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Stem Cell Transplant – National Cancer Institute

Posted: Published on May 30th, 2015

What are bone marrow and hematopoietic stem cells? Bone marrow is the soft, sponge-like material found inside bones. It contains immature cells known as hematopoietic or blood-forming stem cells. (Hematopoietic stem cells are different from embryonic stem cells. Embryonic stem cells can develop into every type of cell in the body.) Hematopoietic stem cells divide to form more blood-forming stem cells, or they mature into one of three types of blood cells: white blood cells, which fight infection; red blood cells, which carry oxygen; and platelets, which help the blood to clot. Most hematopoietic stem cells are found in the bone marrow, but some cells, called peripheral blood stem cells (PBSCs), are found in the bloodstream. Blood in the umbilical cord also contains hematopoietic stem cells. Cells from any of these sources can be used in transplants. What are bone marrow transplantation and peripheral blood stem cell transplantation? Bone marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) are procedures that restore stem cells that have been destroyed by high doses of chemotherapy and/or radiation therapy. There are three types of transplants: Why are BMT and PBSCT used in cancer treatment? One reason BMT and PBSCT are used in … Continue reading →

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BTS Bioengineering | Home

Posted: Published on May 30th, 2015

Information pursuant to Legislative decree N. 196/2003 on protection of Privacy In compliance with current laws, we would like to inform you that in accordance with Legislative Decree n.196 of 30 June 2003 (and subsequent amendments) the data you provide shall be processed always taking into account the obligations and in compliance with the laws indicated above. Pursuant to article 4, paragraph 1, letter A, of Legislative Decree n. 196 of 30 June 2003 (commonly referred to as the Privacy Code) processing shall be considered as: any operation or set of operations which is performed upon personal data, whether or not by automatic means, such as collection, recording, organization, storage, adaptation or alteration, retrieval, consultation, use, disclosure by transmission, dissemination or otherwise making available, alignment or combination, blocking, erasure or destruction. Data controller The data controller of the data you provide is BTS S.p.A. with headquarters in viale Forlanini 40, 20024 Garbagnate Milanese (MI). Purposes of the processing In accordance with Legislative Decree n. 196 of 30 October 2004, we would like to inform you that by filling out and submitting this form the following will be accepted: The data collected by means of this form shall be used by … Continue reading →

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Stem Cell Therapy for Neuromuscular Diseases | InTechOpen

Posted: Published on May 30th, 2015

1. Introduction Neuromuscular disease is a very broad term that encompasses many diseases and aliments that either directly, via intrinsic muscle pathology, or indirectly, via nerve pathology, impair the functioning of the muscles. Neuromuscular diseases affect the muscles and/or their nervous control and lead to problems with movement. Many are genetic; sometimes, an immune system disorder can cause them. As they have no cure, the aim of clinical treatment is to improve symptoms, increase mobility and lengthen life. Some of them affect the anterior horn cell, and are classified as acquired (e.g. poliomyelitis) and hereditary (e.g. spinal muscular atrophy) diseases. SMA is a genetic disease that attacks nerve cells, called motor neurons, in the spinal cord. As a consequence of the lost of the neurons, muscles weakness becomes to be evident, affecting walking, crawling, breathing, swallowing and head and neck control. Neuropathies affect the peripheral nerve and are divided into demyelinating (e.g. leucodystrophies) and axonal (e.g. porphyria) diseases. Charcot-Marie-Tooth (CMT) is the most frequent hereditary form among the neuropathies and its characterized by a wide range of symptoms so that CMT-1a is classified as demyelinating and CMT-2 as axonal (Marchesi & Pareyson, 2010). Defects in neuromuscular junctions cause infantile and … Continue reading →

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Bioengineering – Temple University

Posted: Published on May 29th, 2015

Temple University's Bioengineering Department offers students access to the merging worlds of engineering and biological sciences. Bioengineering at Temple University Bioengineers graduating from our program will be individuals with a solid foundation in not only engineering but also physical and life sciences. Students and researchers going through our department will acquire a strong sense about translational biomedical research as well. Our students and trainees will be exposed to both basic and applied knowledge from diverse areas of engineering and sciences, such as thermodynamics, biomechanics, bioinformatics, bioimaging, bioprocessing, fluid mechanics, polymer chemistry, biomaterials, and cellular, molecular and regenerative engineering. This knowledge will enable our graduates to join and lead interdisciplinary teams of engineers, scientists and clinicians to solve fundamental problems in the world around us. These problems include the design of innovative smart biomaterials, tissue constructs, medical devices and diagnostic technologies,and other areas that improve the quality of global health care and the standard of living throughout the world. Temple's Bioengineering Department has a strong focus in understanding human biology and associated diseases and injuries to ultimately invent engineering solutions to improve our status quo. Please refer to our undergraduate and graduate program websites (accessible in the left column and below) … Continue reading →

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autism treatment – WebMD

Posted: Published on May 28th, 2015

IMAGES PROVIDED BY: (1) Vicky Leon/Vetta (2) Nicholas Eveleigh/Iconica (3) Jamie Grill/Blend Images (4) Adam Gault/OJO Images (5) John Lund, Nevada Weir/Blend Images (6) ISM/Phototake (7) Johner Images (8) Steven van Soldt/Vetta (9) Blue Mountain Images/Flickr (10) Annabella Bluesky/Photo Researchers (11) Michael Hitoshi/Riser (12) Victoria Yee/Photographer's Choice (13) Burger, PHAINE/Photo Researchers (14) Steve Pomberg/WebMD (15) Stephen St. John/National Geographic (16) Ariel Skelly/The Agency Collection (17) Paul Mansfield Photography/Flickr Select (18) Datacraft Co Ltd (19) Tom Grill/Photographer's Choice RF (20) Don Smith/Flickr (21) Aaron C Photography/Flickr (22) BananaStock (23) ImagesBazaar REFERENCES: AHEADD: "About Us." American Family Physician: "Speech and Language Delay: What Does This Mean for My Child?" Association for Science in Autism Treatment: "Is Autism on the Rise?" Autism Genome Project: "About the AGP." Autism Society: "About Autism," "Causes," "Related Conditions," "Medical Diagnosis," "Asperger's Syndrome," "Related Conditions," "Environmental Health Initiative," "Educational Mandates," "Placement," "Transitions." Autism Speaks: "What is Autism?" "Symptoms," "New Imaging Techniques Shed Light on Autism," "Diagnosis," "Asperger Syndrome," "Frequently Asked Questions," "Applied Behavior Analysis," "Your Child's Rights," "Assistive Technology." The Center for Autism Spectrum Disorders at Binghamton University: "About Autism and ASD." Centers for Disease Control and Prevention: "Autism Spectrum Disorders," "Autism Spectrum Disorders: Signs and Symptoms," "Autism … Continue reading →

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Ulcerative colitis | University of Maryland Medical Center

Posted: Published on May 28th, 2015

Description An in-depth report on the causes, diagnosis, treatment, and prevention of ulcerative colitis. Inflammatory bowel disease - ulcerative colitis; Colitis - ulcerative Ulcerative Colitis Ulcerative colitis and Crohn's disease are inflammatory bowel diseases. All inflammatory bowel diseases cause chronic inflammation in the digestive system. Ulcerative colitis occurs only in the inner lining of the large intestine whereas Crohn's disease extends into deeper areas of the intestinal wall and can affect any part of the gastrointestinal tract (digestive system). Causes and Risk Factors The exact causes of ulcerative colitis are unknown. Genetics plays some role. Between 10 - 20% of people with ulcerative colitis have family members with the disease. Ulcerative colitis is diagnosed most often in people ages 15 - 35. Ulcerative colitis is more common among whites than people of other races. Jewish people of Eastern European (Ashkenazi) descent have a higher than average risk for developing this disease. Link: Ulcerative colitis | University of Maryland Medical Center … Continue reading →

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Ulcerative Colitis Symptoms, Causes, Treatment – What are …

Posted: Published on May 28th, 2015

What causes ulcerative colitis? The cause of ulcerative colitis is not known. To date, there has been no convincing evidence that it is caused by infection or is contagious. Ulcerative colitis likely involves abnormal activation of the immune system in the intestines. The immune system is composed of immune cells and the proteins that these cells produce. These cells and proteins serve to defend the body against harmful bacteria, viruses, fungi, and other foreign invaders. Activation of the immune system causes inflammation within the tissues where the activation occurs. (Inflammation is, in fact, an important mechanism of defense used by the immune system.) Normally, the immune system is activated only when the body is exposed to harmful invaders. In patients with ulcerative colitis, however, the immune system is abnormally and chronically activated in the absence of any known invader. The continued abnormal activation of the immune system causes chronic inflammation and ulceration. The susceptibility to abnormal activation of the immune system is genetically inherited. First degree relatives (brothers, sisters, children, and parents) of patients with IBD are thus more likely to develop these diseases. There have been multiple studies using genome wide association scans investigating genetic susceptibility in ulcerative colitis. … Continue reading →

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Life After Brain Injuries: Are We Still the Same People …

Posted: Published on May 28th, 2015

Biology 202 2002 Second Paper On Serendip During the summer of my junior year, a friend of mine, we will call her "Jen", got into a horrible car accident. Apparently sitting in the middle of the backseat, only strapped in with a lap belt, my friend hit her head on the side window, smashing the window upon impact. After 3 weeks of being in a coma, my friend eventually recovered. Even though she was deemed "physically" healed, my friend was truly never the same. Not only had her demeanor and interests changed, but also it seemed as if she had become a completely different person after her accident. I thought it very sad at the time, because the friends who had been close to her before were no longer close. I did not understand what they meant when they said that she had become a different person. Certainly, I realized that she had changed, but I could not fathom that she was now so different that they could no longer treat her like the old "Jen". I believed that this new "Jen" was still the same person as before-that the inner soul with which they had become friends had never … Continue reading →

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Marx Biotechnology A disruptive technology that saves …

Posted: Published on May 27th, 2015

A disruptive technology that saves lives and improves patient care Main menu Marx Biotechnology is developing a proprietary first-in-class molecular diagnostic kit for the early detection of Graft versus Host Disease (GVHD). GVHD is a life threatening complication of allogeneic (non-self) stem cell transplantation such as bone marrow, peripheral blood or cord blood transplantation and solid organ transplantations. The cells from the donor react adversely to the cells in the patient. GVHD affects approximately 50% of all such transplant patients, frequently resulting in death. https://www.youtube.com/watch?v=c_8PcfZSkrI Marx Bios approach has 5 clear advantages: Incorporated in Jerusalem in January 2011, the Marx Bio team has completed proof of concept in animal studies, has published in a peer reviewed journal, and has filed three patents. It is commencing a Phase 1 clinical trial in humans in Tel Aviv. Marx Bio has a clear work schedule to deliver a validated and cleared product, ready for market entry within 36 to 48 months. The company is looking for strategic partners to join in that journey. Originally posted here: Marx Biotechnology A disruptive technology that saves ... … Continue reading →

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Life After Traumatic Brain Injury | My true-life story …

Posted: Published on May 25th, 2015

Balance Bike Ridden by Child Wearing Helmet Everyone, parent or not, knows that kids fall. My son ran headlong into doors, fell off tables, and even hit the floor when I fell down the stairs carrying him. (Thats a long storyIll try to get to it later) But did you know how many Brain Injuries (BIs) are caused by falls? In the Nov. 13 New England Journal of Medicine, the results of a study of more than 43,000 children led by Dr. Nathan Kuppermann, a professor in the departments of emergency medicine and pediatrics at the University of California, Davis School of Medicine were published. The leading cause of BIs for children, individuals under the age of 18, was falls. Dr. Nathan Kuppermann For parents, the numbers can be frightening: under 2 years of age, 77% of BI are the result of falls. Seventy-seven! I dont know if thats a reassuring factMaybe there arent that many BIs in infants and newborns. For children between 2 and 12, the number is cut by half, and is only 38 percent. For children between age 13-17, the leading causes of BI were assaults, sports, and car crashes. Over recent years, we have seen … Continue reading →

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