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Gene Therapy News — ScienceDaily

Posted: Published on March 31st, 2016

In Lung Cancer, Not All HER2 Alterations Are Created Equal Jan. 28, 2016 Study shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene. In patient samples of lung adenocarcinoma, 3 percent were found to have HER2 ... read more Dec. 12, 2015 Results from a long-term clinical trial conducted by cancer researchers show that combining radiation treatment with 'suicide gene therapy' provides a safe and effective one-two punch ... read more Gene Therapy Used to Extend Estrogen's Protective Effects on Memory Dec. 8, 2015 The hormone estrogen helps protect memory and promote a healthy brain, but this effect wanes as women age, and even estrogen replacement therapy stops working in humans after age 65. Now researchers ... read more Shrinking Tumors With an RNA Triple-Helix Hydrogel Glue Dec. 7, 2015 An efficient and effective delivery vehicle for gene therapy has been developed by researchers who have used it to shrink tumors by nearly 90 percent in a pre-clinical model of triple-negative breast ... read more Characteristics That May Increase a Breast Cancer Survivor's Risk of Developing Leukemia Following Treatment Identified Dec. 7, 2015 A new analysis indicates that certain characteristics … Continue reading →

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Human Gene Therapy

Posted: Published on March 31st, 2016

Editor-in-Chief: Terence R. Flotte, MD Deputy Editor, Europe: Thierry VandenDriessche, PhD Deputy Editor, U.S.: Barry J. Byrne, MD, PhD Human Gene Therapy Editor: Guangping Gao, PhD Methods Editor: Hildegard Bning, PhD Clinical Development Editor: James M. Wilson, MD, PhD Latest Impact Factor* is 3.755 *2014 Journal Citation Reports published by Thomson Reuters, 2015 Human Gene Therapy is the premier, multidisciplinary journal covering all aspects of gene therapy. The Journal publishes in-depth coverage of DNA, RNA, and cell therapies by delivering the latest breakthroughs in research and technologies. Human Gene Therapy provides a central forum for scientific and clinical information, including ethical, legal, regulatory, social, and commercial issues, which enables the advancement and progress of therapeutic procedures leading to improved patient outcomes, and ultimately, to curing diseases. The Journal is divided into three parts. Human Gene Therapy, the flagship, is published 12 times per year. HGT Methods, a bimonthly journal, focuses on the applications of gene therapy to product testing and development. HGT Clinical Development, a quarterly journal, serves as a venue for publishing data relevant to the regulatory review and commercial development of cell and gene therapy products. Human Gene Therapy was voted one of the most influential journals in … Continue reading →

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Rutgers-Newark Chemistry

Posted: Published on March 31st, 2016

DEPARTMENTAL NEWS N-H-- Interactions Stabilize Azaborine Oligomer and Polymer Conformations Isoxazole Chemistry Review Wins High Praise Pietrangelo Group Research Makes the Cover of Polymer Chemistry Award Competition: Herbert C. Cheung Scholarships, Anna and Bernard Senkowski Scholarships Each spring, the Chemistry Department runs an award competition open to all chemistry majors currently enrolled at Rutgers-Newark. To be eligible, a student must be a declared chemistry major by June of this year. Award winners are selected based upon the evaluation of grade-point average, financial need, and two letters of recommendation. The deadline for submitting application forms is June 10. Novel Tools in Computational Chemistry Coding Workshop Pavanello Group Research Makes the Cover of JCP BORAM XIV at Rutgers University-Newark in June Frieder Jkle Joins the Organometallics Advisory Board Prof. Jkle has been appointed to the Editorial Advisory Board of the journal Organometallics, published by the American Chemical Society. New Luminescent Triaryl Borane Polymers As Dual Responsive Fluoride Ion Sensors Recent Graduate Student Awards For the 2012-2013 academic year, Hetalaben Patel won a Graduate Student Excellence Award from the Graduate School Government, and Fei Cheng won the Graduate School Dean's Doctoral Dissertation Award. Ms. Patel is studying for a Ph.D. in Prof. Jordan's … Continue reading →

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DNA Wikipedie

Posted: Published on March 31st, 2016

Tento lnek pojednv onositelce genetick informace. Ometabolickm onemocnn pojednv lnek dna. Deoxyribonukleov kyselina, bn oznaovan DNA (z anglickho deoxyribonucleic acid, esky zdka iDNK), je nukleov kyselina, nositelka genetick informace vech organism svjimkou nkterch nebunnch, unich hraje tuto lohu RNA (nap. RNA viry). DNA je tedy pro ivot nezbytnou ltkou, kter ve sv struktue kduje a bukm zadv jejich program a tm peduruje vvoj a vlastnosti celho organismu. Ueukaryotickch organizm (jako nap. rostliny a ivoichov) je DNA hlavn slokou chromatinu, smsi nukleovch kyselin a protein, a je uloena zejmna uvnit bunnho jdra, zatmco uprokaryot (nap. bakterie a archea) se DNA nachz voln vcytoplazm. DNA je biologick makromolekula polymer v podob etzce nukleotid. Nukleotidy jsou vdy sloeny zcukru deoxyribzy, fosftov skupiny a jedn ze ty nukleovch bz. Informan funkci maj prv bze, jimi me bt adenin (A), guanin (G), cytosin (C) nebo thymin (T). Prvn dv pat mezi puriny, zbyl mezi tzv. pyrimidiny. Dv vlkna DNA se asto spojuj a vytvej dvouroubovici, jej tvar je tak slavn, e se stal kulturn ikonou modern doby.[1] Dvouroubovici DNA tvo dv navzjem spleten roubovice, kad mc opanm smrem (jsou antiparaleln). Mezi protilehlmi bzemi obou vlken se vytvej vodkov mstky, a to ti mezi guaninem a … Continue reading →

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Issues Archive – Cell Therapy News

Posted: Published on March 31st, 2016

Neon Therapeutics Enters Collaborative Research Agreement with the Netherlands Cancer Institute Neon Therapeutics announced that the company has entered into a collaborative research agreement with the Netherlands Cancer Institutes (NKI) Antoni van Leeuwenhoek Hospital and the Amsterdam Biotherapeutics Unit. Under the terms of the agreement, Neon Therapeutics and NKI will combine complementary capabilities to develop personalized T cell therapeutics. [Neon Therapeutics] PressRelease Juno Therapeutics, Seattle Cancer Care Alliance and Fred Hutchinson Cancer Research Center Announce New Immuno-Oncology Clinical Trials Unit Juno Therapeutics, Inc. and Fred Hutchinson Cancer Research Center announced the creation of a new, best-in-class clinical trials unit dedicated to immuno-oncology. [Juno Therapeutics, Inc.] PressRelease OncBioMune Continuing Phase I Trial, While Initiating Phase II Trial of ProscaVax for Prostate Cancer OncBioMune Pharmaceuticals, Inc. reported positive results from its Phase I clinical trial of ProscaVax, the companys novel cancer vaccine for prostate cancer. [OncBioMune Pharmaceuticals, Inc.] PressRelease Asterias Biotherapeutics Announces Successful End-of-Phase II Meeting with FDA for AST-VAC1 Asterias Biotherapeutics, Inc. announced the successful completion of an End-of-Phase II meeting with the U.S. Food and Drug Administration (FDA) for AST-VAC1, its investigational therapy targeting acute myeloid leukemia. [Asterias Biotherapeutics, Inc.] PressRelease Capricor Therapeutics Announces the First Patient with Duchenne Muscular … Continue reading →

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Biotechnology News — ScienceDaily

Posted: Published on March 31st, 2016

Need for Better Characterized Genomes for Clinical Sequencing Mar. 1, 2016 Challenges in benchmarking difficult, but clinically important regions of the genome have been reported. The results underscore the need to extend benchmarking references against which sequencing ... read more A New Way to Stretch DNA Mar. 1, 2016 Researchers have recently developed a new way to controllably manipulate materials, in this case biomolecules that are too small to see with the naked eye. By stretching molecules like DNA and ... read more Female Fertility Is Dependent on Functional Expression of the E3 Ubiquitin Ligase Itch Feb. 29, 2016 Protein ubiquitination is known to result in its proteasomal degradation or to serve as a signal for tissue-specific cellular functions. Here it is reported that mice with a mutant form of the E3 ... read more Cell Biology: Nuclear Export of Opioid Growth Factor Receptor Is CRM1 Dependent Feb. 29, 2016 The opioid growth factor receptor (OGFr) interacts with a specific opioid growth factor ligand (OGF), chemically termed [Met5]-enkephalin, to maintain homeostasis in a wide variety of normal and ... read more Making Better Enzymes and Protein Drugs Feb. 29, 2016 Natural selection results in protein sequences that are only soluble … Continue reading →

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Stem Cell Therapy in Switzerland Life Cell Injections …

Posted: Published on March 31st, 2016

Stem Cell Therapy Plus is also called Cell Therapy or Regenerative Medicine. Anecdotal evidence shows that through the usage of Stem Cell Therapy Plus, improvements can be seen in the following cases of degenerative diseases: Learn More Stem cells are cells with the ability to divide for indefinite periods in culture and to give rise to specialized cells. Stem cells have the remarkable potential to develop into many different cell types. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a nerve cell, or a brain cell. Stem Cell Supplements are developed based on the merits of stem cells and they are applied for degenerative diseases treatments and to stimulate the formation of all the different tissues of the body: muscle, cartilage, tendon, ligament, bone, blood, nerve, organs, etc. Stem Cell Supplements bring essential anti-ageing, health & beauty benefits by providing necessary elements to the body to improve cellular regeneration, organ rejuvenation and tissue … Continue reading →

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Biotechnology | University of Wisconsin-River Falls

Posted: Published on March 31st, 2016

Mission Statement The mission of the Biotechnology Program at the University of Wisconsin-River Falls is to provide its students with an education that establishes a strong foundation and appreciation for understanding developments in the rapidly advancing field of biotechnology, to develop the technical and critical thinking skills necessary for success in the field, to foster ethical behavior, and to promote outreach. The field of modern biotechnology was born of molecular biology and biochemistry. Modern Biotechnology provides a set of tools that allow scientists to modify and harness the genetic capabilities of organisms. This has led to rapid advances in many areas including pharmaceutical development, agriculture, food microbiology, medical devices and environmental sciences. Some examples of the products of biotechnology include herbicide, drought and insect resistant crops, drugs targeted specifically to disease processes resulting in fewer side effects, and bioremediation capable of removing greater amounts of environmental toxins at reduced cost. The Biotechnology major at UWRF is an interdepartmental program with an emphasis on the molecular basis of life and the techniques utilized to study and control these processes under in vivo, in vitro, and commercial production conditions. UWRF LogoThe Biotechnology curriculum is an integrated sequence of courses selected from the … Continue reading →

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Medical genetics – Wikipedia, the free encyclopedia

Posted: Published on March 31st, 2016

Medical genetics is the branch of medicine that involves the diagnosis and management of hereditary disorders. Medical genetics differs from human genetics in that human genetics is a field of scientific research that may or may not apply to medicine, while medical genetics refers to the application of genetics to medical care. For example research on the causes and inheritance of genetic disorders would be considered within both human genetics and medical genetics, while the diagnosis, management, and counselling people with genetic disorders would be considered part of medical genetics. In contrast, the study of typically non-medical phenotypes such as the genetics of eye color would be considered part of human genetics, but not necessarily relevant to medical genetics (except in situations such as albinism). Genetic medicine is a newer term for medical genetics and incorporates areas such as gene therapy, personalized medicine, and the rapidly emerging new medical specialty, predictive medicine. Medical genetics encompasses many different areas, including clinical practice of physicians, genetic counselors, and nutritionists, clinical diagnostic laboratory activities, and research into the causes and inheritance of genetic disorders. Examples of conditions that fall within the scope of medical genetics include birth defects and dysmorphology, mental retardation, autism, … Continue reading →

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About Genetics | Understanding Genetics

Posted: Published on March 31st, 2016

What is a Gene? Look closely at the chromosomes and you'd see that each is made of bundles of looping coils. If you unraveled these coils, you'd have a six-foot long double strand of deoxyribonucleic acid-DNA. A more+ How Do Genes Work? Genes are often called the blueprint for life, because they tell each of your cells what to do and when to do it: be a muscle, make bone, carry nerve signals, and so on. And how do genes orchestrate more+ Why We are Different Biologists use two fancy words to describe the relationship between your genes and your physical traits. The first word is genotype. Your genotype is your genes for a given trait. In most cases, more+ Mutations and Disease DNA is constantly subject to mutations, accidental changes in its code. Mutations can lead to missing or malformed proteins, and that can lead to disease. We all start out our lives with some more+ Genetic Testing Have you ever had your genes tested? Probably not. DNA testing is still pretty limited, although it is becoming more and more common, especially for fetuses and newborns. Many prospective parents, more+ Making Medicines Not long ago, if you were diabetic, … Continue reading →

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