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Autisms Gut-Brain Connection

Posted: Published on November 14th, 2014

Stress can send your stomach into a painful tailspin, causing cramps, spasms and grumbling. But trouble in the gut can also affect the brain. This two-way relationship may be an unlikely key to solving one of medicine's most pressingand perplexingmysteries: autism. Nearly 60 years after the disorder was first identified, the number of cases has surged, and the United Nations estimates that up to 70 million people worldwide fall on the autism spectrum. Yet there is no known cause or cure. But scientists have found promising clues in the gut. Research has revealed striking differences in the trillions of bacteria - collectively known as the microbiomein the intestines of autistic and healthy children. But the gut bacteria in autistic individuals aren't just different. Researchers at the California Institute of Technology have shown for the first time that they may actually contribute to the disorder. Last month, they reported in the journal Cell that an experimental probiotic therapy alleviated autism-like behaviors in mice and are already planning a clinical trial. Today autism is treated primarily through behavioral therapy. But the new study suggests that treatment may one day come in the form of a probioticlive, "friendly" bacteria like those found in … Continue reading

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Lifeline action quickens after stroke's slam

Posted: Published on November 14th, 2014

Hilary Wong Friday, November 14, 2014 A special ward for stroke patients at Queen Elizabeth Hospital has cut by 13 minutes the time to administer life-saving injections. That advance follows a 24-hour intravenous thrombolytic service set up in 2009 for stroke patients at the hospital. A support team was established two years later. Neurology consultant Fong Wing-chi said that before acute stroke ward H6 was set up the time between a patient being admitted to an emergency room and receiving the injection was 74 minutes. Now it is 61 minutes. "Nearly 40 percent of stroke patients can receive treatment within 60 minutes of arriving at the accident and emergency department," Fong added. And from December last year to last month, over 73 percent of stroke patients received treatment in the stroke ward. Benefits were being seen in the proportion of patients being discharged directly from the hospital after treatment, rising to 52.8 percent in December 2012 to November 2013 compared to 41 percent from December 2010 to November 2011. Also on the special ward, nurses are ready to provide thrombolysis service at any time, Fong said. View post: Lifeline action quickens after stroke's slam … Continue reading

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Guidelines Agree: Most Patients with Chronic Kidney Disease Should Take Statins

Posted: Published on November 14th, 2014

Contact Information Available for logged-in reporters only Newswise BIRMINGHAM, Ala. A gradual loss of kidney function over time or chronic kidney disease (CKD) increases the risk of heart disease and stroke. Two sets of cholesterol-treatment guidelines published in 2013 inform the decision to use statins. One set is specifically for patients with CKD, while the other is for the general population. University of Alabama at Birmingham experts compared them to find similarities and differences and to also determine if CKD patients are taking statins unnecessarily. Around 26 million adults in the United States have CKD, according to the National Kidney Foundation, and heart disease and stroke are major causes of death among them. In Contrasting Cholesterol Management Guidelines for Adults with CKD, published in the Journal of the American Society of Nephrology, UAB School of Public Health investigators compared the American College of Cardiology/American Heart Association cholesterol treatment guideline and the Kidney Disease Improving Global Outcomes Foundation Clinical Practice Guideline for Lipid Management in CKD. Study lead author Lisandro Colantonio, M.D., doctoral candidate in the UAB Department of Epidemiology, said the two guidelines target different populations in treatment recommendations. The ACC/AHA guideline is aimed toward statin treatment decisions for the … Continue reading

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Drug developer NeuroDerm to begin Nasdaq IPO

Posted: Published on November 14th, 2014

Rehovot-based NeuroDerm, which has developed a transdermal drug delivery system for the treatment of Parkinson's disease, is expected to price its Nasdaq IPO this evening. The company is seeking to raise $58-72 million at a company value of $290 million. Jefferies and Cowen & Company are the joint bookrunners on the deal with Oppenheimer and Roth Capital acting as secondary underwriters. The company will trade under the NDRM ticker. NeuroDerm's main shareholders include Omrix Biopharmaceuticals founder Robert Taub (28%) who serves as Chairman, Uwe Wascher (25.9%) a former GE senior executive and close friend of Taub and private investor Prof. Shmuel Cabilly (22.2%), while Capital Point Ltd. (TASE:CPTP) holds 16.6%. NeuroDerm's product for treating Parkinson's disease is set for a Phase III trial in 2015. A product to treat more severe forms of Parkinson's is currently in a Phase IIa trial and if successfully completed will proceed to a Phase IIb trial in 2015. A company with a rival product, Civitas, was recently sold for $525 million. Published by Globes [online], Israel business news - http://www.globes-online.com - on November 13, 2014 Read the rest here: Drug developer NeuroDerm to begin Nasdaq IPO … Continue reading

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Cerebral Palsy Treatment Consent Video – Video

Posted: Published on November 14th, 2014

Cerebral Palsy Treatment Consent Video Cerebral Palsy Treatment Consent Video. By: Meghan Melo … Continue reading

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Vacant Chester Township care center a sign of the times

Posted: Published on November 14th, 2014

CHESTER TWP. - The 15-acre Glenlora property, a former nursing home on West Main Street remains empty and unused, eight years after the township bought the property for $3 million. The plan at the time of purchase of the 63 W. Main St. property was to lease it to United Cerebral Palsy, which planned to develop a rehabilitation and respite facility along with 10 apartments for low-income people with disabilities. The housing would have met the township's affordable housing requirement under the state's Council on Affordable Housing (COAH). But United Cerebral Palsy was unable to secure needed funding and the plans fell through. The township bought the facility with funds paid by developers to the town's affordable housing trust fund. "The idea was that individuals who were caregivers could arrange to have their ward stay at the center for a period of time so that the caregivers could do something, like take a vacation, while the person they cared for would be in a position to go somewhere seeking treatment and accommodation," said Mayor Bill Cogger. "It's not an easy condition to travel with. They would have done rehabilitative work there as well with patients. Unfortunately, after we purchased it, … Continue reading

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Quarter of Bulgarian MPs to Donate Their First Salaries

Posted: Published on November 14th, 2014

As many as 62 out of Bulgaria's 240 lawmakers have promised to donate their October salaries for a cause at the end of a campaign to save a child's life. Betina Terzieva, a young girl, wrote earlier an open letter to MPs calling on them to give their first money as lawmakers to help Slavi Edrev, a child that has cerebral palsy and epilepsy and needs treatment. Terzieva started a campaign titled Make an MP Save a Child's Life on Facebook which ended Thursday, November 13. Some EUR 105 000 are needed for the boy's treatment. If all 62 lawmakers who promised to donate their salaries hold on to their promise, they might be able to collect the money as each MP received BGN 2590 in October. Parliament held virtually two sessions in October, but some lawmakers are adamant they cannot renounce the entire amount of money they earned within their period, claiming they need it to make ends meet. Read more: Quarter of Bulgarian MPs to Donate Their First Salaries … Continue reading

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New therapy aims to help treat veterans with brain injuries

Posted: Published on November 14th, 2014

The U.S. military is taking a hard look at how to treat veterans with severe brain injuries, and some of the most groundbreaking research is happening in Dallas. The number of Americans with traumatic brain injuries went up dramatically during the wars in Iraq and Afghanistan. It peaked in 2011 and has been declining slowly since. But last year alone, there were still more than 27,000 new cases. Many of the worst brain injuries are combat-related, like the case of one former Navy SEAL who shared his story with FOX 4. It's hard to say what's more incredible the survival of retired SEAL Sr. Chief Mike Day, or the unorthodox therapy that might just become the future solution to the treatment for people suffering from PTSD and traumatic brain injury. Day suffers from what's called the invisible wounds of war, but his body is riddled with very visible scars from a 2007 battle with al-Qaida operatives. "I got into a gunfight with these four guys, said Day. I was shot 27 times. I got shot in both legs, both arms, my abdomen, my buttocks, my scrotum, my left thumb, and my right scapula was shattered in about 30 pieces. A … Continue reading

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TBI Reauthorization Act Passes in House with Bi-partisan Support

Posted: Published on November 14th, 2014

Vienna, VA (PRWEB) November 14, 2014 The Brain Injury Association of America (BIAA) is pleased to announce that the House of Representatives passed the Traumatic Brain Injury (TBI) Reauthorization Act of 2014 and the bill is on its way to President Obama for his signature. The TBI Act reauthorizes existing TBI programs within the U.S. Department of Health and Human Services (HHS) and provides appropriations for those programs through FY2019. The legislation also provides new authority for the Centers for Disease Control and Prevention (CDC) to review brain injury management in children, identify ongoing and potential opportunities for research, and instructs the CDC to report back to Congress on their findings. This is the day we have worked toward for several years, said Susan Connors, President and CEO of BIAA. The passage of this reauthorization of the TBI Act means that research relating to children with brain injuries will gain more attention. TBI prevention and surveillance programs at CDC will continue, as will the state grant program and the protection and advocacy grant program currently administered by the Health Resources and Services Administration (HRSA), she added. I would especially like to recognize all of our grassroots advocates, without whom this … Continue reading

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Do spinal cord injuries cause subsequent brain damage?

Posted: Published on November 14th, 2014

PUBLIC RELEASE DATE: 14-Nov-2014 Contact: University of Maryland School of Medicine Public Affairs dkohn@som.umaryland.edu 410-706-7590 University of Maryland School of Medicine @ummedschool Baltimore, Md., November 14, 2014--Most research on spinal cord injuries has focused on effects due to spinal cord damage and scientists have neglected the effects on brain function. University of Maryland School of Medicine (UM SOM) researchers have found for the first time that spinal cord injuries (SCI) can cause widespread and sustained brain inflammation that leads to progressive loss of nerve cells, with associated cognitive problems and depression. The research, published recently in two articles, one in of the Journal of Neuroscience, the other in Cell Cycle, highlights the close links between spinal cord injury and loss of brain function, and suggests potential treatment to prevent such changes. "Animal studies have shown that traumatic brain injury, even mild repeated injuries, can result in progressive brain tissue damage and cognitive decline, as well as widespread brain inflammation. But little research has examined whether these problems occur after spinal cord injuries," said UM SOM anesthesiology professor and noted neurobiologist Alan Faden, MD, who led the study. "Our studies the first to show that isolated SCI can cause progressive loss … Continue reading

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