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Cerebral Palsy: Symptoms & Treatment | Nervous System …

Posted: Published on June 10th, 2015

Overview Cerebral palsy is a group of disorders involving chronic impairment and control of bodily movement that usually first appear in the very young children. This disorder is caused by abnormal development or damage in one or more parts of the brain that control muscle tone and movement. Child with cerebral palsy has difficulty controlling and coordinating muscles. Very simple movements for that child are difficult. Other names for this disorder are a static encephalopathy, spastic diplegia, and "Littles disease,". It is caused by a permanent brain defect or an injury at birth or shortly thereafter. Causes of Cerebral palsy are birth complications, some compilcations during the pregnancy, and some complications after birth. In many cases, the exact cause of the Cerebral palsy is never known. There are four types of cerebral palsy - spastic cerebral palsy, athetoid cerebral palsy, ataxic cerebral palsy, and mixed cerebral palsy. Early signs include the delayed milestones such as controlling head, rolling over, sitting without support, crawling, or walking. Symptoms of Cerebral palsy could include spasticity, poor muscle tone, uncontrolled movements, and problems with posture, balance, coordination, walking, speech, swallowing, seizures, breathing problems, mental retardation, learning disabilitiesskeletal deformities, eating difficulties, dental problems, bladder and … Continue reading →

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Sodium picosulfate (Dulcolax Pico). Constipation …

Posted: Published on June 10th, 2015

About sodium picosulfate Type of medicine Stimulant laxative Used for Constipation and before some surgery or medical examinations Also called For constipation: Dulcolax Pico For before medical procedures: CitraFleet; Picolax Available as Capsules, oral solution, sachets of powder Constipation can be caused by a poor diet, not drinking enough water and not going to the toilet as soon as you feel you need to. Pregnancy, a lack of exercise or movement (such as being ill in bed) and some medicines, including some painkillers, can also cause constipation. However, many people take laxatives when they do not need to because they believe that they are constipated unless they go to the toilet every day. This is not the case. A useful definition of constipation is going to the toilet less frequently than is normal for you, and passing hard stools (poo) when you do go. Sodium picosulfate works by encouraging the muscles in your bowel to move waste products through your body. This helps you to go to the toilet. It usually has an effect within 6-12 hours. Sodium picosulfate preparations are available to buy without a prescription at pharmacies and other retail outlets. Preparations containing sodium picosulfate (in combination with … Continue reading →

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Femtomedicine Process Kills Cancer Cells, Protects Healthy …

Posted: Published on June 10th, 2015

Professor Qing-Bin Lu, from the University of Waterloos Faculty of Science, initiated a novel molecular-mechanism-based program to discover a new class of non-platinum-based-halogenated molecules that kill cancer cells, yet prevent healthy cells from being damaged. The most effective cancer drugs today may kill cancer cells, but they also kill healthy cells, causing severe side effects for patients in the process. Femtosecond time-resolved laser spectroscopy is a technique traditionally applied to study chemical reactions as they occur on a molecular level. The laser takes a series of rapid snapshots of molecules as they interact and change structure over time. The technique is part of a potential new field of science developed by Professor Lu called femtomedicine (FMD), which integrats the ultrafast laser with molecular biology and cell biology. Professor Lu has applied the tool to understand the molecular mechanisms that cause cancer at the very moment when the DNA becomes damaged. He has also used it to investigate how radiation therapy and chemotherapy using chemical agents, in particular the widely used platinum chemotherapeutic Cisplatin, work in treating a variety of cancers. We know DNA damage is the initial step, said Professor Lu. With the novel femtomedicine approach we can go back … Continue reading →

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Visualizing Light at Trillion FPS, Camera Culture, MIT …

Posted: Published on June 10th, 2015

Home|News|Join Us|People|Projects|Publications|Talks|Courses The device has been developed by the MIT Media Labs Camera Culture group in collaboration with Bawendi Lab in the Department of Chemistry at MIT. A laser pulse that lasts less than one trillionth of a second is used as a flash and the light returning from the scene is collected by a camera at a rate equivalent to roughly half a trillion frames per second. However, due to very short exposure times (roughly two trillionth of a second) and a narrow field of view of the camera, the video is captured over several minutes by repeated and periodic sampling. The new technique, which we call Femto Photography, consists of femtosecond laser illumination, picosecond-accurate detectors and mathematical reconstruction techniques. Our light source is a Titanium Sapphire laser that emits pulses at regular intervals every ~13 nanoseconds. These pulses illuminate the scene, and also trigger our picosecond accurate streak tube which captures the light returned from the scene. The streak camera has a reasonable field of view in horizontal direction but very narrow (roughly equivalent to one scan line) in vertical dimension. At every recording, we can only record a '1D movie' of this narrow field of view. In … Continue reading →

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Leukemia Stem Cell Transplantation | CTCA

Posted: Published on June 9th, 2015

What is stem cell transplantation? A stem cell transplant (also called hematopoietic progenitor cell transplantation) infuses healthy blood-forming stem cells into the body. Stem cells can be collected from the bone marrow, circulating (peripheral) blood, and umbilical cord blood. There are two main types of stem cell transplants: An advantage of an allogeneic transplant is that the stem cells come from a healthy donor with no malignant cells. However, since it can be difficult to find a matching donor, an autologous transplant is usually more common. A stem cell transplant can be used to restore healthy bone marrow in patients with leukemia. Stem cells help stimulate new bone marrow growth and restore the immune system. Before a stem cell transplant for leukemia, you will undergo a conditioning regimen, which involves intensive treatment to destroy as many leukemia cells as possible. You may receive high doses of chemotherapy and, in some cases, radiation therapy. You may also receive reduced-intensity conditioning (a mini-allogeneic transplant), which uses lower, less toxic doses of chemotherapy and/or total body irradiation (TBI) before the transplant. Once this preparative regimen is complete, you are ready to undergo the transplant. Much like a blood transfusion, youll receive the stem … Continue reading →

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Asterias Biotherapeutics Announces First Patient Treated …

Posted: Published on June 8th, 2015

MENLO PARK, Calif., June 8, 2015 /PRNewswire/ -- Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company focused on the emerging field of regenerative medicine, today announced that the first patient was successfully dosed at the Atlanta-based Shepherd Center in a Phase 1/2a clinical trial evaluating activity of escalating doses of AST-OPC1 (oligodendrocyte progenitor cells) in newly injured patients with sensory and motor complete cervical spinal cord injury (SCI). The Phase 1/2a trial is part of the planned registration program for AST-OPC1, with neurologically complete cervical SCI as the first targeted indication. The open-label, single-arm study, which will be conducted at a total of up to eight centers in the United States, will test three sequential escalating doses of AST-OPC1 administered at up to 20 million AST-OPC1 cells in 13 patients with sub-acute, C-5 to C-7, neurologically complete cervical SCI. These individuals have essentially lost all sensation and movement below their injury site with severe paralysis of the upper and lower limbs. AST-OPC1 will be administered 14 to 30 days post-injury. Patients will be followed by neurological exams and imaging methods to assess the safety and activity of the product. Additional information on the Phase 1/2a study, including trial sites, … Continue reading →

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Recovery of sensory function by stem cell transplants

Posted: Published on June 8th, 2015

New research from Uppsala University shows promising progress in the use of stem cells for treatment of spinal cord injury. The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions. Traffic accidents and severe falls can cause ruptures of nerve fibers that enter/exit the spinal cord. Most commonly, these avulsion injuries affect the innervation of the arm and hand, and lead to paralysis, loss of sensation and cause chronic pain. Surgical interventions can help the patient regain some muscle function, but there is currently no treatment able to restore sensory functions. The reason for this is the emergence of a "barrier" at the junction between the ruptured nerve fibers and the spinal cord which prevents them from growing into the spinal cord and restore lost nerve connections. In a new study the PhD students Jan Hoeber, Niclas Knig and Carl Trolle, working in Dr.Elena Kozlova's research group transplanted human stem cells to an avulsion injury in mice with the aim to restore a functional route for sensory information from peripheral tissues into the spinal cord. The results show that … Continue reading →

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Cerebral Palsy: Treatment & Care | Nervous System …

Posted: Published on June 6th, 2015

Table of Contents Cerebral palsy is a term used to describe a specific group of chronic conditions affecting body movements and muscle coordination. These conditions are all caused by the damage to one or more specific areas of the brain, usually occurring during fetal development, but it can also happen during the first few months after birth. The level of disorder ranges from mild to severe. Physical symptoms of cerebral palsy are weakness and floppiness of muscles or spasticity and rigidity in most cases, but it can also be accompanied with mental retardation or seizures. The worse thing about this condition is that it cannot be cured. Depending on what part of the brain is affected, a child might not be able to walk, talk, eat, or play. Brain is a large organ and almost any part of it can be affected and thus children may experience a wide variety of signs and symptoms, ranging from mild to severe. The most common are: There are three major types of cerebral palsy: Spastic cerebral palsy Most children with cerebral palsy have spastic cerebral palsy. This form of the condition causes muscles to stiffen, which makes movement difficult. It can affect both … Continue reading →

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Q Therapeutics Announces FDA Clearance of Its Stem Cell …

Posted: Published on June 5th, 2015

You may also like.... Kadimastem To Initiate a Human Clinical Trial for Promising ALS Therapy FDA Controversy Over ALS Drug Trial Highlights Urgent Need For Further Research ALS Study Shows Benefits of NurOwn Stem Cell Therapy Q Therapeutics, Inc., a company focused on adult stem cell therapies for disorders of the central nervous system, recently announced that its product Q-Cells has received Investigational New Drug (IND) clearance by the U.S. Food and Drug Administration (FDA) for the start of Phase 1/2a clinical trials in humans to evaluate the safety and tolerability of Q-Cells in patients with amyotrophic lateral sclerosis (ALS). ALS is a progressive neurodegenerative disease, characterized by the gradual degeneration and atrophy of motor neurons in the brain and spinal cord that are responsible for controlling essential voluntary muscles, such as the ones related to movement, speaking, eating, and even breathing. ALS patients may become totally paralyzed and the majority dies due to respiratory failure within two to five years after diagnosis. It is estimated that more than 300,000 Americans suffer from the diseaseforwhichthere is currently no cure. Q-Cells corresponds to a cell-based therapeutic product candidate designed to preserve or restore the normal neural activity. It is based on … Continue reading →

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Stem Cell Therapy | South Florida Orthopedic Surgery

Posted: Published on June 4th, 2015

Home > Stem Cell Therapy Call us for more information 561-368-1880 Source: Research by Tim Friend and Dan Vergano, USA TODAY By Frank Pompa and Julie Snider, USA TODAY Although the general public considers stem cell therapy an innovative, cutting-edge treatment, the fact is that this kind of therapy already has a lengthy history. In the past, however, stem cells were difficult and very expensive to obtain. Luckily, the advent of improved equipment and techniques has meant that stem cells can now be acquired through a simple procedure. Stem cells can be characterized as the bodys repairmen. The most common type is the hematopoietic stem cell (HSC-CD 34+). The old thinking was that the hematopoietic stem cells were not that important. We now know that these are the cells that are the true drivers of tissue regeneration. The good news about these cells is that their numbers do not diminish with age. The other type of stem cell associated with tissue healing is the mesenchymal stem cell (MSC), which usually travels to injured areas of the body via the bloodstream. The mesenchymal stem cell is still a very important stem cell but not as important as it once was. It … Continue reading →

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