Alternative titles: disseminated sclerosis; MS Multiple sclerosis (MS), also called disseminated sclerosis, a progressive disease of the central nervous system characterized by the destruction of the myelin sheath surrounding the nerve fibres of the brain, spinal cord, and optic nerves. As a result, the transmission of nerve impulses becomes impaired, particularly in pathways involved with vision, sensation, and movement. MS has a worldwide distribution but is five times more common in temperate regions than in tropical regions. The disease primarily occurs in individuals between the ages of 20 and 40, and women are affected by the disease more often than men. There are four major types of MS: relapsing-remitting (RRMS), secondary-progressive (SPMS), primary-progressive (PPMS), and progressive-relapsing (PRMS). About 8085 percent of patients are diagnosed initially with RRMS. In this form of the disease, onset is usually gradual, and there are alternating intervals of symptom exacerbation and complete symptom remission. In many patients with RRMS, symptoms may worsen gradually during subsequent recurrences and eventually may no longer disappear during remissions. When this occurs, the patients diagnosis changes from RRMS to SPMS. About 1015 percent of patients have PPMS, which is characterized by steady disease progression from the time of onset, without … Continue reading
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