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New Research Method Opens Door to Therapy with Human Muscle Stem Cells Promising Method Developed

Posted: Published on August 28th, 2014

27.08.2014 - (idw) Max-Delbrck-Centrum fr Molekulare Medizin (MDC) Berlin-Buch Stem cells are essential for the repair of muscle damage, but all attempts to manipulate human muscle stem cells for therapy have thus far failed. Now Dr. Andreas Marg and Prof. Simone Spuler of the Experimental and Clinical Research Center (ECRC), a joint cooperation between the Max Delbrck Center (MDC) and the Charit, have shown how this might work. They developed a method in which they did not isolate the muscle stem cells, but rather cultivated, proliferated and transplanted them along with their muscle fibers. Using this method in mice, they were able to successfully regenerate muscle tissue. Thus they have opened the door for the use of muscle stem cells to treat muscle diseases.* "Muscle stem cells, which we also refer to as satellite cells, can awaken in their stem cell niche after decades of quiescence and can then repair damaged muscle tissue," Professor Spuler explained. At the ECRC in Berlin-Buch, the neurologist heads the University Outpatient Clinic for Muscle Disorders and the Department of Muscle Sciences. She and her team are exploring the causes of muscle diseases. Evidence shows that satellite cells are active in people with severe muscle … Continue reading →

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The Sims 3 | Perfect Genetics Challenge Part 22: Like Father, Like Son – Video

Posted: Published on August 27th, 2014

The Sims 3 | Perfect Genetics Challenge Part 22: Like Father, Like Son In this part, Cassandra finds out shes pregnant and we age up Caleb. The Sims 3 Perfect Genetics Playlist: https://www.youtube.com/playlist?list=PL0BV_YFL-2I77acu9TBO5aor9CgMW97mo Links!... By: simplyapril … Continue reading →

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Israelites – Genetics, Color, ESAU and Leprosy – Video

Posted: Published on August 27th, 2014

Israelites - Genetics, Color, ESAU and Leprosy An understanding and physical example of Esau, Leprosy and recessive genes. By: Truenation12 … Continue reading →

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Study finds genetics play role in hangovers

Posted: Published on August 27th, 2014

By Jillian Rose Lim July 24, 2014: Olalla Gomez, 22, a final-year student of English philology who is also on on the first day of her probation period before getting a contract as temporary waiter, holds a mug of beer in the "Los Capeas" restaurant in downtown Ronda, near Malaga, southern Spain.Reuters Some people get hangovers after a night of drinking, while others don't, and the reason may be in their genes, a new study of twins in Australia suggests. Researchers looked for links between the study participants' genetic makeups and the number of hangovers the individuals reported experiencing in the past year. The results showed that genetic factors accounted for 45 percent of the difference in hangover frequency in women and 40 percent in men. In other words, genetics accounts for nearly half of the reason why one person experiences a hangover and another person doesn't, after drinking the same amount of alcohol, the study said. The other half probably comes from outside influences unrelated to DNA, such as how quickly a person drinks, whether they eat while they drink and their tolerance for alcohol. The researchers also found that the people who had the gene variants involved in … Continue reading →

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DID ALIENS CREATE HUMANS? (EXTRATERRESTRIAL GENETIC ENGINEERING DOCUMENTARY) – Video

Posted: Published on August 27th, 2014

DID ALIENS CREATE HUMANS? (EXTRATERRESTRIAL GENETIC ENGINEERING DOCUMENTARY) DID ALIENS CREATE HUMANS? (EXTRATERRESTRIAL GENETIC ENGINEERING DOCUMENTARY) Evidence clearly indicates that modern man is not the result of a linear evoluti... By: ParaNormality … Continue reading →

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Attacking a Rare Disease at its Source With Gene Therapy

Posted: Published on August 27th, 2014

Contact Information Available for logged-in reporters only Newswise PHILADELPHIA Treating the rare disease MPS I is a challenge. MPS I, caused by the deficiency of a key enzyme called IDUA, eventually leads to the abnormal accumulation of certain molecules and cell death. The two main treatments for MPS I are bone marrow transplantation and intravenous enzyme replacement therapy, but these are only marginally effective or clinically impractical, especially when the disease strikes the central nervous system (CNS). Using an animal model, a team from the Perelman School of Medicine at the University of Pennsylvania has proven the efficacy of a more elegant way to restore IDUA levels in the body through direct gene transfer. Their work was published this week online in Molecular Therapy. The study provides a strong proof-of-principle for the efficacy and practicality of intrathecal delivery of gene therapy for MPS patients, said lead author James M. Wilson, MD, PhD, professor of Pathology and Laboratory Medicine and director of the Penn Gene Therapy Program. This first demonstration will pave the way for gene therapies to be translated into the clinic for lysosomal storage diseases. This family of diseases comprises about 50 rare inherited disorders marked by defects in … Continue reading →

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Embryology – Gastrointestinal Tract Development Part 1 ( High yield ) – Video

Posted: Published on August 27th, 2014

Embryology - Gastrointestinal Tract Development Part 1 ( High yield ) These videos are designed for medical students studying for the USMLE step 1 . I took step 1 when i was in 5th grade , my step 1 score : 241 , i did these vi... By: First Aid Review UW and Nbmes notes for Usmle Step 1 … Continue reading →

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DNA Smart Prepaid – tydellinen prepaid-liittym lypuhelimeen – Video

Posted: Published on August 27th, 2014

DNA Smart Prepaid - tydellinen prepaid-liittym lypuhelimeen Tydellinen liittym lypuhelimeen - DNA Smart Prepaid. Puhut, viestittelet ja surffaat 4G-nopeudella kiinten pivhintaan alk. 0,69 /vrk. Hae omasi R-kioskilta! By: DNA … Continue reading →

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Monster DNA made with Swarovski Elements Purple Velvet Tazanite – Video

Posted: Published on August 27th, 2014

Monster DNA made with Swarovski Elements Purple Velvet Tazanite Monster's on-ear headphones are a cutting-edge fusion of high design and excellent audio playback that will tease exceptional results from every track. The soft ear cushions and snug fit... By: Crystal Rocked … Continue reading →

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DNA: The plight of village women who walk for miles to fetch water – Video

Posted: Published on August 27th, 2014

DNA: The plight of village women who walk for miles to fetch water It's a never ending job for Indian women who live in villages. Water sources are often far from the village and women walk for hours to fetch water daily. By: Zee News … Continue reading →

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