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Riordan-McKenna Institute Founders, Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna Present at the Mid …

Posted: Published on October 31st, 2014

Chicago, Illinois (PRWEB) October 30, 2014 On October 26th at the Mid American Regenerative and Cellular Medicine Showcase in Chicago, leading applied stem cell research scientist Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna presented talks on New Techniques for Enhancing Stem Cell Therapy Effectiveness and Orthopedic Surgical Applications For Stem Cells. Dr. Riordan focused on historical medical uses of amniotic membrane and the properties of AlphaGEMS that include: wound healing; inflammation and pain reduction; fibrosis risk reduction; growth factor source; adhesion reduction; regeneration support and stem cell enhancement, specifically regarding the mesenchymal stem cells contained within BMAC. Dr. McKenna discussed the latest applications of BMAC stem cells in orthopedic surgeries like anterior cruciate ligament (ACL) reconstruction and how BMAC injections can virtually eliminate infection risk, reduce complications, increase graft strength, reduce post-surgical inflammation and significantly reduce recovery time. Dr. McKenna also talked about how bone marrow can now be safely and relatively painlessly harvested using his patented BioMAC catheter under local, not general anesthesia. Dr. Riordan and Dr. McKenna are co-founders of the Riordan-McKenna Institute (RMI), which will be opening soon in Southlake, Texas. RMI will specialize in regenerative orthopedics including non-surgical stem cell therapy and stem cell-enhanced … Continue reading

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Accident prone eczema patients

Posted: Published on October 30th, 2014

PUBLIC RELEASE DATE: 29-Oct-2014 Contact: Erin White ewhite@northwestern.edu 847-491-4888 Northwestern University @northwesternu CHICAGO --- Intense itching and dry, irritable skin aren't the only problems adults with eczema face. They are at greater risk of accidental bone fractures and other injuries, a new Northwestern Medicine study has found. This is the first study to find adult eczema is a risk factor for fractures and other injuries. The increased odds of accidental injury could be directly related to the side effects of steroids and sedating antihistamines commonly prescribed to treat the skin disorder or the under-treatment of severe cases, study authors suggest. "Many eczema patients who are prescribed medication for itch are often given sedating antihistamines or steroids, but those medications may come at a price," said Jonathan I. Silverberg, M.D., senior author of the study. "Sedatives cause fatigue, and steroids can lead to bone density problems and osteoporosis." Silverberg is an assistant professor of dermatology at Northwestern University Feinberg School of Medicine and an attending physician at Northwestern Memorial Hospital. The study, published Oct. 29 in the journal JAMA Dermatology, validates what Silverberg sees regularly at the Northwestern Multidisciplinary Eczema Center. "Last month three of my patients with eczema cancelled at … Continue reading

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Eczema Tied to Bone Fracture Risk in Study

Posted: Published on October 30th, 2014

Risk was small; distractions caused by itch and sleep problems are possible factors, experts say WebMD News from HealthDay By Steven Reinberg HealthDay Reporter THURSDAY, Oct. 30, 2014 (HealthDay News) -- The skin condition eczema may increase slightly the risk of broken bones and injured joints, a new study reports. In a study of 34,500 adults, researchers found that among 7 percent of people who had an eczema flare-up in the past year, 1.5 percent had a bone or joint injury and 0.6 percent had an injury that caused a limitation of function. Compared to people without eczema, those with the skin condition had more than double the risk of having had a fracture or bone or joint injury, according to the study. "Adults with eczema have higher rates of injuries, including fractures and bone and joint injuries," said lead researcher Dr. Jonathan Silverberg, an assistant professor of dermatology at Northwestern University in Chicago. Although this study found an association between eczema and bone and joint injuries, it wasn't designed to prove whether eczema is somehow a direct cause of those injuries. Another expert said follow-up research is necessary. "Further studies would be needed to show if there's a direct … Continue reading

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Moms, Regulators, Biotech Startups, and the Battle Over a Potentially Life-Saving Drug

Posted: Published on October 30th, 2014

Photograph by Ryan PflugerLeffler's son Aidan was diagnosed with Duchenne in 2006 The 2014 World Cup elevated soccer to the top of Aidan Lefflers roster of obsessions, rivaled only by endangered big catsespecially jaguars, the coolestand Star Wars spaceships. In recognition of his new interest, hes set up a miniature soccer field with 4-foot-wide goals in his backyard in suburban Bellevue, Wash. Watch this! he shouts, preparing to fire a penaltykick. Small for his age, Aidan, 11, moves awkwardly, shoulders high and hunched. He uses a lightweight plastic beach ball, not a regulation leather soccer ball. He begins his approach, pulls back his right foot, andcollapses to the grass. Mitch Leffler, the sole spectator, moves toward his son. Im OK, Aidan says. I can do it. He struggles onto his hands and knees, raises his butt, places his hands one at a time on his thighs, and slowly pushes himself into an upright position. My leg just wasnt there, he says matter-of-factly. His father nods, and the game resumes. Aidan has Duchenne, the deadliest strain of muscular dystrophy. Its inherited maternally on the X chromosome and mostly afflicts boys. Parents typically sense something is wrong when their sons at 3 … Continue reading

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Scientists link 60 genes to autism

Posted: Published on October 30th, 2014

By Danielle Ryan, Special to CNN updated 2:46 PM EDT, Thu October 30, 2014 Genetic research has been used to treat all kinds of disorders and diseases. STORY HIGHLIGHTS (CNN) -- Researchers have found dozens of new genes that may play a role in causing autism, according to two studies published Wednesday in the medical journal Nature. Scientists identified 60 genes with a greater than 90% chance of increasing a child's autism risk. Previous research has yielded only 11 genes that had been confirmed with this level of certainty. Though other studies have shown the importance of genetics in the development of autism, experts say these new studies zero in on the exact nature of the genetic mutations that cause the disorder. The researchers say these genes appear to be clustering around three sets of key biological functions. The first set focuses on the development of synapses in the brain, which are responsible for all kinds of communication between nerves. The second set is responsible for the creation of genetic instructions, and the third is responsible for DNA packaging within cells. Each of these functions could have an effect on the individual that would cause the traits commonly associated with … Continue reading

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Gene advance for spotting autism

Posted: Published on October 30th, 2014

By Danielle Ryan, Special to CNN October 30, 2014 -- Updated 1846 GMT (0246 HKT) Genetic research has been used to treat all kinds of disorders and diseases. STORY HIGHLIGHTS (CNN) -- Researchers have found dozens of new genes that may play a role in causing autism, according to two studies published Wednesday in the medical journal Nature. Scientists identified 60 genes with a greater than 90% chance of increasing a child's autism risk. Previous research has yielded only 11 genes that had been confirmed with this level of certainty. Though other studies have shown the importance of genetics in the development of autism, experts say these new studies zero in on the exact nature of the genetic mutations that cause the disorder. The researchers say these genes appear to be clustering around three sets of key biological functions. The first set focuses on the development of synapses in the brain, which are responsible for all kinds of communication between nerves. The second set is responsible for the creation of genetic instructions, and the third is responsible for DNA packaging within cells. Each of these functions could have an effect on the individual that would cause the traits commonly associated … Continue reading

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Mobile unit offers quicker stroke treatment

Posted: Published on October 30th, 2014

Published October 30, 2014 Time its one of the most crucial elements when caring for a stroke patient. During a stroke, two million brain cells die every minute, said Dr. Peter Rasmussen of the Cleveland Clinic. The brain begins to die the moment it begins to lose blood supply and its flow of oxygen, he said. Its vital to administer the clot-busting drug tissue plasminogen activator (tPA), something that has been difficult to do, until now. Medical professionals are now going to the patients, instead of making patients travel to them. "Think of the mobile stroke unit as being an emergency room on wheels. Onboard the mobile stroke unit we have a CAT scan, all the laboratory equipment we need to evaluate a patient early on with a stroke, wireless connectivity back to our hospital and, all the medications needed to treat the patient, Rasmussen said. The mobile stroke unit was named the number one innovation at the Medical Innovations Summit. One woman said it saved her grandmothers life. I noticed that her left side was just she wasnt really using her left hand or left arm. And she wasnt using her left leg, she was dragging it, said Courtney … Continue reading

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For stroke patients, hospital bed position is delicate balancing act

Posted: Published on October 30th, 2014

PUBLIC RELEASE DATE: 30-Oct-2014 Contact: Jim Ritter jritter@lumc.edu 708-216-2445 Loyola University Health System @LoyolaHealth MAYWOOD, Ill. (Date) During the first 24 hours after a stroke, attention to detail --such as hospital bed positioning -- is critical to patient outcomes. Most strokes are caused by blood clots that block blood flow to the brain. Sitting upright can harm the patient because it decreases blood flow and oxygen to the brain just when the brain needs more blood. Thus, it's reasonable to keep patients lying flat or as nearly flat as possible, according to a report in the journal MedLink Neurology by Loyola University Medical Center neurologist Murray Flaster, MD, PhD and colleagues. But strokes also can increase intracranial pressure (brain swelling) that can damage the brain. Sitting upright helps improve blood drainage and reduce intracranial pressure -- but at a cost of reduced blood flow to the brain. "There are few data to guide decision making in this difficult situation," Flaster and colleagues write. Further complicating stroke care, some patients have orthopnea (difficulty breathing while lying flat). In such patients, the head of the bed should be kept at the lowest elevation the patient can tolerate. Finally, frequent changes in body … Continue reading

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Patients going off shore for MS treatment | Australian Broadcasting Corporation (ABC) News – Video

Posted: Published on October 30th, 2014

Patients going off shore for MS treatment | Australian Broadcasting Corporation (ABC) News Sarah Tilbury's from Kingston SE, South Australia TV Clip "My Story" in News on the Australian Broadcasting Corporation (ABC) 7:30 South Australia Station po... By: DIAD0NU … Continue reading

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UCLA Gene Discovery Shows How Stem Cells Can Be Activated to Help Immune System Respond to Infection

Posted: Published on October 30th, 2014

Contact Information Available for logged-in reporters only Newswise In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez-Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection. This discovery lays the groundwork for a better understanding of the role progenitor cells can play in immune system response and could lead to the development of more effective therapies for a wide range of diseases. The two-year study was published online October 30, 2014 ahead of print in the journal Current Biology. Progenitor cells are the link between stem cells and fully differentiated cells of the blood system, tissues and organs. This maturation process, known as differentiation, is determined in part by the original environment that the progenitor cell came from, called the niche. Many of these progenitors are maintained in a quiescent state or "standby mode" and are ready to differentiate in response to immune challenges (such as stress, infection or disease). Dr. Gabriel Ferguson, a postdoctoral fellow in the lab of Dr. Martinez-Agosto and first author of … Continue reading

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