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Parkinson’s Disease Treatments – Standard Treatments for …

Posted: Published on June 22nd, 2015

2001-2008 HAAP Media Ltd Updated February 09, 2015. Although there is as yet no cure for Parkinsons Disease (PD), scientists are hot on the track for better treatments to manage its symptoms. There is also a search for treatments that can slow the progression of the disease. Drug therapy to both manage the symptoms of PD, and slow the progression of the disease, remains the Gold Standard treatment option for PD. Levodopa increases the level of dopamine in the brain and thus relieves the movement problems of PD. Levodopa however has side effects. One of Levodopas common side effects is nausea so it is usually given with a second drug, carbidopa, that prevents nausea. The combination of Levodopa/Carbidopa effectively treats the symptoms of PD, allowing many people with PD to live relatively normal, active, and productive lives for many years. Dopamine Agonists are a class of drugs that, like levodopa, increase dopamine activity in the brain. Commonly prescribed dopamine agonists include: bromocriptine (Parlodel), pergolide (Permax), pramiprexole (Mirapex), and ropinirole (Requip). They do not work as well as levodopa for the movement problems of PD but they may be able to slow progression of the disease. A small percentage of patients … Continue reading

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Cerebral Palsy: Causes, Treatment and Prevention

Posted: Published on June 22nd, 2015

Cerebral palsy refers to a group of conditions that affect control of movement and posture. Because of damage to areas of the brain that control movement, an affected child cannot move his or her muscles normally. While symptoms range from mild to severe, the condition does not get worse as the child gets older. With treatment, most children can significantly improve their abilities. Many children with cerebral palsy have other problems that require treatment. These include mental retardation, learning disabilities, seizures, vision, hearing and speech problems. Cerebral palsy usually is not diagnosed until a child is about 2 to 3 years of age. Approximately 2 to 3 children in 1,000 over the age of three have cerebral palsy. About 500,000 children and adults of all ages in this country have cerebral palsy. There are three major types of cerebral palsy, and some individuals may have symptoms of more than one type. About 70 to 80 percent of affected individuals have spastic cerebral palsy, in which muscles are stiff, makingmovement difficult. When both legs are affected (spastic diplegia), a child may have difficulty walking because tight muscles in thehips and legs cause legs to turn inward and cross at the knees … Continue reading

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Autism Treatment, Prognosis – Autism – HealthCommunities.com

Posted: Published on June 21st, 2015

Treatment for Autism There is no cure for autism; however, with appropriate treatment and education, many children with autism spectrum disorders can learn and develop. Early intervention often can reduce challenges associated with autism, lessen disruptive behavior, and provide some degree of independence. Treatment depends on the needs of the individual. In most cases, a combination of treatment methods is more effective. Autism spectrum disorders may require lifelong treatment. According to the National Institutes of Health (NIH), treatment for autism can include the following: Occupational therapy helps improve independent function and teaches basic skills (e.g., buttoning a shirt, bathing). Physical therapy involves using exercise and other physical measures (e.g., massage, heat) to help people with autism spectrum disorders control body movements. There are several methods of behavior modification that are used to treat inappropriate, repetitive, and aggressive behavior and to provide autistic people with skills necessary to function in their environment. Most types of behavior modification are based on the theory that rewarded behavior is more likely to be repeated than behavior that is ignored. This theory is called applied behavior analysis (ABA). Behavior modification often involves highly structured, skill-oriented activities that are based on the individual's needs and interests. … Continue reading

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Mesenchymal Stem Cells – Advances & Applications

Posted: Published on June 20th, 2015

Understand and profit from the mesenchymal stem cell (MSC) product market the fastest growing area of stem cell research. Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, beta-pancreatic islets cells, and potentially, neuronal cells. MSCs are of intense therapeutic interest because they represent a population of cells with the potential to treat a wide range of acute and degenerative diseases. To Browse a Full Report with TOC: http://www.researchmoz.us/mesenchymal-stem-cells-advances-and-applications-2013-report.html MSCs are advantageous over other stem cells types for a variety of reasons: they avoid the ethical issues that surround embryonic stem cell research, and repeated studies have found MSCs to be immuno-privileged, which make them an advantageous cell type for allogenic transplantation. MSCs reduce both the risks of rejection and complications of transplantation. Recently, there have been advances in the use of autologous mesenchymal stem cells to regenerate human tissues, including cartilage, meniscus, tendons, bone fractures, and more. Trend analysis of grant activity, scientific publication rates, and patent applications trends reveal that global research activity involving mesenchymal stem cells (MSCs) increased 112% from 2009 to 2010, and 116% from 2010 to 2011. Of most interest is that … Continue reading

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Stem cell expert: Bart Starr treatment shows need for …

Posted: Published on June 19th, 2015

The news that legendary Green Bay Packer quarterback Bart Starr has undergone stem cell therapy to recover from a stroke has raised the profile for a promising but unproven regenerative treatment intended to replace dead neurons with live ones. The University of Wisconsin-Madison's Su-Chun Zhang was the first scientist to isolate neural stem cells from embryonic stem cells and then from other types of all-purpose stem cells. He says medical researchers and the federal government have a responsibility to forge ahead with clinical trials to prove whether and how these flexible cells can replace damaged or dead neural cells caused by spinal cord injury, stroke and Lou Gehrig's disease (ALS). Su-Chun Zhang "We have no effective treatment for stroke," says Zhang, a medical doctor and Ph.D. researcher at the UW's Waisman Center. "After a couple of hours, the cells are dead if they don't have a blood supply. And the brain has a very limited capacity to regenerate, particularly in older patients." Embryonic stem cells the cells that give rise to all body tissues were first cultured by James Thomson at UW-Madison in 1998. Just three years later in 2001 Zhang discovered how to grow neural cells from embryonic stem … Continue reading

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Mesenchymal Stem Cells Market – Global Industry Analysis …

Posted: Published on June 19th, 2015

Mesenchymal stem cells are the adult stem cells. Mesenchymal stem cells are of various types such as monocytes, adipocytes, osteocytes and chondrocytes. Mesenchymal stem cells main function is to replace or repair damage tissue. In addition, mesenchymal stem cells have high potential for tissue repair. Mesenchymal stem cells are isolated from other tissues such as fallopian tube, cord blood, fetal liver, peripheral blood and fetal lung. Mesenchymal stem cells are renewable source to substitute tissue and cells to treat disabilities and diseases. North America dominates the global market for mesenchymal stem cell due to large number of aging population and increasing incidence of cancers. Asia is expected to show high growth rates in the next five years in the global mesenchymal stem cell market. China and India are expected to be the fastest growing mesenchymal stem cell markets in Asia-Pacific region. Some of the key driving forces for mesenchymal stem cell market in emerging countries are large pool of patients and rising government funding and support. Buy Full Mesenchymal Stem Cells MarketReport:http://www.persistencemarketresearch.com/market-research/mesenchymal-stem-cells-market.asp In recent times there is increased use of mesenchymal stem cell due to increasing aging population. Rising incidence of chronic diseases, regulatory and government support and increasing investment … Continue reading

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In Vitro and In Vivo Studies of Non-Platinum-Based …

Posted: Published on June 18th, 2015

Highlights Femtomedicine may accelerate drug discovery for effective treatment of cancer. A previously undiscovered class of non-platinum-based halogenated compounds is found to have potent antitumor effects. FMD agents can be used for natural targeted chemotherapy of multiple types of cancer while inducing minimal toxicity. Based on a molecular-mechanism-based anticancer drug discovery program enabled by an innovative femtomedicine approach, we have found a previously unknown class of non-platinum-based halogenated molecules (called FMD compounds) as potent antitumor agents for effective treatment of cancers. Here, we present in vitro and in vivo studies of the compounds for targeted chemotherapy of cervical, breast, ovarian, and lung cancers. Our results show that these FMD agents led to DNA damage, cell cycle arrest in the S phase, and apoptosis in cancer cells. We also observed that such a FMD compound caused an increase of reduced glutathione (GSH, an endogenous antioxidant) levels in human normal cells, while it largely depleted GSH in cancer cells. We correspondingly found that these FMD agents exhibited no or little toxicity toward normal cells/tissues, while causing significant cytotoxicity against cancer cells, as well as suppression and delay in tumor growth in mouse xenograft models of cervical, ovarian, breast and lung cancers. These … Continue reading

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Stem Cell Research & Therapy | Full text | Aromatic …

Posted: Published on June 16th, 2015

Abstract Introduction Aromatic (ar-) turmerone is a major bioactive compound of the herb Curcuma longa. It has been suggested that ar-turmerone inhibits microglia activation, a property that may be useful in treating neurodegenerative disease. Furthermore, the effects of ar-turmerone on neural stem cells (NSCs) remain to be investigated. We exposed primary fetal rat NSCs to various concentrations of ar-turmerone. Thereafter, cell proliferation and differentiation potential were assessed. In vivo, nave rats were treated with a single intracerebroventricular (i.c.v.) injection of ar-turmerone. Proliferative activity of endogenous NSCs was assessed in vivo, by using noninvasive positron emission tomography (PET) imaging and the tracer [18F]-fluoro-L-thymidine ([18F]FLT), as well as ex vivo. In vitro, ar-turmerone increased dose-dependently the number of cultured NSCs, because of an increase in NSC proliferation (P … Continue reading

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Treatments for Epilepsy. Medications to treat epilepsy …

Posted: Published on June 15th, 2015

Medication for epilepsy Epilepsy cannot be cured with medication. However, with the right type and strength of medication, the majority of people with epilepsy do not have seizures. The medicines work by stabilising the electrical activity of the brain. You need to take medication every day to prevent seizures. These include:Carbamazepine, clobazam, clonazepam, eslicarbazepine, ethosuximide, gabapentin, lacosamide, lamotrigine, levetiracetam, oxcarbazepine, perampanel, phenobarbital, phenytoin, pregabalin, primidone, retigabine, rufinamide, sodium valproate, tiagabine, topiramate, vigabatrin and zonisamide. They all come with different brand names. The success in controlling seizures by medication varies depending on the type of epilepsy. For example, if no underlying cause can be found for your seizures (idiopathic epilepsy), you have a very good chance that medication can fully control your seizures. Seizures caused by some underlying brain problems may be more difficult to control. The overall outlook is better than many people realise. The following figures are based on studies of people with epilepsy, which looked back over a five-year period. These figures are based on grouping people with all types of epilepsy together which gives an overall picture: Deciding on which medicine to prescribe depends on such things as: There are popular first choice medicines for each type … Continue reading

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Seizure (Epilepsy) Symptoms, Causes, Treatment – What …

Posted: Published on June 15th, 2015

What Causes Epilepsy? Epilepsy is a disorder with many possible causes. Anything that disturbs the normal pattern of neuron activity -- from illness to brain damage to abnormal brain development -- can lead to seizures. Epilepsy may develop because of an abnormality in brain wiring, an imbalance of nerve signaling chemicals called neurotransmitters, or some combination of these factors. Researchers believe that some people with epilepsy have an abnormally high level of excitatory neurotransmitters that increase neuronal activity, while others have an abnormally low level of inhibitory neurotransmitters that decrease neuronal activity in the brain. Either situation can result in too much neuronal activity and cause epilepsy. One of the most-studied neurotransmitters that plays a role in epilepsy is GABA, or gamma-aminobutyric acid, which is an inhibitory neurotransmitter. Research on GABA has led to drugs that alter the amount of this neurotransmitter in the brain or change how the brain responds to it. Researchers also are studying excitatory neurotransmitters such as glutamate. In some cases, the brain's attempts to repair itself after a head injury, stroke, or other problem may inadvertently generate abnormal nerve connections that lead to epilepsy. Abnormalities in brain wiring that occur during brain development also may … Continue reading

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