Interspecies gene transfer occurs naturally; interspecies hybrids produced by sexual means can lead to new species with genetic components of both pre-existing species. Interspecies hybridization played an important role in the development of domesticated plants. Interspecies gene transfer occurs naturally; interspecies hybrids produced by sexual means can lead to new species with genetic components of both pre-existing species. Interspecies hybridization played an important role in the development of domesticated plants. Interspecies hybrids can also be produced artificiallly between sexually incompatible species. Cells of both plants and animals can be caused to fuse, producing viable hybrid cell-lines. Cultured hybrid plant cells can regenerate whole plants, so cell fusion allows crosses of sexually incompatible species. Most animal cells cannot regenerate whole individuals; however, the fusion of antibody-forming cells (which are difficult to culture) and "transformed" (cancer-like) cells, gives rise to immortal cell-lines, each producing one particular antibody, so-called monoclonal antibodies. These cell-lines can be used for the commercial production of diagnostic and antidisease antibody preparations. (Fusions involving human cells play a major role in investigations of human heredity and GENETIC DISEASE.) In nature, the transfer of genes between sexually incompatible species also occurs; for example, genes can be carried between species during … Continue reading
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