Research and educational centres, working in the field of bioinformatics, should focus on envisaging ambitious projects with implications in the application-related fields such as agriculture, public health, environment and several others, said Alok Bhattacharya, Task Force Chairman at Department of Biotechnology (DBT). Interacting with the audience during the inaugural of 26th BTISnet Annual Coordinators Meeting at Sri Venkateswara University (SVU) here on Tuesday, Dr. Bhattacharya urged the participants to think big by coming out of their comfort zones and chart out a path for ambitious projects. Bioinformatics, in the country, has come a long way promoting biological sciences along with its developments. Various centres related to Bioinformatics should come together, by forming clusters, and embark on projects which will change the way, he added. Dr. Bhattacharya further emphasised on setting up a centralised database to store the research data and maintained that the Super Computer Infrastructure, soon to be set up at a cost of Rs.4,500 crore, would help the research to a great extent. Please Wait while comments are loading... 1. Comments will be moderated by The Hindu editorial team. 2. Comments that are abusive, personal, incendiary or irrelevant cannot be published. 3. Please write complete sentences. Do not … Continue reading →

Wilmington, DE (PRWEB) February 03, 2015 The European Bioinformatics Institute (EMBL-EBI) has released version 20 of ChEMBL, the database of compound bioactivity data and drug targets. ChEMBL now incorporates the Hierarchical Editing Language for Macromolecules (HELM), the macromolecular representation standard recently released by the Pistoia Alliance. HELM can be used to represent simple macromolecules (e.g. oligonucleotides, peptides and antibodies) complex entities (e.g. those with unnatural amino acids) or conjugated species (e.g. antibody-drug conjugates). Including the HELM notation for ChEMBLs peptide-derived drugs and compounds will, in future, enable researchers to query that content in new ways, for example in sequence- and chemistry-based searches. Initially created at Pfizer, HELM was released as an open standard with an accompanying toolkit through a Pistoia Alliance initiative, funded and supported by its member organisations. EMBL-EBI joins the growing list of HELM adopters and contributors, which include Biovia, ACD Labs, Arxspan, Biomax, BMS, ChemAxon, eMolecules, GSK, Lundbeck, Merck, NextMove, Novartis, Pfizer, Roche, and Scilligence. All of these organisations have either built HELM-based infrastructure, enabled HELM import/export in their tools, initiated projects for the incorporation of HELM into their workflows, published content in HELM format, or supplied funding or in-kind contributions to the HELM project. Bridging the … Continue reading →