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Longitudinal study explores white matter damage, cognition after traumatic axonal injury

Posted: Published on September 3rd, 2014

PUBLIC RELEASE DATE: 3-Sep-2014 Contact: Shelly Kirkland shelly.kirkland@utdallas.edu 972-883-3221 Center for BrainHealth Traumatic Axonal Injury is a form of traumatic brain injury that can have detrimental effects on the integrity of the brain's white matter and lead to cognitive impairments. A new study from the Center for BrainHealth at The University of Texas at Dallas investigated white matter damage in the acute and chronic stages of a traumatic axonal injury in an effort to better understand what long-term damage may result. The study, published online July 21 in the Journal of Neurotrauma, looked at 13 patients ages 16 to 60 with mild to severe brain injuries from the intensive care unit at a Level I trauma center. This group was matched to a cohort of 10 healthy individuals resembling the age, gender, and ethnicity of the patients. White matter integrity was measured using diffusion tensor imaging (DTI) in the acute stage of injury, at day one, and again at the chronic stage, seven months post-injury. In addition, neuropsychological assessments measured cognitive performance including processing speed, attention, learning and memory at both stages after injury. "We intended to determine whether DTI could not only identify early compromise to white matter, but … Continue reading →

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Children's Researchers Focus on Biomarkers to Treat Neonatal Brain Injury

Posted: Published on September 3rd, 2014

Washington, DC (PRWEB) September 03, 2014 To improve treatments of babies with perinatal hypoxic ischemic encephalopathy (HIE), a major cause of brain injury in newborns, Childrens National Health System researchers have focused on a physiological biomarker, Heart Rate Variability (HRV), which can help better predict neurological outcomes, including whether different cooling patterns can improve care. Their study was published in June in the Journal of Perinatology. A key finding is the recommendation to tailor therapies to an individuals biological profile and ongoing response to treatment and evaluate whether heart rate variability measures can be predictive of a childs neurological outcome. The study showed that biomarkers can change at different times, and the cooling process may need to change as well. Heart Rate Variability (HRV) is most impacted in brain-injured patients during two key periods, at 24 hours after birth and after 80 hours. Cooling procedures have been the hallmark of treating babies with HIE, but 40 percent of children treated this way continue to have moderate-to-serve disabilities or die. HIE is a major cause of long-term neurological complications, from mild to severe, including mental retardation and cerebral palsy. The studys authors included members of Childrens National staff representing a joint … Continue reading →

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Breakthrough hope for MS treatment as scientists discover how to 'switch off' autoimmune diseases

Posted: Published on September 3rd, 2014

Team at Bristol University have described their work as a 'breakthrough' Discovered a way to stop cells from attacking healthy body tissue Conditions which could benefit include MS and type 1 diabetes By Lizzie Parry for MailOnline Published: 05:42 EST, 3 September 2014 | Updated: 08:10 EST, 3 September 2014 2k shares 26 View comments Scientists believe they have discovered how to 'switch off' autoimmune diseases, prompting hope the breakthrough could pave the way for a new treatment for multiple sclerosis. Researchers at the University of Bristol, who describe the work as an 'important breakthrough', say it could improve the lives of millions around the world. The study reveals how to stop cells from attacking healthy body tissue. The team discovered how cells convert from being aggressive to protecting against disease, rather than the body's immune system destroying its own tissue by mistake. Read more from the original source: Breakthrough hope for MS treatment as scientists discover how to 'switch off' autoimmune diseases … Continue reading →

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Breakthrough Hope For MS: Could There Be A Way To 'Switch Off' The Disease?

Posted: Published on September 3rd, 2014

MS sufferers could soon be able to "switch off" their illness following a potential medical breakthrough from researchers at the University of Bristol - a result which could improve the lives of 2.5 million people worldwide. The findings could affect a range of autoimmune diseases such as multiple sclerosis (MS), type 1 diabetes, Graves' disease and systemic lupus erythematosus. In their research, published today in Nature Communications, the team reveal how to stop cells from attacking healthy body tissue. The team discovered how cells convert from being aggressive to protecting against disease, rather than the body's immune system destroying its own tissue by mistake. It is hoped the insight will lead to the widespread use of antigen-specific immunotherapy as treatment for many autoimmune disorders. Professor David Wraith, of the university's School of Cellular and Molecular Medicine, led the "exciting" research - which was funded by the Wellcome Trust. "Insight into the molecular basis of antigen-specific immunotherapy opens up exciting new opportunities to enhance the selectivity of the approach while providing valuable markers with which to measure effective treatment," Professor Wraith said. "These findings have important implications for the many patients suffering from autoimmune conditions that are currently difficult to treat." … Continue reading →

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Event Gathers World-Renowned Researchers and Community Leaders to Find a Cure for Rare Disease, Friedreichs Ataxia

Posted: Published on September 3rd, 2014

Tampa, Fla. (PRWEB) September 02, 2014 Scientists, physicians, patients, families, and community leaders will join together in Tampa Bay from September 4-6 for the Friedreichs Ataxia Research Alliances (FARA) sixth annual Scientific Symposium and FARA Energy Ball Gala. The Energy Ball benefits FARA and the USF Ataxia Research Center in their pursuit of treatment and cure for the 15,000 people worldwide affected by the progressive neuromuscular disease Friedreichs ataxia (FA). The annual gathering provides an excellent chance for scientists to discuss research developments, for patients and their families to be updated on advancements, and for those who care about FA to lend a supportive hand, says Ronald Bartek, President of FARA. FA is the most common of the inherited ataxias. Over the course of the disease, individuals develop balance issues often leading to full-time wheelchair use, impaired speech, hearing and vision loss, and ultimately, a shortened lifespan due to heart complications. Currently, there is no known treatment or cure for FA. International leaders in FA research and the FA community will attend the Understanding Energy for a Cure Scientific Symposium on September 4 to discuss advancements in FA therapeutic approaches. Updates of ongoing drug discovery efforts, clinical trials, along with … Continue reading →

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Genetic 'hotspot' linked to endometrial cancer aggressiveness

Posted: Published on September 3rd, 2014

PUBLIC RELEASE DATE: 3-Sep-2014 Contact: Ron Gilmore rlgilmore1@mdanderson.org 713-745-1898 University of Texas M. D. Anderson Cancer Center Parents of twins often tell them apart through subtle differences such as facial expression, moles, voice tone and gait. Similarly, physicians treating women with endometrial cancer must be able to distinguish between different versions of this disease form that, on the surface, appear the same. With endometrial cancer, the most common gynecological cancer in the western world and the fourth most prevalent in the U.S., it can literally be a matter of life and death. Mortality rates from this cancer have nearly tripled in the last 25 years and are thought to be attributed to the rising incidence of obesity. Scientists at The University of Texas MD Anderson Cancer Center in Houston have identified genetic mutations in endometrioid endometrial carcinoma (EEC), the most common form of this cancer of the uterine lining. The mutations revealed a more lethal version of an EEC subtype previously thought to respond well to treatment. It's possible that by identifying these patients early on, oncologists can try more aggressive treatment approaches to increase the likelihood for a positive outcome. "EEC is categorized into subtypes that help determine risk … Continue reading →

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Bengtson Center Expands Body Contouring and Aesthetic Surgery Practice With New Plastic Surgeon

Posted: Published on September 2nd, 2014

Grand Rapids, Mich. (PRWEB) September 02, 2014 The Bengtson Center for Aesthetics and Plastic Surgery, West Michigans leading plastic surgery and skin and laser treatment center, today announced Ryan Mitchell, MD, FRCSC will join the center to lead its growing body contouring practice. Plastic surgery is often required following dramatic or rapid weight loss, frequently the result of dieting alone or a bariatric/weight loss surgical procedure. A wide variety of post-bariatric or body contouring surgical procedures such as tummy tuck and liposuction remove excess sagging skin that leaves many patients self-conscious. Post weight loss surgery helps to improve and the shape of the underlying support tissue of a persons body. The result is a more natural appearance with smoother contours of the abdomen, arms, legs and buttocks area. Dr. Mitchell is an up and coming leader in the research and study of Body Contouring and reconstructive surgery, recently completed a prestigious Fellowship at the University of Pittsburgh Medical Center, where he specialized in procedures to treat the after-effects of post-bariatric surgery under the auspices of Dr. Peter Rubin. The majority of his patients have lost over one hundred pounds during the course of their surgery, and were left with a … Continue reading →

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Reneuron on track for clinical milestones as studies get underway

Posted: Published on September 2nd, 2014

ReNeuron Group Quote more Price: 3.62 Chg: -0.19 Chg %: -4.87% Date: 16:38 Stem cell therapy group Reneuron said it remains on track with the first patients having been dosed in two its clinical trials. The phase II trial for the ReN001 cell therapy candidate for stroke disability and the phase I trail for ReN009 cell therapy candidate for critical limb ischaemia have both begun. The ReN001 trial is on course to have generated six month follow-up data by the end of 2015, while ReN009 study should give results in the first half of next year. Chief executive officer (CEO) Michael Hunt said that Reneuron's core therapeutic programmes remain on track towards "further important clinical milestones" over the next 18 months. "In particular, the commencement of dosing of patients in two new clinical trials, in stroke and limb ischaemia, marks another significant step in Reneuron's evolution into a fully-fledged clinical development business and a leading player in the increasingly exciting field of cell therapy and regenerative medicine," Hunt said. View post: Reneuron on track for clinical milestones as studies get underway … Continue reading →

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Richfeel: Have a great hair day – Video

Posted: Published on September 2nd, 2014

Richfeel: Have a great hair day Dr. Apoorva Shah Dr. Sonal Shah, India's leading trichologists and founder of Richfeel Hair and Scalp Clinic, talk about Hair fall Hair prevention. Also, explaining about plant stem-cell... By: Richfeel Trichology … Continue reading →

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Hitguj Dr Anant Bagul On Stem Cell Treatment And Small Children Brain Development – Video

Posted: Published on September 2nd, 2014

Hitguj Dr Anant Bagul On Stem Cell Treatment And Small Children Brain Development For more info log on to http://www.24taas.com Like us on https://www.facebook.com/Zee24Taas Follow us on https://twitter.com/zee24taasnews. By: Zee24Taas … Continue reading →

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