PUBLIC RELEASE DATE: 9-Oct-2014 Contact: Kathryn Ryan kryan@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News @LiebertOnline New Rochelle, NY, October 9, 2014Laser Solid Forming (LSF) is an innovative method for direct fabrication of metallic components in additive manufacturing. Renowned researchers Weidong Huang and Lin Xin, from China's Northwestern Polytechnical University, Shaanxi, describe their progress and applications with LSF technology and the excellent mechanical properties of the metallic parts produced in a Review article in 3D Printing and Additive Manufacturing, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the 3D Printing and Additive Manufacturing website until November 9, 2014. In the article "Research Progress in Laser Solid Forming of High Performance Metallic Components at the State Key Laboratory of Solidification Processing of China," the authors review research advances toward the goal of developing LSFan additive manufacturing technique that uses laser cladding with synchronously feeding metal powdersfor obtaining fully dense metal parts with mechanical properties similar to those produced by casting or forging. "Additive manufacturing technologies have a global reach that is impacting the manufacturing landscape worldwide, and it is critical that both technology developers and users across the planet keep abreast of each other's … Continue reading →

PUBLIC RELEASE DATE: 9-Oct-2014 Contact: Kathryn Ryan kryan@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News @LiebertOnline New Rochelle, NY, October 9, 2014Excessive and often lethal blood levels of bilirubin can result from mutations in a single gene that are the cause of the metabolic disease known as Crigler-Najjar syndrome type 1 (CNS1). A new gene therapy approach to correcting this metabolic error achieved significant, long-lasting reductions in bilirubin levels in a mouse model of CNS1 and is described in an Open Access article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Human Gene Therapy website at http://online.liebertpub.com/doi/full/10.1089/hum.2013.233. In "Life-Long Correction of Hyperbilirubinemia with a Neonatal Liver-Specific AAV-Mediated Gene Transfer in a Lethal Mouse Model of CriglerNajjar Syndrome," Giulia Bortolussi and coauthors from the International Centre for Genetic Engineering and Biotechnology; Centro Studi Fegato, Fondazione Italiana Fegato; and University of Trieste (Trieste, Italy) and Charles University (Prague, Czech Republic), present details of the adeno-associated virus (AAV)-mediated gene therapy approach they used to correct the metabolic disorder that causes hyperbilirubinemia in CNS1. The researchers reported 70-80% reductions in plasma bilirubin levels early on among treated animals, with about 50% reductions maintained … Continue reading →