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Researchers investigate origins of MS to target treatment

Posted: Published on August 25th, 2014

Published August 25, 2014 Researchers at Hofstra Northshore-LIJ School of Medicine have found the origins of the cell believed to cause multiple sclerosis (MS). In a study published in Science Translational Medicine, researchers investigated B cells, a type of immune cell believed to be responsible for attacking brain tissue. In patients with MS, the immune system attacks the protective myelin covering the nerves. This damage disrupts communication between the brain and the rest of the body ultimately leading to irreversible nerve deterioration. B cells mutate as they migrate through the bodys tissues, which allowed researchers to determine the starting point. Our objective was to determine the origin and map the course of these cell abnormalities in the hope of targeting them for further investigations in MS treatment, study author Joel N.H. Stern, an assistant professor of science education at the School of Medicine said in a press release. Currently available MS treatments manage symptoms by using drugs that diffuse in the brain. Targeted treatments can be difficult and ineffective because of the brains protective barrier. The study of B cells may improve treatment efficacy. Since B cells travel in and out of the brain of MS patients repeatedly, our results … Continue reading

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'We had faith experts would care for her'

Posted: Published on August 25th, 2014

Alana Goldsmith's mother, Judy, and sister Simone, at their home in Cammeray. Photo: Getty Images/Ben Rushton An eating disorder clinic made several mistakes in its treatment of a woman who escaped and killed herself - but the failures were not the ultimate cause of her death, a coroner has found. NSW Coroner Mark Douglass found Alana Goldsmith, 23, most likely killed herself as a result of her nine-year struggle with anorexia nervosa. "It is clear the mental illness/condition anorexia nervosa played a foundational role in Alana Goldsmith's decision and ultimately her tragic death," Mr Douglass said in findings handed down on Monday. Alana Goldsmith died after escaping from an eating disorders clinic in Ashfield. Photo: Supplied The former Barker College student died at Summer Hill train station in July 2011, five days after she had been admitted to Wesley Hospital's eating disorder unit at Ashfield. Advertisement Ms Goldsmith managed to slip out of the clinic undetected twice on the day of her death, through an unmonitored exit. The Coroner found the clinic failed to complete a suicide risk assessment and did not obtain discharge summaries from Ms Goldsmith's previous admissions to hospital. "Her care and treatment was not at its … Continue reading

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Patient suicide: care 'not optimal' at health facility

Posted: Published on August 25th, 2014

Alana Goldsmith's mother, Judy, and sister Simone, at their home in Cammeray. Photo: Getty Images/Ben Rushton An eating disorder clinic made several mistakes in its treatment of a woman who escaped and killed herself - but the failures were not the ultimate cause of her death, a coroner has found. NSW Coroner Mark Douglass found Alana Goldsmith, 23, most likely killed herself as a result of her nine-year struggle with anorexia nervosa. "It is clear the mental illness/condition anorexia nervosa played a foundational role in Alana Goldsmith's decision and ultimately her tragic death," Mr Douglass said in findings handed down on Monday. Alana Goldsmith died after escaping from an eating disorders clinic in Ashfield. Photo: Supplied The former Barker College student died at Summer Hill train station in July 2011, five days after she had been admitted to Wesley Hospital's eating disorder unit at Ashfield. Advertisement Ms Goldsmith managed to slip out of the clinic undetected twice on the day of her death, through an unmonitored exit. The Coroner found the clinic failed to complete a suicide risk assessment and did not obtain discharge summaries from Ms Goldsmith's previous admissions to hospital. "Her care and treatment was not at its … Continue reading

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'Grief is overwhelming'

Posted: Published on August 25th, 2014

Alana Goldsmith's mother, Judy, and sister Simone, at their home in Cammeray. Photo: Getty Images/Ben Rushton An eating disorder clinic made several mistakes in its treatment of a woman who escaped and killed herself - but the failures were not the ultimate cause of her death, a coroner has found. NSW Coroner Mark Douglass found Alana Goldsmith, 23, most likely killed herself as a result of her nine-year struggle with anorexia nervosa. "It is clear the mental illness/condition anorexia nervosa played a foundational role in Alana Goldsmith's decision and ultimately her tragic death," Mr Douglass said in findings handed down on Monday. Alana Goldsmith died after escaping from an eating disorders clinic in Ashfield. Photo: Supplied The former Barker College student died at Summer Hill train station in July 2011, five days after she had been admitted to Wesley Hospital's eating disorder unit at Ashfield. Advertisement Ms Goldsmith managed to slip out of the clinic undetected twice on the day of her death, through an unmonitored exit. The Coroner found the clinic failed to complete a suicide risk assessment and did not obtain discharge summaries from Ms Goldsmith's previous admissions to hospital. "Her care and treatment was not at its … Continue reading

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Catholic Leaders Put A Chill On ALS Ice Bucket Challenge – Video

Posted: Published on August 25th, 2014

Catholic Leaders Put A Chill On ALS Ice Bucket Challenge Leaders are worried about embryonic stem cell research using aborted human fetuses. CBS 2's Lou Young reports. Official Site: http://newyork.cbslocal.com/ YouTube: http://www.youtube.com/user/CBS... By: CBS New York … Continue reading

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Mayor Bob Campbell ALS Ice Bucket Challenge – Video

Posted: Published on August 25th, 2014

Mayor Bob Campbell ALS Ice Bucket Challenge DeFuniak Springs, FL - Mayor Bob Campbell takes ALS Ice Bucket Challenge at City Hall on Friday, August 22nd, 2014. "My hope is that any stem cell research done, does not include an aborted... By: DFSPOLICE … Continue reading

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ALS Ice Bucket Challenge – Mallory Ranem – Video

Posted: Published on August 25th, 2014

ALS Ice Bucket Challenge - Mallory Ranem I was nominated by Carley Biniek and Jim Ranem; I nominate Tori Conners, Jessie Conners, and Brianna Sundgaard. In light of the ALSA's policy on Embryonic Stem Cell research, I'll be making... By: Dustin Ranem … Continue reading

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Genetic research facility opens its doors to the public

Posted: Published on August 25th, 2014

Genetic research will be in the spotlight next week when the most advanced genome sequencing facility in the Southern Hemisphere opens its doors to the public. A free public forum at The University of Queensland Diamantina Institute (UQDI) on Monday, 1 September will feature speakers highlighting medical, legal and ethical implications of advances in genome sequencing. Advances in genome sequencing allow health practitioners to better understand the genetic causes of many common human diseases. UQDI Director Professor Matthew Brown said the forum would bean excellent opportunity for members of the public to speak with genomics experts and learn more about genetic research being undertaken in Brisbane. Were keen to communicate the rapid advances being made in genomic research and the opportunities that genome sequencing presents for tailoring medical treatment to suit individuals, he said. This is a great opportunity to showcase the work of the UQ Centre for Clinical Genomics and help people understand how research conducted right here in Brisbane will benefit us all. Professor Brown said Health Minister Mr Lawrence Springborg would discuss the governments commitment to genome sequencing research and ethics at the event. Were excited that Minister Springborg can attend the forum to talk about why … Continue reading

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Shoebox IVF Treatment offers Hope at Lower Costs – Video

Posted: Published on August 25th, 2014

Shoebox IVF Treatment offers Hope at Lower Costs In South Africa, a pioneering new method of fertility treatment is bringing hope to the lives of many infertile couples. The Shoebox IVF treatment as its commonly known is essentially a low... By: CCTV Africa … Continue reading

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Do closed-loop insulin delivery systems improve blood glucose control in type 1 diabetes?

Posted: Published on August 25th, 2014

PUBLIC RELEASE DATE: 25-Aug-2014 Contact: Kathryn Ryan kryan@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News New Rochelle, NY, August 25, 2014In a closed-loop control approach to managing type 1 diabetes, glucose sensors placed under the skin continuously monitor blood sugar levels, triggering the release of insulin from an implantable insulin pump as needed. The aim of this closed-loop insulin delivery system is improved control of blood glucose levels throughout the day and night. But a new study in adults and adolescents found that mean blood glucose levels remained at safe levels 53-82% of the time, according to the results published in Diabetes Technology & Therapeutics (DTT), a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the DTT website at http://online.liebertpub.com/doi/full/10.1089/dia.2014.0066 until September 25, 2014. Howard Zisser, MD and an international team of researchers representing the Control to Range Study Group measured plasma glucose levels every 15-30 minutes in a group of individuals with type 1 diabetes who participated in the "Control to Range" multinational artificial pancreas study. They monitored the adults and teens over 22 hours, including three meals and periods of day and night. The authors describe the risks of hypo- and hyperglycemia, … Continue reading

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