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NeuroSigma, US Veterans Administration (VA) enter into cooperative research and development agreement

Posted: Published on October 16th, 2014

Published 16 October 2014 NeuroSigma a California-based life sciences company focused on commercialization of its non-invasive Monarch eTNS System for the treatment of neurological and neuropsychiatric disorders, has entered into a Cooperative Research and Development Agreement (CRADA) with the U.S. Veterans Affairs (VA) for a clinical trial to evaluate the benefits of non-invasive, external Trigeminal Nerve Stimulation (eTNS) for patients with traumatic brain injury (TBI) in a Phase I clinical trial. Jean-Philippe Langevin, M.D., an expert in neurotrauma and a neurosurgeon at the Veterans Affairs Greater Los Angeles (VAGLA) medical center, will lead the study as Principal Investigator. The project will enroll U.S. military veterans with TBI in an eight-week treatment protocol, and will examine change in cognitive function and regional brain activity as people receive nightly eTNS treatment at home. TBI is a condition that arises after mechanical injury to the brain. According to the Centers for Disease Control and Prevention, an estimated 5.3 million Americans currently live with TBI-related disability, with an annual total cost in 2010 estimated at $76.5 billion, including $11.5 billion in direct medical costs and $64.8 billion in indirect costs including lost wages, lost productivity, and nonmedical expenditures. The Department of Defense has reported … Continue reading

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Drs. Roger Parkes and R. Clarke Stewart Recognize Dental Hygiene Month by Illustrating the Benefits of Laser Gum …

Posted: Published on October 16th, 2014

Jackson, MS (PRWEB) October 15, 2014 Roger Parkes, DMD, MSD and R. Clarke Stewart, DMD encourage patients in Jackson, MS to celebrate Dental Hygiene Month this October by learning about the LANAP protocol, an FDA-cleared laser gum surgery. This unique procedure cleans away bacteria and infection caused by gum disease without the cutting, scraping and suturing of traditional scalpel surgery. Gum disease has often reached advanced stages by the time patients notice the first symptoms, which include redness, tenderness and bleeding gums. Gum disease, or periodontitis, typically begins with plaque, a sticky paste created by bacteria in the mouth that feeds on acids from food. Plaque hardens to form tartar, which irritates the gums and causes infection below the gum line around the roots of the teeth. Severe gum disease symptoms often include pockets of pus that pull the gums away from the teeth. Good oral hygiene is the primary defense against plaque and tartar, but hormone fluctuations, genetics and tobacco use are risk factors that may make a patient more likely to develop the disease. Drs. Parkes and Stewart are in the minority of periodontists who are qualified to provide patients in Jackson, MS with laser gum surgery as … Continue reading

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Genetic Defect Links Rare Infections to Autoimmune Diseases

Posted: Published on October 16th, 2014

Contact Information Available for logged-in reporters only Newswise (NEW YORK - Oct. 15) A team led by researchers at The Rockefeller University and the Icahn School of Medicine at Mount Sinai has explained the function of key immune protein and solved an international medical mystery, according to a letter published this week in the journal Nature. In previous work, the research team lead had linked small changes in a key gene with a reduced ability to fight off a set of rare bacterial infections. Shortly afterward, a team of Chinese scientists reached out to say they had found three Chinese children with mutated versions of the same gene. Strangely, the Chinese children had no history of the severe bacterial infections, but instead had seizures and unusual calcium deposits in their brains. The disconnect led to the discovery of an immune protein with two seemingly opposing roles: amplifying and tamping down aspects of an immune system response, according the study, published on Sunday, Oct. 12. The roles explained how the protein, or lack of it, could weaken response to an infectious disease in one instance, but contribute to the attack by the immune system on a persons own tissues (autoimmune disease) … Continue reading

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Retinal stem cell study shows promise for therapy

Posted: Published on October 16th, 2014

SAN DIEGO (KUSI) - Macular degeneration is the leading cause of vision loss for people over the age of 50. Scientists have discovered a new therapy that may actually restore sight in those affected. Scientists are excited not only because it worked, and helped some people see clearly again, but also because this study puts a focus on an new kind of stem cell therapy, using skin cells. Macular degeneration causes a blurry or black area in the middle of your field of vision that grows over time, causing more sight loss. There is no cure, but a new study published this week in the journal The Lancet, is giving patients hope. Embryonic stem cells were turned into retinal cells and implanted into the eyes of 18 patients. Vision improved for about half of them. Dr. Andreas said, "This study was primarily to see if these cells would be safe, and the bonus was that some people started to see better." Dr. Andreas Bratyy-Layal and Dr. Suzanne Peterson are stem cell scientists with the Scripps Research Institute. They see this as a major breakthrough. Although this sight study did do that, Dr. Peterson says labs around the country, including here … Continue reading

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Stem cell, regenerative medicine policies to be discussed at Rice's Baker Institute

Posted: Published on October 16th, 2014

Dr. Deepak Srivastava, a leading biomedical research policy expert, will discuss "Stem Cells, Regenerative Medicine and Policy Impediments to the New Future" at Rice University's Baker Institute for Public Policy Oct. 21. The event is free and open to the public, but registration is required. Who: Dr. Deepak Srivastava, the Baker Institute's nonresident scholar for biomedical research policy and the Younger Family Director and senior investigator at the Gladstone Institute of Cardiovascular Disease. Neal Lane, the Malcolm Gillis University Professor, senior fellow in science and technology policy at Rice's Baker Institute for Public Policy and a professor of physics and astronomy, will give introductory remarks. Stem cells and regenerative medicine are exciting and emerging fields of biomedical research, according to event organizers. Proposed applications include treating conditions such as blindness, diabetes and heart disease. Regenerative medicine could also help heal failing organ systems and replace damaged tissue. While these fields hold great promise for medicine, external factors limit and, in some cases, stall research, organizers said. Ethical controversies surrounding human embryonic stem cells, policy issues affecting federal and state funding and regulation, and economic pressures all play a role in determining the future of research. In his presentation, Srivastava will … Continue reading

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Discovery of Repair Process After Heart Attack Suggests Potential for New Treatment Strategy

Posted: Published on October 16th, 2014

Contact Information Available for logged-in reporters only Newswise In a study that could point the way toward a new strategy for treating patients after a heart attack, UCLA stem cell researchers led by associate professor of medicine (cardiology) and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Arjun Deb have discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells (the cells that form blood vessels). The UCLA team also found that a drug could enhance this phenomenon and improve the repair process after a heart attack. The findings are reported in the October 15, 2014 edition of the journal Nature. It is well known that increasing the number of blood vessels in the injured heart following a heart attack improves its ability to heal, said Dr. Deb, the studys senior author. We know that scar tissue in the heart is associated with a poorer prognosis. Reversing or preventing scar tissue from forming has been one of the major challenges of cardiovascular medicine. Heart disease remains a leading cause of death in the United States. Each year in this country, approximately 720,000 people experience a heart … Continue reading

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Kangen Water Testimony – Eczema, Weight Loss, Headaches – Video

Posted: Published on October 15th, 2014

Kangen Water Testimony - Eczema, Weight Loss, Headaches http://www.kckangen.com Office: 913.744.9592 Cell: 913.449.0960 *These statements have not been evaluated by the United States Food and Drug Administration. This product is not intended to diagnose,... By: Kansas City Kangen Water … Continue reading

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Eczema and Your Skin | Eczema Types, Symptoms, Causes, and …

Posted: Published on October 15th, 2014

Eczema is a term for a group of medical conditions that cause the skin to become inflamed or irritated. The most common type of eczema is known as atopic dermatitis, or atopic eczema. Atopic refers to a group of diseases with an often inherited tendency to develop other allergic conditions, such as asthma and hay fever. Eczema affects about 10% to 20% of infants and about 3% of adults and children in the U.S. Most infants who develop the condition outgrow it by their tenth birthday, while some people continue to have symptoms on and off throughout life. With proper treatment, the disease often can be controlled. No matter which part of the skin is affected, eczema is almost always itchy. Sometimes the itching will start before the rash appears, but when it does, the rash most commonly appears on the face, back of the knees, wrists, hands, or feet. It may also affect other areas as well. Affected areas usually appear very dry, thickened, or scaly. In fair-skinned people, these areas may initially appear reddish and then turn brown. Among darker-skinned people, eczema can affect pigmentation, making the affected area lighter or darker. In infants, the itchy rash can … Continue reading

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Dermatitis – Wikipedia, the free encyclopedia

Posted: Published on October 15th, 2014

Dermatitis (from Greek derma "skin" and - -itis "inflammation") or eczema (Greek: ekzema "eruption") is inflammation of the skin. It is characterized by itchy, erythematous, vesicular, weeping, and crusting patches. The term eczema is also commonly used to describe atopic dermatitis[1][2] or atopic eczema.[3] In some languages, dermatitis and eczema are synonyms, while in other languages dermatitis implies an acute condition and eczema a chronic one.[4] The term eczema is broadly applied to a range of persistent skin conditions. These include dryness and recurring skin rashes that are characterized by one or more of these symptoms: redness, skin swelling, itching and dryness, crusting, flaking, blistering, cracking, oozing, or bleeding. Areas of temporary skin discoloration may appear and are sometimes due to healed injuries. Scratching open a healing lesion may result in scarring and may enlarge the rash. Treatment is typically with moisturizers and steroid creams.[3] If these are not effective, creams based on calcineurin inhibitors may be used.[5] The disease was estimated as of 2010 to affect 230 million people globally (3.5% of the population).[6] The term "eczema" refers to a set of clinical characteristics. Classification of the underlying diseases has been haphazard and unsystematic, with many synonyms used to … Continue reading

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Eczema: Read About Symptoms and Medications

Posted: Published on October 15th, 2014

Eczema (Atopic Dermatitis) Eczema Overview The term eczema is derived from the Greek, meaning "to boil out." The name is particularly apt since to ancient medical practitioners it may have appeared that the skin was "boiling." Today the usage is rather imprecise since it is frequently used to describe any sort of dermatitis (inflammatory skin condition). Not all dermatitis is eczematous. All eczematous dermatitis has a similar appearance. Acute lesions are composed of many small fluid-filled structures called vesicles that usually reside on red, swollen skin. When these vesicles break, fluid leaks out, causing characteristic weeping and oozing. When the fluid dries, it produces a thin crust. In older lesions, these vesicles may be harder to appreciate, but an examination of the tissue under the microscope will reveal their presence. Eczematous dermatitis has many causes. One of the most common is a condition called atopic dermatitis. Often those using the term eczema are referring to atopic dermatitis. Although atopy refers to a lifelong inherited (genetic) predisposition to inhalant allergies such as asthma and allergic rhinitis (hay fever), atopic dermatitis is not an allergic disease. Atopic patients are likely to have asthma, hay fever, and dermatitis. Atopy is a very common … Continue reading

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