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This news release is available in German. In the majority of cases, the onset of cancer is characterised by a minor change in a person's genetic material. A cell's DNA mutates in a particular area to the extent that the cell no longer divides in a controlled manner, but begins to grow uncontrollably. In many cases, this type of genetic mutation involves chemical changes to individual building blocks of DNA. These changes are induced by smoking tobacco and consuming foods such as cured meats. This is because the contents of these materials can chemically react with and change building blocks of cellular DNA, thereby creating DNA adducts. Up to now, scientists have been able to determine whether gene samples contain adducts and if so, how many. However, the procedure is laborious and finding out exactly where a building block in the genetic code has been altered into an adduct has not been possible. Researchers from the team led by Shana Sturla, professor of Food and Nutrition Toxicology, have succeeded for the first time in amplifying gene samples containing DNA adducts while retaining references to these adducts. This type of amplification is a prerequisite for the majority of technologies used by … Continue reading →

There were no witnesses to the gruesome murder of a South Carolina mother and her 3-year-old daughter inside a busy apartment complex four years ago. But a new technology that can create an image of someone using DNA samples left at crime scenes might bring police closer to catching the killer. Reston, Va.-based Parabon Nanolabs, with funding from the Department of Defense, has debuted a breakthrough type of analysis called DNA phenotyping which the company says can predict a person's physical appearance from the tiniest DNA samples, like a speck of blood or strand of hair. The DNA phenotyping service, commercially known as "Snapshot," could put a face on millions of unsolved cases, including international ones, andgenerate investigative leads when the trail has gone cold. "This is particularly useful when there are no witnesses, no hits in the DNA database and nothing to go on," Dr. Ellen McRae Greytak, Parabon's director of bioinformatics, told FoxNews.com. - Dr. Ellen McRae Greytak, Parabon Nanolabs "Traditional forensic analysis treats DNA as a fingerprint, whereas Snapshot treats it as a blueprint -- a genetic description of a person from which physical appearance can be inferred," Greytak said. Parabon's new technology reads the parts of … Continue reading →