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Stem Cell Sciences, Inc. – Stem Cell Research

Posted: Published on August 1st, 2015

Current Research We are currently engaged in optimization of culture conditions of human bone marrow derived mesenchymal (stromal) stem cells for their expansion and differentiation into cartilage forming cells for the future repair of cartilage defects occurring in osteoarthritis and rheumatoid arthritis. A proprietary system is being explored for the delivery of these cells to the precise location of defects. The research is aimed also to demonstrate (via collaborative efforts with another institution) the lack of any cancer promoting ability in these cultured cells. Future Research We intend to optimize the expansion of marrow-derived mesenchymal (stromal) stem cells and to demonstrate their immune modulatory properties to allow future cellular therapy for Inflammatory Bowel Diseases: Ulcerative Colitis and Crohns Disease. Once this goal is reached, research could expand to other immune-related diseases. Funding Needs So far, all research has been funded from internal sources. In the near future, we are interested in private equity funding. In addition, applications for government small business grants are being considered. View post: Stem Cell Sciences, Inc. - Stem Cell Research … Continue reading →

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Stem Cell Trial ALS Clinic

Posted: Published on August 1st, 2015

Stem cell transplantation study for the treatment of ALS Phase 2 The phase 2 trial focused on the safety and maximum tolerated dose of Human Spinal Cord Derived Neural Stem Cell Transplantation. This study expanded on the work of the phase 1 study directed by Eva L. Feldman, M.D., Ph.D., who is the principal investigator and director of the first-ever FDA-approved human clinical trial of stem cells injected directly into the spinal cords of ALS patients. Phase 1 of the trial, designed to study the safety of the procedure, was completed in 2013 with no significant adverse side effects to patients. And follow-up patient evaluations have produced some extraordinary data: Several participants in the trial, who were treated early in their disease, were determined to have had little or no significant progression of ALS for more than 700 days post-surgery. Updated July 2015: Fifteen patients were studied in the phase 2 study, the last 3 of which received 8 million stem cells injected into the lumbar spinal cord followed by 8 million stem cells injected into the cervical spinal cord. All procedures have been completed and the trial is still ongoing. No data has been released. https://clinicaltrials.gov/show/NCT01730716 Future trials Updated … Continue reading →

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Cerebral palsy – Treatment – NHS Choices

Posted: Published on July 31st, 2015

Treating cerebral palsy There is no cure for cerebral palsy, but a range of treatments are available to help treat many of the symptoms. Treatment for cerebral palsy will usually involve a team of health professionals with different areas of expertise.The team may include: The care team will help draw up an individual care plan to address any needs or problems your child has. The plan will be continually reassessed as your child gets older and their needs change. You and your child will also be assigned a key worker, who will be the first point of contact between you and the various support services available. When your child is young, the key worker is likely to be a health visitor. As your child gets older and their needs become more complex, the key worker is likely to be a social worker. There is no single treatment plan for a child with cerebral palsy. Instead, there are a wide range of treatments available, which are designed to improve your child's symptoms and let them be as independent as possible. Some of the main treatments are outlined below. Physiotherapyis normally started when your child is diagnosed with cerebral palsy. It is … Continue reading →

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Multiple Sclerosis, Wheelchairs and Lifespan | Multiple …

Posted: Published on July 31st, 2015

My wife made a comment last week that Ive thought about a lot since she said it. It was said in passing in the middle of a conversation that I cannot remember (apparently, my wifes not the only person in our family with poor memory). In this case, though, I think I fail to remember the rest of the conversation because her comment stunned me. I dont think Ill live a long life. I knew if I talked to her about it then, I would become too assertive about how wrong I thought the statement was and that she had no right to think that way. (Actually, she has the right to think any way she wishes and usually does even if I dont like it!) I knew, though, I wouldnt be able to listen to what she was really saying. So, a week later, yesterday morning, I asked her about her comment. I imagine you said it because you have MS, but having MS doesnt mean youll have a shorter life. Are you thinking youll have a shorter life because of something youve read? Or is it just a hunch? Shes a realist and a pragmatist. I need the … Continue reading →

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Bone marrow transplantation (BMT) and hematopoietic cell …

Posted: Published on July 31st, 2015

What are hematopoietic cell transplantation (HCT) and peripheral blood stem cell transplantation (PBSCT)? HCT and PBSCT are procedures that use stem cells to treat a patient's malignancy or to repair diseased or defective bone marrow. A patient receives intensive chemotherapy with or without total body irradiation therapy in an attempt to kill all cancerous cells, but which also destroy his/her own bone marrow function. This therapy also causes immunosuppression, which prevents rejection of the newly transplanted stem cells from a related or unrelated donor. There is little risk of rejection of a patient's own stem cells following autologous transplant. After transplantation, the new stem cells replace the damaged bone marrow and cells of the immune system. HCT and PBSCT allow a patient to receive very high doses of chemotherapy and radiation designed to kill cancer cells. The high doses of therapy lead to the destruction of a patient's own marrow and immune system, which is then replaced by marrow from a donor or from peripheral blood stem cells that have been harvested before therapy. City of Hope has performed more than 12,000 transplants for patients from virtually every state as well as from numerous countries. HCT and PBSCT patients at … Continue reading →

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iitropar-chemistry – Google Sites

Posted: Published on July 28th, 2015

News and Event Prof. Pratim K Chattaraj, Department of Chemistry and Center for Theoretical Studies, IIT Kharagpur, will give a seminar on, "All-metal aromaticity and conceptual DFT", on 29 June 2015 at 3:00 pm conference room 2 The DSC meeting to review the progress of Ph. D. students in the department is scheduled at 9:30 am on 26 and 30 June 2015 in conference room 1 The comprehensive and scholarship enhancement seminar of Hrishikesh Mukherjee, Ph. D. student, is scheduled on 30 June 2015 at 2:30 pm in conference room 2 Welcome to the website of Department of Chemistry at IIT Ropar! The department is actively engaged in cutting-edge research in emerging areas like Biomaterials, Biosensors, Catalysis, Drug Delivery, Materials, Organometallic Chemistry, Renewable Energy, Supramolecular Syntheses, Synthetic Organic Chemistry, Theoretical Chemistry, etc. The research activities at the department are supported by a large number of sponsored research projects and state-of-the-art research facilities that exist at the department and institute levels. The department is served by nine faculty and an INSPIRE fellow, and more than thirty PhD students and project fellows. The department is visited by a large number of experts and short-term students from India and abroad. Learn more about … Continue reading →

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Epilepsy Treatment | Conditions & Treatments | UCSF …

Posted: Published on July 26th, 2015

Your neurology team at the Epilepsy Center, along with your primary care doctor, will design a treatment plan tailored to your condition and individual needs. You may require more than one kind of treatment such as medication and surgery and may be referred to other medical professionals. Most seizures can be prevented with medication. The type of medication prescribed will depend on your condition. Your neurologist will explain how to take your medication and what side effects might occur. Over time, your medication may be changed to find the right drug and dose. Be sure to take your medication as directed. Call your neurologist if you have questions or experience any unexpected side effects. For some patients, surgery may be recommended to prevent seizures or to implant devices that deliver medications or stimulators to emit electrical impulses. Your neurologist will explain the procedure as well as possible risks. These procedures include: If you have a vagus nerve stimulator implanted, you'll continue to take medication but may be able to reduce the amount or number of medications. This procedure can treat a wide variety of seizure disorders when other surgical procedures aren't an option. Most medical treatments may involve some risks … Continue reading →

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Muscular Dystrophy News — ScienceDaily

Posted: Published on July 25th, 2015

Likely Genetic Source of Muscle Weakness Found in Six Previously Undiagnosed Children Apr. 9, 2015 Using state-of-the-art genetic technology, researchers have discovered the likely cause of a child's rare type of severe muscle weakness. The child was one of six cases in which investigators ... read more Scientists Identify New Disease Treatment Path Jan. 26, 2015 A previously unknown phenomenon -- that diseased muscle cells literally eat themselves to death -- has been discovered by researchers. The researchers say this previously unrecognised mechanism could ... read more Hope for Muscular Dystrophy Patients: Harnessing Gene Helps Repair Muscle Damage Jan. 15, 2015 Researchers have successfully improved the ability of muscle to repair itself -- by artificially increasing levels of the BMI1 gene in the muscle-specific stem cells of mice with muscular ... read more Jan. 12, 2015 Researchers have developed a way to measure upper extremity movement in patients with muscular dystrophy using interactive video game technology. Their hope is to expand inclusion criteria for ... read more Dec. 30, 2014 Early use of available heart failure drugs slows the progressive decline in heart function before symptoms are apparent in boys and young men with Duchenne muscular dystrophy (DMD), according to … Continue reading →

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Autism Treatment Center – Biomedical and Hyperbaric …

Posted: Published on July 25th, 2015

Autism Treatment Center of Newtown Square is a state-of-the-art comprehensive center for the treatment of Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD) and Developmental Delay, integrating mainstream behavioral therapy with innovative, cutting-edge biomedical interventions. Our belief is that Autism Spectrum Disorder is an acquired condition (of newly epidemic proportion), caused by a combination of complex environmental factors and genetic predisposition. Resulting toxicities and immune dysfunction ultimately combine to cause neurologic deficits and brain injury. Based on this theory, we believe these disorders are treatable, utilizing the integration of mainstream behavioral and biomedical intervention to yield the greatest possible results. The combined therapeutic effect of biomedical and behavioral therapies will improve focus and attention, decrease anxiety, increase cognition and overall neurologic function and serve as a comprehensive treatment program. The ultimate goal of the Autism Treatment Center of Newtown Square is to minimize the family burden by providing multiple therapies in one centralized location while maximizing the potential for recovery in every child. The Autism Treatment Center of Newtown Square will provide multiple therapies, for the treatment of Autism Spectrum Disorder(ASD), Attention Deficit Hyperactivity Disorder (ADHD) and Developmental Delay in one centralized location while maximizing the potential for recovery … Continue reading →

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Dietary treatment of gluten ataxia – National Center for …

Posted: Published on July 25th, 2015

J Neurol Neurosurg Psychiatry. 2003 Sep; 74(9): 12211224. Background: Gluten ataxia is an immune mediated disease, part of the spectrum of gluten sensitivity, and accounts for up to 40% of cases of idiopathic sporadic ataxia. No systematic study of the effect of gluten-free diet on gluten ataxia has ever been undertaken. Objective: To study the effect of gluten-free diet on patients presenting with ataxia caused by gluten sensitivity. Methods: 43 patients with gluten ataxia were studied. All were offered a gluten-free diet and monitored every six months. All patients underwent a battery of tests to assess their ataxia at baseline and after one year on diet. Twenty six patients (treatment group) adhered to the gluten-free diet and had evidence of elimination of antigliadin antibodies by one year. Fourteen patients refused the diet (control group). Three patients had persistently raised antigliadin antibodies despite adherence to the diet and were therefore excluded from the analysis. Results: After one year there was improvement in ataxia reflected in all of the ataxia tests in the treatment group. This was significant when compared with the control group. The diet associated improvement was apparent irrespective of the presence of an enteropathy. Conclusions: Gluten ataxia responds to … Continue reading →

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