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Parkinson’s Disease Information Page: National Institute …

Posted: Published on July 12th, 2016

Parkinson's disease (PD) belongs to a group of conditions called motor system disorders, which are the result of the loss of dopamine-producing brain cells. The four primary symptoms of PD are tremor, or trembling in hands, arms, legs, jaw, and face; rigidity, or stiffness of the limbs and trunk; bradykinesia, or slowness of movement; and postural instability, or impaired balance and coordination. As these symptoms become more pronounced, patients may have difficulty walking, talking, or completing other simple tasks. PD usually affects people over the age of 60. Early symptoms of PD are subtle and occur gradually. In some people the disease progresses more quickly than in others. As the disease progresses, the shaking, or tremor, which affects the majority of people with PD may begin to interfere with daily activities. Other symptoms may include depression and other emotional changes; difficulty in swallowing, chewing, and speaking; urinary problems or constipation; skin problems; and sleep disruptions. There are currently no blood or laboratory tests that have been proven to help in diagnosing sporadic PD. Therefore the diagnosis is based on medical history and a neurological examination. The disease can be difficult to diagnose accurately. Doctors may sometimes request brain scans or … Continue reading →

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nanoDDS | 13th International Nanomedicine & Drug Delivery …

Posted: Published on July 12th, 2016

The Nanomedicine and Drug Delivery Symposium is the key annual event for researchers developing next-generation delivery vehicles targeted, responsive, biodegradable nanomaterials to make diagnostics more sensitive and drugs more effective In January 2003 Dr. Alexander Kabanov and Dr. Kazunori Kataoka have organized the first nanomedicine meeting in the United States The Nanomedicine and Drug Delivery Symposium (nanoDDS). Since then nanoDDS has been held annually in different locations across North America. Over years it has attracted over 2000 participants from 30 different countries and became one of the most authoritative forums in its field. Each year the meeting comes to a different University campus, thereby promoting knowledge and becoming a major world-class scientific event for its students and scholars. The objectives of nanoDDS are to 1) discuss groundbreaking discoveries and developments in nanomedicine and drug delivery; 2) highlight clinical developments and opportunities for advancing nanomedicine technology to the marketplace; and 3) engage and educate students, postdoctoral trainees and scientists from the local University and all over the world. See the rest here: nanoDDS | 13th International Nanomedicine & Drug Delivery ... … Continue reading →

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Stem Cells – Research | UC San Francisco

Posted: Published on July 12th, 2016

Since the success in 1998 by the University of Wisconsins James Thomson in deriving human embryonic stem cells from embryos, the stem cell research field has exploded. The discovery by Japans Shinya Yamanaka, MD, PhD,in 2006, of how to transform ordinary adult skin cells into cells that, like embryonic stem cells, are capable of developing into any cell in the human body, has revolutionized stem cell research. At top, Robert Blelloch, MD, PhD, performs stem cell research. Above,Shinya Yamanaka, MD, PhD, a scientist at the UCSF-affiliated Gladstone Institutes, UCSF and Kyoto University, was recognized for a revolutionary achievement in the field of stem cell science with a Nobel Prize in Medicine in 2012. In between and since, there has been major progress in scientists understanding of stem cells. Today, fueled in part by the robust research enterprise at UCSF, the field is burgeoning.Yamanaka, a senior investigator at the UCSF-affiliated Gladstone Institutes and a professor of anatomy at UCSF, shared the Nobel Prize in Physiology and Medicine with John B. Gurdon of the Gurdon Institute in Cambridge, England, in 2012. In about 125 labs of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF one … Continue reading →

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Institute for Stem Cell & Regenerative Medicine

Posted: Published on July 12th, 2016

ISCRM's Deok-Ho Kim, Assistant Professor in the Department of Bioengineering at University of Washington, has been named a 2015 Young Innovator of Cellular and Molecular Bioengineering (CMBE) by the Biomedical Engineering Society (BMES). Dr. Kim is one of only 11 distinguished honorees this year who are tenure-track assistant professors working in the field of cellular and molecular bioengineering. This years honorees represent some of the best and brightest working in the field and were chosen from a highly competitive pool of candidates, noted a CMBE official. As part of the selection process, they were invited to submit full-length manuscripts that underwent a rigorous peer-review process prior to publication in the most recent issue of the scientific journalCellular and Molecular Bioengineering. Dr. Kim was recognized for the development of a nanopatterned human induced pluripotent stem cell (iPSC)-derived model of a dystrophin-null cardiomyopathic phenotype. His research group has demonstrated the utility of bio-inspired nanotopographically-defined materials for controlling the structural and functional properties of hiPSC-derived cardiomyocytes, providing an enabling platform for effectively stratifying normal and structural cardiac disease phenotypes in vitro. This work was performed in collaboration with Dr. David Mack and Dr. Martin Childers in the Institute of Stem Cell and Regenerative … Continue reading →

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Stem Cell Research News Topix

Posted: Published on July 12th, 2016

Top Stories 27 min ago | ABC Triumph or Travesty, US-Iran Ties Warming Over Nuclear Deal 76 articles 1 hr ago | WSJ Hillary Clinton's Lead Over Bernie Sanders Widens 1 hr ago | ABC China Expected to Report Slower but Still Strong Growth 2 hrs ago | WaPo US Embassy says several Americans missing in Iraq 27 articles 2 hrs ago | CBS Bernie Sanders hammers Hillary Clinton over Wall Street ties 10 articles 2 hrs ago | CNN That time Bernie Sanders voted for Bill Clinton's plan to... 26 articles 2 hrs ago | ABC Race Tightens: Clinton, Sanders Clash on Guns, Health Care 53 articles 6 hrs ago | WaPo Seahawksa comeback salvages their dignity but not their S... 22 articles 14 hrs ago | ABC Synagogue Visit: Pope Denounces Violence Done in God's Name 16 hrs ago | WSJ Scores Killed in Islamic State Incursion in Eastern Syria Read more: Stem Cell Research News Topix … Continue reading →

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Treatments for Multiple Sclerosis

Posted: Published on July 12th, 2016

Treatments for Multiple Sclerosis The year 1993 saw the release of the first disease-modifying drug, Betaseron, for multiple sclerosis. By the turn of the century, three other disease-modifying drugs had also been approved. Now with more than 10 products are available, patients not only have treatments but treatment options. It is important to note that none of the currently approved disease-modifying agents are not a cure for MS. However, all of these products can alter the course of the disease by decreasing the number and severity of relapses, by slowing the progression of the disease, and by reducing the accumulation of new lesions. MS Treatment Guidelines Research demonstrates that potentially irreversible axonal damage may occur early in relapsing-remitting MS. These therapies appear to be more effective in preventing new lesions than in repairing old lesions. Based on these findings, it is the consensus of researchers and clinicians with expertise in MS that the following treatment guidelines be followed: Therapy with a disease-modifying drug should be initiated as early in the disease course as possible. Such treatment may also be considered for those who have experienced a first attack and are at high risk of developing MS. (This is known as … Continue reading →

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What are the treatments for muscular dystrophy?

Posted: Published on July 12th, 2016

No treatment is currently available to stop or reverse any form of muscular dystrophy (MD). Instead, certain therapies and medications aim to treat the various problems that result from MD and improve the quality of life for patients. These include the following1: Beginning physical therapy early can help keep muscles flexible and strong. A combination of physical activity and stretching exercises may be recommended. Many people with MD do not realize they have little respiratory strength until they have difficulty coughing or an infection leads to pneumonia. Regular visits to a specialist early in the diagnosis of MD can help guide treatment before a respiratory problem occurs2. Eventually, many MD patients require assisted ventilation. MD patients who experience weakness in the facial and throat muscles may benefit from learning to slow the pace of their speech by pausing more between breaths3 and by using special communication equipment. As physical abilities change, occupational therapy can help patients with MD relearn these movements and abilities. Occupational therapy also teaches patients to use assistive devices such as wheelchairs and utensils. At various times and depending on the form of MD, many patients require surgery to treat the conditions that result from MD. People … Continue reading →

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Epilepsy | Epilepsy Conference | Epilepsy Congress | Rome …

Posted: Published on July 12th, 2016

Epilepsy 2016 Omics InternationalConference Seriesprovides the perfect platform for global networking and we are truly delighted to invite you to attend our 2nd International Conference on Epilepsy and Treatment, during October 20-21, 2016 Rome, Italy. Epilepsy is a chronic disorder of the brain that affects people of all ages. More than 50 million people were affected worldwide. Synchronousbrain cellactivity causes seizuresanddepending onthe region of brain affectedthey willproducea rangeof behaviours. Track 1:Epilepsy Epilepsyis a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain. It is estimated that every year nearly 2.4 million people are diagnosed with Epilepsy and the population with active epilepsy is between 4 to10 per 1000 people. Nearly 80% of the individuals with epilepsy are found in developing regions. Historically, the epilepsy research has been under-funded. Annually NIH spends $30 billion for medical research, but of 1% is only spent onEpilepsy research. Of total medical costs Epilepsy alone results in an estimated annual cost of $15.5 billion. This session is an effort to address all areas related to Epilepsy and includes overview of Epilepsy in developing brain, Epileptogenesis, Genomics, Etiology and its Epidemiology, Translational … Continue reading →

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Cerebral Palsy Treatment – Healthline

Posted: Published on July 12th, 2016

What Is Cerebral Palsy? Cerebral palsy (CP) refers to a group of disorders that affect muscle movement and coordination. In many cases, vision, hearing, and sensation are also affected. The word cerebral means having to do with the brain. The word palsy means weakness or problems with body movement. CP is the most common cause of motor disabilities in childhood, affecting approximately 2 to 3 out of every 1,000 children. Abnormal brain development or injury to the developing brain can cause CP. The damage affects the part of the brain that controls body movement, coordination, and posture. It may occur before birth, during birth, or shortly after birth. Most children are born with CP, but they may not show symptoms of a disorder until months or years later.Symptoms usually appear before a child reaches age 3 or 4. The symptoms of CP vary from person-to-person. Some people with CP may have difficulty walking and sitting. Other people with CP can have trouble grasping objects. The symptoms can become more severe or less severe over time. People with CP can have other problems, such as: Theres no cure for CP, but early diagnosis and treatment can greatly improve quality of life. … Continue reading →

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Secondary Progressive MS: Symptoms and Treatment

Posted: Published on July 12th, 2016

People with secondary progressive multiple sclerosis (SPMS) start out with another type of MS -- relapsing-remitting multiple sclerosis. If you've been diagnosed with SPMS you may have had relapsing-remitting MS for a decade or more. That's when you may begin to feel a shift in your disease. The changes are often not easy to recognize. But you may notice that your relapses may not seem to fully go away. Most people with relapsing-remitting MS -- about 80% -- eventually get secondary progressive MS. The relapses and remissions that used to come and go change into symptoms that steadily get worse. The shift typically begins 15 to 20 years after youre first diagnosed with MS. Because multiple sclerosis is such a complex disease, it can be hard to spot the changes that signal SPMS, even for health professionals. Doctors often wait at least 6 months before they diagnose SPMS. Relapsing-remitting MS can be unpredictable, but theres usually a pattern of clear attacks followed by times of recovery. With SPMS, relapses tend to be less distinct. They may happen less often or not at all. When you do have relapses, recovery is not as complete. Along with these signs, there are other … Continue reading →

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