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Allogeneic Mesenchymal Stem Cells for the Treatment of …

Posted: Published on July 9th, 2015

Statement of Benefit to California: Acute lung injury is a common cause of acute respiratory failure in critically ill patients. Based on recent studies, acute lung injury occurs annually in approximately 24,000 patients in California alone with an estimated mortality of 40% in those patients. Acute lung injury can develop in normal individuals who have been injured in major trauma, such as following an automobile accident or from exposure to smoke fumes in a fire. It also can occur in otherwise normal individuals who develop severe pneumonia from a viral infection, such as the flu. Acute lung injury also develops in patients with a variety of chronic medical illnesses including diabetes, chronic lung diseases, liver disease and dialysis dependent kidney failure. Acute lung injury develops in both pediatric and adult patients and treatment is required in an intensive care unit where patients can receive life support with mechanical ventilation and other life saving therapies. In spite of progress in supportive care for this syndrome of acute respiratory failure, 40% of patients with acute lung injury do not survive. Also, the patients who do survive require long periods of hospitalization to recover and also require extended periods of rehabilitation in specialized … Continue reading →

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Multiple Sclerosis: Hope Through Research: National …

Posted: Published on July 8th, 2015

Multiple Sclerosis (MS) is the most common disabling neurological disease of young adults. It most often appears when people are between 20 to 40 years old. However, it can also affect children and older people. The course of MS is unpredictable. A small number of those with MS will have a mild course with little to no disability, while another smaller group will have a steadily worsening disease that leads to increased disability over time. Most people with MS, however, will have short periods of symptoms followed by long stretches of relative relief, with partial or full recovery. There is no way to predict, at the beginning, how an individual persons disease will progress. Researchers have spent decades trying to understand why some people get MS and others don't, and why some individuals with MS have symptoms that progress rapidly while others do not. How does the disease begin? Why is the course of MS so different from person to person? Is there anything we can do to prevent it? Can it be cured? This brochure includes information about why MS develops, how it progresses, and what new therapies are being used to treat its symptoms and slow its progression. … Continue reading →

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Dna | Define Dna at Dictionary.com

Posted: Published on July 8th, 2015

1. Genetics. deoxyribonucleic acid: an extremely long macromolecule that is the main component of chromosomes and is the material that transfers genetic characteristics in all life forms, constructed of two nucleotide strands coiled around each other in a ladderlike arrangement with the sidepieces composed of alternating phosphate and deoxyribose units and the rungs composed of the purine and pyrimidine bases adenine, guanine, cytosine, and thymine: the genetic information of DNA is encoded in the sequence of the bases and is transcribed as the strands unwind and replicate. 2. the set of nongenetic traits, qualities, or features that characterize a person or thing: Humility is just not in her DNA. Examples from the web for DNA Expand British Dictionary definitions for DNA Expand Word Origin and History for DNA Expand 1944, abbreviation of deoxyribonucleic acid (1931). DNA in Medicine Expand DNA (d'n-') n. Deoxyribonucleic acid; a nucleic acid that consists of two long chains of nucleotides twisted together into a double helix and joined by hydrogen bonds between complementary bases adenine and thymine or cytosine and guanine; it carries the cell's genetic information and hereditary characteristics via its nucleotides and their sequence and is capable of self-replication and RNA synthesis. DNA … Continue reading →

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Dyshidrotic Eczema Pictures, Causes, Home Remedies …

Posted: Published on July 7th, 2015

What is Dyshidrotic Eczema? This is a skin problem which is also known as dyshidrosis, or pompholyx. This skin condition creates fluid-filled, small blisters or vesicles on the soles of the feet or palms of the hands or both. These blisters occurring in dyshidrotic eczema normally last around 3 weeks and causes extreme itching. When these blisters dry, cracks and groves or fissures develop, which are very painful. Management for dyshidrotic eczema most often requires topical creams, ultraviolet light or wet compresses to improve the appearance as well as ease symptoms. The cause of dyshidrotic eczema is not known. But, it can be linked with a similar disorder of the skin known as atopic dermatitis as well as allergic conditions, for instance asthma and hay fever known as allergic rhinitis. Eruptions can be seasonal in individuals with allergies. With dyshidrotic eczema, the affected areas of the skin come to be inflamed. Because of this, the connections between the cells of the skin open and this allows fluid or serum to seal these spaces. Physicians denote this development as spongiosis since when viewed under microscope; the skin appears sponge-like with these numerous fluid-filled spaces. Signs or symptoms of dyshidrotic eczema include: … Continue reading →

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Medical Genetics at University of Washington

Posted: Published on July 7th, 2015

Medical Genetics Faculty, Fellows & Staff: 2014 The University of Washington Department of Medicine is recruiting for one (1) full-time faculty position at the Associate Professor, or Professor level in the Division of Medical Genetics, Department of Medicine. This position is offered with state tenure funding. Successful candidates for this position will have an M.D./Ph.D. or M.D. degree (or foreign equivalent), clinical expertise in genetics, and will be expected to carry out a successful research program. Highly translational PhD (or foreign equivalent) scientists may be considered. Although candidates with productive research programs in translational genetics/genomics and/or precision medicine will be prioritized, investigators engaged in gene therapy research may also be considered. The position will remain open until filled. Send CV and 1-2 page letter of interest to: Medical Genetics Faculty Search c/o Sara Carlson Division of Medical Genetics University of Washington seisner@u.washington.edu Read the rest here: Medical Genetics at University of Washington … Continue reading →

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Genetic engineering: a guide for kids by Tiki the Penguin

Posted: Published on July 7th, 2015

Genetic engineering (GE for short) is about scientists altering the 'recipes' for making life the genes which you find in all living things. Doing this is very clever and seems to be very useful. Back in the 1990s, many 'Greens' campaigned against genetic engineering and still do. They predicted disaster but that hasn't happened. Nobody has died from eating genetically modified (GM) food. They were also worried about the private GE companies' ownership of the recipes genes for making these new life forms. So is genetic engineering okay? My guide explains the basics but it's up to you to make up your own mind about GE. Finding your way around my GE Guide You can jump to any part that interests you from the table below. If you want to start at the beginning, click the green arrow below (forward to 'Genes, snails and whales'). Table of contents Genes, snails and whales What makes you human or me a penguin? What are genes? Tried and tested Life on Earth has been around for a long time so it's been well tested. Adapt or die Only the fittest life survives. Here's how it does it. Coils and corkscrews About that incredible … Continue reading →

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Stem Cells, FDA, and the Edge of Science: Three Expert …

Posted: Published on July 7th, 2015

Last week I wrote about a pending lawsuit by the FDA against Regenerative Sciences,a medical company thatdevelopeda stem cell treatment for orthopedic injuries. Whileadult stem cell therapies have been fraught with concerns about safetyand efficacy, this case is particularly important not only because it is unprecedented the FDA is attempting toclassify non-embryonicstem cellsas drugs but also because itbrings into focusthe disconnect between the pace of scientific progressand the struggle ofregulatorsto keep up withrapidly evolving technologies. I spoke withthree people with aunique perspective onwhats at stake a lawyer who specializes in FDA regulation, a lab director of an in-vitro fertilization clinic, and a bioethicist to geta sense of how thecase is viewed intheir industries. One common threadthat emergedfrom these conversations is that the FDA is conflicted, even confused,about how to regulate stem cell-based products.Theprolonged legal battle with Regenerative(it dates back to at least 2008) is duelargely to the fact that the agency recognizes the absurdity of coming down with a one-size-fits-all regulatory approach thatwould apply to every clinicoffering such treatments. To be sure, stem cell medicine has a terrible reputation.Stem cell therapies thatpurport to treateverything fromshot knees and slipped disks toautism, multiple sclerosis,and Parkinsons diseaseare rightlyregarded by many as modern-day quackery. … Continue reading →

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Stem-cell Research and the Catholic Church

Posted: Published on July 6th, 2015

ORLANDO, Fla. (CNS) Declaring that stem-cell research does not present a conflict between science and religion, the U.S. bishops overwhelmingly approved a statement June 13 calling the use of human embryos in such research "gravely immoral" and unnecessary. In the last vote of the public session of their June 12-14 spring general assembly in Orlando, the bishops voted 191-1 in favor of the document titled "On Embryonic Stem-Cell Research: A Statement of the U.S. Conference of Catholic Bishops." "It now seems undeniable that once we cross the fundamental moral line that prevents us from treating any fellow human being as a mere object of research, there is no stopping point," the document said. "The only moral stance that affirms the human dignity of all of us is to reject the first step down this path." Archbishop Joseph F. Naumann of Kansas City, Kan., introduced the document on behalf of Philadelphia Cardinal Justin Rigali, chairman of the bishops' Committee on Pro-Life Activities, who was not at the Orlando meeting. Consideration of the stem-cell document came after an intense and complicated debate at the meeting over a 700-page liturgical translation. Archbishop Naumann thanked those involved in the liturgical debate for "making stem-cell … Continue reading →

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Application of human mesenchymal and pluripotent stem cell …

Posted: Published on July 6th, 2015

Abstract Mesenchymal stem cells (MSCs) have recently made significant progress with multiple clinical trials targeting modulation of immune responses, regeneration of bone, cartilage, myocardia, and diseases like Metachromatic leukodystrophy and Hurler syndrome. On the other hand, the use of human embryonic and induced pluripotent stem cells (hPSCs) in clinical trials is rather limited mainly due to safety issues. Only two clinical trials, retinal pigment epithelial transplantation and treatment of spinal cord injury were reported. Cell doses per treatment can range between 50,000 and 6billion cells. The current 2-dimensional tissue culture platform can be used when low cell doses are needed and it becomes impractical when doses above 50million are needed. This demand for future cell therapy has reinvigorated interests in the use of the microcarrier platform for generating stem cells in a scalable 3-dimensional manner. Microcarriers developed for culturing adherent cell lines in suspension have been used mainly in vaccine production and research purposes. Since MSCs grow as monolayers similar to conventional adherent cell lines, adapting MSCs to a microcarrier based expansion platform has been progressing rapidly. On the other hand, establishing a robust microcarrier platform for hPSCs is more challenging as these cells grow in multilayer colonies on extracellular … Continue reading →

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AAAMS – Teaching the Art of Aesthetic Medicine & Surgery

Posted: Published on July 6th, 2015

Are you a medical professional who is interested in learning more about the latest dermatology & aesthetics techniques? Have you been searching for a professional aesthetics training course in which you can earn certification? The American Association of Aesthetic Medicine & Surgery (AAAMS) provides training for medical professionals in aesthetic procedures. Our courses are specifically designed to inform practitioners of the basic approach of aesthetic medicine procedures and surgery training. Trained over a thousand physicians, nurses and practitioners since 2006 Offer the most comprehensive wide range of training courses Courses taught by qualified physicians in over eight languages in classes around the globe Set the international standard in aesthetic medicine & surgery training Cosmetic Surgeons Plastic Surgeons Dermatologists General Surgeons Internists and Family Practitioners Nurses and Nurse Practitioners Physician Assistants and Allied Health Professionals Anesthesiologists Emergency Medicine Specialists Obstetricians and Gynecologists Dentists and Dental Allied Health Professionals The American Association of Aesthetic Medicine & Surgery (AAAMS) is committed to training physicians, registered nurses and practitioners in the art of aesthetics and non-invasive cosmetic surgery through a practical, clear-cut approach with safety in mind. Read the original here: AAAMS - Teaching the Art of Aesthetic Medicine & Surgery … Continue reading →

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