The "patch" has long been an aid for people who are trying to kick the habit. But now, it is also helping a girl with a rare genetic disorder. A 5-year-old girl with a rare form of epilepsy is now living virtually seizure-free, thanks to an unusual treatment. After exhausting all other options, doctors at a Florida hospital discovered that a tiny dose of nicotine, administered through a commercially available nicotine patch, was just enough to do the trick. 5-year-old Karen Macon has energy to spare, but that wasn't always the case. "She'd wake up tired every morning with dark circles under her eyes," says Annie Macon, Karens mother. Doctors diagnosed Karen with a rare genetic form of epilepsy called autosomal dominant nocturnal frontal lobe epilepsy. "Every single night, she was having an average of 20 seizures," says Ki Hyeong Lee, medical director for the epilepsy program at Florida Hospital for Children. "We tried probably seven different anti-convulsive medications and none of them worked, adds Macon. Dr. Lee says Karens genetic mutation appears to be linked to a nicotine deficiency in the body. Dr. Lee also found evidence that a nicotine patch helped stopped seizures in an adult with the … Continue reading →

Autism Treatment Third Eye Technologies Third Eye technologies has recently announced a major breakthrough and the first effective treatment for Autism Phobias, jointly with Newcastle University the treatment was published in the... By: Third Eye Technologies … Continue reading →

Risperidone Systematic (IUPAC) name 4-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)- 1-piperidyl]ethyl]-3-methyl- 2,6-diazabicyclo[4.4.0]deca-1,3-dien-5-one Clinical data Trade names Risperdal,Risperdal Consta,Risperdal M-Tab,Risperdal Quicklets AHFS/Drugs.com monograph MedlinePlus a694015 Pregnancy cat. Legal status Routes Oral (tablets and liquid form), IM Pharmacokinetic data Bioavailability 70% (oral)[1] Metabolism Hepatic (CYP2D6 mediated to 9-hydroxyrisperidone)[1] Half-life 20 hours (Oral), 2.96 days (IM) [1] Excretion Urinary (70% (adults), 4.3% (children), 7.4% (adolescents)), faecal (14%) [1] Identifiers CAS number 106266-06-2Y ATC code N05AX08 PubChem CID 5073 IUPHAR ligand 96 DrugBank DB00734 ChemSpider 4895Y UNII L6UH7ZF8HCY KEGG D00426Y ChEBI CHEBI:8871Y ChEMBL CHEMBL85Y Chemical data Formula C23H27FN4O2 Mol. mass 410.485 g/mol Cc1c(c(=O)n2c(n1)CCCC2)CCN3CCC(CC3)c4c5ccc(cc5on4)F Y(what is this?)(verify) Risperidone (// ri-SPAIR-i-dohn) (trade name Risperdal, and generics) is an antipsychotic drug mainly used to treat schizophrenia (including adolescent schizophrenia), schizoaffective disorder, the mixed and manic states of bipolar disorder, and irritability in people with autism. Risperidone is a second-generation atypical antipsychotic.[2] It is a dopamine antagonist possessing anti-serotonergic, anti-adrenergic and anti-histaminergic properties. Adverse effects of risperidone include significant weight gain and metabolic problems such as diabetes mellitus type 2,[3] as well as tardive dyskinesia and neuroleptic malignant syndrome. Risperidone and other antipsychotics also increase the risk of death in people with dementia.[4] The drug was developed by Janssen-Cilag, subsidiary of Johnson & … Continue reading →

(HealthDay News) -- Brain inflammation, triggered by an overactive immune system, is common among people with autism, a new study finds. However, this inflammation does not cause the developmental disorder. Rather, it's a response to the different factors that can trigger autism, the researchers stressed. Their findings are based on autopsies performed on 72 brains of people with and without autism. In the brains of those who had autism when they were alive, a certain type of cell had its genes for inflammation permanently turned on. "There are many different ways of getting autism, but we found that they all have the same downstream effect," study author Dan Arking, an associate professor at the Institute for Genetic Medicine at Johns Hopkins University School of Medicine in Baltimore, said in a university news release. "What we don't know is whether this immune response is making things better in the short term and worse in the long term," he added. The next step is to find out whether treating this inflammation would reduce symptoms of autism, Arking said. The study was published online Dec. 10 in the journal Nature Communications. "This type of inflammation is not well understood, but it highlights the … Continue reading →

INSANELY EXPLOSIVE RACE IN THE SKY Part 1 Race and accidents everyone laughs Race and accidents everyone laughsstroke warning signs, stroke symptoms, stroke volume, stroke prevention, stroke recovery, stroke treatment, stroke... By: dragon … Continue reading →