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Spinal Cord Injury,Stem Cell Therapy Spinal Cord Treatment …

Posted: Published on June 15th, 2015

Overview Spinal Cord Injury - Stem Cell Treatment in India In 1995, actor Christopher Reeve fell off a horse and severely damaged his spinal cord, leaving him paralyzed from the neck down. From then until his death in 2004, the silver screen Superman became the most famous face of spinal cord injury. Most spinal cord injury causes permanent disability or loss of movement (paralysis) and sensation below the site of the injury. Paralysis that involves the majority of the body, including the arms and legs, is called quadriplegia or tetraplegia. When a spinal cord injury affects only the lower body, the condition is called paraplegia. Christopher Reeve's celebrity and advocacy raised national interest, awareness and research funding for spinal cord injury. Many scientists are optimistic that important advances will occur to make the repair of injured spinal cords a reachable goal. In the meantime, treatments and rehabilitation allow many people with spinal cord injury to lead productive, independent lives. A complete spinal cord injury is defined by total or near-total loss of motor function and sensation below the area of injury. However, even in a complete injury, the spinal cord is almost never completely cut in half. Doctors use the … Continue reading →

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Thoracic Spinal Cord Injury: Diagnosis & Treatment

Posted: Published on June 15th, 2015

Diagnosis and Treatment of Thoracic Spinal Cord Injury By Wise Young, Ph.D., M.D. W. M. Keck Center for Collaborative Neuroscience Rutgers University, Piscataway, New Jersey http:sciwire.com, last updated 23 July 2005 Many people have been asking for an article about diagnosis and treatment of thoracic spinal cord injury. The following is a short description of upper and mid-thoracic spinal cord injury, emphasizing the anatomy, the neurology, treatment, recovery, and long-term changes, and hope for recovery and therapies. Anatomy The thoracic spinal cord is situated in the T1-T9 thoracic spinal canal. The thoracic vertebral segments form the chest wall and have ribs. The thoracic segments are the best protected of all the vertebral segments because of the ribs. It takes enormous forces to fracture the thoracic spinal vertebral bodies. Traumatic injuries of the upper thoracic spinal cord are relatively rare, accounting for only 10-15% of spinal cord injuries (compared to 40% due to cervical, 35% due to thoracolumbar injuries, and 5% due to lumbosacral injuries). Thoracic spinal cord injuries occur as a result of high-speed motor vehicular accidents, tumors that have compressed the spinal cord, and ischemic injuries of the spinal cord. When traumatic injuries of the thoracic spinal cord occur, … Continue reading →

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Cerebral Palsy Symptoms, Causes, Treatment – What other …

Posted: Published on June 15th, 2015

What other conditions are associated with cerebral palsy? Since cerebral palsy is indicative of damage to or malformation of the brain, it stands to reason that other symptoms that are associated with brain dysfunction can be present in children afflicted with cerebral palsy. In fact other disorders, besides the motor dysfunctions already described, are almost always seen in these patients. Some of them such as poor speech, swallowing disorders, drooling, and poor fine or gross motor coordination are the result of the motor disorder affecting specific muscles involved in those functions. Other conditions are the results of simultaneous injuries in areas of the brain besides the motor areas. Cognitive disabilities, sometimes referred to as developmental delay, are often associated with cerebral palsy. Up to half of patients with cerebral palsy have cognitive disabilities. However, many of these children can be educated and lead productive lives. It is also just as important to note that many children with severe motor impairment due to cerebral palsy, as is the case with many children with the choreoathetotic or the diplegic form of cerebral palsy, are only mildly or not at all intellectually impaired. Virtually all testing of a young child's cognitive development involves … Continue reading →

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Anoxic Brain Injury | BrainAndSpinalCord.org

Posted: Published on June 15th, 2015

Adequate oxygen is vital for the brain. Many factors can cause the brain to receive inadequate oxygen. When oxygen levels are significantly low for four minutes or longer, brain cells begin to die and after five minutes permanent anoxic brain injury can occur. Anoxic brain injury which is also called cerebral hypoxia or hypoxic-anoxic injury (HAI) is a serious, life-threatening injury; it can cause cognitive problems and disabilities. Some HAI injuries are due to a partial lack of oxygen; the term hypoxic means partial lack. Other HAI injuries are due to a complete lack of oxygen; the term anoxic means total lack. The greater the loss of oxygen, the more wide-spread and serious the injury will be. The death of brain cells interrupts the brains electrochemical impulses and interferes with the performance of neurotransmittersthe chemical messengers which transmit messages within the brain. The neurotransmitters regulate body functions and influence behavior. For example, the neurotransmitters serotonin, dopamine, and norepinephrine help regulate moods, while the endorphins increase pleasure and control pain. The neurotransmitter acetylcholine plays an important role in memory. There are four types of anoxia, but each can cause the same serious damage to the brain. Usually HAI will begin with … Continue reading →

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Multiple Sclerosis. Medical information about MS | Patient

Posted: Published on June 15th, 2015

What is multiple sclerosis (MS)? MS is a disease where patches of inflammation occur in parts of the brain and/or spinal cord. This can cause damage to parts of the brain and lead to various symptoms (described below). Many thousands of nerve fibres transmit tiny electrical impulses (messages) between different parts of the brain and spinal cord. Each nerve fibre in the brain and spinal cord is surrounded by a protective sheath made from a substance called myelin. The myelin sheath acts like the insulation around an electrical wire, and is needed for the electrical impulses to travel correctly along the nerve fibre. Nerves are made up from many nerve fibres. Nerves come out of the brain and spinal cord and take messages to and from muscles, the skin, body organs and tissues. MS is thought to be an autoimmune disease. This means that cells of the immune system, which normally attack germs (bacteria, viruses, etc), attack part of the body. When the disease is active, parts of the immune system, mainly cells called T cells, attack the myelin sheath which surrounds the nerve fibres in the brain and spinal cord. This leads to small patches of inflammation. Something may … Continue reading →

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Think Twice Before Eating That Ham Sandwich Or Triple Meat …

Posted: Published on June 15th, 2015

(Before It's News) Unless you eat organic foods and prepare them at home, youve probably purchased packaged, processed meats at some time. Non-organic versions contain added preservatives, chemicals and GMOs; and, many harbor bacterial toxins that harm the body. Even their organic counterparts may be similarly contaminated during processing. Most processed meats are treated to stop the growth of molds and to prevent spoilage. Those that have not been chemically treated, such as organic meats, are still potential breeding grounds for unwelcome micro-organisms. Processed meat Fresh meat contains one ingredient, meat. Processed meats contain numerous ingredients, and not all are meat. Additives prolong shelf life, enhance flavors, stabilize colors, and inhibit bacterial growth.Processed meats include sliced deli meats, sausage, jerky, pepperoni, bacon, lunch meats, hot dogs, and meats used on pizzas, in canned foods, and in packaged products. Bacterial toxins Salmonella bacteriais common in processed meats. Organic meats are no exception. Consuming salmonella-contaminated foods can produce illness in the form of fever, vomiting, chills and severe diarrhea leading to dehydration and death in sensitive individuals. The primary form of transmission is through contaminated hands spreading bacteria during packaging. Washing hands thoroughly and sterilizing cooking surfaces and utensils help prevent contamination. … Continue reading →

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Cosmetic Surgery – Metairie, LA – New Orleans, LA – Dr …

Posted: Published on June 15th, 2015

Dr. Stephen Eric Metzingerwelcomes patients to our cosmetic surgery practice serving the greater New Orleans-Metairie, LAarea. We put your safety and well-being before anything else. We understand that pursuing cosmetic surgery is a personal and often emotional choice, so we work to provide an inviting, spa-like environment where you feel welcome and relaxed. Dr. Metzinger has nearly two decades of plastic surgery experience and is the only triple board-certified surgeon in New Orleans. He and our staff use some of the most advanced surgical techniques to provide outstanding results while minimizing scarring and recovery time. Whether you want to improve the look of your face, breasts, or body, Dr. Metzinger can create a customized surgical plan to help improve your appearance and self-esteem. To learn more about Dr. Metzinger and our practice, or to schedule a consultation, contact our office today. We opened our Metairie practice almost two decades ago in 1996. Our office is very close to the causeway with easy access to New Orleans. We are located three blocks from beautiful Lake Pontchartrain. We take several measures to improve your experience while you wait at our comfortable office. For example, our staff provides complimentary hot tea and iced … Continue reading →

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FDA Grants IND Approval for Phase IIa Clinical Trial Using …

Posted: Published on June 11th, 2015

Want to stay informed? Sign up for our email newsletter here SAN DIEGO and Epalinges, Switzerland June 9, 2015 Stemedica Cell Technologies, Inc. received the FDAs investigational new drug (IND) approval for a United States-based, Phase IIa clinical study using its allogeneic stem-cell therapy to treat subjects with mild to moderate dementia due to Alzheimers disease (AD), the sixth leading cause of death in the United States. The study is sponsored by Stemedica International, S.A. and will start at the University of California, San Diego (UCSD) under Principle Investigator Douglas Galasko, M.D. and expand to other sites. Stemedica International will provide management and financial support for this clinical trial. The clinical trial is titled "A Phase IIa Multicenter, Randomized, Single-blind, Placebo-controlled, Crossover Study to Assess the Safety, Tolerability, and Preliminary Efficacy of a Single Intravenous Dose of Allogeneic Human Mesenchymal Stem Cells in Subjects with Mild to Moderate Dementia Due to Alzheimer's Disease." This study was approved based on the excellent safety profile of Stemedicas cGMP-manufactured, hypoxically-grown stem cells and on solid pre-clinical data obtained by Stemedica International in cooperation with the cole Polytechnique Fdrale de Lausanne of Switzerland and with a grant from the Swiss government, said Lev Verkh, … Continue reading →

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Stem Cell Transplants – KidsHealth

Posted: Published on June 10th, 2015

Stem cells are cells in the body that have the potential to turn into anything, such as a skin cell, a liver cell, a brain cell, or a blood cell. Stem cells that turn into blood cells are called hematopoietic stem cells. These cells are capable of developing into the three types of blood cells: Hematopoietic stem cells can be found in bone marrow (the spongy tissue inside bones), the bloodstream, or the umbilical cord blood of newborn babies. A stem cell transplant (sometimes called a bone marrow transplant) can replenish a child's supply of healthy hematopoietic stem cells after they have been depleted. It's used to treat a wide range of diseases, including cancers like leukemia, lymphoma, neuroblastoma, Wilms tumor, and certain testicular or ovarian cancers; blood disorders; immune system diseases; and bone marrow syndromes. Transplanted hematopoietic stem cells are put into the bloodstream through an intravenous (IV) line, much like a blood transfusion. Once in the body, they can produce healthy new blood and immune system cells. The two main types of stem cell transplants are autologous and allogeneic. The type of transplant needed will depend on the child's specific medical condition and the availability of a matching … Continue reading →

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BioMarin Submits Drisapersen MAA to EMA for the Treatment …

Posted: Published on June 10th, 2015

SAN RAFAEL, Calif., Jun 08, 2015 (GLOBE NEWSWIRE via COMTEX) -- BioMarin Pharmaceutical Inc. BMRN, -2.62% announced today the submission of a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for drisapersen, an investigational antisense oligonucleotide drug candidate for the treatment of the largest subset of Duchenne muscular dystrophy (DMD) amenable to single exon skipping. DMD is the most common fatal genetic disorder diagnosed in childhood, affecting approximately 1 in every 3,500 live male births with about 20,000 new cases diagnosed globally each year. In Europe, it is estimated there are 23,000 boys with Duchenne Muscular Dystrophy, and approximately 3,000 of those would be candidates for drisapersen.In BioMarin's commercial territories, approximately 85 percent of Duchenne patients are located outside of the United States, including Western Europe, Middle East, Eastern Europe, Latin America and Japan. Western Europe has the largest patient population among those areas, exceeding the United States by around 30 percent. Drisapersen induces the skipping of dystrophin exon 51, potentially providing a therapeutic benefit to DMD patients for whom skipping of exon 51 restores the proper dystrophin reading frame, corresponding to approximately 13% of DMD patients. The company recently submitted a New Drug Application (NDA) to the … Continue reading →

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