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Genetic factors behind surviving or dying from Ebola shown in mouse study

Posted: Published on October 30th, 2014

PUBLIC RELEASE DATE: 30-Oct-2014 Contact: Leila Gray leilag@uw.edu 206-685-0381 University of Washington Health Sciences/UW Medicine A newly developed mouse model suggests that genetic factors are behind the mild-to-deadly range of reactions to the Ebola virus. People exposed to Ebola vary in how the virus affects them. Some completely resist the disease, others suffer moderate to severe illness and recover, while those who are most susceptible succumb to bleeding, organ failure and shock. In earlier studies of populations of people who have contracted Ebola, these differences are not related to any specific changes in the Ebola virus itself that made it more or less dangerous; instead, the body's attempts to fight infection seems to determine disease severity. In the Oct. 30 edition of Science, scientists describe strains of laboratory mice bred to test the role of an individual's genetic makeup in the course of Ebola disease. Systems biologists and virologists Angela Rasmussen and Michael Katze from the Katze Laboratory at the University of Washington Department of Microbiology led the study in collaboration with the National Institutes of Health's Rocky Mountain Laboratories in Montana and University of North Carolina at Chapel Hill. Research on Ebola prevention and treatment has been hindered by … Continue reading

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Cellular alchemy turns skin cells into brain cells

Posted: Published on October 30th, 2014

Move over stem cells. A different kind of cellular alchemy is allowing cells to be converted directly into other tissues to treat disease or mend injuries. Stem cells have long been touted as the future of regenerative medicine as they can multiply indefinitely and be turned into many different cell types. Ideally, this would take a personal approach a patient's own cells would be converted into whatever type of cell is required to fix their injury or treat their symptoms. Earlier this year, for instance, people with age-related macular degeneration, the most common cause of blindness in the West, had retinal cells made from their own stem cells injected into their eyes. Mature cells can be converted into stem cells by exposing them to a cocktail of chemicals that reverts them back to an embryonic-like state. Another set of chemicals is then used to turn the cells into the desired tissue type. Skipping the stem cell stage would be more efficient, says Andrew Yoo of Washington University in St Louis, Missouri, and would reduce the chance that the new tissue could grow into a tumour a risk with stem cells because of their capacity to regenerate. Yoo has now managed … Continue reading

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Stem Cells Used to Grow Mini-Stomachs Seeking Treatments

Posted: Published on October 30th, 2014

Researchers are using stem cells to grow tiny three-dimensional human stomachs that are structurally similar to the real thing, helping investigators seek treatments for gastric diseases such as ulcers and cancer. Researchers carefully added growth hormones to embryonic or induced stem cells in a lab for as long as five weeks to encourage the development of gastric tissue, according to the findings published today in the journal Nature. The mini-stomachs, which even produce hormones that regulate the secretion of acid and digestive enzymes, may help discover therapies for diseases that affect as much as 10 percent of the worlds population. The researchers are experimenting with tissue from the mini-stomachs to use as grafts for treating peptic ulcers, said James Wells, a professor of pediatrics at Cincinnati Childrens Hospital Medical Center in Ohio. Eventually they may be able to make larger organs that could be used for transplant, he said. The transplant of a whole stomach is a way off, but its within a reasonable time frame to generate in a petri dish pieces of stomach to patch ulcers, Wells said in a telephone interview. There is no reason to think that if we can do this in miniature that we … Continue reading

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Business Beat: Hybrid MD, Hangar 18, Pierside Kitchen and Bar and Surf Side Taxi

Posted: Published on October 30th, 2014

Compiled by Jim Shilander Now Open Hybrid MD 1031 Avenida Pico, Suite No. 103 949.492.1919, http://www.hybridmdoc.com Dr. Colin Jairam has brought his Hybrid medical practice to San Clemente, to an area he says is underserved. Photo: Jim Shilander Dr. Colin Jairam said he created his new practice to provide a level of care in several different areas of medicine. A hybrid is a mixture of different things. The reason were called hybrid is were a mix of three different medical specialties, Jairam said. The practice includes urgent carewhich Jairam had practiced previouslyas well as aesthetic medicine and age management medicine. Aesthetic medicine involves the use of injectables, to fill in deep lines and wrinkles on the face, as well as the use of a laser, which the practice has on-site. The laser is typically used for hair removal, skin resurfacing, vein treatment and skin tightening. Continued here: Business Beat: Hybrid MD, Hangar 18, Pierside Kitchen and Bar and Surf Side Taxi … Continue reading

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The International Society of Aesthetic Plastic Surgery (ISAPS) Issues Warnings to Patients Regarding Unlicensed …

Posted: Published on October 30th, 2014

New York, NY (PRWEB) October 29, 2014 The International Society of Aesthetic Plastic Surgery (ISAPS) has issued a warning to all individuals seeking less expensive cosmetic surgical procedures, particularly outside their home country, and especially in the hands of unlicensed practitioners operating without board certification. In light of two recent deaths of UK citizens who traveled to other countries to have cosmetic procedures performed by un-certified practitioners, ISAPS is also calling for global changes in legislation to address these unnecessary and tragic deaths in an effort to insure a higher level of patient safety. Cosmetic surgery abroad can be incredibly risky because the standards vary from one country to the next. It is essential that patients find board-certified plastic surgeons, regardless of where they have a procedure performed, noted Susumu Takayanagi, MD, President of ISAPS. Patient safety is our highest priority. ISAPS membership is exclusive to board-certified plastic surgeons who must be current members of their national plastic surgery society. Over five years ago, ISAPS established a symbol of patient safety, a diamond comprised of four factors that are critical to the practice of safe aesthetic plastic surgery: Patients fall prey to unlicensed physicians because of the misconception that anyone … Continue reading

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Beyond the Dish | A developmental biologist muses about …

Posted: Published on October 30th, 2014

Researchers at Wake Forest Baptist Medical Centers Institute for Regenerative Medicine have hit upon a new strategy for tissue healing: mobilizing the bodys stem cells to the site of injury. Thus harnessing the bodys natural healing powers might make in body regeneration of muscle tissue is a possibility. Sang Jin Lee, assistant professor of Medicine at Wake Forest, and his colleagues implanted small bits of biomaterial scaffolds into the legs of rats and mice. When they embedded these scaffolds with proteins that mobilize muscle stem cells (like insulin-like growth factor-1 or IGF-1), the stem cells migrated from the muscles to the bioscaffolds and formed muscle tissue. Working to leverage the bodys own regenerative properties, we designed a muscle-specific scaffolding system that can actively participate in functional tissue regeneration, said Lee. This is a proof-of-concept study that we hope can one day be applied to human patients. If patients have large sections of muscle removed because of infections, tumors or accidents, muscle grafts from other parts of the body are typically used to restore at least some of the missing muscle. Several laboratories are trying the grow muscle in the laboratory from muscle biopsies that can be then transplanted back into … Continue reading

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Medical groups call for major stem cell investment from public, private sector

Posted: Published on October 30th, 2014

OTTAWA - A coalition of Canadian stem cell advocates, researchers and charities is calling for $1.5 billion in private and public funding for stem cell therapy over the next 10 years. The coalition's action plan is aimed at cementing Canada's reputation as a stem cell leader, one that uses stem cell science to reduce suffering and death from cardiovascular diseases, cancer, diabetes, vision loss, spinal cord injuries and other conditions. James Price, the president and CEO of the Canadian Stem Cell Foundation, says the action plan could help millions of people with new, life-changing therapies. The action plan's call for funding includes a $50 million scaled annual average commitment by the federal government. The Centre for Commercialization of Regenerative Medicine estimates the action plan could also create more than 12,000 jobs due to the growth of existing companies and the development of new enterprises aimed at global markets. Read more from the original source: Medical groups call for major stem cell investment from public, private sector … Continue reading

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Seminar on Regenerative Medicine Open to Public

Posted: Published on October 30th, 2014

JACKSON, Tenn. (PRWEB) October 30, 2014 Dr. Roy Schmidt and the staff of the Pain Specialist Center will host a free seminar and question-and-answer session about regenerative medicine on Tuesday, Nov. 11 at 6 p.m. Held at the clinic at 15 Stonebridge Blvd. in Jackson, the hour-long event will allow attendees to ask questions about stem cell therapy and platelet rich plasma therapy in a relaxed atmosphere. Guests also will have the chance to talk to individuals who have received regenerative medicine treatments, which focus on helping patients relieve pain by supporting the healing process. Stem cell therapy focuses on delivering the patients own stem cells to parts of the body that are in need. After adipose tissue (comprised of fat cells) is taken from the patients body, it is made into a stem cell concentrate. That concentrate is injected at the focal point of pain or area that needs healing. Schmidt, who is certified to administer stem cell therapy, was trained by Bioheart Chief Scientific Officer Kristin Comella. Comella has been recognized as a national leader in stem cell therapy. Platelet rich plasma (PRP) or platelet concentrates have been studied extensively since the 1990s. While similar products previously used … Continue reading

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Stem Cell Treatment for SCI Documentary Part 10 – Video

Posted: Published on October 30th, 2014

Stem Cell Treatment for SCI Documentary Part 10 via YouTube Capture. By: frnkmckenzie … Continue reading

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The Miracle of Stem Cell Therapy at Adler Footcare Regenerates Cells, Heals Foot Pain

Posted: Published on October 30th, 2014

New York, New York (PRWEB) October 29, 2014 Stem cell therapy is the future of foot pain treatment. New York podiatrists at Adler Footcare are using ethical stem cell treatments for foot problems to help speed healing, minimize pain, and reduce swelling. Stem cells are cells that havent quite yet determined their role in the body. This gives them the ability to turn into anything. The treatment is being used for problems causing foot pain, such as Achilles tendonitis, plantar fasciitis, and arthritis of the first toe joint. Stem cells help regenerate new cartilage and helps tissue heal much quicker. "Stem cells turn into everything," said Dr. Jeffrey Adler, Medical/Surgical Director & Owner of Adler Footcare. "So basically, if the damage is due to cartilage, they turn into cartilage. If the damage is due to soft tissue, they turn into soft tissue. Its the Swiss army knife of treatments." The stem cells are not live embryos, but instead are generated from the placenta and ethically obtained during the C-sections of live births. The women who the cells are taken from are screened and tested for any communicable diseases beforehand. Stem cell therapy uses a minimally invasive technique to inject the … Continue reading

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