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Cardior Announces CE Marking of CardiorHealth miR-132 PCR Kit Used in Ongoing HF-REVERT Phase 2 Clinical Study – Business Wire

Posted: Published on September 12th, 2022

HANOVER, Germany--(BUSINESS WIRE)--Cardior Pharmaceuticals, a clinical-stage biotech company developing non-coding RNA (ncRNA)-based therapeutics for patients with cardiac diseases, today announced the CE marking of its PCR kit which measures circulating microRNA-132 (miR-132) levels in the blood of patients receiving the companys lead candidate CDR132L, an oligonucleotide-based miR-132 inhibitor. The company is currently conducting its Phase 2 clinical study, HF-REVERT (NCT05350969), to evaluate the safety and efficacy of CDR132L in patients with heart failure and reduced left ventricular ejection fraction (LVEF) after a myocardial infarction. By using the CardiorHealth miR-132 PCR kit, Cardior ensures consistent measurement of miR-132 levels following CDR132L treatment across all clinical trial centers as an indicator of the target engagement and the compounds mechanism of action. Continue reading

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Treatment | Parkinson’s Foundation

Posted: Published on September 12th, 2022

There is no one-size-fits all treatment for Parkinsons. Rather, treatment should be tailored to an individuals symptoms via a shared decision-making process with your healthcare provider Continue reading

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Medical Marijuana | Parkinson’s Foundation

Posted: Published on September 12th, 2022

With medical marijuana now legalized in 38 states and the District of Columbia, there is strong interest in its therapeutic properties. Researchers are testing marijuana, which is also called cannabis, as a treatment for many illnesses and diseases, including Parkinson's disease (PD). Continue reading

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Parkinson’s disease: etiopathogenesis and treatment – PubMed

Posted: Published on September 12th, 2022

The concept of 'idiopathic' Parkinson's disease (PD) as a single entity has been challenged with the identification of several clinical subtypes, pathogenic genes and putative causative environmental agents. In addition to classic motor symptoms, non-motor manifestations (such as rapid eye movement sleep disorder, anosmia, constipation and depression) appear at prodromic/premotor stage and evolve, along with cognitive impairment and dysautonomia, as the disease progresses, often dominating the advanced stages of the disease. The key molecular pathogenic mechanisms include -synuclein misfolding and aggregation, mitochondrial dysfunction, impairment of protein clearance (associated with deficient ubiquitin-proteasome and autophagy-lysosomal systems), neuroinflammation and oxidative stress. Continue reading

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Wolff-Parkinson-White Syndrome (WPW) – Cleveland Clinic

Posted: Published on September 12th, 2022

Overview Wolff-Parkinson-White Syndrome - Patrick Tchou, MD What is Wolff-Parkinson-White Syndrome (WPW)? Normally, the heartbeat begins at the sinoatrial (SA) node, located in your right atrium. Continue reading

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IMAC Holdings, Inc. Announces Completion of Third Cohort of its Phase 1 Clinical Study of Umbilical Cord-Derived Mesenchymal Stem Cells for the…

Posted: Published on September 12th, 2022

IMAC Holdings, Inc. BRENTWOOD, Tenn., Sept Continue reading

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CuraSen Therapeutics Announces First Patients Treated with Novel Combination Therapy (CST-2032/CST-107) in Phase 2a Study of Mild Cognitive Impairment…

Posted: Published on September 12th, 2022

SAN CARLOS, Calif.--(BUSINESS WIRE)--CuraSen Therapeutics, Inc., a clinical-stage company developing small molecule therapies to treat neurodegenerative disease, announced that it has begun dosing patients in a Phase 2a clinical trial with CST-2032, a novel, oral beta-2 adrenoceptor (2-AR) agonist. The goal of the study is to evaluate the effects of CST-2032 on cognition and mood in patients with mild cognitive impairment or mild dementia due to either Parkinsons or Alzheimers disease. CST-2032 is administered in combination with CST-107, a -AR blocker, to minimize known side effects of 2-AR agonists. Continue reading

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Ohio Valley Team Hope Walk to raise awareness of Huntingtons Disease – Hamilton Journal News

Posted: Published on September 12th, 2022

Its not a run, its a walk. Its really a fun event Continue reading

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Neuroplast receives second orphan medicinal product designation for Neuro-Cells, paving the way for application to both chronic and trauma-induced…

Posted: Published on September 12th, 2022

Fast-track status is granted for frontotemporal dementia, next to the existing designation for traumatic spinal cord injury GELEEN, Netherlands, Sept. Continue reading

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US$ 70M AdventHealth Training Center opens in Florida – Construction Review

Posted: Published on September 12th, 2022

A ribbon-cutting event was held recently for a US$70 million AdventHealth Training Center in Central Florida. The newly built facility is a collaboration between the non-profit AdventHealth, the DeVos family, and the Orlando Magic basketball team. In addition to providing a training site for Orlando Magic, the facility will also serve as a sports medicine hub. Continue reading

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