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UCLA Research Shows Promising Method For Correcting Genetic Code To Treat Sickle Cell Disease

Posted: Published on March 14th, 2015

Posted: Thursday, March 12, 2015 7:08 PM UCLA stem-cell researchers have shown that a novel stem-cell gene therapy method could one day provide a one-time, lasting treatment for the most common inherited blood disorder in the U.S. sickle cell disease. Publishedin the journal Blood, the study outlines a method that corrects the mutated gene that causes sickle cell disease and shows, for the first time, the gene correction method leads to the production of normal red blood cells. The study was directed by renowned stem cell researcher and UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member, Dr. Donald Kohn. People with sickle cell disease are born with a mutation in their beta-globin gene, which is responsible for delivering oxygen to the body through blood circulation. The mutation causes blood stem cellswhich are made in the bone marrowto produce distorted and rigid red blood cells that resemble a crescent or sickle shape. Consequently, the abnormally shaped red blood cells do not move smoothly through blood vessels, resulting in insufficient oxygen supply to vital organs. Anyone can be born with sickle cell disease, but it occurs more frequently in African Americans and Hispanic Americans. The stem-cell … Continue reading

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Milan resident with rare disease reaches out to community for help

Posted: Published on March 13th, 2015

By Joyce Ervin Special to The Milan News-Leader Pictured is a photograph of Danielle Peladeaus daughters, Jocelyn and Rachel on the GoFundMe website. Peladeau is raising funds for a stem cell transplant. She is a sufferer of the rare disease, Stiff Person Syndrome. As a suffer of the rare disease Stiff Person Syndrome, she finds herself now raising funds for herself to help pay for a stem cell transplant her insurance wont completely cover through the online non-profit GoFundMe. A rare disease is any disease that has fewer than 200,000 people diagnosed worldwide. There are only 300 people in the United States diagnosed with Stiff Person Syndrome Peladeau said, Unfortunately, it is progressive and there is no cure like many other diseases such as Amyotrophic lateral sclerosis also known as Lou Gehrig disease and Lupus, said Peladeau. Peladeau had to wait a long time to be considered a candidate for the treatment that her hematologist recommended that will take place in Chicago. In spite of the difficult logistics, Peladeau decided to go ahead with the transplant. She will remain there for six to eight weeks and it is recommended a caregiver stay with her for the entire time. She would … Continue reading

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A4M Fellowship in Aesthetic Medicine @ IMA Dubai – Dr. Gordon Ku – Video

Posted: Published on March 13th, 2015

A4M Fellowship in Aesthetic Medicine @ IMA Dubai - Dr. Gordon Ku A4M Fellowship in Aesthetic Medicine @ IMA Dubai - Dr. Gordon Ku. By: Institute of Medical Aesthetics … Continue reading

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Aesthetic Surgery Growing In Popularity, But Not For The Reasons Many People Think

Posted: Published on March 13th, 2015

OWINGS MILLS, Md., March 13, 2015 /PRNewswire-USNewswire/ -- The term "mommy make-over" may conjure images of tummy tucks and butt lifts, but for many women suffering from genital abnormalities, congenital conditions of the genitalia, sexual dysfunction, as well as female urologic conditions such as pelvic prolapse and incontinence, a "mommy make-over" in terms of female genital aesthetic surgery is life-changing. Dr. Karen Boyle of Chesapeake Urology Associates and Chesapeake Aesthetic Surgery Center, has helped restore the intimate appearance, self-confidence and sexual function of countless women through genital aesthetic surgery. Dr. Boyle is one of the country's leading male and female sexual health and aesthetic surgery experts and performs the specialized aesthetic surgical procedures for women, and men, to not only restore intimate appearance but sexual gratification and function as well. What makes Dr. Boyle unique among aesthetic surgeons is her extensive training and experience in urology, sexual health and microsurgery. Because of this training, she not only understands the cosmetic side of aesthetic surgery but also how to ensure that a woman's sexual function is preserved, restored and/or enhanced. Aesthetic Surgery for Women on the Rise Aesthetic surgery is becoming more popular as more women seek to enhance and refine … Continue reading

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'Ever-evolving' sense of beauty: Plastic surgery trends for men and women both

Posted: Published on March 13th, 2015

The vanity business appears is flourishing. The American Society for Aesthetic Plastic Surgery announced Thursday that Americans spent over $12 billion on assorted procedures in 2014. One sector is on the increase. More men are turning to aesthetic cosmetic procedures, with dramatic increases seen in both surgical and nonsurgical options over the past 5 years and a 43 percent increase overall, the organization stated. There were over 10 million cosmetic procedures performed last year - with the greatest increase in buttock augmentation, up by 86 percent - along with labiaplasty (up 49 percent), and nonsurgical fat reduction, which has increased by 43 percent. For those who need an explanation, labiaplasty is contouring of distinctly female body parts. The group has previously cited this procedure as a global trend and places it in the category of ever-evolving concept of beauty. Meanwhile, liposuction, breast augmentation, eyelid surgery, tummy tucks and nose surgery - all longtime fixtures in the field - are the top five procedures for men and women overall. But men have their favorites. Blepharoplasty - an eyelid, lift, essentially - plus male breast reduction and facelifts are the top three procedures. Since the organization began collecting statistical data in 1997, … Continue reading

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DNA Editing of Human Embryos Alarms Scientists

Posted: Published on March 13th, 2015

A call by scientists to halt to precision gene-editing of DNA in human embryos would allow time to work out safety and ethical issues Sperm cell fertilizing an egg. Credit: Wikimedia Commons Amid rumors that precision gene-editing techniques have been used to modify the DNA of human embryos, researchers have called for a moratorium on the use of the technology in reproductive cells. In a Comment published on March 12 inNature, Edward Lanphier, chairman of the Alliance for Regenerative Medicine in Washington DC, and four co-authors call on scientists to agree not to modify human embryos even for research. Such research could be exploited for non-therapeutic modifications. We are concerned that a public outcry about such an ethical breach could hinder a promising area of therapeutic development, write Lanphier and his colleagues, who include Fyodor Urnov, a pioneer in gene-editing techniques and scientist at Sangamo BioSciences in Richmond, California. Many groups, including Urnov's company, are already using gene-editing tools to develop therapies that correct genetic defects in people (such as by editing white blood cells). They fear that attempts to produce designer babies by applying the methods to embryos will create a backlash against all use of the technology. Known … Continue reading

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Meet the miracle triplets – born two years apart

Posted: Published on March 13th, 2015

They are the miracle triplets - born two years apart. Ethan, Isabel and Arthur Preston were all conceived at the same time. But Isabel and Arthur were born in December - two years and five days after Ethan. Parents Katie and Matthew are looking forward to celebrating their first Mother's Day with the trio on Sunday. All three siblings were conceived while the couple, from Castle Vale, underwent IVF treatment at Midland Fertility. "They are our three little miracles," said Katie, a cashier at William Hill. "December is a busy time for the Preston family now - but we wouldn't have it any other way. "They keep me busy, and are certainly a handful. But we feel complete and adore our triplets. Katie and Matthew, both 28, tried for a family for five years before discovering they only had a one per cent chance of conceiving as Matthew has a low sperm count. "I would see a woman with a pram in the street and would go home and cry," admits Katie. "Many of my family and friends were having families, and we just thought it would never happen for us. View post: Meet the miracle triplets - born two … Continue reading

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Class 12 -Biology-Genetics-Lec5-Human Blood Group Genetics – Video

Posted: Published on March 13th, 2015

Class 12 -Biology-Genetics-Lec5-Human Blood Group Genetics Covers genetics of human blood group system along with precautions for safe blood transfusion and disesase Erythroblastosis Featalis. By: sci4you … Continue reading

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Genetics Problems Based on Mendel’s Laws – Sex Linkage – Video

Posted: Published on March 13th, 2015

Genetics Problems Based on Mendel's Laws - Sex Linkage Learn about Mendel's Laws and Sex Linkage through genetics problems, such as red-green color blindness and dimple inheritance. By: Elon TLT … Continue reading

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Sin city genetics – Video

Posted: Published on March 13th, 2015

Sin city genetics Getting ready to go into a three gallon pot. By: (RMC)rockymountaincultivators … Continue reading

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