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Most cases of cancer down to bad luck rather than lifestyle or inherited genes

Posted: Published on January 2nd, 2015

Pancreatic cancer cells dividing. Random mutations in DNA are behind two thirds of adult cancers, a study says. Photograph: Visuals Unlimited, Inc./Dr. Stan/Getty Images/Visuals Unlimited Most cases of cancer are largely the result of bad luck rather than unhealthy lifestyles, diet or inherited genes, new research suggests. Random mutations that occur in DNA when cells divide are largely responsible for two thirds of adult cancers across a wide range of tissues. The remaining third are linked to environmental factors or defective inherited genes. But the scientists warn that poor lifestyle can add to the bad luck factor involved in cancer. The researchers analysed published data on the number of divisions of self-renewing stem cells that occur in an average lifetime in 31 different tissues. These results were compared with the lifetime incidence of cancer in the same tissues. A strong correlation was seen between a particular tissues stem cell division rate and its likelihood of developing cancer. The more often cells divide, the more likely it is that letters of their genetic code will become jumbled, leading to an increased cancer risk. Overall, the study found that random mutations due to stem cell division could largely explain around 65% of … Continue reading →

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Trace your Welsh DNA at Scarlets v Ospreys game

Posted: Published on January 2nd, 2015

How would your Welsh Ancestry look? HAVE you ever wondered where your ancestors came from? As part of a new TV series, DNA Cymru,people in Llanelli are being given the chance to trace their geneticroots. The team will be at Parc y Scarlets on Saturday ahead of the Ospreys clash offering more information about the project and giving people the chance to win a freeAncestral DNA testing kit. Series producer Angela Graham of Green Bay Media explains, We are attempting an unprecedented mass survey of Welsh DNA to throw light on movements of population in the past and find answers to some historical puzzles. Two of S4Cs DNA Cymrupresenters, Beti George and Dr Anwen Jones, will be at Parc y Scarlets to help explain some of the questions through the testing of ancestral DNA. The series, which airs on S4C onMarch 1,presents the journey of humanity from its origins in Africa to the earliest populations of the land we now know as Wales, right up the inhabitants of todays Wales. In the series, presenters Beti George, Dr Anwen Jones and Jason Mohammad will be explaining how the science of DNA can reveal genetic blueprints that stretch back beyond recorded history. … Continue reading →

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Killing for DNA: A predatory device in the cholera bacterium

Posted: Published on January 2nd, 2015

Cholera is caused when the bacterium Vibrio cholerae infects the small intestine. The disease is characterized by acute watery diarrhea resulting in severe dehydration. EPFL scientists have now demonstrated that V. cholerae uses a tiny spear to stab and kill neighboring bacteria -- even of its own kind -- and then steal their DNA. This mechanism, known as "horizontal gene transfer," allows the cholera bacterium to become more virulent by absorbing the traits of its prey. The study is published in Science. The lab of Melanie Blokesch at EPFL has uncovered how V. cholerae uses a predatory killing device to compete with surrounding bacteria and steal their DNA. This molecular killing device a spring-loaded spear that is constantly shooting out. This weapon is called the "type VI secretion system" (T6SS) and is known to exist in many types of bacteria. When V. cholerae comes close to other bacteria, the spear punches a hole into them, leaving them to die and release their genetic material, which the predator pulls into itself. Killing neighbors and stealing genes This spear-killing, predatory behavior is triggered by the bacterium's environment. The cholera bacterium naturally lives in water, such as the sea, where it attaches onto … Continue reading →

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Oxidation of Copper | Metals | Chemistry – Video

Posted: Published on January 2nd, 2015

Oxidation of Copper | Metals | Chemistry The video shows the oxidation of copper. When copper is heated in a flame, it loses its characteristic reddish brown colour. This is due to a chemical reaction between the copper and the oxygen... By: KClassScienceChannel … Continue reading →

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Introduction to Chemistry Professor – Video

Posted: Published on January 2nd, 2015

Introduction to Chemistry Professor By: Chemistry Professor … Continue reading →

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Alia Bhatt & Arjun Kapoor Hot Chemistry in 2 States – Video

Posted: Published on January 2nd, 2015

Alia Bhatt Arjun Kapoor Hot Chemistry in 2 States While many speculated that these two were an item, 2 States exposed their love story way too hot with steamy kisses hitting back to backA young, live-in love affair is all that we got to... By: Bollywood Uncut Hot … Continue reading →

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Chemistry project- can all water conduct electricity? – Video

Posted: Published on January 2nd, 2015

Chemistry project- can all water conduct electricity? By: Tori Lief … Continue reading →

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Mondo Rock reunite for first tour in 24 years

Posted: Published on January 2nd, 2015

Young and restless ... Mondo Rock in the early days. Mondo Rock are getting back together for their first tour in 24 years to perform their Chemistry album live. Chemistry, released in 1981, was the Australian rockers second album and reached No.3 on the charts. Mondo Rock were originally formed in 1976 by ex-Daddy Cool singer-songwriter Ross Wilson. Getting back together with the original Chemistry era Mondo Rock members, I imagine, is like when war veterans get back together, you had to be there, no one else understands kind of thing, said Wilson, 66. And then when we do reunite, well raise all kinds of musical hell. Advertisement The album Chemistry produced the hits State Of The Heart, Cool World, Chemistry and Summer of 81. State of the Heart, written by Eric McCusker, also reached No.22 in the US in 1985 for Rick Springfield, who performed the song at the historic Live Aid concert. The 2014 Mondo Rock line-up will feature original members Ross Wilson, Eric McCusker, James Black and Paul Christie and The Aztecs drummer Gil Matthews. Tickets for the tour go on sale from February 21. Read the original: Mondo Rock reunite for first tour in 24 years … Continue reading →

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Abhishek Varman: Alia Bhatt and Arjun Kapoor have great chemistry

Posted: Published on January 2nd, 2015

Abhishek Varman has said that Alia Bhatt and Arjun Kapoor share "great chemistry" on screen. "I think both actors are incredibly talented, as shown by some of their past projects, and they interpreted the characters from the book perfectly," shared Varman. "It's also an added bonus that they have great chemistry together, as that's not something you can guarantee until you begin filming." Varman makes his directorial debut with 2 States, having previously assisted on My Name Is Khan, Jodhaa Akbar and Humko Deewana Kar Gaye. Speaking about his first film as a director, he said: "I've worked with Karan Johar on a number of other projects, as his Associate Director, and so he initially approached me, asking me what I thought of the project. I was immediately excited by the prospect. Based on Chetan Bhagat's book of the same name, the novelist recently joined Bhatt and Kapoor in London for the film's red carpet premiere. 2 States releases in cinemas on April 18. Watch the trailer below: Read this article: Abhishek Varman: Alia Bhatt and Arjun Kapoor have great chemistry … Continue reading →

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More efficient, sensitive estrogen detection developed at UT Arlington

Posted: Published on January 2nd, 2015

IMAGE:This is Kevin Schug, Shimadzu Distinguished Professor of Analytical Chemistry at UT Arlington. view more Credit: UT Arlington Scientists at the Shimadzu Institute for Research Technologies and the Department of Chemistry and Biochemistry at The University of Texas at Arlington have collaborated to develop a new method for detecting trace amounts of estrogen in small samples that holds the potential to improve research into cancer and other diseases. The hormone estrogen plays an important role in the human body and has been linked to everything from tumor growth to neuron loss during Alzheimer's disease. But detecting very small amounts of it in blood and other biological fluids can be difficult for health researchers, especially in the limited amounts available in laboratory experiments. In response, a UT Arlington research team applied advanced mass spectrometry and chromatography instrumentation available at the Shimadzu Institute to develop a sensitive and efficient method for detecting trace amounts at less than 10 parts per trillion in a 100 microliter sample, said Kevin Schug, Shimadzu Distinguished Professor of Analytical Chemistry at UT Arlington. One part per trillion is the equivalent of a drop of water in 20 Olympic-size swimming pools. "This new method pushes the detection limit … Continue reading →

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