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Stroke – Overview – Mayo Clinic

Posted: Published on December 2nd, 2014

Clinical Trial at Mayo Clinic Saves Workaholic after Stroke If you are experiencing stroke symptoms, getting to a highly specialized treatment center that can quickly diagnose and deliver individualized treatment can have a dramatic impact on your outcome. Mayo Clinic's stroke experts, part of the nation's leading neurosciences program, provide comprehensive care for more than 20,000 people with stroke and other blood vessel and brain (cerebrovascular) conditions each year. On all campuses, Mayo Clinic exceeds the national average in the percentage of stroke patients who receive the appropriate, customized treatment, thereby optimizing outcomes. A stroke occurs when the blood supply to part of your brain is interrupted or severely reduced, depriving brain tissue of oxygen and nutrients. Within minutes, brain cells begin to die. A stroke is a medical emergency. Prompt treatment is crucial and early action can minimize brain damage and potential complications. Mayo Clinic's world-renowned stroke teams include doctors trained in blood vessel and brain conditions (cerebrovascular neurologists), brain blood vessel imaging (endovascular surgical neuroradiologists), blood vessel brain surgery (vascular neurosurgeons), physical medicine and rehabilitation (physiatrists), emergency medicine, and other subspecialists who work together to provide exactly the care you need. Having all this expertise in a single … Continue reading

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Stroke units improving but 'must do better'

Posted: Published on December 2nd, 2014

SPECIALIST stroke units in the North-East still have scope to improve, according to a major state of the nation report by experts. Two reports published by the Sentinel Stroke National Audit Programme (SSNAP) show that despite steady progress in the care of stroke patients in the UK there are still major shortages of both nurses and doctors. This is worrying because research shows that death rates are low when stroke wards have higher number of nurses and death rates for acutely ill patients are lower when there are more doctors available at nights and at weekends. The assessment of stroke care is commissioned by NHS England and run by a specialist unit of the Royal College of Physicians. The headline results based on the care provided to 74,000 patients between April 2013 to March 2014 - found that stroke care was improving, mainly due to reorganisation which established fewer but more specialist stroke units. But because the standards of care set by the SSNAP are very high it meant that many hospitals have received low scores. A spokesman for the SSNAP said this does not mean that local stroke services are unsafe but it does mean that many hospitals need … Continue reading

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Three hours made all the difference in a Fairchance womans recovery from stroke

Posted: Published on December 2nd, 2014

The average life expectancy in America is 78.8 years, or more than 690,000 hours, according to government statistics. But when it comes to stroke, three hours are all that matter. For Carolyn Hoover, those three critical hours occurred the day after Thanksgiving: Nov. 23, 2012. That evening, the Fairchance woman (then age 47) and her husband, Jon, had just finished dinner and were washing the dishes when Carolyn suddenly had to sit down. She couldnt speak. She couldnt see. She was unresponsive. She was just sitting at the table, wringing her hands, and when I looked at her, she just had this blank look on her face, Jon recalls. I didnt have a clue what was going on until the ambulance got there. The paramedics said she was having a stroke and that if she got treatment within three hours it could reduce some of the effects or reverse them. With stroke, time is brain. Every second a stroke persists hastens the death of brain cells and the loss of physical functioning that accompanies this process. So its critical to recognize stroke symptoms and seek immediate medical attention, as the Hoovers did. Sadly, though, many people ignore the signs of … Continue reading

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Researchers Identify Chemical Compound That Decreases Effects of Multiple Sclerosis

Posted: Published on December 2nd, 2014

UC Riverside-led mouse study shows the ligand indazole chloride improves motor function, imparting therapeutic benefits even when treatment is initiated at the peak of disease By Iqbal Pittalwala on December 1, 2014 Seema Tiwari-Woodruff is an associate professor of biomedical sciences at the UC Riverside School of Medicine. Photo credit: I. Pittalwala, UC Riverside. RIVERSIDE, Calif. Multiple sclerosis (MS), an autoimmune disease of the brain and spinal cord, affects about 2.3 million people worldwide (400,000 in the United States). Affecting more women than men, it can be seen at any age, although it is most commonly diagnosed between the ages of 20 and 40. An unpredictable disease that disrupts the flow of information within the brain and between the brain and the body, MS is triggered when the immune system attacks the myelin sheath, the protective covering around the axons of nerve fibers. The demyelination that follows causes a disruption of nerve impulses. As the protective sheath best imagined as the insulating material around an electrical wire wears off, the nerve signals slow down or stop, and the patients vision, sensation and use of limbs get impaired. Permanent paralysis can result when the nerve fibers are completely damaged by the … Continue reading

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Neurosurgeon shares Lasker-DeBakey Award for pioneering work on Parkinson disease treatment

Posted: Published on December 2nd, 2014

PUBLIC RELEASE DATE: 1-Dec-2014 Contact: Connie Hughes Connie.Hughes@wolterskluwer.com 646-674-6348 Wolters Kluwer Health @WKHealth December 1, 2014 - French neurosurgeon Alim Louis Benabid and American neurologist Mahlon DeLong were recently named winners of the 2014 Lasker-DeBakey Clinical Medical Research Award for their roles in developing deep brain stimulation (DBS) for the treatment of Parkinson disease. The December issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, includes a special tribute to Dr. Benabid, the first neurosurgeon to receive this prestigious award. Neurosurgery is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. Drs. Benabid and DeLong are honored for groundbreaking research in developing DBS--a nondestructive form of neuromodulation therapy that has improved motor function and quality of life for thousands of patients with Parkinson disease. "The discovery and adoption of DBS has ushered in a new era of restorative neurosurgery," according to a cover essay by Dr. Ashwin Viswanathan of Baylor College of Medicine, Houston, and colleagues. Recognition for Critical Research Leading to DBS for Parkinson Disease Dr. DeLong performed early research identifying the brain areas involved in motor dysfunction in Parkinson disease. In a pivotal 1990 study in monkeys with an experimental form of Parkinsonism, … Continue reading

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Impact of traumatic brain injury on longterm memory explored

Posted: Published on December 2nd, 2014

Date: December 1, 2014 Source: Kessler Foundation Summary: A new article provides insight into the variable impact of traumatic brain injury on long-term memory. Memory impairment affects 54% to 84% of individuals with TBI. While the variable impact of TBI on long-term memory has been recognized, the underlying cognitive mechanisms have not been detailed in this population. This variability in impairment among individuals with comparable injuries has been explained, in part, by the theory of cognitive reserve, i.e., higher intellectual enrichment confers a protective effect on long-term memory. To test the role of working memory in the protective effect of cognitive reserve on long-term memory, scientists evaluated 50 patients with moderate to severe TBI for working memory, long-term memory and cognitive reserve. Kessler Foundation researchers have authored a new article that provides insight into the variable impact of traumatic brain injury (TBI) on long-term memory. The article, "Working memory capacity links cognitive reserve with long-term memory in moderate to severe TBI: a translational approach," was epublished ahead of print on October 7 in the Journal of Neurology. The authors are Joshua Sandry, PhD, John DeLuca, PhD, and Nancy Chiaravalloti, PhD, of Kessler Foundation. Memory impairment affects 54% to 84% of … Continue reading

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Imaging Studies Differentiate PTSD & Mild Brain Injury

Posted: Published on December 2nd, 2014

By Rick Nauert PhD Senior News Editor Reviewed by John M. Grohol, Psy.D. on December 2, 2014 New research suggests advanced brain imaging techniques can help to differentiate military veterans with post-traumatic stress disorder (PTSD) from those with mild traumatic brain injury (MTBI). Currently, it is difficult for clinicians to make a definitive diagnosis as symptoms for PTSD and MTBI are similar, and the conditions are unable to be detected by normal structural neuroimaging. Emerging technology using hybrid imaging with positron emission tomography and computed tomography (PET/CT) in the pituitary region of the brain suggests a new method to distinguish the two conditions. The findings also lend support to the theory that many veterans diagnosed with PTSD may actually have hormonal irregularities due to pituitary gland damage from blast injury. The new study was presented at the annual meeting of the Radiological Society of North America (RSNA). MTBI involves damage to the brain from an external force, while PTSD is generally defined as a mental health condition that can develop after someone has experienced a traumatic event. Research has shown that up to 44 percent of returning veterans with MTBI and loss of consciousness also meet the criteria for PTSD. … Continue reading

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New hope for MS sufferers: Drug shown to alleviate symptoms in mice

Posted: Published on December 2nd, 2014

Researchers are zeroing in on what looks like an effective treatment for the symptoms of Multiple Sclerosis. Teams from UC Riverside and New York's Rockefeller University have both used the same compound, indazole chloride, to successfully reverse the progression of MS in mice. The drug appears to be able to stimulate the regeneration of the myelin sheath the nerve pathway coating that is progressively destroyed as MS attacks the nervous system. MS affects around 400,000 people in the United States alone, and some 2.5 million around the world, according to Healthline. It's a debilitating disease in which the body's immune system begins to attack its own nervous system, gradually breaking down the protective cover called the myelin sheath, which coats the axons of nerve fibers in the brain and spinal cord. As this demyelination progresses, patients begin to slowly experience the breakdown of their nervous system sensation, vision and motor control begin to slowly degenerate, and permanent paralysis can be the end result. It's a horrible sentence. One well known quirk of the disease is that female sufferers seem to have a reversal of their MS symptoms during the third trimester of pregnancy. This reversal has them feeling great for … Continue reading

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Researchers Make Breakthrough Discovery Paving Way For New MS Treatments

Posted: Published on December 2nd, 2014

By C. Rajan, contributing writer Researchers at the National University of Singapore (NUS) have discovered a new type of immune cells that play an important role in multiple sclerosis (MS) and other inflammatory diseases, thus providing a new avenue for therapies for these diseases. The multi-disciplinary research team led by Professor Xin-Yuan Fu, Senior Principal Investigator from CSI Singapore and Professor at the Department of Biochemistry at the NUS School of Medicine, found that a new type of immune T helper cells called TH-GM cells are involved in causing neuronal inflammation. The researchers found that a member of the STAT family of proteins, called STAT5, programs these newly discovered TH-GM cells and initiates an immune response triggered by interleukin IL-7, causing neuro-inflammation and damage in the central nervous system. By blocking the activity of IL-7 or STAT5, the neuro-inflammation could be prevented. The study opens up new treatment options for MS that can be used as stand-alone therapies or used along with other available treatments. The findings also provide an insight into the mechanism of the disease. The signaling pathway of the STAT proteins, the JAK-STAT signaling pathway, is involved in the regulation of the immune system, and disturbances in … Continue reading

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Senator touts bill that would help addicts

Posted: Published on December 2nd, 2014

Published: Tuesday, 12/2/2014 - Updated: 1 minute ago BY TOM TROY BLADE POLITICS WRITER After five years of successfully battling her heroin addiction, Toledo resident Tiffany Brackett joined U.S. Sen. Sherrod Brown Monday in support of a bill in Congress to get more help for people like her. Ms. Brackett, 27, said she supported Senator Browns bill to broaden access to medical treatment of opiate addiction as Ohio grapples with an epidemic of the problem, and even thought it didnt go far enough. The bill, still awaiting action in the Senate, would increase the number of patients who would be able to get methadone medication to help them break their drug habits. Senator Brown is co-sponsoring the Recovery Enhancement for Addiction Treatment Act, and said hes looking for bipartisan support in the Senate and the House. We expect bipartisan support. Theres no reason this would not pass next year, he said. Ms. Brackett told guests and the media at a news conference in the Zepf Center near downtown that medication was an important part of her kicking heroin. She said she started abusing pain bills as a teenager and progressed to shooting heroin. Shes been sober since 2009. I lost … Continue reading

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