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013 Ninjas vs Superbugs Adventures in Nanomedicine – Video

Posted: Published on September 11th, 2014

013 Ninjas vs Superbugs Adventures in Nanomedicine By: Sophia Wight … Continue reading

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Fantastic voyage in nanomedicine takes us into realm of science fiction

Posted: Published on September 11th, 2014

In 1966, scientists made a huge breakthrough in nanomedicine. They found they could miniaturise a submarine and its crew and inject it into a patients bloodstream. The sub then wound its way through the patients body till it reached the brain, where the crew could then destroy a blood clot using laser guns. Of course, this was pure science fiction. It was the plot of the movie Fantastic Voyage, a phantasmagorical thriller in which the intrepid crew of the Proteus had just one hour to save the life of a top scientist, while avoiding such dangers as voracious white blood cells, lymph nodes and enemy spies. As a kid, I was enthralled by the film: secret agents, giant man-eating antibodies, and Raquel Welch as a sexy scientist it was a boys own fantasy. In real life, were a long way from shrinking people and sending them inside someones body to carry out surgical procedures. But we are able to use nanoparticles as intravenous couriers to deliver drugs to specific parts of the body, or to sneak tiny Trojan horses into cancerous cells to destroy them from the inside. In Ireland, pioneering research into nanomed is being done at Crann, the … Continue reading

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Combining antibodies, iron nanoparticles and magnets steers stem cells to injured organs

Posted: Published on September 11th, 2014

PUBLIC RELEASE DATE: 10-Sep-2014 Contact: Sally Stewart sally.stewart@cshs.org 310-248-6566 Cedars-Sinai Medical Center LOS ANGELES Researchers at the Cedars-Sinai Heart Institute infused antibody-studded iron nanoparticles into the bloodstream to treat heart attack damage. The combined nanoparticle enabled precise localization of the body's own stem cells to the injured heart muscle. The study, which focused on laboratory rats, was published today in the online peer reviewed journal Nature Communications. The study addresses a central challenge in stem cell therapeutics: how to achieve targeted interactions between stem cells and injured cells. Although stem cells can be a potent weapon in the fight against certain diseases, simply infusing a patient with stem cells is no guarantee the stem cells will be able to travel to the injured area and work collaboratively with the cells already there. "Infusing stem cells into arteries in order to regenerate injured heart muscle can be inefficient," said Eduardo Marbn, MD, PhD, director of the Cedars-Sinai Heart Institute, who led the research team. "Because the heart is continuously pumping, the stem cells can be pushed out of the heart chamber before they even get a chance to begin to heal the injury." In an attempt to target healing stem cells … Continue reading

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Inherited immunodeficiency:genetics and therapy Dr Siobhan Burns – Video

Posted: Published on September 11th, 2014

Inherited immunodeficiency:genetics and therapy Dr Siobhan Burns http://www.ucl.ac.uk/immunity-transplantation. By: UCL Institute of Immunity and Transplantation … Continue reading

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Human Development: Genetics 1 – Video

Posted: Published on September 11th, 2014

Human Development: Genetics 1 ETSU Online Programs - http://www.etsu.edu/online Module 2- Human Development: Genetics MOD 02 EP 01. By: East Tennessee State University … Continue reading

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Oxford Genetics Introduction Film – Video

Posted: Published on September 11th, 2014

Oxford Genetics Introduction Film Introduction to Oxford Genetics DNA Products and Services. By: Ryan Cawood … Continue reading

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Changing Your Genetics! – Video

Posted: Published on September 11th, 2014

Changing Your Genetics! Online And In Person Training with Bios3: bios3training@gmail.com 5% nutrition (Rich Piana) http://5percentnutrition.com/ GASP and BETTER BODIES CLOTHING https://elite1fitgear.refersion.com/c/1... By: bios3training … Continue reading

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Seattle Genetics, Genmab In New Antibody-Drug Conjugate Collaboration

Posted: Published on September 11th, 2014

By RTT News, September 10, 2014, 12:14:00 PM EDT (RTTNews.com) - Seattle Genetics Inc ( SGEN ) and Genmab A/S (GNMSF.PK) on Wednesday entered into an additional antibody-drug conjugate collaboration. Under the new agreement, Genmab will pay an upfront fee of $11 million for exclusive rights to utilize Seattle Genetics' auristatin-based Antibody-Drug Conjugate (ADC) technology with Genmab's HuMax-AXL, an antibody targeting AXL which is expressed on multiple types of solid cancers. Seattle Genetics is also entitled to receive more than $200 million in potential milestone payments and mid-to-high single digit royalties on worldwide net sales of any resulting products. In addition, prior to Genmab's initiation of a Phase III study for any resulting products, Seattle Genetics has the right to exercise an option to increase the royalties to double digits in exchange for a reduction of the milestone payments owed by Genmab. Irrespective of any exercise of option, Genmab remains in full control of development and commercialization. Seattle Genetics and Genmab entered into an ADC collaboration for HuMax-TF-ADC in September 2010. HuMax-TF-ADC, targeting the Tissue Factor antigen, is in a Phase I trial for solid tumors. Seattle Genetics has the right to exercise a co-development option to share all future … Continue reading

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Seattle Genetics And Genmab Enter Into Collaboration

Posted: Published on September 11th, 2014

Seattle Genetics, Inc. today announced that the companies have entered into an additional antibody-drug conjugate collaboration. Under the new agreement, Genmab will pay an upfront fee of $11 million for exclusive rights to utilize Seattle Genetics auristatin-based ADC technology with Genmabs HuMax-AXL, an antibody targeting AXL which is expressed on multiple types of solid cancers. Seattle Genetics is also entitled to receive more than $200 million in potential milestone payments and mid-to-high single digit royalties on worldwide net sales of any resulting products. In addition, prior to Genmabs initiation of a Phase III study for any resulting products, Seattle Genetics has the right to exercise an option to increase the royalties to double digits in exchange for a reduction of the milestone payments owed by Genmab. Irrespective of any exercise of option, Genmab remains in full control of development and commercialization. This collaboration with Genmab further extends the reach of our industry-leading ADC technology for use with novel oncology targets, while providing us with a compelling financial value proposition as the program advances, said Natasha Hernday, Vice President, Corporate Development at Seattle Genetics. Genmabs impressive track record in the development of antibody-based therapies for the treatment of cancer, including an … Continue reading

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Myriad Genetics Posts Encouraging myPath Melanoma Data – Analyst Blog

Posted: Published on September 11th, 2014

Myriad Genetics, Inc. ( MYGN ) reported encouraging results from a pivotal clinical utility study of its myPath Melanoma test at the 2014 College of American Pathologists (CAP) annual meeting in Chicago. myPath Melanoma is a clinically validated gene expression molecular test that has been designed to differentiate malignant melanoma from benign skin lesions, with more than 90% accuracy. This study evaluated 687 pigmented skin lesions submitted by 42 dermatopathologists who were then asked to document their diagnosis, level of confidence, further testing and treatment recommendations, both pre- and post-receipt of the myPath test results. The results showed that 35% of these dermatologists revised their treatment recommendation after receiving the myPath Melanoma test score. Moreover, the test score led to a 76% reduction in "indeterminate" diagnoses. According to Myriad, these data support the integration of myPath Melanoma into clinical practice for improvement of the diagnosis of melanoma, thereby enhancing the scope of patient care. With certain melanomas imitating benign skin lesions, it becomes quite difficult for clinicians to diagnose the former in patients accurately. In such situations, Myriad myPath Melanoma comes of help as it has the ability to discriminate malignant melanoma from benign skin lesions. Management at Myriad strongly … Continue reading

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