or live independently. And sufferers on average live anywhere from five to ten years less than the general public. Currently, the best medications we have available do little more than slow MS down, or tamp down peoples symptoms. But an experimental therapy continues to provide the first glimmers of something ground-breaking an actual way to stop one form of the disease in its tracks, and maybe even reverse some of the damage already done. In this months Neurology, researchers detailed the final five-year-old results of a small clinical trial called HALT-MS. Twenty-four volunteers with MS who hadnt responded to conventional drugs were first given a powerful form of chemotherapy, high-dose immunosuppressive therapy (HDIT), that wiped out their immune system. Then they were given a transplant of their own stem cells taken out … Continue reading

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Australian transgender teens wanting hormone therapy up 360% – Gay Star News

Posted: Published on February 6th, 2017

Georgie Stone, Australia's leading transgender voice The number of Australian teenagers applying to start hormone replacement therapy (HRT) has jumped by 360%. In Australia people under the age of 18 must seek permission from the Family Court to begin HRT. The number of applications to the Family Court rose from five in 2013 to 23 in 2016. Sydneys Inner City Legal Centre (ICLC) provides support to families going through the court process. I think it is because there is so much more awareness of transgender issues in the media we have kids and their parents that are identifying exactly with that, ICLC principal, Hilary Kincaid, told The Daily Telegraph newspaper. Australia is the only country that requires transgender minors to getcourt approval for hormone treatment. The court process can costs families tens of thousands of dollars and can be traumatic. In 2016 activism around the issue gained traction as families and groups lobbied to parliamentarians to change the law. Teenager Georgie Stone gained national media attention with her story and led the campaign to change the requirement to get Family Court approval for minors to start HRT. She went on to be named LGBTI Person of the Year at the … Continue reading

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Can hormones affect heart health in women? – Las Vegas Sun

Posted: Published on February 6th, 2017

Monday, Feb. 6, 2017 | 2 a.m. The American Heart Association (AHA) estimates that 44 million women in the U.S. are affected by cardiovascular diseases, and when combined with stroke, these diseases kill an average of 1 woman every 80 seconds. Thats 1 in 3 female deaths annually, said Vanessa Gastwirth, MD, FACC, at MountainView Hospital. While historically considered a mens disease, heart disease kills more women than men every year. Furthermore, the AHA reports that 90 percent of all women have at least one risk factor for heart disease or stroke. Common risk factors include age, poor diet, sedentary lifestyle, smoking, genetics and, for some women, hormone levels. Estrogen can affect your cholesterol levels Naturally occurring estrogen tends to raise HDL cholesterol levels the good cholesterol that helps carry away artery-clogging LDL cholesterol. As such, women generally have more HDL cholesterol than men. When estrogen levels peak for women during childbearing years, this HDL provides an extra level of protection from developing heart disease earlier in life. Estrogen has favorable effects on health, including an improvement in cholesterol and on the function of blood vessel lining. However, it has adverse side effects as well, such as causing changes in … Continue reading

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Some Pregnant Women Should Be Treated for Subclinical Hypothyroidism – EndocrineWeb

Posted: Published on February 6th, 2017

Women treated for subclinical hypothyroidism (SCH) during pregnancy are less likely to experience pregnancy loss, a new study shows, but they face a greater risk of complications such as preterm delivery, gestational diabetes and pre-eclampsia.1 While the new research doesnt settle the ongoing controversy surrounding the question of whether pregnant women with SCH should receive thyroid-hormone replacement therapy, it may help identify the point at which treatment tips toward overall benefit and away from risk. Continuing to offer thyroid hormone treatment to decrease the risk of pregnancy loss is reasonable for women with TSH concentrations of 4.1-10.0 mIU/L, said the studys lead author, Spyridoula Maraka, M.D., a research collaborator with Mayo Clinic and assistant professor at the University of Arkansas for Medical Sciences and the Central Arkansas Veterans Health Care System. However, given the smaller magnitude of effect in women with lower TSH levels of 2.5-4.0 mIU/L, and in light of the possible increased risk of other adverse events, treatment may need to be withheld in this group. Indeed, given the findings of their study, published in The BMJ, Maraka and her co-authors have expressed concern that pregnant women whose levels of thyroid stimulating hormone (TSH) measure in the 2.5-4.0 … Continue reading

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Men: Stand up and protect yourself from the risk of osteoporosis … – Harvard Health

Posted: Published on February 6th, 2017

By Matthew Solan Executive Editor, Harvard Men's Health Watch Don't think men need to worry about osteoporosis? Think again. Older men have a greater risk of osteoporosis-related fractures than of getting prostate cancer. In fact, about one in four men older than 50 will break a bone due to osteoporosis during their lifetime, according to the National Osteoporosis Foundation. How can men protect themselves and lower their risk of osteoporosis? Here are some strategies: Studies have shown that low calcium intake is associated with low bone mass and higher fracture rates. Vitamin D is needed to help absorb calcium in the body, so you need adequate amounts of each. The Institute of Medicine's recommendations for adults include 1,000 milligrams (mg) per day of calcium until age 50 and 1,200 mg per day afterward, and 600 international unites (IU) daily of vitamin D until age 70 and then 800 IU afterwards. Some of the best sources of calcium include tofu, spinach, greens (collard, turnip, mustard, and kale), and dairy products like yogurt, cheese, and milk. High amounts of vitamin D are found in salmon, sardines, tuna, milk, and mushrooms. If you have a deficiency, or have trouble consuming these foods, you … Continue reading

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California’s stem cell program ponders a future of new challenges and old promises – Los Angeles Times

Posted: Published on February 6th, 2017

Evangelina Padilla Vaccaro of Coronais the new face of stem cell science in California. Born with bubble baby disease that deprived her of a functioning immune system, she was cured with stem cell therapy developed in Donald Kohns lab at UCLA, which has received millions of dollars in grants from the California stem cell program. Now shes a vivacious 4-year-old, depictedastride a hobby horse and clad in a pink sweatshirt bearing a lightning bolton the programs 2016 annual report under the legend CURED. Thank you all for the amazing work you do, her father told the program board during its Dec. 13 meeting. Evangelina represents the great potential of the $3-billion state program, formally known as the California Institute for Regenerative Medicine, or CIRM, but also its dilemma as it ponders its next chapter. Established in 2004 by a nearly 60-40 vote for Proposition 71, CIRM began issuing grants in 2006. Now, after 10 years, the program has committed $2.2 billion of its bond-funded war chest. Its expecting to spend the rest by the end of 2020. So it wont be long before CIRM must confront the question of whether to fold up shop when its well runs dry, seek … Continue reading

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Hype versus hope: Deciphering news about stem cell breakthroughs – Genetic Literacy Project

Posted: Published on February 6th, 2017

For many people suffering from disabling conditions, such as Parkinsons disease, spinal injury and paralysis, heart disease, and even cancer, announcements in the press around breakthroughs in stem cell research undoubtedly bring hope. Keeping the balance between hope and hype is a difficult one, particularly when there are vulnerable and suffering people relying on the hope medical research offers. As Australian of the Year, Emeritus Professor Alan Mackay-Sim, stated in his acceptance speech, there are now many clinical trials being performed in Australia and around the globe, to determine whether the delivery of certain types of cells, including some grown from stem cells, into the spinal column can allow patients with spinal cord injury to regain function. For these individuals, even a small gain of functionis a major advance. However, as yet there is no stem cell silver bullet. And stem cells that have shown promise can also cause complications. It was also reported a paraplegic woman developed a growth in her spine many years after an unsuccessful spinal stem cell treatmentHence, more research to test these and other types of cells in well-run clinical trials is required to move from anecdote to safe and effective therapies. The GLP aggregated … Continue reading

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Stem Cell Day of Discovery introduces students to USC scientists – USC News

Posted: Published on February 6th, 2017

You can be anything you want just like a stem cell. That was a key lesson for the 500 middle and high school students at the USC Stem Cell Day of Discovery on USCs Health Sciences Campus. It was a true joy to welcome the middle and high school students from our neighboring communities in Boyle Heights, El Sereno, Lincoln Heights, the San Gabriel Valley and throughout Los Angeles, said Rohit Varma, dean of the Keck School of Medicine of USC. This bright young generation brings tremendous potential to their future pursuits in biotechnology and beyond. Hosted by USC Civic Engagement and USC Stem Cell, the Feb. 4 event introduced the students to stem cell scientists. Dont be shy, said Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC. Ask our scientists questions. Ask them about their science, but also ask them about their personal journeys that led to where they are. The students followed McMahons advice as they engaged in fun activities and lively conversations. They visited labs to get hands-on experience with microscopes and pipettes. They competed as contestants in a stem cell edition of Family Feud, viewed … Continue reading

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People are more willing to accept embryonic stem cell research than … – ZME Science

Posted: Published on February 6th, 2017

As stem cell research continues to be a very divisive topic, a new study has revealed that the general public is much more willing to accept it than politicians. Image in Public Domain. The Swiss are very liberal with their referendums they have quite a few every year. This offers a unique and direct perspective to see how voters think about a variety of topics including (in this case) embryonic stem cell research. They found that people were much more willing to accept the research than politicians. By analysing the outcomes of a referendum on a liberal new bill regulating such research, we reveal an about 10 percentage point lower conditional probability of the bill being accepted by politicians than by voters, the study reads. The motivations for the two categories of people are also quite different. For politicians, its all about the politics, whereas general people are swayed by different aspects. Whereas the behaviour of politicians is driven almost entirely by party affiliation, citizen votes are driven not only by party attachment but also by church attendance. If youve kept up with stem cell research, youre probably wondering why were talking about embryonic stem cell research (taking stem cells … Continue reading

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Chickscope 1.5: Explore: Embryology: Day 1 – The Journey …

Posted: Published on February 6th, 2017

Day 1: The Journey Begins The Egg Yolk An infertile and a fertile egg. Can you tell the difference? The white chalazae is much more prominent in the infertile egg. However there is no correlation between fertility and the size of the chalazae. The chalazae is composed of mucin fibers; mucin is a special kind of structural protein. The chalazae holds the yolk in place within the egg. In the infertile egg, on the left, the nucleus is merely a light spot on the yolk. The egg on the right is fertilized. In the fertilized egg the ovum has fused with a sperm to begin forming an embryo. By the time the fertilized egg is laid, many cells are divided on the surface of the yolk and formed a blastoderm. Can you see the difference between the nucleus of the infertile egg and the blastoderm of the fertilized egg? Both are indicated by the blue arrow. - Page 3 of 12 - Read more: Chickscope 1.5: Explore: Embryology: Day 1 - The Journey ... … Continue reading

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