A review of the scientific literature on Parkinson's disease, conducted by SISSA research scientists, shows that even the non-motor symptoms associated with the disease can contribute to the changes in body weight seen in patients (including those subjected to deep brain stimulation). Among the factors affecting eating habits and body weight there could be, for example, an impaired ability to derive pleasure from food and changes in motivation. These are important findings which can help to understand how to reduce these effects of Parkinson's that exacerbate an already negative clinical situation. Patients affected by Parkinson's disease often show marked changes in body weight: they may gain or lose a lot of weight depending on the stage of the disease, or they may put on up to ten kilos after deep brain stimulation (a treatment to alleviate the symptoms). This situation considerably worsens the quality of life of a person who is already suffering from heavily disabling motor disorders, so it is important to understand what are the factors that cause it. "The body weight and eating habits of Parkinson's patients change as the disease progresses," explains Marilena Aiello, SISSA researcher and first author of the study published in the journal … Continue reading
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