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Experts in congenital heart disease in children and adults will discuss challenges

Posted: Published on March 10th, 2015

Many aspects of pediatric cardiology are relatively new to the discipline. Only recently have physicians been able to accurately diagnose and characterize the myriad congenital cardiovascular conditions that occur and begin to apply successful strategies for care. This week, an international group of more than 800 medical experts gather at the nation's largest pediatric cardiology conference to discuss challenges in treating congenital heart disease in the fetus, neonates, children and young adults. Affecting one in 120 children, congenital heart disease (CHD) is the most common birth defect, which in the most severe forms is also the leading cause of death in infants and young children. "While the origins of congenital heart disease remain a mystery, diagnostic capabilities continue to improve, and treatment and management strategies continue to evolve. However, many anomalies remain difficult to treat effectively," said Jack Rychik, M.D., the conference course director and medical director of the Fetal Heart Program and the Single Ventricle Survivorship Program at The Children's Hospital of Philadelphia. He added, "as a consequence of our success, the survivors of childhood surgery and other treatments are now adults, presenting to us with new needs. Early survival alone is not sufficient. The challenge ahead is to … Continue reading

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New Heart Drug From Novartis: Will It Raise The Risk of Alzheimer’s Disease?

Posted: Published on March 10th, 2015

LCZ696 is a heart failure drug from Novartis that many observers think will gain FDA approval later this year and go on to become a blockbuster. Perhapsthe biggest obstacle to the drugs success is the fear that it might raise the risk of Alzheimers disease. Now a new article in a top cardiology journal lays out the detailed basis for this concern. The authors donot contend that the Alzheimers issue will likely ruin the drugs chances, but they do maintain that the problem needs to be carefully monitored. I spoke with Milton Packer, the co-principal investigator of PARADIGM-HF, the mega trial that set off the mega excitement about the drug last year. He offers several persuasive arguments that Alzheimers disease wont bethe Achilles heel of LCZ696. But first lets look at the paper, published in theEuropean Heart Journal, by a group of French researchers. The paper focuses on the potential impact of sacubitril, which is one of the two key ingredients of LCZ696. Sacubitril inhibits the action of neprilysin. The French authors focus on two conflicting roles for neprilysin.The cardiovascular benefitsare achieved because in the heart neprilysin inhibition leads to increased levels of neuropeptides and vasodilators that are beneficial in … Continue reading

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The BecA-ILRI Hub and its contribution to African agricultural biotechnology and crop improvement – Video

Posted: Published on March 10th, 2015

The BecA-ILRI Hub and its contribution to African agricultural biotechnology and crop improvement 5th International Conference on Next Generation Genomics and Integrated Breeding for Crop Improvement February 18-20, 2015 ICRISAT, Patancheru, India The Bec... By: KSIConnect … Continue reading

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Entrepreneurship In Biotechnology — For Everyone

Posted: Published on March 10th, 2015

Time to put the class Entrepreneurship in Biotechnology online. Topic number one: why everyone everyone should study entrepreneurship. Only a small percentage of us will ever start a business. So why should we all study entrepreneurship? Well, what is entrepreneurship? Yes, it is the process by which we start businesses. It Is also the means by which we express creativity in a business setting. Most importantly, it is the way we take our ideas, our observations that there are problems in the world that we think we can fix, and make those ideas into something tangible, a product or a process or a service that can benefit others. Some of my students discover that entrepreneurship is something more. To them, entrepreneurship is freedom, the freedom that comes from knowing that regardless of the job market, the economy, or the opportunities for advancement in your workplace you have the option to create your own future, your own path, in your own way. Just knowing that you have that capacity is liberating. Why? Well, what is the first rule of negotiation? Have options. Knowing how to start a business means you always have an option. The perspective entrepreneur is never trapped or … Continue reading

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Potential toxicity of cellulose nanocrystals examined in Industrial Biotechnology journal

Posted: Published on March 10th, 2015

IMAGE:Industrial Biotechnology, led by Co-Editors-in-Chief Larry Walker, PhD, Biological and Environmental Engineering Department, Cornell University, Ithaca, NY, and Glenn Nedwin, PhD, MoT, CEO and President, Taxon Biosciences, Tiburon, CA, is... view more Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, February 19, 2015--Novel nanomaterials derived from cellulose have many promising industrial applications, are biobased and biodegradable, and can be produced at relatively low cost. Their potential toxicity--whether ingested, inhaled, on contact with the skin, or on exposure to cells within the body--is a topic of intense discussion, and the latest evidence and insights on cellulose nanocrystal toxicity are presented in a Review article in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Industrial Biotechnology website. Maren Roman, PhD, Virginia Tech, Blacksburg, VA, describes the preparation of cellulose nanocrystals (CNCs) and highlights the key factors that are an essential part of studies to assess the potential adverse health effects of CNCs by various types of exposure. In the article "Toxicity of Cellulose Nanocrystals: A Review" , Dr. Roman discusses the current literature on the pulmonary, oral, dermal, and cytotoxicity of CNCs, provides an in-depth view on their effects on human health, … Continue reading

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Bruce Lipton DNA Activation New Biology Belief E5 – Video

Posted: Published on March 10th, 2015

Bruce Lipton DNA Activation New Biology Belief E5 Trending Now: Lindsey Williams Elite Opec and Bilderberg Illuminati Oil Price Predictions NWO Conspiracy https://www.youtube.com/watch?v=4xdu22K7Xv8 Updated: Mar... By: Alien History Chronicles … Continue reading

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Bruce Lipton DNA Activation New Biology Belief E8 – Video

Posted: Published on March 10th, 2015

Bruce Lipton DNA Activation New Biology Belief E8 Trending Now: Lindsey Williams Elite Opec and Bilderberg Illuminati Oil Price Predictions NWO Conspiracy https://www.youtube.com/watch?v=4xdu22K7Xv8 Updated: Mar... By: Alien History Chronicles … Continue reading

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Bruce Lipton DNA Activation New Biology Belief E4 – Video

Posted: Published on March 10th, 2015

Bruce Lipton DNA Activation New Biology Belief E4 Trending Now: Lindsey Williams Elite Opec and Bilderberg Illuminati Oil Price Predictions NWO Conspiracy https://www.youtube.com/watch?v=4xdu22K7Xv8 Updated: Mar... By: Alien History Chronicles … Continue reading

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Bruce Lipton DNA Activation New Biology Belief E11 – Video

Posted: Published on March 10th, 2015

Bruce Lipton DNA Activation New Biology Belief E11 Trending Now: Lindsey Williams Elite Opec and Bilderberg Illuminati Oil Price Predictions NWO Conspiracy https://www.youtube.com/watch?v=4xdu22K7Xv8 Updated: Mar... By: Alien History Chronicles … Continue reading

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Bruce Lipton DNA Activation New Biology Belief E9 – Video

Posted: Published on March 10th, 2015

Bruce Lipton DNA Activation New Biology Belief E9 Trending Now: Lindsey Williams Elite Opec and Bilderberg Illuminati Oil Price Predictions NWO Conspiracy https://www.youtube.com/watch?v=4xdu22K7Xv8 Updated: Mar... By: Alien History Chronicles … Continue reading

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