Women of Latin American descent, particularly those with indigenous ancestry, may carry a genetic variant that protects them from breast cancer. Previous epidemiological studies have shown that Latinas seem to be less susceptible to developing breast cancer than women of other ethnicities. Now an international group of scientists, led by UCSF researchers, have identified the spot on the DNA sequence responsible for that protective effect. The research is still a long way from making testing for the variant available. Scientists still have a lot more work to do to figure out what the variant means and exactly how it interacts with the body to reduce breast cancer risk. Its good news in a very general sense. But ... I dont think anyone should stop mammograms because of the variant, said Laura Nejerman, lead author of the study published earlier this week and assistant professor of medicine at UCSF. Now what we are trying to do is think of how best to incorporate this genetic information with other risk-factor information to better provide a picture of breast cancer risk. But the discovery highlights the existence of genetic risk factor differences between racial groups and ethnicities, and the advent of genome decoding … Continue reading
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