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Giant leap made in effective Type 1 diabetes treatment

Posted: Published on October 11th, 2014

Scientists believe they have made a giant leap forward in the quest to find an effective treatment for Type 1 diabetes. Using human embryonic stem cells as a starting point, experts have for the first time been able to produce human insulin-producing beta cells equivalent in almost every way to normally functioning beta cells in the kind of massive quantities needed for cell transplantation and pharmaceutical purposes. Doug Melton, Xander University professor at Harvard University, who led the work, said he hoped to have human transplantation trials using the cells under way within a few years. The stem cell-derived beta cells are currently undergoing trials in animal models, including non-human primates. Prof Melton, who is also co-director of the Harvard Stem Cell Institute, said the device being tested had so far protected beta cells implanted in mice from immune attack for many months. There have been previous reports of other labs deriving beta cell types from stem cells, he said. No other group has produced mature beta cells as suitable for use in patients. The biggest hurdle has been to get to glucose-sensing, insulin-secreting beta cells, and thats what our group has done. We are now just one pre-clinical step … Continue reading

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Could this stem cell breakthrough offer an end to diabetes?

Posted: Published on October 11th, 2014

Research into a cure for diabetescould result in an end to insulin injections It has beenhailed as the biggest medical breakthrough since antibiotics Harvard researcher Doug Melton promised his children he'd find a cure Treatment involves making insulin-producing cells from stem cells Scientistshope to have human trials under way within a 'few years' By Fiona Macrae for the Daily Mail Published: 17:41 EST, 9 October 2014 | Updated: 04:45 EST, 10 October 2014 2.9k shares 204 View comments Scientists have hailed stem-cell research into a cure for diabetes as potentially the biggest medical breakthrough since antibiotics. It could result in an end to insulin injections, and to the disabling and deadly complications of the disease, such as strokes and heart attacks, blindness and kidney disease. The treatment, which involves making insulin-producing cells from stem cells, was described as a 'phenomenal accomplishment' that will 'leave a dent in the history of diabetes'. Scroll down for video Read this article: Could this stem cell breakthrough offer an end to diabetes? … Continue reading

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Stem Cell Treatment for SCI Documentary Part 7 – Video

Posted: Published on October 11th, 2014

Stem Cell Treatment for SCI Documentary Part 7 via YouTube Capture. By: frnkmckenzie … Continue reading

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Analytical Stem Cell – Video

Posted: Published on October 11th, 2014

Analytical Stem Cell Analytical Stem Cell is currently profitable within a $100 billion traveling treatment market, that is growing by 30% annually, and is targeting the lucrative anti-aging market which is anticipated... By: Analytical Stem Cell Investor … Continue reading

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Successful stem cell treatment in mice could one day help cure type one diabetes

Posted: Published on October 11th, 2014

On Thursday important research on stem cells and type 1 diabetes, done by professor Doug Melton, was published in the journal Cell. The results of this study have both wide and very personal implications. Two decades ago, National Geographic reported, the current Harvard professor and stem cell researcher vowed to cure type 1 diabetes. His infant son had just been diagnosed with the disease. Professor Meltons efforts redoubled when, at age 14, his daughter was also diagnosed with the autoimmune disorder. With the publication of this research he may have taken a step towards helping cure this disease. According to National Geographic, Melton has created a virtually unlimited supply of the cells that are missing in people with type 1 diabetes. Type 1 diabetes, which is often diagnosed in children or young adults, affects around three million Americans. Type 1 diabetes is a chronic condition in which the pancreas produces little or no insulin, a hormone needed to allow sugar (glucose) to enter cells to produce energy, according to Mayo Clinic. This is due to the fact that the bodys immune system attacks beta cells in the pancreas, which control insulin production. Professor Melton, along with a whole host of … Continue reading

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Firm acquires rights to spider-venom drug

Posted: Published on October 10th, 2014

Akashi Therapeutics Inc., a clinical-stage biopharmaceutical company, has acquired the rights to a drug that UB scientists have begun developing for Duchenne muscular dystrophy, a common, fatal genetic disease affecting young boys. The potential therapy is called AT-300. It is a modified form of a small protein UB researchers first discovered in the venom of the Chilean rose tarantula. AT-300 promises to slow the muscle deterioration that characterizes muscular dystrophy. In patients with dystrophy, genetic mutations weaken the membrane of muscle cells, enabling large amounts of calcium to infiltrate the cells. This sets off a chain reaction that leads to muscle degeneration. AT-300 has been shown, in laboratory studies, to stop the dangerous calcium influx by keeping pores called mechanosensitive ion channels shut when the muscle cells are stretched, says UB scientist Frederick Sachs, who led the research. The protein also holds promise for preventing cardiac failure, one of the most common causes of death in dystrophic boys, he adds. Akashi Therapeutics will fund further development of AT-300. The company is licensing the rights to the protein from Tonus Therapeutics, a UB spinoff Sachs co-founded with colleagues and a Western New York stockbroker whose grandson has Duchenne muscular dystrophy. About … Continue reading

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Epilepsy Foundation and George Washington University Epilepsy Center Partner to Webcast Grand Rounds Series on …

Posted: Published on October 10th, 2014

Contact Information Available for logged-in reporters only Newswise WASHINGTON (Oct. 9, 2014) Epilepsy.com, the largest website worldwide dedicated to epilepsy and seizures, will begin hosting Epilepsy Grand Rounds, a monthly seminar series by the George Washington University (GW) Epilepsy Center. The series, which began in January 2013, covers a wide variety of epilepsy-related topics, presented by renowned experts in the field. Thanks to our partnership with Epilepsy.com, this series will now be visible to hundreds of thousands of physicians, health care providers, and lay persons from all over the world, said Mohamad Koubeissi, M.D., director of the GW Epilepsy Center and associate professor of neurology at the GW School of Medicine and Health Sciences. With this exposure, we will have greater opportunity to educate and improve knowledge, competence, and clinical performance of larger numbers of attendees. With more than 1.3 million page views per month and over 600,000 unique visitors per month, the Epilepsy Foundations Epilepsy.com is the premier destination for people living with epilepsy, their caregivers, and experts in seizure treatment, care, and research. The webinar series will be hosted within epilepsy.com/professionals, a section of the site that provides a forum for strong and innovative voices in the field. … Continue reading

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6-year-old SC girl gets cannabis oil treatment

Posted: Published on October 10th, 2014

By - Associated Press - Friday, October 10, 2014 HILTON HEAD ISLAND, S.C. (AP) - The 6-year-old girl whose family helped get a law passed in South Carolina allowing people suffering from severe epilepsy to use oil derived from marijuana to control their seizures has received her first dose. Jill Swing said she saw instant improvement last week after her daughter took cannabidiol, which is also known as CBD oil. Before the treatment, Swing says her daughter was having more than 100 seizures during a 45-minute therapy session. After receiving CBD oil, she had 19 seizures during a similar session. Also, she wont quit talking, Swing told The Island Packet of Hilton Head (http://bit.ly/Zih5Zu). Its been delightful. She was nonverbal, but shes saying more words now. Shes a chatterbox, Swing said. Swing said she will gradually begin increasing her daughters dose as long as she continues to respond well to it. In November, the family will fly to Massachusetts to participate in a study that will give them better access to CBD oil. One of the lawmakers that helped get the bill passed that allowed Mary Louise to get her treatment said he will file a bill next session to … Continue reading

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Stroke Treatment Paralysis Treatment in India | Satisfied Patient – Video

Posted: Published on October 10th, 2014

Stroke Treatment Paralysis Treatment in India | Satisfied Patient Treats patients with tested Ayurvedic Medicines which do not produce any side effects Dr.Dassan's Ayurvedic Herbal Centre does not believe in hit and trial m... By: Dr Dassan's Ayurvedic Herbal Formulations … Continue reading

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Intracranial stents: More strokes than with drug treatment alone

Posted: Published on October 10th, 2014

The risk of having another stroke is higher if patients, after dilation of their blood vessels in the brain, not only receive clot-inhibiting drugs, but also have small tubes called stents inserted. However, studies have provided no hint of a benefit from stenting, which is also referred to with the abbreviation "PTAS." This is the conclusion reached in the rapid report of the German Institute for Quality and Efficiency in Health Care (IQWiG), as published on 9 October 2014. Stents are supposed to prevent restenosis Blood vessels in the brain that are narrowed or blocked can cause stroke. If patients have already had a stroke or temporary ischaemia (transient ischaemic attack, TIA), there is a high risk that this occurs again. These patients therefore receive drugs that prevent blood clotting. Another option is to additionally widen the narrowed vessels. Nowadays this is often done using a small balloon in a procedure known as percutaneous transluminal angioplasty (PTA). But even after PTA and simultaneous blood-thinning medication, vessels often remain narrow (stenosis) or new narrowing occurs (restenosis). The treatment has therefore been expanded to include stenting (percutaneous transluminal angioplasty and stenting, PTAS): Small wire mesh tubes are inserted to support the widened … Continue reading

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