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DNA: Don't vote for BJP, it will impose a Hindu CM, warns PDP leader Peer Mansoor Another controversial statement by a PDP leader has sparked communal tension in the valley. A legislator of the People's Democratic Party (PDP) Peer Mansoor asked the people not to vote for... By: Zee News … Continue reading →

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Contact Information Available for logged-in reporters only Newswise Damage to DNA is an issue for all cells, particularly in cancer, where the mechanisms that repair damage typically fail. The same agents that damage DNA also damage its sister molecule messenger RNA (mRNA), which ferries transcripts of the genes to the tens of thousands of ribosomes in each cell. But little attention has been paid to this damage. Everybody thought, Why care about the messenger RNA? These molecules have high turnover rates and are quickly degraded, so what does it matter if one is damaged? said Hani Zaher, PhD, assistant professor of biology in Arts & Sciences at Washington University in St. Louis. In organisms like E. coli or yeast, thats probably true, Zaher said. You dont have to worry about mRNA because it turns over really fast. But in neurons you cant use that argument because an mRNA can persist, in some cases for days. And if that mRNA is really damaged it can become a big problem. There may be cases where messenger RNA is just as important as DNA, said Carrie Simms, PhD, a postdoctoral associate in Zahers lab. Clearly oxidative damage to RNA is somehow involved in … Continue reading →