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Parkinson’s disease Treatments and drugs – Diseases and …

Posted: Published on October 15th, 2014

Parkinson's disease can't be cured, but medications can help control your symptoms, often dramatically. In some later cases, surgery may be advised. Your doctor may also recommend lifestyle changes, especially ongoing aerobic exercise. In some cases, physical therapy that focuses on balance and stretching also is important. Medications can help you manage problems with walking, movement and tremor by increasing your brain's supply of dopamine. However, dopamine can't be given directly, as it can't enter your brain. You may have significant improvement of your symptoms after beginning Parkinson's disease treatment. Over time, however, the benefits of drugs frequently diminish or become less consistent, although symptoms usually can continue to be fairly well controlled. Your doctor may prescribe medications, which may include: Carbidopa-levodopa. Levodopa, the most effective Parkinson's disease medication, is a natural chemical that passes into your brain and is converted to dopamine. Levodopa is combined with carbidopa (Parcopa, Sinemet), which protects levodopa from premature conversion to dopamine outside your brain, which prevents or lessens side effects such as nausea. In Europe, levodopa is combined with a similar substance, benserazide (Madopar). Side effects may include nausea or lightheadedness (orthostatic hypotension). After years, as your disease progresses, the benefit from levodopa … Continue reading

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American Parkinson Disease Association call for applicants for prestigious George C. Cotzias Memorial Fellowship to be …

Posted: Published on October 15th, 2014

New York, NY (PRWEB) October 14, 2014 The American Parkinson Disease Association is pleased to announce the application process for this prestigious award is now open. The George C. Cotzias, MD Memorial Fellowship was developed by the American Parkinson Disease Association (APDA) in 1979 to honor Dr. Cotzias who was a pathfinder in the pharmacologic exploration of brain functions and in the treatment of Parkinson's disease with levodopa. The goal of the award, which provides financial support to recipients of $80,000 per year for 3-years, is to stimulate young neurologists to follow in Dr. Cotzias footsteps in understanding new discoveries that will lead to advances in treating neurological movement disorders. The fellowship is awarded to promising young neurologists to help them establish careers in research, teaching and patient services relevant to the problems, causes, prevention, diagnosis and treatment of Parkinson's disease and related neurological movement disorders. I recognize the APDA Cotzias Fellowship as one of the most important events in establishing my long-term commitment to Parkinson disease research. I received my award in 1996, which was a crucial moment in my career, states David G. Standaert, MD, PhD, Chair of the APDA Scientific Advisory Board (SAB) and John N. Whitaker … Continue reading

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Cynapsus Therapeutics Inc.: Cynapsus Therapeutics' Phase 2 Drug Candidate for Parkinson's Chosen as One of the Top Ten …

Posted: Published on October 15th, 2014

Criteria for selection of the Top 10 Neurology Projects to Watch are: Large market, large unmet need, with increasing opportunity History of the molecule and drug Strong science Strong company Diversity of indications Potential for new opportunities beyond the initial indications Multi-level partnering opportunities, i.e., biotech to biotech as well as pharma to biotech Over one million people in the U.S. and an estimated 4 to 6 million people globally suffer from Parkinson's disease. Parkinson's disease is a chronic and progressive neurodegenerative disease that impacts motor activity, and its prevalence is increasing with the aging of the population. OFF episodes are a complication of Parkinson's disease that leave patients rigid and unable to move and communicate. Approximately 25% to 50% of Parkinson's patients experience OFF episodes, which can occur 1 to 6 times daily and last between 30 and 120 minutes. Today, apomorphine is the only drug that can rapidly convert a patient from OFF (unable to move) to ON (fully functional). Unfortunately for Parkinson's patients, apomorphine is primarily only available as a needle injection, which can be painful and difficult to administer. Read the original: Cynapsus Therapeutics Inc.: Cynapsus Therapeutics' Phase 2 Drug Candidate for Parkinson's Chosen as One … Continue reading

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Timing Is Key for Traumatic Brain Injury Treatment

Posted: Published on October 15th, 2014

Contact Information Available for logged-in reporters only Newswise Researchers at the University of Adelaide have discovered two potential treatments for traumatic brain injury that are most effective when given at different stages after the injury has occurred. Laboratory studies conducted in the University's School of Medical Sciences have confirmed that changes in brain water channels over time play a critical role in traumatic brain injury. For his PhD at the University, researcher Dr Joshua Burton tested two compounds that alter the natural flow of water activity in and out of the brain. He found that recovery from brain injury can be greatly assisted when these compounds are given at the right times. Dr Burton's work could point to the potential development of new drugs as well as new approaches to preventing brain damage and death. The research also has implications for treatment of brain swelling after stroke. "One of the serious consequences of traumatic brain injury is an increase in brain moisture content and associated brain swelling, which significantly impacts patients' neurological outcomes. This swelling can occur for days after the initial injury and is frequently life-threatening," Dr Burton says. "The water channels normally function to protect the brain, but … Continue reading

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Brain injury similarities in troops, football players spur collaboration, research

Posted: Published on October 15th, 2014

The gridiron and the battlefield have little in common, but brain injuries plaguing combat veterans and former football players has doctors and veterans advocates eager to bring brain injury research out of the dark ages. Its too early to determine the similarities and differences of brain trauma between veterans and football players. In the days immediately after their injuries, both are treated the same way: with rest and treatment of pain and other symptoms. SEE ALSO: New Army helmet fails brain injury protection test, may cause worse injuries We still dont know what the complete answer is, said Dr. Ann McKee, the chief of neuropathology in the VA Boston Healthcare System and a professor of neurology and pathology at the Boston University School of Medicine. I can tell you there are some parallels, and also some differences, but its very early on in research. Mike Helm, the new national commander of the American Legion, said its time for researchers to learn from one another. He said new Veterans Affairs Secretary Robert McDonald has the same idea. He wants to have a summit, Mr. Helm said. The veteran population is not the only one suffering from traumatic brain injury and post-traumatic … Continue reading

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New hope for battered homeless women in the Valley

Posted: Published on October 15th, 2014

PHOENIX -- Battered and beaten women living on the streets can now get much needed treatment for traumatic brain injuries. The Barrow Concussion and Brain Injury Center has created a unique program to treat homeless women who have suffered brain injuries due to domestic violence. "Injuries that result in thinking problems, injuries that result in memory problems, injuries that result in headaches and disability, injuries that result in epilepsy and seizures," Dr. Javier Cardenas with the Barrow Concussion and Brain Injury Center said. Cardenas said the center has identified a three-way link between those types of injuries, homelessness and domestic violence. "Many of those injuries are simply unreported," he said. "They don't go to the emergency room, they to their doctor's office and unless there hospitalized because of a life-threatening injury, they seek no medical care." The Barrow Concussion and Brain Injury Center is now working with homeless women to help with any and all domestic violence related injuries that may have caused brain damage. "What we hope to do is identify the injuries in these people who've suffered them as a result of domestic violence and provide them with treatment to address the issues," Cardenas said. So far, the … Continue reading

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Michael Schumacher's brain injury may have been due to GoPro camera on helmet: French journalist

Posted: Published on October 15th, 2014

By Rachael Brown October 15, 2014, 8:15 am Shares in camera company GoPro have taken a dive after a French journalist suggested it might have been to blame for Michael Schumacher's brain injury. The 45-year-old slammed his head on a rock while skiing with his son and friends in the French Alps in December. He emerged from a medically induced coma in June and is receiving treatment at his Swiss home. French grand prix commentator Jean-Louis Moncet told a European radio station it was not the accident, but the camera attached, that left Schumacher in a coma. "The problem for Michael was not the hit, but the mounting of the GoPro camera that he had on his helmet that injured his brain," Mr Moncet told Europe 1. The French journalist was reported to have spoken to Schumacher's son Mick, but he later denied this in a tweet. Schumacher's helmet shattered but the camera was undamaged in the accident. London's Telegraph newspaper has previously reported that experts from ENSA, a ski and climbing school in Chamonix, have run tests to see if a solid object between a rock and a helmet would cause the helmet to smash. No confirmation has been … Continue reading

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Many Parents Need to Educate Themselves About Concussions

Posted: Published on October 15th, 2014

Latest Prevention & Wellness News FRIDAY, Oct. 10, 2014 (HealthDay News) -- Parents' lack of knowledge about concussion may hinder youngsters' treatment and recovery, two new studies suggest. One study included a survey of 511 parents of children aged 5 to 18 who suffered a head injury. Only about half of the parents knew that a concussion was a brain injury that could cause symptoms such as headache or difficulty concentrating. Ninety-two percent knew that they should stop their child from playing sports and see a doctor if they suspected their youngster had a concussion, but only 26 percent knew about guidelines on when their child could resume sports and school work. The findings were to presented Friday at the American Academy of Pediatrics (AAP) annual meeting, in San Diego. "Our study showed that the vast majority of parents knew what to do if they suspected a concussion in their child, and in most cases understood the clinical importance of this injury as a brain injury," study author Dr. Kirstin Weerdenburg, a pediatric emergency medicine fellow at Hospital for Sick Children in Toronto, said in an AAP news release. "The study also highlights that a physician visit shortly after the … Continue reading

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Man has two cars stolen on same day while wife gets treatment for MS

Posted: Published on October 15th, 2014

SAN JOSE, Calif. -- The first of Daniel Stewart's two cars was stolen out of the hospital parking lot and his second car was stolen not long after. "What could possibly happen to make things any worse you know? And then this happens," said Stewart. For Stewart, it's been a tough few weeks. He learned his wife Jennifer has MS. Then while at her side at Good Samaritan Hospital Sunday, he lost his keys. Whoever found them not only stole his car from the hospital lot, but also the family's second car parked in their driveway. "They probably got in my car. The only thing in my glove box would have been my registration and my insurance. It has my address right on it. Both keys are on the key ring, they probably drove straight here and got the other car," said Stewart. Both cars are the same make and model, a 2013 Chevy Cruze LS. Monday night, San Jose police found one of them with minimal damage, which is a bright spot in what's been a nightmare ordeal. The car thief found Stewart's wallet, which he left in his trunk. So not only is he dealing with stolen cars, … Continue reading

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Madeleine Stowe Opens Up About Father's Battle With MS

Posted: Published on October 15th, 2014

Oct 14, 2014 1:59pm Tommaso Boddi/Getty Images Madeleine Stowe has revealed for the first time her late fathers battle with multiple sclerosis and how, as a child, she helped take care of him. Stowe is sharing her story as part ofbiotech giant Genzymes new campaign to educate and empower people living with MS. Back in the day, during my fathers time there were no approved treatment options, she said in a video for the campaign, Lights, Camera, Taken Action on MS. Myearliest memory might have been 2, 3 years old and hearing hes not doing quite well. Stowe said, There wasnt a high level of anxiety around it. It was, Okay this is different, This is strange. We were childrenbut there was this shadow. The shadow was MS. And we knew very little about it back in those days. There were no alternatives at the time. There was just the disease. Watch: Madeleine Stowe on Characters Queen of Mean Reputation Madeleine Stowe: Scheming Vixen On-Screen, Philanthropist in HaitiOff-Screen The Revenge star was the oldest of three children. I became with my mother, my fathers nursemaid, she recalled. Sometimes I felt like I lacked mercy and I judged him when I … Continue reading

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