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Report from ACTRIMS/ECTRIMS Part I – Video

Posted: Published on January 20th, 2015

Report from ACTRIMS/ECTRIMS Part I The Report from ACTRIMS/ECTRIMS, Part I webcast reviews the abstracts presented at ACTRIMS/ECTRIMS that have the most critical clinical implications in the a... By: ClevelandClinicCME … Continue reading →

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MS Centre receives donation from Freemasons

Posted: Published on January 20th, 2015

From left, Mike Newcombe, Terri McDonald, Brian Herbert, MS Centre member Nick Weeks, Norman Weeks and Bill Bishop. FREEMASONS have donated 1,000 to the West of England MS Therapy Centre in Bradley Stoke. Members of the Gloucester Masonic charity Action presented the money to Terri McDonald, head of fundraising at the centre in Wheatfield Drive. Charity steward Mike Newcombe, director of ceremonies Bill Bishop, secretary Brian Herbert, master Norman Weeks and Peter Acton from the local Lodge of St Christopher 9095 visited the centre to find out how it provides treatment and therapy for people with multiple sclerosis (MS). Ms McDonald said: "We certainly are in need of support, especially in our physiotherapy department. A person with MS can delay the symptoms and other neurological conditions by having regular physiotherapy exercise classes. "If a muscle is not used for long periods, it will lose strength and may become painful. "These difficulties cannot always be avoided completely. However, by finding the right exercises, with the assistance of our qualified physiotherapists in neurology, the person with MS can remain active and lead an independent life for longer." The centre receives no Government or NHS funding and relies solely on donations from trusts, … Continue reading →

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'Revenge' matriarch enlists in MS battle

Posted: Published on January 20th, 2015

As Victoria Grayson on ABCs Revenge, Madeleine Stowe plays a ruthless matriarch. Off the screen, TV villainy can translate into good works. Stowe is using her celebrity to raise awareness about multiple sclerosis and drawing on memories of her late fathers battle against the disease. Its really important that people communicate with each other, that caregivers communicate, said Stowe, 56. Ask questions: What does it feel like? Do not isolate. Thats crucial. She will take part in Lights, Camera, Take Action on MS at 11 a.m. Saturday at the Hilton Orlando, 6001 Destination Parkway (the event is free; register at takeactionms.com). Stowe has partnered with Genzyme, part of the Sanofi health-care company. She is a paid spokesman for Genzyme and she said she donates the money to a group that deals with health and human dignity issues. She doesnt discuss treatment options for MS, a disease of the central nervous system that can be disabling. I talk about my own personal experience, what its like to be a family member, to reach out to neighbors, to create a support system, she said. Her father, a civil engineer for the state of California, lived with MS for about 20 years before … Continue reading →

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New dad Jason Manford donates baby’s umbilical cord and placenta for stem cell research – Video

Posted: Published on January 20th, 2015

New dad Jason Manford donates baby's umbilical cord and placenta for stem cell research Comic Jason Manford has revealed he and his girlfriend have donated their new baby's umbilical cord and placenta for stem cell research. Lucy Dyke, 35, gave ... By: Wali Ullah … Continue reading →

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Jeunesse Global Product Science and Stem Cell Research – Video

Posted: Published on January 20th, 2015

Jeunesse Global Product Science and Stem Cell Research http://jeunessesystem.com - Learn what the makes the Jeunesse products so revolutionary with stem cell technology and formulations backed by proven science. By: Jeunesse System … Continue reading →

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Twist1: Complex regulator of cell shape and function

Posted: Published on January 20th, 2015

These results, published in the journal "Cell Reports", help to unravel seemingly contradictory observations and illuminate the complexities of transcription factor action in regeneration and tumor progression. Team leader Christina Scheel summarizes the results: "Twist1 is a developmental master regulator that has also been implicated in cancer progression. We show that transient Twist1 activation primes certain cells for stem-cell-like properties and cellular plasticity. Said differently, induction of these traits depends on Twist1, but they are only displayed by the cells after Twist1 deactivation. By contrast, chronic Twist1 activity suppresses stem-cell-like properties and promotes a phenotype that is characterized by extreme changes in cell shape and function, effectively locking the cells into an invasive, non-proliferative phenotype. Thereby, our results provide an integrative view of seemingly contradictory results concerning the effects of Twist1 in physiological and pathological processes." Duration of Twist1 activity decisive Scientists from the Institute of Stem Cell Research and the Institute of Experimental Genetics at the Helmholtz Zentrum Mnchen (HMGU) examined the effects of Twist1 activation on breast epithelial cells, paying particular attention to the duration of the Twist1-signal. To their surprise, cells were permanently altered after a short dose of Twist1-activation: they proliferated under very stringent conditions usually … Continue reading →

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Twist1: Complex regulator of cell shape, function

Posted: Published on January 20th, 2015

These results, published in the journal Cell Reports, help to unravel seemingly contradictory observations and illuminate the complexities of transcription factor action in regeneration and tumor progression. Team leader Christina Scheel summarizes the results: "Twist1 is a developmental master regulator that has also been implicated in cancer progression. We show that transient Twist1 activation primes certain cells for stem-cell-like properties and cellular plasticity. Said differently, induction of these traits depends on Twist1, but they are only displayed by the cells after Twist1 deactivation. By contrast, chronic Twist1 activity suppresses stem-cell-like properties and promotes a phenotype that is characterized by extreme changes in cell shape and function, effectively locking the cells into an invasive, non-proliferative phenotype. Thereby, our results provide an integrative view of seemingly contradictory results concerning the effects of Twist1 in physiological and pathological processes." Duration of Twist1 activity decisive Scientists from the Institute of Stem Cell Research and the Institute of Experimental Genetics at the Helmholtz Zentrum Mnchen (HMGU) examined the effects of Twist1 activation on breast epithelial cells, paying particular attention to the duration of the Twist1-signal. To their surprise, cells were permanently altered after a short dose of Twist1-activation: they proliferated under very stringent conditions usually … Continue reading →

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Louis-Jeantet-Prize for Medicine goes to Emmanuelle Charpentier

Posted: Published on January 20th, 2015

Award honors fundamental research that is expected to be of considerable significance for medicine IMAGE:This is professor Emmanuelle Charpentier, recipient of the Louis-Jeantet-Prize for Medicine 2015. view more Credit: Helmholtz / Hallbauer&Fioretti Prof Emmanuelle Charpentier from the Helmholtz Centre for Infection Research (HZI) in Braunschweig is one of the two recipients of the 2015 Louis-Jeantet-Prize for Medicine. The prize money of 700,000 Swiss francs is mostly attributed for the continuation of the awardees work. Charpentier receives the prize for harnessing an ancient immune defense system in bacteria - CRISPR-Cas9 - into a genome editing tool largely exploited by biologists and promising for curing human diseases. Bacterial pathogens also possess an immune system that defends them against predators, and particularly viruses. When studying this system, Charpentier while she was a group leader at the Laboratory for Molecular Infection Medicine Sweden (MIMS) at Ume University and her team unravelled a unique mechanism - CRISPR-Cas9 - a pair of molecular scissors composed of a duplex of two RNAs linked to a protein. In collaboration with the team of her colleague Prof Jennifer Doudna, University of California, Berkeley, it was demonstrated that the mechanism could be harnessed into a powerful tool for genome engineering. … Continue reading →

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Dartmouth study sheds light on genetic mutations in autism disorders

Posted: Published on January 20th, 2015

IMAGE:Bryan Luikart, an assistant professor of Physiology and Neurobiology in the Geisel School of Medicine at Dartmouth, leads a research team investigating the neurobiological basis of autism spectrum disorders. view more Credit: Dartmouth College HANOVER, N.H. - Recent research has linked autism with a lack of "pruning" in developing brain connections, but a new Dartmouth study suggests instead it is the excessive growth of new connections that causes sensory overload in people with the disorder. The results, which have broad implications for understanding the neurobiological basis of autism spectrum disorders, appear in The Journal of Neuroscience. A PDF of the study is available on request. "We've been working on understanding how dysfunction of the gene Pten, which is known to cause some cases of autism, effects neuronal development, and I believe our findings represent the best understanding in science today for how an autism candidate gene changes the functional characteristics of developing neurons," says senior author Bryan Luikart, an assistant professor of Physiology and Neurobiology in the Geisel School of Medicine at Dartmouth. Mutations in the gene Pten are among the most common single-gene mutations that cause autism and a group of interrelated syndromes. People with these diseases have increased … Continue reading →

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Stem Cell Therapy | Recent Strides Quell Stem Cell Debate – Video

Posted: Published on January 20th, 2015

Stem Cell Therapy | Recent Strides Quell Stem Cell Debate Ethical concerns for stem cells for arthritis could be mute...maybe. Reports show that adult stem cells (Autologous) have been shown in recent studies to have significant effects on osteoarthritis... By: Nathan Wei … Continue reading →

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