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Peanut in household dust linked to peanut allergy in children with eczema during infancy

Posted: Published on November 19th, 2014

PUBLIC RELEASE DATE: 18-Nov-2014 Contact: Jenny Gimpel jenny.gimpel@kcl.ac.uk 44-207-848-4334 King's College London @kingscollegelon A new study led by researchers at King's College London in collaboration with the US Consortium of Food Allergy Research and the University of Dundee has found a strong link between environmental exposure to peanut protein during infancy (measured in household dust) and an allergic response to peanuts in children who have eczema early in life. Around two per cent of school children in the UK and the US are allergic to peanuts. Severe eczema in early infancy has been linked to food allergies, particularly peanut allergy. The study, published in the Journal of Allergy and Clinical Immunology, looked at the amount of peanut protein infants aged 3-15 months were exposed to in house dust, by vacuuming dust from the living room and measuring peanut in the dust. The study was conducted in 359 children who had a high risk of developing peanut allergy because they were allergic to cow's milk or egg or had moderate to severe eczema and had tested positive for an allergy to cow's milk or egg. The study found that exposure to peanut in dust early in life doubled the risk of … Continue reading

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Peanut in household dust linked to peanut allergies, especially for children with eczema

Posted: Published on November 19th, 2014

PUBLIC RELEASE DATE: 18-Nov-2014 Contact: Johanna Younghans johanna.younghans@mountsinai.org 212-241-5093 The Mount Sinai Hospital / Mount Sinai School of Medicine @mountsinainyc Exposure to peanut proteins in household dust may be a trigger of peanut allergy, according to a study published today in the Journal of Allergy and Clinical Immunology. The study was conducted in 359 children aged 3-15 months taking part in the NIH-sponsored Consortium for Food Allergy Research (CoFAR) study. These children were at high risk of developing a peanut allergy based on having likely milk or egg allergy or eczema. The study found that the risk of having strong positive allergy tests to peanut increased with increasingly higher amounts of peanut found in living room dust. "The relationship was especially strong among children with more severe atopic dermatitis (eczema), suggesting that exposure to peanut in the environment through an impaired skin barrier could be a risk," said Hugh Sampson, MD, Professor of Pediatrics, Dean for Translational Biomedical Sciences at the Icahn School of Medicine, Director of the Jaffe Food Allergy Institute at The Mount Sinai Hospital, and the Principal Investigator for the CoFAR. Scott H. Sicherer, MD, a lead investigator for the study and the Elliot and Roslyn Jaffe … Continue reading

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Let’s CRUSH Ulcerative Colitis LIke a Coke Can – Video

Posted: Published on November 19th, 2014

Let's CRUSH Ulcerative Colitis LIke a Coke Can Justin Mirigliani crushing a Coke can on his forehead, just like he wants to do to Ulcerative Colitis! Come see Justin and his Checkmates Teammates take on t... By: Justin Mirigliani … Continue reading

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Sarepta Kickstarts Eteplirsen Study In Muscular Dystrophy

Posted: Published on November 19th, 2014

By Estel Grace Masangkay Sarepta Therapeutics announced that it has begun the clinical study of its lead exon-skipping therapeutic candidate eteplirsen for the treatment of Duchenne muscular dystrophy (DMD). Eteplirsen is an investigational drug that leverages Sareptas novel phosphorodiamidate morpholino oligomer (PMO)-based chemistry and proprietary exon-skipping technology, specifically to skip exon 51 of the dystrophin gene. The drugs mechanism of action aids in the repair of certain gene mutations that affect an estimated 13 percent of the total DMD population. Eteplirsen aims to stabilize or slow the disease process and improve the quality of life of DMD patients. The open-label study 4658-204 (Study 204) will investigate the safety of eteplirsen in patients or those who have late-stage DMD and fail a minimum 6-minute walk test score at baseline. The company said it will enroll around 20 patients treated with eteplirsen who have genotypes likely to be responsive to exon 51 skipping and who otherwise qualify for the study. Edward Kaye, CMO of Sarepta, said, The initiation of this eteplirsen study represents an important milestone for patients, their families, and the DMD community. Expanding the DMD population to include patients who are older and non-ambulant will provide additional data to support … Continue reading

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Autism: Parents warned of unscientific treatments

Posted: Published on November 19th, 2014

Professor Samuel Odom said it was often hard for parents of children with autism to access information on treatments. An international expert on the treatment of autism has warned Irish parents against interventions which are marketed as cutting edge technologies but have no basis in fact. Professor Samuel Odom, who is the keynote speaker at a major conference in Dublin today on special needs education, said it was often hard for parents of children with autism to access information on treatments or even to understand the information. I would advise them to ask: Where the evidence is that the treatment works? Can you show me where this has been tried in a very systematic way with students of autism that they actually get better? A number of alternative treatments in the US have emerged in recent years in educational settings, including dietary interventions, aquatic therapy, medical marijuana and stem cell therapy. These are sometimes promoted in opposition to applied behavioural analysis (ABA), which has been shown to be very effective, said Prof Odom. There has been a long-running battle by some parents of children with autism to have schools provide ABA as the sole method of treatment rather than a … Continue reading

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Parents of children with autism warned against unscientific treatments

Posted: Published on November 19th, 2014

Professor Samuel Odom said it was often hard for parents of children with autism to access information on treatments. An international expert on the treatment of autism has warned Irish parents against interventions which are marketed as cutting edge technologies but have no basis in fact. Professor Samuel Odom, who is the keynote speaker at a major conference in Dublin today on special needs education, said it was often hard for parents of children with autism to access information on treatments or even to understand the information. I would advise them to ask: Where the evidence is that the treatment works? Can you show me where this has been tried in a very systematic way with students of autism that they actually get better? A number of alternative treatments in the US have emerged in recent years in educational settings, including dietary interventions, aquatic therapy, medical marijuana and stem cell therapy. These are sometimes promoted in opposition to applied behavioural analysis (ABA), which has been shown to be very effective, said Prof Odom. There has been a long-running battle by some parents of children with autism to have schools provide ABA as the sole method of treatment rather than a … Continue reading

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Utah Autism Waiver Program accepting applications

Posted: Published on November 19th, 2014

SALT LAKE CITY Autism spectrum disorders affect many families here in Utah. Finding specialized treatment can be tough and expensive. The Utah Health Department says the Utah Medicaid Autism Waiver Program is in high demand. Each year about 290 kids are accepted, and right now there are 25 open spots. There are so many children in the state who have autism and are seeking out services, and this program is able to provide that to a number of kids in this state that might not otherwise have resources to receive these types of services, said Kolbi Young with the Utah Department of Health. Those spots are expected to be taken quickly, but what's different about this program is it's not like traditional Medicaid where the guidelines are very strict in terms of family income and assets. "For this program parents don't have to meet financial eligibility guideline, so it's based upon the child's income and assets. There are many, many families who qualify who would not otherwise qualify for traditional Medicaid benefits, said Young. To qualify, a child must be between the ages of 2 and 6 who have been diagnosed with an autism spectrum disorder and cant have more … Continue reading

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How Early Intervention Is Changing The Game for Autism

Posted: Published on November 19th, 2014

HENRICO, Va. (WRIC) - Today, one out of every 68 kids is diagnosed with Autism Spectrum Disorder. That rate that has more than doubled over the last decade. And children are getting the news earlier than ever, thanks to improvements in screening. Jakeman Nowak's mom says she noticed her son acting differently early in life. "Our son's name is Jakeman. He just turned three. We first noticed he had some issues when he was very young." Jakeman wasn't much older than his little brother Xavier is now when their mom noticed something was off. "He was saying, like, dada, mama, yaya, nana, and all that completely disappeared. That was the red flag that there was something really different about him that we needed to take a look at." The Nowaks quickly learned their little boy is part of a growing number of kids getting the same news. Jakeman was diagnosed with autism. "Autism used to be considered a low-incidence diagnosis. It was about 1 in every 30,000 kids back then. Over the last 30 years though, we've seen that go from one in 10,000 to one in 5,000 to now about 1 in 68," said Adam Dreyfus, director of early … Continue reading

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Double award joy for doctors

Posted: Published on November 19th, 2014

A team of stroke experts from Merseyside has won two awards in just one week. The stroke team from Aintree University Hospital was presented with an award from the Stroke Association in recognition of their professional excellence before going on to triumph at the hospitals own awards ceremony. The Highly Commended Life After Stroke Award was presented by rugby stars Danny Cipriani and Mark Cueto, who play for Sale Sharks, at the Stroke Associations Life After Stroke Awards ceremony. Within days the group was named Outstanding Team at the hospitals Proud of Aintree Excellence Awards, which were presented by acclaimed Liverpool actress and comedienne, Pauline Daniels. The award recognised the work done by the team to enhance the experience of patients at Aintree, which has one of the biggest stroke units in the region. Dr Claire Cullen, consultant physician at Aintree University Hospital, said: We are all incredibly proud to have our work recognised. We are committed to providing the best possible care for our patients during their treatment and recovery and the Stroke Association plays an important role in this. To receive two awards in the same week is an honour and testament to the hard work of the … Continue reading

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Ramsey County cuts support for sex offender day-treatment center

Posted: Published on November 19th, 2014

Dane Jorento has the kind of job many people most likely would pay to avoid. For nine years, he has been the director of ABC Mental Health Therapy, an East Side St. Paul day-treatment center that works with sex offenders who suffer from traumatic brain injury, developmental delays, autism or various forms of mental illness. The nonprofit clinic is one of three agencies in the metro that offer group therapy to low-IQ sex offenders ranging from peeping Toms to convicted rapists. Of the three agencies, only ABC mainly treats low-income clients. And within weeks, the only clinic of its kind in Minnesota might close. Ramsey County decided last year to discontinue its two day-treatment therapy contracts by Dec. 31, although the county has offered ABC an extension through March 31. "The day treatment services ABC provides are no longer in alignment with the state and county direction toward individualized treatment plans and contemporary evidence-based practices," John Siqveland, a spokesman for Ramsey County, said Tuesday. Jorento, who has led ABC since its creation, disagrees that his facility's services have fallen out of favor with the state's best practices. In fact, the Minnesota Department of Human Services recently chose ABC Mental Health … Continue reading

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