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Doctors Use Adult (Not Embryonic) Stem Cells To Grow And Implant Petri-Dish Retina

Posted: Published on October 25th, 2014

The clones are coming! The clones are coming! (Maybe.) Doctors have grown a retina in a petri dish using stem cells from a 70-year-old patients skin and successfully transplanted the retina to her eye at Japan's Riken Center for Developmental Biology. This marks the first time a transplanted organ was grown from skin cells from the recipient and not an embryo, The Globe and Mail reports. Until now, scientists have been mired in a debate regarding the use of embryonic stem cells to create transplant tissue. Using a patients own adult stem cells avoids that controversy and also reduces the chance the patient could reject the transplant. Stem cells hold the promise of curing many diseases, including macular degeneration and Parkinsons. However, there are risks associated with using adult stem cells. Scientists must turn regular adult cells into dividing cells, and there is concern that cells could turn cancerous after transplant. You only need one stem cell left in the graft that could lead to cancer, Dr. Janet Rossant told the The Globe and Mail. Rossant is chief of research at Torontos Hospital for Sick Children and past president of the International Society for Stem Cell Research. The Riken Center … Continue reading →

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Tuffy stem cell therapy patient – Video

Posted: Published on October 25th, 2014

Tuffy stem cell therapy patient Tuffy 2 months after he received Stem Cell Therapy here. He is running around now like nothing happened. I can not believe he was hit by a car and broke his back in 2 places just 2 months ago. By: Noel Berger … Continue reading →

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UCSD Gets $8 Million For Stem Cell Research

Posted: Published on October 25th, 2014

UC San Diego has been named an "alpha clinic" for the clinical study of stem cells, and the distinction comes with $8 million in research grants. Stem cell therapies represent a new way of treating disease by regenerating damaged tissues and organs. Spokesmen for the UCSD school of medicine say the alpha clinic will focus on clinical trials in humans, not just basic research based on animals. The decision to make UCSD an alpha clinic was announced Friday by the California Institute for Regenerative Medicine, which was created by California voters after they approved $3 billion for stem cell funding in 2004. Everything we do has one simple goal, to accelerate the development of successful treatments for people in need, said C. Randal Mills, CIRM president and CEO. Catriona Jamieson, professor of medicine at UC San Diego School of Medicine, is the alpha clinic grants principal investigator. She said the clinic will provide needed infrastructure for first-in-human stem cell-related clinical trials. "It will attract patients, funding agencies and study sponsors to participate in, support and accelerate novel stem cell clinical trials and ancillary studies for a range of arduous diseases, Jamieson said. The university has already announced human stem cell … Continue reading →

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Scientists Create Toxin Secreting Stem Cells To Fight Brain Tumors

Posted: Published on October 25th, 2014

A team of Harvard Stem Cell Institute researchers at Massachusetts General Hospital has successfully engineered stem cells to produce toxins that can kill cancerous cells, turning them into lethal weapons to in the war against brain tumors. Their study was published online in the journal Stem Cells Friday. For years, scientists have attempted to create cells that would not only kill cancerous cells but also do it without harming themselves or surrounding healthy cells. The genetically engineered stem cells created by the researchers in Boston were reportedly able to do so, making the development a potential milestone in the field of cancer treatment. Now, we have toxin-resistant stem cells that can make and release cancer-killing drugs, Khalid Shah, a co-author of the study and the director of the molecular neurotherapy and imaging lab at Massachusetts General Hospital and Harvard Medical School, said in a statement. Cancer-killing toxins have been used with great success in a variety of blood cancers, but they dont work as well in solid tumors because the cancers arent as accessible and the toxins have a short half-life. Based on experiments conducted on mice, the results were very positive, Shah said. After doing all of the molecular … Continue reading →

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UC San Diego Named Stem Cell "Alpha Clinic"

Posted: Published on October 25th, 2014

Contact Information Available for logged-in reporters only Newswise In a push to further speed clinical development of emerging stem cell therapies, Sanford Stem Cell Clinical Center at UC San Diego Health System was named today one of three new alpha clinics by the California Institute for Regenerative Medicine (CIRM), the states stem cell agency. The announcement, made at a public meeting in Los Angeles of the CIRM Governing Board, includes an award of $8 million for each of three sites. The other alpha grant recipients are the City of Hope hospital near Los Angeles and University of California, Los Angeles. A UC San Diego alpha clinic will provide vital infrastructure for establishing a comprehensive regenerative medicine clinical hub that can support the unusual complexity of first-in-human stem cell-related clinical trials, said Catriona Jamieson, MD, PhD, associate professor of medicine at UC San Diego School of Medicine, deputy director of the Sanford Stem Cell Clinical Center, director of the UC San Diego Moores Cancer Center stem cell program and the alpha clinic grants principal investigator. The designation is essential in much the same manner that comprehensive cancer center status is an assurance of scientific rigor and clinical quality. It will attract … Continue reading →

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Family First: Calming the symptoms of severe eczema

Posted: Published on October 25th, 2014

SHREVEPORT, LA (KSLA) - October is National Eczema Awareness month. Eczema, medically known as Atopic Dermatitis, is an itchy red rash that can appear all over the body. Eczema can appear on the elbows or behind the knees, for newborns it often appears on the face. There is no cure for this skin ailment and the severity varies from person to person. A Shreveport mother says this common medical condition caused her young son to go from scratching to biting and now bleeding. If you look closely at two year old Karsyn Lebum's hands and knees, you can still see subtle signs of this skin issue that causes him a great deal of discomfort. Myesha Newton, Karsyn's mother, says watching her son scratch to the point of bleeding is painful to endure. "It's basically covered all of his body except for his face, he scratches all night like right now his hands are so scratched that they bleed,"says Newton. "Every night is miserable because he is scratching all night. He'll just wake up in the middle of the night scratching and will want you to scratch his back or he'll scratch his knee's until they bleed, he does just non … Continue reading →

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For brain hemorrhage, risk of death lower at high-volume hospitals

Posted: Published on October 25th, 2014

For patients with a severe type of stroke called subarachnoid hemorrhage (SAH), treatment at a hospital that treats a high volume of SAH cases is associated with a lower risk of death, reports a study in the November issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. After adjustment for other factors, the mortality rate after SAH is about one-fifth lower at high-volume hospitals, according to the report by Dr. Shyam Prabhakaran of Northwestern University, Chicago and colleagues. They write, "Our data suggest that experienced centers may provide more optimized care for SAH patients." Hospital Volume Linked to SAH Mortality Using data from a nationwide quality improvement program (the Get With the Guidelines-Stroke registry), the researchers identified nearly 32,000 patients with SAH treated at 685 US hospitals between 2003 and 2012. Subarachnoid hemorrhage is a type of stroke in which there is bleeding into the brain, most commonly caused by a ruptured aneurysm. The study compared mortality rates and other outcomes for patients treated at hospitals with different volumes of SAH patients. The number of SAH cases treated per year ranged from as … Continue reading →

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UC San Diego named stem cell 'alpha clinic'

Posted: Published on October 24th, 2014

PUBLIC RELEASE DATE: 23-Oct-2014 Contact: Scott LaFee slafee@ucsd.edu 619-543-6163 University of California - San Diego @UCSanDiego In a push to further speed clinical development of emerging stem cell therapies, Sanford Stem Cell Clinical Center at UC San Diego Health System was named today one of three new "alpha clinics" by the California Institute for Regenerative Medicine (CIRM), the state's stem cell agency. The announcement, made at a public meeting in Los Angeles of the CIRM Governing Board, includes an award of $8 million for each of three sites. The other alpha grant recipients are the City of Hope hospital near Los Angeles and University of California, Los Angeles. "A UC San Diego alpha clinic will provide vital infrastructure for establishing a comprehensive regenerative medicine clinical hub that can support the unusual complexity of first-in-human stem cell-related clinical trials," said Catriona Jamieson, MD, PhD, associate professor of medicine at UC San Diego School of Medicine, deputy director of the Sanford Stem Cell Clinical Center, director of the UC San Diego Moores Cancer Center stem cell program and the alpha clinic grant's principal investigator. "The designation is essential in much the same manner that comprehensive cancer center status is an assurance of … Continue reading →

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UCLA and UCI Awarded $8M Grant to Launch Collaborative Stem Cell Clinic "Center of Excellence"

Posted: Published on October 24th, 2014

Contact Information Available for logged-in reporters only Newswise In a first-of-its-kind collaboration, the University of California, Los Angeles, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and University of California, Irvine Sue & Bill Gross Stem Cell Research Center received a five year $8M grant from the California Institute of Regenerative Medicine (CIRM), the states stem cell agency, to establish a CIRM Alpha Stem Cell Clinic center of excellence to conduct clinical trials for investigational stem cell therapies and provide critical resources and expertise in clinical research. The $8M grant was one of three awarded today by CIRM as part of the CIRM Alpha Stem Cell Clinics (CASC) Network Initiative. The joint UCLA/UCI award under the direction of Dr. John Adams, a member of the UCLA Broad Stem Cell Research Center and professor in the department of orthopaedic surgery, will accelerate the implementation of clinical trials and delivery of stem cell therapies by providing world-class, state-of-the-art infrastructure to support clinical research. CIRM grant reviewers lauded the UCLA/UCI Consortiums impressive and multidimensional team of experienced personnel that will expand access to patients, attracting national and international clinical trials and accelerating future trials in the pipeline. The initial … Continue reading →

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UCSD, other stem cell clinics get millions

Posted: Published on October 24th, 2014

UCSD oncologist/researcher Catriona Jamieson is principal investigator for the university's $8 million stem cell grant. (See correction note at end). To speed up the quest to bring stem cell therapies to patients, a state agency on Thursday granted $8 million each to three academic medical centers pursuing "translational" work -- UC San Diego, UC Los Angeles and City of Hope in Duarte. The California Institute for Regenerative Medicine voted 10-1 to fund the "alpha" stem cell clinics, which are intended to bring stem cell treatments to the public. UC San Diego's proposal supports two stem cell-based clinical trials, both already underway. Catriona Jamieson, an oncologist at the university, is the principal investigator for the grant. One, a treatment for Type 1 diabetes, was developed by San Diego's ViaCyte. The other, for spinal cord injuries is being conducted by Neuralstem of Germantown, Md. In October, UCSD treated the first patient in the trial at the university's Sanford Stem Cell Clinical Center. The stem cell agency, commonly called CIRM, has focused heavily on basic research since its founding by California voters in 2004. But in recent years, the public has become more anxious to see the fruits of $3 billion in bond … Continue reading →

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