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Waikato chosen to be FAST learners for stroke

Posted: Published on November 18th, 2014

16 October 2014 Waikato chosen to be FAST learners for stroke Waikato residents will be the first in New Zealand to benefit from a large-scale public education campaign on how to recognise the symptoms of stroke. Television and radio advertising of the F.A.S.T. message from Sunday 19 October aims to increase the number of people who can recognise a stroke when it happens and know what to do. The Stroke Foundation of New Zealand says that lives and livelihoods could be saved if more people knew a stroke when they saw one, and the F.A.S.T. message is a proven way of remembering the main symptoms. A third of New Zealanders are unable to name a single symptom of stroke correctly, said SFNZ CEO Mark Vivian. The campaign launched on Sunday will try to change that and make sure more stroke cases get to hospital quicker where they can receive treatment which might save their life or reduce the damage that stroke does. The meaning of FAST should trip off everyones tongue as easily as slip-slop-slap and drop, cover and hold. Its just as important and could save just as many lives as those well-known phrases. Other countries around the world … Continue reading

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Breakthrough offers promise for spinal cord injury patients to breathe on their own again

Posted: Published on November 18th, 2014

PUBLIC RELEASE DATE: 18-Nov-2014 Contact: Jeannette Spalding jeannette.spalding@case.edu 216-368-3004 Case Western Reserve University @casenews Case Western Reserve researchers have developed a procedure that restores function to muscles involved in the control of breathing - even when they have been paralyzed for more than a year. The breakthrough offers hope that one day patients with severe spinal cord injuries will be able to breathe again without the assistance of a ventilator. Principal investigator Philippa M. Warren, PhD, presented the results Nov. 17 at Neuroscience 2014, the annual meeting of the Society for Neuroscience. The research represents a critical step forward in efforts to reverse even long-term paralysis of muscles within the diaphragm that are activated by nerve fibers that extend from the upper part of the brain stem. When those fibers are damaged in the spinal cord, electrical signals from the brain cannot reach motor nerves that leave the spinal cord to activate muscles that control vital functions. This new research offers a two-step approach to repair the part of the damage that blocks those signals. "We show that respiratory paralysis can be reversed at long intervals after spinal cord injury," said Warren, a neurosciences researcher at MetroHealth Medical Center, which … Continue reading

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Laboratory Breakthrough Offers Promise for Spinal Cord Injury Patients to Breathe on Their Own Again

Posted: Published on November 18th, 2014

Contact Information Available for logged-in reporters only Newswise Case Western Reserve researchers have developed a procedure that restores function to muscles involved in the control of breathing even when they have been paralyzed for more than a year. The breakthrough offers hope that one day patients with severe spinal cord injuries will be able to breathe again without the assistance of a ventilator. Principal investigator Philippa M. Warren, PhD, presented the results Nov. 17 at Neuroscience 2014, the annual meeting of the Society for Neuroscience. The research represents a critical step forward in efforts to reverse even long-term paralysis of muscles within the diaphragm that are activated by nerve fibers that extend from the upper part of the brain stem. When those fibers are damaged in the spinal cord, electrical signals from the brain cannot reach motor nerves that leave the spinal cord to activate muscles that control vital functions. This new research offers a two-step approach to repair the part of the damage that blocks those signals. We show that respiratory paralysis can be reversed at long intervals after spinal cord injury, said Warren, a neurosciences researcher at MetroHealth Medical Center, which is affiliated with Case Western Reserve University … Continue reading

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New high-tech cerebral palsy treatment centre opens in Canberra

Posted: Published on November 18th, 2014

Indigo receives regular treatment and speech therapy to help her develop after being diagnosed with cerebral palsy. A new purpose-built site to help ACT children diagnosed with cerebral palsy has been praised by families. The Cerebral Palsy Alliance Canberra has been operating out of rented premises in Spence since 2004 helping an estimated 400 families in the region. The opening of a $2 million therapy centre at Scullin brings together all the available support services in a state-of-the-art centre. Twenty-month-old Indigo has been receiving regular therapy to help with her development since being diagnosed with cerebral palsy as a baby. Her mother Juliette Brassington said the new centre was very welcome for families needing early intervention. "Being purpose-built I guess it's going to have the access to things like splints which we couldn't actually get without a delay at the old centre," she said. "So they have actually got the facilities to do that, and having a gym downstairs will be fantastic, and the purpose-built rooms will make a big difference." The centre was built solely through corporate and private philanthropy, and is staffed by six specialists providing a range of therapy services. Cerebral Palsy Alliance president Marelle Thornton said … Continue reading

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"Making it Possible" for Autumn Hampton

Posted: Published on November 18th, 2014

Dallas, Texas (PRWEB) November 18, 2014 The Carrick Brain Centers (http://carrickbraincenters.com), a cutting-edge rehabilitation facility that provides highly effective treatments for those suffering from severe brain injuries, announced a partnership with the Move2Improve Foundation (http://m2i.org). Together the organizations aim to raise $250,000 in crowd source funding for 21 year old Autumn Hampton, a young woman who suffered a Traumatic Brain Injury (TBI) in 2010. The money raised in this effort will allow Autumn to receive the treatment that she needs to improve her quality of life. Three weeks before her 18th birthday, Autumn Hampton suffered a severe head injury due to a fluke horse riding accident. After three years of marginal rehabilitation services, the Hamptons insurance coverage was cancelled, leaving Autumn unable to walk or speak clearly with no options for therapy. Thanks to the support of Move2Improve, Autumn underwent three weeks of intense rehabilitation at the Carrick Brain Center in Dallas, Texas during September of this year. Autumn is now walking short distances and is able to see clearly with both eyes for the first time in four years. We are very pleased with Autumns progress and excited to partner with M2I in order to make her recovery a … Continue reading

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New Federal BRAIN Research Discoveries Are Targeted to Improve Clinical Practice

Posted: Published on November 18th, 2014

On April 2, 2013, President Obama announced a new public-private partnership to develop new tools and technologies that will enable the research community to obtain a dynamic picture of the brain in action. Initially, 3 federal agenciesthe Defense Advanced Research Projects Agency (DARPA, $50M), the NIH ($40M), and the National Science Foundation (NSF, $20M)were charged with initiating new plans for the Brain Research through Advanc-ing Innovative Neurotechnologies (BRAIN) Initiative activities. That list recently grew to include the FDA and the Intelligence Advanced Research Projects Agency (IARPA).1 Those activities complement work supported by the initial private sector partners, the Allen Institute for Brain Science ($60M), the Howard Hughes Medical Institute ($30M), the Salk Institute for Biological Studies ($28M), and the Kavli Foundation ($4M). In most cases, the funding amounts indicate investments made in 2014. In addition to these investments in the American BRAIN Initiative, there is a significant investment by the European Commission in a related effortthe Human Brain Project.2 That project is focused on developing new modeling and computing technologies to understand the brain. The Japanese have recently announced an initiative that will fund research on the marmoset as well as on tool and technology development.3,4 Other countries seem to … Continue reading

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Toxic Tau Of Alzheimer's May Offer A Path To Treatment

Posted: Published on November 18th, 2014

A tangle of protein (green) in this scanning electron micrograph of a brain cell of an Alzheimer's patient lies within the cytoplasm (blue) of the cell. The tangle consists of clumps of a toxic form of tau. Thomas J. Deerinck/Corbis hide caption A tangle of protein (green) in this scanning electron micrograph of a brain cell of an Alzheimer's patient lies within the cytoplasm (blue) of the cell. The tangle consists of clumps of a toxic form of tau. After years of setbacks, Alzheimer's researchers are sounding optimistic again. The reason: a brain protein called tau. At this year's Society for Neuroscience meeting in Washington, D.C., there are more than 100 papers on tau, which is responsible for the tangles that form in the brains of people with Alzheimer's. In the past, tau has received less attention than another protein called amyloid beta, which causes the sticky plaques associated with Alzheimer's. "Many people focused on amyloid beta for many years," says Julia Gerson, a graduate student in neuroscience at the University of Texas Medical Branch, who presented a paper on tau at the neuroscience meeting. "Now it's coming out that tau might be more important." If we could figure out … Continue reading

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CereScan Extending Reach with Medical Imaging Center in Louisiana

Posted: Published on November 18th, 2014

Denver, CO (PRWEB) November 18, 2014 CereScan Corp. is proud to announce a groundbreaking neuroimaging partnership agreement with Diagnostic Imaging Services (DIS) in Metairie, Louisiana. This collaborative effort will expand CereScans sophisticated brain diagnostic products and DISs state of the art neuroimaging capabilities to adults and children who are suffering from invisible brain issues. This partnership creates a powerful combination of cutting edge technologies focused on identifying specific brain related problems in areas such as traumatic brain injury, Alzheimers disease, and attention deficit disorder. The State of Louisiana and the southeast region of the country now have easy access to the capabilities that these two companies can deliver to medical professionals who are focused on finding solutions for patients with chronic brain disorders. CereScan is the nations leader in providing statistically measured brain diagnostics based on a new generation of imaging software and SPECT (Single Photon Emission Computed Tomography) neuroimaging technologies. Since 2009, patients from all over the country and throughout the world have consulted Denver-based CereScan and its leading physicians concerning chronic neurological and psychiatric issues. By partnering with DIS and their extensive experience in nuclear imaging, this Metairie-center will now offer unmatched functional brain imaging capabilities in the … Continue reading

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Sanofi's Lemtrada Gets U.S. Approval, Carries Boxed Warning – Analyst Blog

Posted: Published on November 18th, 2014

Sanofi 's ( SNY ) Lemtrada has finally gained FDA approval for the treatment of patients suffering from relapsing forms of multiple sclerosis (MS). The drug's U.S. indication is however restricted to patients who have responded inadequately to two or more MS drugs. Lemtrada's label in the U.S. comes with a boxed warning stating that there is a risk of serious, sometimes fatal autoimmune conditions as well as serious and life-threatening infusion reactions. The drug may also cause an increased risk of malignancies including thyroid cancer, melanoma and lymphoproliferative disorders. Moreover, the drug will be available under a Risk Evaluation and Mitigation Strategy. Lemtrada's road to approval has not been smooth. Towards the end of last year, the FDA had issued a complete response letter for Lemtrada. Lemtrada is already approved in over 40 countries around the globe including the EU, Canada and Australia. The drug is also under review in several other countries. Sanofi has an agreement with Bayer ( BAYRY ) to co-promote Lemtrada in the U.S. However, Sanofi holds worldwide rights to the development and commercialization of Lemtrada for MS. Our Take The FDA approval of Lemtrada is a positive development for Sanofi, which needs to bring … Continue reading

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Establishment of induced pluripotent stem cells from Werner syndrome fibroblasts

Posted: Published on November 18th, 2014

2 hours ago Associate Professor Akira Shimamoto and Professor Hidetoshi Tahara at the Graduate School of Biomedical & Health Science in Hiroshima University, Professor Koutaro Yokote at the Graduate School of Medicine in Chiba University, Visiting Professor Makoto Goto at the Medical Center East in Tokyo Women's Medical University, and collaborators including the staff at the Cancer Chemotherapy Center in the Japanese Foundation for Cancer Research, Tottori University, and Keio University established induced pluripotent stem (iPS) cells from the fibroblasts of Werner Syndrome patients. These results were published in PLOS ONE in an article entitled "Reprogramming Suppresses Premature Senescence Phenotypes of Werner Syndrome Cells and Maintains Chromosomal Stability over Long-Term Culture." Werner syndrome is characterized by the premature appearance of features associated with normal aging and cancer predisposition. This syndrome occurs frequently in Japan, affecting 1 in 20,000 to 1 in 40,000 people. The therapeutic methods for this disease are very limited and it is expected that iPS cells can be used for the development of innovative therapies. Dr. Shimamoto and his collaborators analyzed patient-derived iPS cells and found that telomeric abnormalities in the fibroblasts of these patients, which were caused by the lack of WRN helicase encoded by the … Continue reading

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