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DNA Sequencing Kit generates ChIP-seq libraries for NGS.

Posted: Published on September 29th, 2014

September 29, 2014 - In DNA SMART ChIP-Seq Kit, adaptation of template switching technology is used to add Illumina-specific adapters directly to DNA. This produces ChIP-seq libraries without additional ligation or clean-up steps. Kit generates libraries with good complexity and low redundancy from low-input samples (100 pg-10 ng) using simple protocol. SMART (Switching Mechanism at 5' End of RNA Template) technology, when applied to RNA, allows for full-length cDNA synthesis with direct addition of PCR adapter. Clontech Laboratories, Inc. 1020 E. Meadow Circle Palo Alto, CA, 94303 USA Press release date: September 22, 2014 MOUNTAIN VIEW, Calif., -- Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the launch of the DNA SMART ChIP-Seq Kit. This kit adapts Clontech's patented SMART technology in an innovative manner for use with low-input samples, including both dsDNA and ssDNA templates, to generate ChIP-seq libraries for NGS. SMART (Switching Mechanism at 5' End of RNA Template) technology, when applied to RNA, allows for full-length cDNA synthesis with direct addition of a PCR adaptor. In the DNA SMART ChIP-Seq Kit, a novel, patent-pending adaptation of template switching technology is used to add Illumina-specific adaptors directly to DNA. This produces ChIP-seq libraries without … Continue reading →

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Viral infection might just be a phase… transition

Posted: Published on September 29th, 2014

PUBLIC RELEASE DATE: 29-Sep-2014 Contact: Jocelyn Duffy jhduffy@andrew.cmu.edu 412-268-9982 Carnegie Mellon University @CMUScience PITTSBURGHMany double-stranded DNA viruses infect cells by ejecting their genetic information into a host cell. But how does the usually rigid DNA packaged inside a virus' shell flow from the virus to the cell? In two separate studies, Carnegie Mellon University biophysicist Alex Evilevitch has shown that in viruses that infect both bacteria and humans, a phase transition at the temperature of infection allows the DNA to change from a rigid crystalline structure into a fluid-like structure that facilitates infection. The findings, published in Nature Chemical Biology and the Proceedings of the National Academy of Sciences (PNAS), provide a promising new target for antiviral therapies. Most antiviral drugs work by deactivating viral proteins, but viruses often evolve and become drug resistant. Evilevitch believes that researchers now have a possible new way to prevent infection blocking the phase transition. Such a therapy could be generalizable across all types of Herpes viruses, and wouldn't be prone to developing resistance. "The exciting part of this is that the physical properties of packaged DNA play a very important role in the spread of a viral infection, and those properties are universal," … Continue reading →

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Water in space and the Earth – Video

Posted: Published on September 29th, 2014

Water in space and the Earth An animation from space, frozen water rocks and the emergence of Earth. This animation was used as part of the life of water show created for the Royal Society of Chemistry. The work was commission... By: Royal Society of Chemistry … Continue reading →

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The water cycle supporting life on Earth – Video

Posted: Published on September 29th, 2014

The water cycle supporting life on Earth An animation for the transpiration of water to support life. The water cycle before your very eyes. This animation was used as part of the life of water show created for the Royal Society of... By: Royal Society of Chemistry … Continue reading →

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IGCSE Chemistry Periodic Table Lesson 2: General Properties of Elements – Video

Posted: Published on September 29th, 2014

IGCSE Chemistry Periodic Table Lesson 2: General Properties of Elements Core LO: Describe the Periodic Table as a method of classifying elements and its use to predict properties of elements. SC: Remember that metals have delocalised electrons that give... By: Ben Koh … Continue reading →

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Organic Chemistry MV – Video

Posted: Published on September 29th, 2014

Organic Chemistry MV By: Manunya Kanchanapiboon … Continue reading →

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IGCSE Chemistry Periodic Table Lesson 5: Group 1 Trends – Video

Posted: Published on September 29th, 2014

IGCSE Chemistry Periodic Table Lesson 5: Group 1 Trends Core LO: Describe lithium, sodium and potassium in Group I as a collection of relatively soft metals showing a trend in melting point, density and reaction with water; Predict the propertie... By: Ben Koh … Continue reading →

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Golddigger – Kanye West PARODY – 5A Chemistry Safety Video for OJ – Video

Posted: Published on September 29th, 2014

Golddigger - Kanye West PARODY - 5A Chemistry Safety Video for OJ Group Members: Victor Espinoza - Rowe Aaron Garza - Memorial Kalvin Martinez - Memorial Vallery Valle - Rowe LYRICS: [Intro] He teaches safety, so I don't bleed Yeah he's a chem'stry... By: Kalvin Martinez … Continue reading →

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Chemistry Teacher, China

Posted: Published on September 29th, 2014

Opened in September 2012, Malvern College Qingdao currently has 300+ students between Y9-12. The College brings the best of British boarding school traditions to China, providing Chinese and international students with a holistic education, preparing them for university education overseas. Qingdao is a major seaport in Shandong Province looking out over the Yellow Sea, an hour's flight time from Beijing, Shanghai and Seoul. It has a rich heritage and a temperate climate. It is one of the most affluent and fastest growing cities in China and in 2009 the city was deemed the most liveable in China. Our purpose-built campus set is on the edge of the city with lovely rural views and is 20 minutes away from Qingdao International Airport. The core management team of Malvern College Qingdao consists of graduates from Harvard and Oxford Universities, who have considerable experience of working in leading multi-national organisations. Inheriting the ethos of Malvern College while adapting to the needs of students in China, Malvern College Qingdao strives to provide a forward-looking educational approach suitable for developing leaders for the 21st century. With this vision, we offer high-quality, personalised, holistic and international education at post-15 level. Students join from 14 or above, … Continue reading →

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Matter of chemistry

Posted: Published on September 29th, 2014

Melissa Healy Tuesday, September 30, 2014 Using mice that were stressed to the point where depression would be a predictable response, researchers at Sweden's Karolinska Institute in Stockholm uncovered a series of biochemical events that begins with exercise and ends with mice that are resilient to stress. Their findings, published last week in the journal Cell, not only illuminate the link between chronic stress and depression; they help explain how a known anti-depressive agent - in this case exercise - works to prevent or mitigate the debilitating mental condition. That is more than can be said for many antidepressant medications, which clearly help many with depression, but whose mechanism of action is not all that well understood. The findings also point the way to a novel way to ward off depression. Antidepressant medications seem to rely largely on changing brain chemistry, and they require the use of molecules that cross the barrier that protects the brain against most blood- borne toxins. But the Swedish researchers found that exercise's therapeutic effects begin in the muscles, and alter brain chemistry only indirectly. Finding a way to mimic exercise's antidepressant effect could also be of "great therapeutic value" to patients who are not … Continue reading →

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