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Ulcerative Colitis: Facts on Symptoms, Treatment and Diet

Posted: Published on October 15th, 2014

Ulcerative Colitis Ulcerative Colitis Overview Ulcerative colitis (UC) is an acute or chronic inflammation of the membrane that lines the colon (the large intestine or large bowel). The inflammation occurs in the inner most layer of the colon and may result in the formation of sores (ulcers). Ulcerative colitis rarely affects the small intestine except for the lower most section, called the terminal ileum. The inflammation makes the colon empty frequently causing diarrhea. Ulcers form in places where the inflammation has killed the cells lining the colon. The ulcers bleed and produce pus and mucus. Symptoms of ulcerative colitis include abdominal pain, diarrhea, rectal bleeding, a recurrent urge to have a bowel movement (tenesmus), lack of appetite, fever, and fatigue. Abdominal pain, diarrhea, and bloody bowel movements are the hallmark of the disease. The disease initially causes inflammation in the rectum and may gradually spread to involve the whole colon. If just the rectum is involved, it is referred to as ulcerative proctitis. Ulcerative colitis is one of the inflammatory bowel diseases (IBD), the other is Crohn's disease. Medically Reviewed by a Doctor on 11/14/2012 Go here to read the rest: Ulcerative Colitis: Facts on Symptoms, Treatment and Diet … Continue reading →

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GW Pharma Reports Preliminary Topline Results Of Ulcerative Colitis Trial

Posted: Published on October 15th, 2014

By RTT News, October 14, 2014, 07:13:00 AM EDT (RTTNews.com) - GW Pharmaceuticals Plc. ( GWPH ) (GWP.L) Tuesday announced preliminary topline results from a Phase 2a ulcerative colitis trial to be presented today at the company's R&D Day event in New York City. The Phase 2a pilot trial was a 10-week randomized, double-blind, placebo controlled study of GWP42003 extract, which features Cannabidiol or CBD as the primary cannabinoid and which also contains Tetrahyrdocannabinol or THC and other cannabinoid and non-cannabinoid components. The trial included 60 adult patients with ulcerative colitis who had not been able to gain remission from the condition, despite first line treatment with salicylates, and in some cases immunosuppressive therapy. GWP42003 was given as a twice daily oral capsule in a dose titration regimen, with an upper target dose of 250 mg twice daily. Due to the pilot nature of the study, and the small patient population, the significance value was set at p=0.1. The primary endpoint of this study was the percentage of participants achieving remission quantified by the MAYO score and included a range of secondary measures to determine whether GWP42003 has a positive benefit for subjects on symptom control. The study included 60 … Continue reading →

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Immune Cells May Help Treat Muscular Dystrophy, UCSF-Led Team Finds

Posted: Published on October 15th, 2014

A scientific team led by UC San Francisco researchers found that regulatory T cells (Tregs), a specialized subset of immune cells, suppress inflammation and muscle injury in a mouse model of Duchenne muscular dystrophy (DMD). The scientists said that Tregshave potential as therapeutic agents for DMD, an inherited disease that strikes children almost always boys and leads to progressive muscle degeneration and early death. They published their findings online October 15, 2014, inScience Translational Medicine. The researchers discovered that Tregs, which dampen immune responses, are found in the muscles of mice and humans with genetic mutations that lead to the development of muscular dystrophy, but not in the muscles of healthy wild-type mice or healthy humans. The finding indicates that the Tregsappear in muscle in response to the muscle injury, said lead investigator S. Armando Villalta, PhD, a postdoctoral fellow at the UCSF Diabetes Center. When we remove Tregsfrom the muscles of the genetically engineered mice, the disease gets worse, said Villalta. When we boost the cells in mice, we reduce inflammation and muscle injury. According to Villalta, the healing effect is due in large part to interleukin-10 (IL-10), an anti-inflammatory protein produced by Tregsand other immune-regulating cells. IL-10 is … Continue reading →

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Northwest Epilepsy Conferences to Highlight Marijuana …

Posted: Published on October 15th, 2014

SEATTLE, Oct. 14, 2014 /PRNewswire-USNewswire/ -- The Epilepsy Foundation Northwest announces two regional conferences in November celebrating National November Epilepsy Awareness Month. The conferences will be held in Seattle, WA and Spokane, WA, and are free and open to the public. The conference in Seattle will be on Saturday, November 8 at the Wright Auditorium at Seattle Children's Hospital from 8:30 am to 4:30 pm. Keynote speaker, Dr. Jeffrey Bucchalter, Director of the Comprehensive Children's Epilepsy Center at Alberta Children's Hospital. Dr. Bucchalter will speak on Sudden Unexpected Death in Epilepsy (SUDEP) A Conversation Based on Risk and Empathy. SUDEP is the leading cause of premature death among people with epilepsy, and topic gaining more attention in research and patient-provider relationships. Use of marijuana in treatment of epilepsy, "Medical Marijuana: Current Impacts on Epilepsy Treatment" will be presented by Dr. Russell Saneto of Seattle Children's Hospital. Other conference presentation topics include "Sleep and Impacts on Epilepsy," "Anti-Seizure Medication," "Infants/Preschool Age Children with Epilepsy," and a panel of medical professionals for a question and answer period. To register for the Seattle Conference go to: http://www.SeattleConference.org. (The Seattle Conference will also be available in webcast.) The conference in Spokane will be held … Continue reading →

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State panel OKs cannabis oil ID cards; can't apply for them yet

Posted: Published on October 15th, 2014

DES MOINES | A legislative panel Tuesday cleared state rules to take effect Jan. 30 governing registration cards for Iowans authorized to possess marijuana-derived cannabis oil for treatment of epilepsy. However, Deborah Thompson, policy adviser for the Iowa Department of Public Health, said her agency and the state Department of Transportation may not be in a position to actually issue the photo ID registration cards until a later date after the rules have taken effect. DOT officials have been working with a vendor to produce the cards, part of a new state law that allows limited access to medical cannabidiol, she said. State officials are treating the cards as a priority project as they push for a launch date to physically issue the cards. We just want to make sure that all of the pieces are there, Thompson said. I would like to think well know closer to the date what everything looks like. It is likely that the health agency will post an application form online in advance of the card issuance so patients and parents of minor patients can submit the information needed from a licensed neurologist to qualify. However, the bigger issue facing families of epileptic patients … Continue reading →

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Neuravi Receives US Patents for Neurovascular Clot Capture and Retrieval

Posted: Published on October 15th, 2014

Galway, Ireland (PRWEB) October 15, 2014 Neuravi, a developer of innovative minimally invasive stroke therapy solutions, announced today that the U.S. Patent Office has approved two patents covering its therapeutic platform for the endovascular treatment of acute ischemic stroke. The granting of U.S. Patent #8,852,205 Clot Retrieval Device for Removing Occlusive Clot from a Blood Vessel and U.S. Patent #8,777,976 B2 Clot Capture Systems and Associated Methods expands Neuravis US granted portfolio to 33 patents. These new patents disclose unique design elements intended to enable both clot disengagement and capture and so facilitate the protected removal of hazardous clot from the brain.The CE-marked Embotrap Revascularization System incorporates these advanced features into its design. According to David Vale, Chief Technology Officer for Neuravi, the company has established its extensive portfolio by a combination of external licensing and internal R&D. This approach has given us a great combination of very early priority filings on the base technology as well as strong protection on the more advanced 3rdgeneration features. The extensive Neuravi patent portfolio continues to be strengthened by our R&D teams commitment to developing technologies that tackle some of the most daunting clinical challenges in treating this patient population, said David. The … Continue reading →

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Effects of high-risk Parkinson's mutation are reversible

Posted: Published on October 15th, 2014

PUBLIC RELEASE DATE: 15-Oct-2014 Contact: Amy Pullan a.l.pullan@sheffield.ac.uk 01-142-229-859 University of Sheffield @sheffielduni Researchers from the University of Sheffield have found vital new evidence on how to target and reverse the effects caused by one of the most common genetic causes of Parkinson's. Mutations in a gene called LRRK2 carry a well-established risk for Parkinson's disease, however the basis for this link is unclear. The team, led by Parkinson's UK funded researchers Dr Kurt De Vos from the Department of Neuroscience and Dr Alex Whitworth from the Department of Biomedical Sciences, found that certain drugs could fully restore movement problems observed in fruit flies carrying the LRRK2 Roc-COR Parkinson's mutation. These drugs, deacetylase inhibitors, target the transport system and reverse the defects caused by the faulty LRRK2 within nerve cells. The study is published today (15 October 2014) month in Nature Communications. Dr De Vos, a Lecturer in Translational Neuroscience at the world-leading Sheffield Institute for Translational Neuroscience (SITraN), said: "Our study provides compelling evidence that there is a direct link between defective transport within nerve cells and movement problems caused by the LRRK2 Parkinson's mutation in flies." Co-investigator Dr Alex Whitworth explained: "We could also show that these neuronal … Continue reading →

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Magnetic stimulation gains in depression treatment

Posted: Published on October 15th, 2014

A machine that sends magnetic pulses into a patient's brain has become the new frontier of depression treatment, promising to ease symptoms for those who have found little relief from medication or talk therapy. The treatment, known as transcranial magnetic stimulation, or TMS, is part of a wave of technologies that attempt to jolt the brain back to health. It caught on quickly after the Food and Drug Administration approved its use six years ago, and more than 25 Chicago-area hospitals and psychiatrists now use the devices. Though some have questioned the technology's effectiveness, more insurance companies are starting to cover it, helping with a price tag that can reach $10,000 for six weeks of treatment. "What this does is raises (your mood) up to normal," said a 55-year-old woman from the western suburbs after finishing a treatment session at Linden Oaks at Edward in Naperville. "You can operate." Stimulative brain therapies have been around for decades, with the best known being electroconvulsive therapy, a technique that uses an electric current to cause a seizure. It was portrayed as a mind-erasing menace in the movie "One Flew Over the Cuckoo's Nest," though psychiatrists say the procedure is safe today. Other … Continue reading →

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Gino D'Acampo donates almost 10,000 to three-year-old suffering from cerebral palsy

Posted: Published on October 15th, 2014

Gino D'Acampo has donated almost 10,000 to a young boy with cerebral palsy[ITV2] The Italian star has decided to help three-year-old Ollie Dodds, from Lichfield, who suffers from spastic quadriplegic cerebral palsy which prevents him from walking, standing and even sitting up straight. After researching the condition, Ollie's parents Hayley Smith and James Dodds discovered Selective Dorsal Rhizotomy (SDR) treatment, which can benefit children with cerebral palsy. Unfortunately, the 36,000 procedure is not funded by the NHS which left Hayley, 23, and James, 31, with a huge bill to help transform their son's life. The couple decided to launch the Operation Ollie appeal to find 50,000 to pay for the treatment as well as travel costs to St Louis Children's Hospital in Missouri in the US which specialises in SDR. Hayley Smith and James Dodd with their three-year-old son Ollie [BPM MEDIA] We went to Bolton Food Festival where he was giving a cookery class to thank him in person. He was such a nice guy, very genuine and made time for us Hayley Smith The former I'm A Celebrity Get Me Out Of Here contestant pledged 5,000 to the appeal a few weeks ago and followed it up with … Continue reading →

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TV chef Gino D'Acampo backs disabled Lichfield boy's quest for surgery

Posted: Published on October 15th, 2014

TV chef Gino DAcampo has donated almost 10,000 to help a Midland couple fund an operation that could enable their disabled son to walk. Three-year-old Ollie Dodds, from Lichfield, suffers from spastic quadriplegic cerebral palsy which prevents him from walking, standing and even sitting up straight. After researching the condition, Ollies parents Hayley Smith and James Dodds discovered Selective Dorsal Rhizotomy (SDR) treatment, which can benefit children with cerebral palsy. Gino D'Acampo in the Citrus groves of the Amalfi Coast The 36,000 procedure is not funded by the NHS leaving Hayley, 23, and James, 31, with a huge bill to help transform their sons life. They launched the Operation Ollie appeal to find 50,000 to pay for the treatment as well as travel costs to St Louis Childrens Hospital in Missouri, USA, which specialises in SDR. Italian celebrity Gino, a regular on ITVs This Morning, pledged 5,000 to the appeal a few weeks ago and followed it up with a donation of 4,250 earlier this month. Its very touching, said Hayley. We have just been amazed by his generosity. We went to Bolton Food Festival where he was giving a cookery class to thank him in person. Read the original: … Continue reading →

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